JP5899206B2 - 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 - Google Patents
関節リウマチの治療のための可溶性ｃｄ２４の使用方法 Download PDFInfo
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- 238000010200 validation analysis Methods 0.000 description 1
- 125000002987 valine group Chemical group [H]N([H])C([H])(C(*)=O)C([H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 238000011100 viral filtration Methods 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Marine Sciences & Fisheries (AREA)
- Transplantation (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
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| US32907810P | 2010-04-28 | 2010-04-28 | |
| US61/329,078 | 2010-04-28 | ||
| PCT/US2011/034282 WO2011139820A1 (en) | 2010-04-28 | 2011-04-28 | Methods of use of soluble cd24 for therapy of rheumatoid arthritis |
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| JP2015137457A Division JP6062502B2 (ja) | 2010-04-28 | 2015-07-09 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
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| JP2015137457A Expired - Fee Related JP6062502B2 (ja) | 2010-04-28 | 2015-07-09 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2016242313A Withdrawn JP2017057216A (ja) | 2010-04-28 | 2016-12-14 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2018094404A Expired - Fee Related JP6526872B2 (ja) | 2010-04-28 | 2018-05-16 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2019088170A Expired - Fee Related JP6888221B2 (ja) | 2010-04-28 | 2019-05-08 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
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| JP2016242313A Withdrawn JP2017057216A (ja) | 2010-04-28 | 2016-12-14 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2018094404A Expired - Fee Related JP6526872B2 (ja) | 2010-04-28 | 2018-05-16 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
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Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130231464A1 (en) * | 2010-04-28 | 2013-09-05 | Oncolmmune, Inc. | Methods of use of soluble cd24 for therapy of rheumatoid arthritis |
| CN107531772B (zh) * | 2015-05-07 | 2021-09-21 | 肿瘤免疫股份有限公司 | Cd24用于降低低密度脂蛋白胆固醇水平的用途 |
| SG11201806338SA (en) * | 2016-02-02 | 2018-08-30 | Oncoimmune Inc | Use of cd24 proteins for treating leptin-deficient conditions |
| US10758574B2 (en) | 2016-04-28 | 2020-09-01 | The Board Of Trustees Of The Leland Stanford Junior University | Cartilage cells with a high regenerative potential and low immune response for use in cellular therapy |
| KR101789449B1 (ko) * | 2016-12-08 | 2017-10-23 | 박문수 | 폐유지를 이용한 지방산 메틸에스테르 제조방법 |
| CN110461353A (zh) * | 2017-03-07 | 2019-11-15 | 肿瘤免疫股份有限公司 | 可溶性cd24用于治疗系统性红斑狼疮的使用方法 |
| KR20200034957A (ko) * | 2017-05-15 | 2020-04-01 | 온코이뮨, 아이앤씨. | 신경 보호 및 재수초화를 위한 가용성 cd24의 사용 방법 |
| CN110799206A (zh) * | 2017-05-22 | 2020-02-14 | 肿瘤免疫股份有限公司 | 使用可溶性cd24治疗癌症疗法中免疫相关不良事件的方法 |
| AU2019231191A1 (en) * | 2018-03-05 | 2020-09-03 | Institute Of Biophysics, Chinese Academy Of Sciences | Methods of use of soluble CD24 for treating acquired immune deficiency syndrome (HIV/AIDS) |
| TWI835794B (zh) * | 2018-05-14 | 2024-03-21 | 美商昂科Ｃ４公司 | 抗cd24組合物及其用途 |
| EP3801773A4 (en) * | 2018-06-04 | 2022-03-16 | Oncoimmune, Inc. | METHOD OF USE OF CD24 FOR PREVENTION AND TREATMENT OF GRAFT VERSUS HOST DISEASE AND MUCOSITIS |
| EP4017508A1 (en) * | 2019-08-23 | 2022-06-29 | Sana Biotechnology, Inc. | Cd24 expressing cells and uses thereof |
| CN112480237B (zh) * | 2019-09-12 | 2023-10-17 | 上海津曼特生物科技有限公司 | 一种融合蛋白及其制备方法和应用 |
| US20250195673A1 (en) * | 2020-11-30 | 2025-06-19 | Fred Hutchinson Cancer Center | Compositions and methods for selective depletion of target molecules |
| EP4408862A4 (en) * | 2021-09-28 | 2025-11-12 | Acroimmune Guangzhou Biotech Ltd | Fusion proteins including the O71 core peptide and their use |
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| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US5541087A (en) * | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
| US5798448A (en) * | 1994-10-27 | 1998-08-25 | Genentech, Inc. | AL-1 neurotrophic factor antibodies |
| CN101254302B (zh) * | 1999-05-07 | 2011-05-11 | 杰南技术公司 | 使用与b细胞表面标志结合的拮抗剂治疗自身免疫病 |
| AU2001259792B2 (en) * | 2000-03-29 | 2005-12-22 | The Ohio State University Research Foundation | Methods of blocking tissue destruction by autoreactive T cells |
| US20030106084A1 (en) * | 2000-03-29 | 2003-06-05 | Yang Liu | Methods of blocking tissue destruction by autoreactive T cells |
| US20030095966A1 (en) * | 2000-03-29 | 2003-05-22 | Yang Liu | Method of blocking tissue destruction by autoreactive T cells |
| HUP0303171A2 (hu) * | 2001-02-19 | 2003-12-29 | Merck Patent Gmbh | Csökkentett immunogenitású mesterséges fehérjék |
| US20050214290A1 (en) * | 2001-03-29 | 2005-09-29 | Yang Liu | Methods of blocking tissue destruction by autoreactive T cells |
| CA2453406A1 (en) * | 2001-07-13 | 2003-01-23 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Methods for reducing immunogenicity of polypeptides |
| CA2505601C (en) * | 2002-11-15 | 2014-10-28 | Musc Foundation For Research Development | Complement receptor 2 targeted complement modulators |
| AU2007242919B8 (en) * | 2003-04-09 | 2011-11-10 | F. Hoffmann-La Roche Ag | Therapy of autoimmune disease in a patient with an inadequate response to a TNF-alpha inhibitor |
| NZ587776A (en) * | 2003-04-09 | 2012-03-30 | Genentech Inc | Therapy of autoimmune disease in a patient with an inadequate response to a TNF-alpha inhibitor using anti-CD20 antibody |
| EP1706507A4 (en) * | 2003-11-26 | 2008-02-20 | Univ Ohio State Res Found | THE RISK AND PROGRESSION OF MULTIPLE SCLEROSIS PREDICTING POLYMORPHS CD24 GENOTYPES |
| JP2008507591A (ja) * | 2004-05-21 | 2008-03-13 | ゼンコー・インコーポレイテッド | 免疫原性が改変されたＣ１ｑファミリーメンバータンパク質 |
| US20060160220A1 (en) * | 2004-11-12 | 2006-07-20 | Iogenetics | Retroviral vectors with introns |
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