JP2013525305A5 - - Google Patents
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- Publication number
- JP2013525305A5 JP2013525305A5 JP2013505156A JP2013505156A JP2013525305A5 JP 2013525305 A5 JP2013525305 A5 JP 2013525305A5 JP 2013505156 A JP2013505156 A JP 2013505156A JP 2013505156 A JP2013505156 A JP 2013505156A JP 2013525305 A5 JP2013525305 A5 JP 2013525305A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- multimeric ligand
- subject
- region
- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32512710P | 2010-04-16 | 2010-04-16 | |
| US61/325,127 | 2010-04-16 | ||
| US35176010P | 2010-06-04 | 2010-06-04 | |
| US61/351,760 | 2010-06-04 | ||
| US201161442582P | 2011-02-14 | 2011-02-14 | |
| US61/442,582 | 2011-02-14 | ||
| PCT/US2011/032572 WO2011130566A2 (en) | 2010-04-16 | 2011-04-14 | Method for treating solid tumors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016060361A Division JP2016117770A (ja) | 2010-04-16 | 2016-03-24 | 固形腫瘍を処置するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013525305A JP2013525305A (ja) | 2013-06-20 |
| JP2013525305A5 true JP2013525305A5 (https=) | 2014-05-01 |
| JP5975983B2 JP5975983B2 (ja) | 2016-08-23 |
Family
ID=44799326
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013505156A Expired - Fee Related JP5975983B2 (ja) | 2010-04-16 | 2011-04-14 | 固形腫瘍を処置するための方法 |
| JP2016060361A Withdrawn JP2016117770A (ja) | 2010-04-16 | 2016-03-24 | 固形腫瘍を処置するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016060361A Withdrawn JP2016117770A (ja) | 2010-04-16 | 2016-03-24 | 固形腫瘍を処置するための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20110287038A1 (https=) |
| EP (1) | EP2558109A4 (https=) |
| JP (2) | JP5975983B2 (https=) |
| AU (1) | AU2011239569B2 (https=) |
| CA (1) | CA2795947A1 (https=) |
| WO (1) | WO2011130566A2 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004073641A2 (en) | 2003-02-18 | 2004-09-02 | Kevin Slawin | Induced activation in dendritic cells |
| CA3058450A1 (en) | 2006-10-19 | 2008-04-24 | Baylor College Of Medicine | Generating an immune response by inducing cd40 and pattern recognition receptors |
| CA2738031C (en) * | 2008-09-22 | 2022-11-29 | Baylor College Of Medicine | Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters |
| ES2862340T3 (es) | 2009-10-29 | 2021-10-07 | Sanofi Mature Ip | Nuevo uso antitumoral de cabazitaxel |
| US9089520B2 (en) | 2010-05-21 | 2015-07-28 | Baylor College Of Medicine | Methods for inducing selective apoptosis |
| MX350807B (es) | 2011-11-29 | 2017-09-20 | Genentech Inc | Composiciones y metodos para el analisis de cancer de prostata. |
| AU2013204922B2 (en) | 2012-12-20 | 2015-05-14 | Celgene Corporation | Chimeric antigen receptors |
| US9434935B2 (en) | 2013-03-10 | 2016-09-06 | Bellicum Pharmaceuticals, Inc. | Modified caspase polypeptides and uses thereof |
| CA2905352A1 (en) * | 2013-03-14 | 2014-09-25 | Bellicum Pharmaceuticals, Inc. | Methods for controlling t cell proliferation |
| KR20150130284A (ko) * | 2013-03-15 | 2015-11-23 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 암 백신 및 이를 이용한 치료 방법 |
| EP2968448A4 (en) * | 2013-03-15 | 2016-02-17 | Univ Pennsylvania | COMPOSITIONS USING HYPOXY-INDUCIBLE FACTOR 1-ALPHA AND METHOD OF USE THEREOF |
| JP6493692B2 (ja) | 2013-03-15 | 2019-04-10 | セルジーン コーポレイション | 修飾されたtリンパ球 |
| ES2791598T3 (es) | 2013-06-05 | 2020-11-05 | Bellicum Pharmaceuticals Inc | Métodos para inducir apoptosis parcial utilizando polipéptidos de caspasa |
| JP6496472B2 (ja) * | 2013-07-03 | 2019-04-03 | 三菱重工機械システム株式会社 | 車載器、及びスプーフィング検知方法 |
| US10934346B2 (en) * | 2014-02-14 | 2021-03-02 | Bellicum Pharmaceuticals, Inc. | Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12 |
| EP2940136A1 (en) * | 2014-04-30 | 2015-11-04 | QIAGEN GmbH | Method for isolating poly(A) nucleic acids |
| AU2015312117A1 (en) * | 2014-09-02 | 2017-03-02 | Bellicum Pharmaceuticals, Inc. | Costimulation of chimeric antigen receptors by Myd88 and CD40 polypeptides |
| JP6718444B2 (ja) | 2014-11-03 | 2020-07-08 | アカデミッシュ ザイケンホイス レイデン (エイチ.オー.ディー.エヌ. エルユーエムシー) | Bob1に対して指向されるT細胞レセプターおよびその使用 |
| US10975137B2 (en) * | 2014-11-06 | 2021-04-13 | University Of Maryland, Baltimore | CD8a and t cell receptor variants and methods of using same in modulating immune cell responses |
| HK1245827B (en) * | 2014-12-15 | 2020-06-19 | Board Of Regents Of The University Of Texas System | Methods for controlled activation or elimination of therapeutic cells |
| US20170151281A1 (en) | 2015-02-19 | 2017-06-01 | Batu Biologics, Inc. | Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer |
| WO2017015553A1 (en) * | 2015-07-22 | 2017-01-26 | University Of Washington | Compositions and methods for producing pro-inflammatory macrophages |
| IL315940A (en) | 2015-07-28 | 2024-11-01 | Univ Pennsylvania | Altered monocytes/macrophages expressing chimeric antigen receptors and their uses |
| US11266726B2 (en) * | 2015-10-30 | 2022-03-08 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compositions and methods for the treatment of HER2-expressing solid tumors |
| JP6904667B2 (ja) | 2016-06-14 | 2021-07-21 | 日本光電工業株式会社 | バイトブロック及びガスセンサキット |
| WO2018077385A1 (en) * | 2016-10-25 | 2018-05-03 | Biontech Rna Pharmaceuticals Gmbh | Dose determination for immunotherapeutic agents |
| EP3621988A1 (en) | 2017-05-09 | 2020-03-18 | Bellicum Pharmaceuticals, Inc. | Methods to augment or alter signal transduction |
| EP3675902A4 (en) * | 2017-08-28 | 2021-06-23 | Board of Trustees of Michigan State University | Compositions and methods of treating cancer and infections using bacteriophage and its mutants |
| WO2019067805A1 (en) | 2017-09-27 | 2019-04-04 | University Of Southern California | NEW PLATFORMS FOR CO-STIMULATION, NEW CAR DESIGNS AND OTHER IMPROVEMENTS FOR ADOPTIVE CELL THERAPY |
| WO2019113509A2 (en) | 2017-12-08 | 2019-06-13 | Bellicum Pharmaceuticals, Inc. | Methods for enhancing and maintaining car-t cell efficacy |
| US20200308144A1 (en) | 2017-12-20 | 2020-10-01 | Bellicum Pharmaceuticals, Inc. | Multimeric piperidine derivatives |
| US20220000921A1 (en) * | 2018-11-20 | 2022-01-06 | Innovative Cellular Therapeutics Holdings, Ltd. | Modified Cell Expressing Therapeutic Agent and Uses thereof |
| CN114981409A (zh) | 2019-09-03 | 2022-08-30 | 美洛德生物医药公司 | 用于基因组整合的方法和组合物 |
| WO2021119538A1 (en) * | 2019-12-11 | 2021-06-17 | Myeloid Therapeutics, Inc. | Therapeutic cell compositions and methods for manufacture and uses thereof |
| US10980836B1 (en) | 2019-12-11 | 2021-04-20 | Myeloid Therapeutics, Inc. | Therapeutic cell compositions and methods of manufacturing and use thereof |
| WO2021142305A2 (en) * | 2020-01-10 | 2021-07-15 | Coimmune, Inc. | Methods of treating tumors |
| JP7735291B2 (ja) | 2020-02-21 | 2025-09-08 | エーアールエス ファーマシューティカルズ、インコーポレイテッド | ネクチン-4抗体コンジュゲートおよびその使用 |
| EP4161536A4 (en) | 2020-06-04 | 2024-08-14 | Carisma Therapeutics Inc. | Novel constructs for chimeric antigen receptors |
| JP2023532304A (ja) | 2020-07-01 | 2023-07-27 | エーアールエス ファーマシューティカルズ オペレーションズ,インク. | 抗asgr1抗体コンジュゲートおよびその使用 |
| EP4240367A4 (en) | 2020-11-04 | 2024-10-16 | Myeloid Therapeutics, Inc. | MODIFIED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF |
| WO2022197949A2 (en) | 2021-03-17 | 2022-09-22 | Myeloid Therapeutics, Inc. | Engineered chimeric fusion protein compositions and methods of use thereof |
| BR112023023642A2 (pt) | 2021-05-11 | 2024-01-30 | Myeloid Therapeutics Inc | Métodos e composições para integração genômica |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050215472A1 (en) * | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
| WO2004073641A2 (en) * | 2003-02-18 | 2004-09-02 | Kevin Slawin | Induced activation in dendritic cells |
| DE602004025726D1 (de) * | 2003-11-14 | 2010-04-08 | Genvec Inc | Pharmazeutische verbindung zur behandlung von lokal fortgeschrittenem primär inoperablen pankreaskarzinom (lapc). |
| CA3058450A1 (en) * | 2006-10-19 | 2008-04-24 | Baylor College Of Medicine | Generating an immune response by inducing cd40 and pattern recognition receptors |
| CN101888856B (zh) * | 2007-11-07 | 2014-08-27 | 塞尔德克斯医疗公司 | 结合人树突和上皮细胞205(dec-205)的抗体 |
| WO2009111507A1 (en) * | 2008-03-03 | 2009-09-11 | Dyax Corp. | Metalloproteinase 12 binding proteins |
| WO2009151503A2 (en) * | 2008-04-10 | 2009-12-17 | University Of Florida Research Foundation, Inc. | Compositions and methods for the treatment of a neoplasia |
| CA2738031C (en) * | 2008-09-22 | 2022-11-29 | Baylor College Of Medicine | Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters |
-
2011
- 2011-04-14 US US13/087,329 patent/US20110287038A1/en not_active Abandoned
- 2011-04-14 CA CA2795947A patent/CA2795947A1/en not_active Abandoned
- 2011-04-14 AU AU2011239569A patent/AU2011239569B2/en not_active Ceased
- 2011-04-14 JP JP2013505156A patent/JP5975983B2/ja not_active Expired - Fee Related
- 2011-04-14 WO PCT/US2011/032572 patent/WO2011130566A2/en not_active Ceased
- 2011-04-14 EP EP11769619.5A patent/EP2558109A4/en not_active Withdrawn
-
2013
- 2013-03-06 US US13/786,652 patent/US20140023647A1/en not_active Abandoned
-
2016
- 2016-03-24 JP JP2016060361A patent/JP2016117770A/ja not_active Withdrawn
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