JP2013523827A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013523827A5 JP2013523827A5 JP2013503881A JP2013503881A JP2013523827A5 JP 2013523827 A5 JP2013523827 A5 JP 2013523827A5 JP 2013503881 A JP2013503881 A JP 2013503881A JP 2013503881 A JP2013503881 A JP 2013503881A JP 2013523827 A5 JP2013523827 A5 JP 2013523827A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- substituent
- amino
- chitosan
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CCC(C)(C(C(C*)C1O)OC(CO)C1OC(C)(CC)C(C(C1O)N*)OC(CO)C1O)OC(C(CO)OC(C1N*)O)C1O Chemical compound CCC(C)(C(C(C*)C1O)OC(CO)C1OC(C)(CC)C(C(C1O)N*)OC(CO)C1O)OC(C(CO)OC(C1N*)O)C1O 0.000 description 4
- FADKJNSSIWTVAI-SSDOTTSWSA-N CC([C@@H](CCCCN)N)=O Chemical compound CC([C@@H](CCCCN)N)=O FADKJNSSIWTVAI-SSDOTTSWSA-N 0.000 description 1
- IYXLCEMDYUFNBJ-QMMMGPOBSA-N CCCC([C@H](CCCCN)N)=O Chemical compound CCCC([C@H](CCCCN)N)=O IYXLCEMDYUFNBJ-QMMMGPOBSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32143710P | 2010-04-06 | 2010-04-06 | |
| US61/321,437 | 2010-04-06 | ||
| US201161451430P | 2011-03-10 | 2011-03-10 | |
| US61/451,430 | 2011-03-10 | ||
| PCT/US2011/031385 WO2011127144A1 (en) | 2010-04-06 | 2011-04-06 | Methods and compositions for treating wounds utilizing chitosan compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015077340A Division JP6000397B2 (ja) | 2010-04-06 | 2015-04-06 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013523827A JP2013523827A (ja) | 2013-06-17 |
| JP2013523827A5 true JP2013523827A5 (enExample) | 2014-04-03 |
Family
ID=44763261
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013503881A Pending JP2013523827A (ja) | 2010-04-06 | 2011-04-06 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
| JP2015077340A Active JP6000397B2 (ja) | 2010-04-06 | 2015-04-06 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
| JP2015237188A Withdrawn JP2016033164A (ja) | 2010-04-06 | 2015-12-04 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
| JP2017194973A Withdrawn JP2017226706A (ja) | 2010-04-06 | 2017-10-05 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015077340A Active JP6000397B2 (ja) | 2010-04-06 | 2015-04-06 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
| JP2015237188A Withdrawn JP2016033164A (ja) | 2010-04-06 | 2015-12-04 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
| JP2017194973A Withdrawn JP2017226706A (ja) | 2010-04-06 | 2017-10-05 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US9439925B2 (enExample) |
| EP (1) | EP2555760B1 (enExample) |
| JP (4) | JP2013523827A (enExample) |
| AU (1) | AU2011237682B2 (enExample) |
| CA (1) | CA2795520C (enExample) |
| ES (1) | ES2773017T3 (enExample) |
| WO (1) | WO2011127144A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2848648C (en) | 2006-06-02 | 2017-10-10 | Synedgen, Inc. | Chitosan-derivative compounds and methods of controlling microbial populations |
| CA3004707C (en) | 2009-09-02 | 2022-05-31 | Synedgen Inc. | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds |
| ES2773017T3 (es) | 2010-04-06 | 2020-07-09 | Synedgen Inc | Derivados de quitosano para el tratamiento de mucositis o ulceración |
| US20150031610A1 (en) * | 2012-03-05 | 2015-01-29 | Synedgen, Inc. | Derivatized polyglucosamines for delivery of small molecules, peptides, and proteins |
| CN102755662B (zh) * | 2012-07-25 | 2014-01-08 | 福州乾正药业有限公司 | 一种复合壳聚糖凝胶膜及其制备方法 |
| US10022393B2 (en) * | 2012-09-20 | 2018-07-17 | Synedgen, Inc. | Methods for treatment or prevention of damage resulting from radiation, trauma or shock |
| TWI478943B (zh) * | 2012-12-27 | 2015-04-01 | Ind Tech Res Inst | 高分子組成物用於製備具有抑制基質金屬蛋白酶之活性的功效的醫療器材或抑制劑的用途 |
| CN103893813B (zh) * | 2012-12-28 | 2018-04-17 | 财团法人工业技术研究院 | 高分子组合物与高分子材料 |
| CA2905404C (en) | 2013-03-12 | 2021-07-20 | Synedgen, Inc. | Oral formulations of polyglucosamine derivatives in combination with a non-fermentable sugar |
| WO2014172040A1 (en) * | 2013-03-15 | 2014-10-23 | Synedgen Inc. | Compositions and methods of use for wound healing |
| WO2015022907A1 (ja) * | 2013-08-13 | 2015-02-19 | 生化学工業株式会社 | カチオン化キトサンを含有する医薬 |
| US9259357B2 (en) | 2014-04-16 | 2016-02-16 | Loma Linda University | Composition, preparation, and use of chitosan shards for biomedical applications |
| AU2015314775A1 (en) | 2014-09-11 | 2017-03-30 | Synedgen, Inc. | Compositions and methods of use thereof |
| CN108348455B (zh) * | 2015-10-30 | 2021-04-09 | 克罗马药品股份有限公司 | 无菌水性眼用溶液的治疗用途 |
| PL3368006T3 (pl) * | 2015-10-30 | 2020-06-01 | Croma-Pharma Gesellschaft M.B.H. | Zastosowanie terapeutyczne sterylnego wodnego roztworu oftalmicznego |
| EP3429602B1 (en) * | 2016-03-16 | 2025-05-07 | Synedgen, Inc. | Compositions comprising a polyglucosamine-arginine and their use to treat dysbiosis |
| CN108096182A (zh) * | 2016-11-25 | 2018-06-01 | 哈尔滨盈聚生物科技有限公司 | 一种基于绿色抗菌材料的妇科抗菌凝胶及其制备方法 |
| US10918699B2 (en) * | 2017-03-22 | 2021-02-16 | Michael C. Struck | Therapeutic treatment for neurotrophic keratopathy |
| WO2018202783A1 (en) | 2017-05-03 | 2018-11-08 | Croma-Pharma Gmbh | Sterile aqueous ophthalmic solution containing n-(n-acetylcysteinyl)-chitosan for treating non-infectious corneal disorders |
| TWI633888B (zh) * | 2017-10-03 | 2018-09-01 | 黃琮瑋 | 醣類物質用於製備改善嗅覺功能的藥物之用途 |
| CN107970269A (zh) * | 2017-12-30 | 2018-05-01 | 广州润虹医药科技股份有限公司 | 一种含有壳聚糖的口腔溃疡膜及其制备方法 |
| RU2697869C1 (ru) * | 2018-04-28 | 2019-08-21 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) | Фармацевтическая субстанция для лечения инфицированных ран различного генеза |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| AU2020444897A1 (en) | 2020-04-30 | 2022-12-08 | Synedgen, Inc. | Compositions and methods of use thereof |
| EP4406542A1 (en) | 2023-01-26 | 2024-07-31 | BioKuris | Treatment of gut inflammatory diseases |
| WO2026128424A1 (en) * | 2024-12-10 | 2026-06-18 | Immunophotonics, Inc | Compositions of chitosan and modified chitosans |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4409205A (en) * | 1979-03-05 | 1983-10-11 | Cooper Laboratories, Inc. | Ophthalmic solution |
| US4532134A (en) | 1981-04-06 | 1985-07-30 | Malette William Graham | Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound |
| CA2181048C (en) * | 1994-01-14 | 2003-05-06 | Lee Shahinian, Jr. | A method for sustained and extended corneal analgesia |
| US7214202B1 (en) | 1997-07-28 | 2007-05-08 | Kci Licensing, Inc. | Therapeutic apparatus for treating ulcers |
| EP1061937A1 (en) | 1998-03-10 | 2000-12-27 | University Of Southern California | Improved radiation therapy methods |
| PT1100344E (pt) | 1998-07-30 | 2004-09-30 | Vital Living Inc | Novas composicoes liquidas contendo quitosana e metodos para a sua preparacao e utilizacao |
| US6114382A (en) | 1998-11-11 | 2000-09-05 | Moretti; Itagiba G. | Methods for treating inflammatory bowel disease |
| PT1128809E (pt) * | 1998-11-20 | 2005-04-29 | Medidom Lab | Formulacoes oftalmicas aquosas comprendendo quitosano |
| US6962151B1 (en) | 1999-11-05 | 2005-11-08 | Pari GmbH Spezialisten für effektive Inhalation | Inhalation nebulizer |
| JP2003012702A (ja) | 2001-04-24 | 2003-01-15 | Sankyo Co Ltd | 低分子キトサンの製造方法 |
| US20060127873A1 (en) | 2002-07-16 | 2006-06-15 | Caroline Hoemann | Composition for cytocompatible, injectable, self-gelling chitosan solutions for encapsulating and delivering live cells or biologically active factors |
| GB2393120A (en) | 2002-09-18 | 2004-03-24 | Johnson & Johnson Medical Ltd | Compositions for wound treatment |
| GB0302741D0 (en) | 2003-02-06 | 2003-03-12 | Advanced Biopolymers As | Use |
| GB0303085D0 (en) | 2003-02-11 | 2003-03-19 | Pfizer Ltd | Model |
| EP1771138A4 (en) | 2004-07-26 | 2009-08-19 | Kci Licensing Inc | METHOD FOR COVERING ANTIMICROBIAL AGENT SUBSTRATE AND PRODUCT THUS FORMED |
| CN1965650A (zh) | 2005-11-14 | 2007-05-23 | 陈祖辉 | 多元金属离子螯合的甲壳素绿色抗菌剂 |
| CA2848648C (en) * | 2006-06-02 | 2017-10-10 | Synedgen, Inc. | Chitosan-derivative compounds and methods of controlling microbial populations |
| WO2009094172A2 (en) | 2008-01-22 | 2009-07-30 | Araim Pharmaceuticals, Inc. | Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage |
| WO2009136291A2 (en) * | 2008-05-09 | 2009-11-12 | Regenics As | Cellular extracts |
| WO2010021930A1 (en) | 2008-08-16 | 2010-02-25 | Synedgen, Inc. | Prevention and treatment of mrsa infections with chitosan-derivatives |
| CA2732438A1 (en) | 2008-08-29 | 2010-03-04 | The General Hospital Corporation | Methods of modulating gastrointestinal tract flora levels with alkaline phosphatase |
| CA2743624C (en) | 2008-11-12 | 2017-06-20 | Synedgen, Inc. | Chitosan derivatives to treat animals or optimize animal health |
| EP2387409A1 (en) | 2008-11-12 | 2011-11-23 | Synedgen, Inc. | Chitosan derivatives alone or in combination for the treatment of mdr microbial infections |
| WO2010088565A1 (en) | 2009-01-29 | 2010-08-05 | Synedgen, Inc. | Nucleic acid delivery using modified chitosans |
| AU2010259284A1 (en) | 2009-06-10 | 2011-12-15 | Exthera Ab | Use of a composition for the treatment of mucositis |
| CA3004707C (en) | 2009-09-02 | 2022-05-31 | Synedgen Inc. | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds |
| WO2011028968A1 (en) | 2009-09-02 | 2011-03-10 | Synedgen, Inc. | Oral care methods and compositions utilizing chitosan-derivative compounds |
| ES2773017T3 (es) | 2010-04-06 | 2020-07-09 | Synedgen Inc | Derivados de quitosano para el tratamiento de mucositis o ulceración |
| CA2840749A1 (en) | 2011-07-01 | 2013-01-10 | Synedgen, Inc. | Methods and compositions of reducing and preventing bacterial growth and the formation of biofilm on a surface utilizing chitosan-derivative compounds |
| US8735571B2 (en) | 2011-12-22 | 2014-05-27 | Agenta Biotechnologies, Inc. | Composition, preparation, and use of dense chitosan membrane materials |
| US20150031610A1 (en) | 2012-03-05 | 2015-01-29 | Synedgen, Inc. | Derivatized polyglucosamines for delivery of small molecules, peptides, and proteins |
| US10022393B2 (en) | 2012-09-20 | 2018-07-17 | Synedgen, Inc. | Methods for treatment or prevention of damage resulting from radiation, trauma or shock |
| CA2905404C (en) | 2013-03-12 | 2021-07-20 | Synedgen, Inc. | Oral formulations of polyglucosamine derivatives in combination with a non-fermentable sugar |
| WO2014172040A1 (en) | 2013-03-15 | 2014-10-23 | Synedgen Inc. | Compositions and methods of use for wound healing |
| AU2015314775A1 (en) | 2014-09-11 | 2017-03-30 | Synedgen, Inc. | Compositions and methods of use thereof |
| WO2018202783A1 (en) | 2017-05-03 | 2018-11-08 | Croma-Pharma Gmbh | Sterile aqueous ophthalmic solution containing n-(n-acetylcysteinyl)-chitosan for treating non-infectious corneal disorders |
| US11390408B2 (en) | 2020-11-24 | 2022-07-19 | Axon Llc | System and method for applying tubular bands to containers utilizing angled band ejection |
-
2011
- 2011-04-06 ES ES11766639T patent/ES2773017T3/es active Active
- 2011-04-06 EP EP11766639.6A patent/EP2555760B1/en active Active
- 2011-04-06 AU AU2011237682A patent/AU2011237682B2/en active Active
- 2011-04-06 WO PCT/US2011/031385 patent/WO2011127144A1/en not_active Ceased
- 2011-04-06 US US13/639,560 patent/US9439925B2/en active Active
- 2011-04-06 CA CA2795520A patent/CA2795520C/en active Active
- 2011-04-06 JP JP2013503881A patent/JP2013523827A/ja active Pending
-
2015
- 2015-04-06 JP JP2015077340A patent/JP6000397B2/ja active Active
- 2015-12-04 JP JP2015237188A patent/JP2016033164A/ja not_active Withdrawn
-
2016
- 2016-06-03 US US15/173,218 patent/US20170119810A1/en not_active Abandoned
-
2017
- 2017-10-05 JP JP2017194973A patent/JP2017226706A/ja not_active Withdrawn
-
2018
- 2018-03-16 US US15/923,696 patent/US11717532B2/en active Active
-
2023
- 2023-06-13 US US18/333,968 patent/US20240197769A1/en not_active Abandoned
-
2024
- 2024-12-20 US US18/989,494 patent/US20250345355A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Gatot et al. | Effects of sodium hypochlorite on soft tissues after its inadvertent injection beyond the root apex | |
| US9655840B2 (en) | Wound care products | |
| JP6027013B2 (ja) | グルカン組成物 | |
| JP2006503044A5 (enExample) | ||
| EP2037908A2 (en) | Method for treatment of wound using aganocides | |
| CN105451745A (zh) | 含有阳离子化壳聚糖的药物 | |
| KR20160067120A (ko) | 비자가접착성 코팅 물질 | |
| JP2017501154A5 (enExample) | ||
| CN108478544A (zh) | 一种黏膜疾病治疗系统及其应用 | |
| WO2011092715A3 (en) | Method for in-vivo binding of chromatin fragments | |
| RU2009107068A (ru) | Применение пропиленгликоля при лечении связанных с воспалением местных нарушений или заболеваний и ран | |
| Jia et al. | Dynamic microenvironment-adaptable hydrogel with photothermal performance and ROS scavenging for management of diabetic ulcer | |
| JP2014518272A5 (enExample) | ||
| CN108210689A (zh) | 一种含有透明质酸的口腔溃疡膜剂及其制备方法 | |
| WO2021110063A1 (en) | New conjugates of peptides and polysaccharide | |
| PT1532986E (pt) | Composição farmacêutica para o tratamento de rinite | |
| EP4157290A1 (en) | Compositions, their uses in therapy and methods thereof | |
| WO1998029125A1 (fr) | Remedes contre des troubles de la vessie | |
| JP2012526099A5 (enExample) | ||
| CN112368304A (zh) | 经取代的环糊精-金属络合物及其用途 | |
| RU2012116226A (ru) | Бронхолитическое средство на основе простагландина | |
| HUP0900717A2 (en) | Pharmaceutical composition for urological use containing zinc hyaluronate | |
| CN104740691A (zh) | 一种医用生物胶体液及其制备方法 | |
| JP2016093467A (ja) | 創傷治癒を促進し生体諸臓器の被覆（コーチング）及び庇護を目的とした生体皮膜剤。 | |
| WO2014155074A1 (en) | Composition |