JP2013523678A5 - - Google Patents
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- Publication number
- JP2013523678A5 JP2013523678A5 JP2013501783A JP2013501783A JP2013523678A5 JP 2013523678 A5 JP2013523678 A5 JP 2013523678A5 JP 2013501783 A JP2013501783 A JP 2013501783A JP 2013501783 A JP2013501783 A JP 2013501783A JP 2013523678 A5 JP2013523678 A5 JP 2013523678A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- pharmaceutical composition
- dione
- methyl
- pkc inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31901310P | 2010-03-30 | 2010-03-30 | |
| US61/319,013 | 2010-03-30 | ||
| US201061425525P | 2010-12-21 | 2010-12-21 | |
| US61/425,525 | 2010-12-21 | ||
| PCT/EP2011/054709 WO2011120911A1 (en) | 2010-03-30 | 2011-03-28 | Pkc inhibitors for the treatment of b-cell lymphoma having chronic active b-cell-receptor signalling |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013523678A JP2013523678A (ja) | 2013-06-17 |
| JP2013523678A5 true JP2013523678A5 (https=) | 2014-05-15 |
Family
ID=44710357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013501783A Pending JP2013523678A (ja) | 2010-03-30 | 2011-03-28 | 慢性的に活性なｂ細胞受容体シグナル伝達を有するｂ細胞リンパ腫の治療用のｐｋｃ阻害薬 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8748428B2 (https=) |
| EP (1) | EP2552428A1 (https=) |
| JP (1) | JP2013523678A (https=) |
| KR (2) | KR101461767B1 (https=) |
| CN (1) | CN102821759A (https=) |
| AR (1) | AR080737A1 (https=) |
| AU (1) | AU2011234644B2 (https=) |
| BR (1) | BR112012024585A2 (https=) |
| CA (1) | CA2795456A1 (https=) |
| MX (1) | MX2012011341A (https=) |
| RU (1) | RU2012146083A (https=) |
| WO (1) | WO2011120911A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4556010A3 (en) | 2011-11-30 | 2025-07-23 | Emory University | Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae |
| KR101723786B1 (ko) | 2014-03-28 | 2017-04-06 | 가톨릭대학교 산학협력단 | Ｉｌ―２１을 발현하는 중간엽 줄기세포를 포함하는 ｂ 세포 림프종 예방 또는 치료용 조성물 |
| JO3589B1 (ar) | 2014-08-06 | 2020-07-05 | Novartis Ag | مثبطات كيناز البروتين c وطرق استخداماتها |
| JP2019524700A (ja) * | 2016-07-14 | 2019-09-05 | ミングサイト ファーマシューティカルズ，インク． | 癌の処置 |
| CN110496223B (zh) * | 2018-05-17 | 2021-09-10 | 复旦大学附属肿瘤医院 | 一种治疗非霍奇金氏淋巴瘤的药物组合物 |
| WO2020092924A1 (en) * | 2018-11-02 | 2020-05-07 | Board Of Regents, The University Of Texas System | Combination therapy for the treatment of egfr tyrosine kinase inhibitor resistant cancer |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5489608A (en) | 1989-12-21 | 1996-02-06 | Goedecke Aktiengesellschaft | Indolocarbazole derivatives and the use thereof |
| US5475085A (en) | 1991-02-07 | 1995-12-12 | Molecumetics, Ltd. | Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same |
| NO308798B1 (no) | 1993-12-07 | 2000-10-30 | Lilly Co Eli | Proteinkinase-C-hemmere, anvendelse av samme for fremstilling av farmasøytika samt farmasøytisk formulering omfattende samme |
| US5545636A (en) | 1993-12-23 | 1996-08-13 | Eli Lilly And Company | Protein kinase C inhibitors |
| ES2236702T3 (es) | 1993-12-23 | 2005-07-16 | Eli Lilly And Company | Inhibidores de la proteina quinasa c. |
| YU49315B (sh) | 1995-11-20 | 2005-06-10 | Elli Lilly And Company | Inhibitor protein kinaze c, njegove farmaceutske formulacije i postupak za dobijanje |
| US6645970B2 (en) | 2000-11-07 | 2003-11-11 | Novartis Ag | Indolylmaleimide derivatives |
| AU2002221810B2 (en) | 2000-11-07 | 2005-06-23 | Novartis Ag | Indolylmaleimide derivatives as protein kinase C inhibitors |
| JP4547911B2 (ja) | 2002-02-01 | 2010-09-22 | アリアド・ファーマシューティカルズ・インコーポレイテッド | リン含有化合物およびその用途 |
| PE20040079A1 (es) | 2002-04-03 | 2004-04-19 | Novartis Ag | Derivados de indolilmaleimida |
| AU2004230952A1 (en) | 2003-04-09 | 2004-10-28 | Millenium Pharmaceuticals, Inc. | Beta-carbolines useful for treating inflammatory disease |
| GB0308466D0 (en) | 2003-04-11 | 2003-05-21 | Novartis Ag | Organic compounds |
| DE602004014965D1 (de) | 2003-10-24 | 2008-08-21 | Lilly Co Eli | Bisindolylmaleimid zur behandlung von prostatakrebs und akt-vermittelten erkrankungen |
| PE20060608A1 (es) | 2004-10-13 | 2006-08-22 | Wyeth Corp | Analogos de 17-hidroxiwortmanina como inhibidores de pi3k |
| AU2006217744A1 (en) | 2005-02-25 | 2006-08-31 | Kudos Pharmaceuticals Limited | 2,4-diamino-pyridopyrimidine derivatives and their use as MTOR inhibitors |
| AU2006217742A1 (en) | 2005-02-25 | 2006-08-31 | Kudos Pharmaceuticals Limited | Hydrazinomethyl, HYDR zonomethyl and 5-membered heterocylic compounds which act as MTOR inhibitors and their use as anti cancer agents |
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| AU2006268908A1 (en) * | 2005-07-11 | 2007-01-18 | Novartis Ag | Indolylmaleimide derivatives |
| CN103626742B (zh) | 2005-11-01 | 2017-04-26 | 塔格根公司 | 激酶的联-芳基间-嘧啶抑制剂 |
| PL1954699T3 (pl) | 2005-11-22 | 2013-01-31 | Kudos Pharm Ltd | Pochodne pirydo-, pirazo- i pirymidopirymidyny jako inhibitory mTOR |
| GB0526246D0 (en) | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
| JP2009523161A (ja) | 2006-01-11 | 2009-06-18 | アストラゼネカ アクチボラグ | モルホリノピリミジン誘導体と療法におけるその使用 |
| KR101438245B1 (ko) | 2006-08-23 | 2014-09-04 | 쿠도스 파마슈티칼스 리미티드 | Ｍｔｏｒ 억제제로서의 2-메틸모르폴린 피리도-, 피라조- 및 피리미도-피리미딘 유도체 |
| WO2008070740A1 (en) | 2006-12-07 | 2008-06-12 | F.Hoffmann-La Roche Ag | Phosphoinositide 3-kinase inhibitor compounds and methods of use |
| AR066879A1 (es) | 2007-06-08 | 2009-09-16 | Novartis Ag | Derivados de quinoxalina como inhibidores de la actividad de cinasa de tirosina de las cinasas janus |
| AU2008298948B2 (en) | 2007-09-12 | 2014-09-04 | F. Hoffmann-La Roche Ag | Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents, and methods of use |
| US8354528B2 (en) | 2007-10-25 | 2013-01-15 | Genentech, Inc. | Process for making thienopyrimidine compounds |
| ES2660418T3 (es) | 2008-07-16 | 2018-03-22 | Pharmacyclics Llc | Inhibidores de la tirosina quinasa de Bruton para el tratamiento de tumores sólidos |
-
2011
- 2011-03-28 CN CN2011800155365A patent/CN102821759A/zh active Pending
- 2011-03-28 RU RU2012146083/15A patent/RU2012146083A/ru not_active Application Discontinuation
- 2011-03-28 MX MX2012011341A patent/MX2012011341A/es not_active Application Discontinuation
- 2011-03-28 WO PCT/EP2011/054709 patent/WO2011120911A1/en not_active Ceased
- 2011-03-28 KR KR1020127025582A patent/KR101461767B1/ko not_active Expired - Fee Related
- 2011-03-28 CA CA2795456A patent/CA2795456A1/en not_active Abandoned
- 2011-03-28 EP EP11713996A patent/EP2552428A1/en not_active Withdrawn
- 2011-03-28 US US13/073,652 patent/US8748428B2/en not_active Expired - Fee Related
- 2011-03-28 BR BR112012024585A patent/BR112012024585A2/pt not_active IP Right Cessation
- 2011-03-28 KR KR1020147022716A patent/KR20140107685A/ko not_active Withdrawn
- 2011-03-28 JP JP2013501783A patent/JP2013523678A/ja active Pending
- 2011-03-28 AU AU2011234644A patent/AU2011234644B2/en not_active Ceased
- 2011-03-30 AR ARP110101038A patent/AR080737A1/es unknown
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