JP2013522311A - シクロスポリンおよび芳香族カチオン性ペプチドを用いた併用療法 - Google Patents
シクロスポリンおよび芳香族カチオン性ペプチドを用いた併用療法 Download PDFInfo
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Public Health (AREA)
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- Animal Behavior & Ethology (AREA)
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- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
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| US31394510P | 2010-03-15 | 2010-03-15 | |
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| US37681310P | 2010-08-25 | 2010-08-25 | |
| US61/376,813 | 2010-08-25 | ||
| PCT/US2011/028543 WO2011116007A1 (en) | 2010-03-15 | 2011-03-15 | Combination therapies using cyclosporine and aromatic cationic peptides |
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| JP2013522311A true JP2013522311A (ja) | 2013-06-13 |
| JP2013522311A5 JP2013522311A5 (https=) | 2014-05-01 |
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| US (4) | US8697657B2 (https=) |
| EP (6) | EP3375449A1 (https=) |
| JP (1) | JP2013522311A (https=) |
| WO (1) | WO2011116007A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022511939A (ja) * | 2018-12-18 | 2022-02-01 | ステルス バイオセラピューティクス コーポレーション | ミトコンドリア標的化ペプチド |
| JP2022517636A (ja) * | 2019-01-20 | 2022-03-09 | ファーサイト メディカル テクノロジー （シャンハイ） カンパニー リミテッド | シクロスポリン類似体及びその使用 |
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|---|---|---|---|---|
| CN103751763A (zh) * | 2009-12-31 | 2014-04-30 | 康肽德生物医药技术有限公司 | 用于预防或治疗血管阻塞损伤的方法 |
| EP3266462A1 (en) * | 2009-12-31 | 2018-01-10 | Stealth Peptides International, Inc. | Methods for performing a coronary artery bypass graft procedure |
| EP3375449A1 (en) | 2010-03-15 | 2018-09-19 | Stealth Peptides International, Inc. | Combination therapies using cyclosporine and aromatic cationic peptides |
| JP6319738B2 (ja) * | 2010-07-09 | 2018-05-09 | ステルス ペプチドズ インターナショナル インコーポレイテッド | 虚血／再灌流障害に続くノーリフローの予防又は処置方法 |
| AU2012315586B2 (en) * | 2011-09-29 | 2017-07-20 | Mayo Foundation For Medical Education And Research | Aromatic-cationic peptides and methods for using same |
| EP3009141A1 (en) * | 2011-12-09 | 2016-04-20 | Stealth Peptides International, Inc. | Aromatic-cationic peptides and uses of same |
| JP6317324B2 (ja) * | 2012-03-30 | 2018-04-25 | ステルス ペプチドズ インターナショナル インコーポレイテッド | 神経障害を予防および処置するための方法および組成物 |
| JP2014196281A (ja) * | 2012-08-01 | 2014-10-16 | 健輔 江頭 | 医薬組成物 |
| HK1210953A1 (en) * | 2012-08-02 | 2016-05-13 | Stealth Peptides International, Inc. | Methods for treatment of atherosclerosis |
| AU2013334788A1 (en) * | 2012-10-22 | 2015-06-04 | Henry Ford Health Systems | Methods for reducing risks associated with heart failure and factors associated therewith |
| EP2928562A4 (en) * | 2012-12-06 | 2016-06-22 | Stealth Peptides Int Inc | PEPTIDE THERAPEUTIC PRODUCTS AND METHODS OF USE |
| CN110339339A (zh) | 2013-03-01 | 2019-10-18 | 康德生物医疗技术公司 | 治疗线粒体疾病的方法 |
| EP3626252A1 (en) | 2013-03-01 | 2020-03-25 | Stealth Biotherapeutics Corp | Methods and compositions for the prevention or treatment of barth syndrome |
| WO2014165607A2 (en) * | 2013-04-02 | 2014-10-09 | Stealth Peptides International, Inc. | Aromatic-cationic peptide formulations, compositions and methods of use |
| CA2912386A1 (en) * | 2013-05-14 | 2014-11-20 | Stealth Biotherapeutics Corp | Methods for the prevention or treatment of left ventricular remodeling |
| US20140363391A1 (en) * | 2013-06-06 | 2014-12-11 | Demetris Yannopoulos | System and method for administering poloxamers and anesthetics while performing cpr and minimizing reperfusion injury |
| US10047395B2 (en) | 2013-06-26 | 2018-08-14 | Stealth Biotherapeutics Corp | Methods and compositions for detecting and diagnosing diseases and conditions |
| WO2014210062A1 (en) | 2013-06-26 | 2014-12-31 | Stealth Peptides International, Inc. | Methods for the regulation of matrix metalloproteinase expression |
| WO2014210056A1 (en) * | 2013-06-27 | 2014-12-31 | Stealth Peptides International, Inc. | Peptide therapeutics and methods for using same |
| WO2015023680A1 (en) * | 2013-08-12 | 2015-02-19 | Stealth Peptides International, Inc. | Combination therapy for the treatment of ischemia-reperfusion injury |
| JP6626446B2 (ja) | 2013-12-27 | 2019-12-25 | ステルス バイオセラピューティックス コープ | 薬学的に適切な芳香族カチオン性ペプチド |
| HK1231493A1 (zh) * | 2014-03-03 | 2017-12-22 | Stealth Biotherapeutics Corp | 药学上相关的芳香族阳离子肽 |
| WO2015183984A2 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including tocopherol and uses thereof |
| EP3149035A4 (en) * | 2014-05-28 | 2018-05-16 | Stealth BioTherapeutics Corp | Therapeutic compositions including therapeutic small molecules and uses thereof |
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| WO2016029027A2 (en) | 2014-08-21 | 2016-02-25 | Stealth Biotherapeutics Corp | Methods and compositions for the prevention and treatment of disease |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022511939A (ja) * | 2018-12-18 | 2022-02-01 | ステルス バイオセラピューティクス コーポレーション | ミトコンドリア標的化ペプチド |
| JP7614092B2 (ja) | 2018-12-18 | 2025-01-15 | ステルス バイオセラピューティクス インコーポレイテッド | ミトコンドリア標的化ペプチド |
| JP2022517636A (ja) * | 2019-01-20 | 2022-03-09 | ファーサイト メディカル テクノロジー （シャンハイ） カンパニー リミテッド | シクロスポリン類似体及びその使用 |
| JP7526189B2 (ja) | 2019-01-20 | 2024-07-31 | ファーサイト メディカル テクノロジー （シャンハイ） カンパニー リミテッド | シクロスポリン類似体及びその使用 |
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| EP3210615A1 (en) | 2017-08-30 |
| EP3560508A1 (en) | 2019-10-30 |
| US9561258B2 (en) | 2017-02-07 |
| EP2547352A4 (en) | 2013-10-09 |
| WO2011116007A1 (en) | 2011-09-22 |
| EP2808029A3 (en) | 2015-04-01 |
| EP3040080A1 (en) | 2016-07-06 |
| US20140364370A1 (en) | 2014-12-11 |
| US20170319647A1 (en) | 2017-11-09 |
| US8697657B2 (en) | 2014-04-15 |
| US20130059784A1 (en) | 2013-03-07 |
| EP2808029A2 (en) | 2014-12-03 |
| EP2547352A1 (en) | 2013-01-23 |
| US20200376074A1 (en) | 2020-12-03 |
| US10702577B2 (en) | 2020-07-07 |
| EP3375449A1 (en) | 2018-09-19 |
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