JP2013522311A - シクロスポリンおよび芳香族カチオン性ペプチドを用いた併用療法 - Google Patents
シクロスポリンおよび芳香族カチオン性ペプチドを用いた併用療法 Download PDFInfo
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Hematology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
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| US31394510P | 2010-03-15 | 2010-03-15 | |
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| US37681310P | 2010-08-25 | 2010-08-25 | |
| US61/376,813 | 2010-08-25 | ||
| PCT/US2011/028543 WO2011116007A1 (en) | 2010-03-15 | 2011-03-15 | Combination therapies using cyclosporine and aromatic cationic peptides |
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| JP2013522311A true JP2013522311A (ja) | 2013-06-13 |
| JP2013522311A5 JP2013522311A5 (enExample) | 2014-05-01 |
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| US (4) | US8697657B2 (enExample) |
| EP (6) | EP3560508A1 (enExample) |
| JP (1) | JP2013522311A (enExample) |
| WO (1) | WO2011116007A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022511939A (ja) * | 2018-12-18 | 2022-02-01 | ステルス バイオセラピューティクス コーポレーション | ミトコンドリア標的化ペプチド |
| JP2022517636A (ja) * | 2019-01-20 | 2022-03-09 | ファーサイト メディカル テクノロジー （シャンハイ） カンパニー リミテッド | シクロスポリン類似体及びその使用 |
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|---|---|---|---|---|
| CN103751763A (zh) * | 2009-12-31 | 2014-04-30 | 康肽德生物医药技术有限公司 | 用于预防或治疗血管阻塞损伤的方法 |
| EP3100739A1 (en) * | 2009-12-31 | 2016-12-07 | Stealth Peptides International, Inc. | Methods for performing a coronary artery bypass graft procedure |
| EP3560508A1 (en) * | 2010-03-15 | 2019-10-30 | Stealth Peptides International, Inc. | Combination therapies using cyclosporine and aromatic cationic peptides |
| CN105879008A (zh) * | 2010-07-09 | 2016-08-24 | 康德生物医疗技术公司 | 预防或治疗缺血/再灌注损伤之后无复流的方法 |
| CN107496899A (zh) * | 2011-09-29 | 2017-12-22 | 梅约医学教育与研究基金会 | 芳族阳离子肽和使用它们的方法 |
| EP2788013A4 (en) * | 2011-12-09 | 2015-08-19 | Stealth Peptides Int Inc | AROMATIC-CATIONIC PEPTIDES AND USES THEREOF |
| EP3170506B1 (en) * | 2012-03-30 | 2018-05-16 | Stealth Peptides International, Inc. | Methods and compositions for the prevention and treatment neuropathy |
| JP2014196281A (ja) * | 2012-08-01 | 2014-10-16 | 健輔 江頭 | 医薬組成物 |
| CN104661670A (zh) * | 2012-08-02 | 2015-05-27 | 康肽德生物医药技术有限公司 | 用于治疗动脉粥样硬化的方法 |
| MX2015005102A (es) * | 2012-10-22 | 2016-02-09 | Stealth Peptides Int Inc | Metodos para la reduccion de los riesgos asociados con el insuficiencia cardiaca y factores asociado con el mismo. |
| WO2014088631A1 (en) * | 2012-12-06 | 2014-06-12 | Stealth Peptides International, Inc. | Peptide therapeutics and methods for using same |
| CN117752766A (zh) | 2013-03-01 | 2024-03-26 | 康德生物医疗有限公司 | 治疗线粒体疾病的方法 |
| CN115990242A (zh) | 2013-03-01 | 2023-04-21 | 康德生物医疗有限公司 | 预防或治疗巴斯综合征的方法和组合物 |
| WO2014165607A2 (en) * | 2013-04-02 | 2014-10-09 | Stealth Peptides International, Inc. | Aromatic-cationic peptide formulations, compositions and methods of use |
| CN105579054A (zh) * | 2013-05-14 | 2016-05-11 | 康德生物医疗技术公司 | 预防或治疗左心室重塑的方法 |
| US20140363391A1 (en) * | 2013-06-06 | 2014-12-11 | Demetris Yannopoulos | System and method for administering poloxamers and anesthetics while performing cpr and minimizing reperfusion injury |
| WO2014209905A2 (en) | 2013-06-26 | 2014-12-31 | Stealth Peptides International, Inc. | Methods and compositions for detecting and diagnosing diseases and conditions |
| US9884085B2 (en) | 2013-06-26 | 2018-02-06 | Stealth Biotherapeutics Corp | Methods for the regulation of matrix metalloproteinase expression |
| CA2916492A1 (en) * | 2013-06-27 | 2014-12-31 | Stealth Biotherapeutics Corp | Peptide therapeutics and methods for using same |
| US20160175379A1 (en) * | 2013-08-12 | 2016-06-23 | Stealth Bio Therapeutics Corp | Combination therapy for the treatment of ischemia-reperfusion injury |
| CN112457368A (zh) * | 2013-12-27 | 2021-03-09 | 康德生物医疗技术公司 | 药学相关的芳香族阳离子肽 |
| CA2942143A1 (en) * | 2014-03-03 | 2015-09-11 | Stealth Biotherapeutics Corp | Pharmaceutically relevant aromatic-cationic peptides and methods of generating the same |
| WO2015183984A2 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including tocopherol and uses thereof |
| US20170182117A1 (en) * | 2014-05-28 | 2017-06-29 | Stealth Biotherapeutics Corp | Therapeutic compositions including therapeutic small molecules and uses thereof |
| US10576124B2 (en) * | 2014-05-28 | 2020-03-03 | Stealth Biotherapeutics Corp | Therapeutic compositions including frataxin, lactoferrin, and mitochondrial energy generating enzymes, and uses thereof |
| EP3182989B1 (en) | 2014-08-21 | 2021-04-14 | Stealth Biotherapeutics Corp | Peptide d-arg-2',6'-dmt-lys-phe-nh2 for treating alport syndrome |
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| US11034724B2 (en) | 2017-04-05 | 2021-06-15 | Stealth Biotherapeutics Corp. | Crystalline salt forms of Boc-D-Arg-DMT-Lys-(Boc)-Phe-NH2 |
| WO2018223032A1 (en) * | 2017-06-02 | 2018-12-06 | Stealth Biotherapeutics Corp. | Crystalline salt forms of sbt-20 |
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| JP2013521231A (ja) * | 2010-02-26 | 2013-06-10 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション インコーポレイテッド | ミトコンドリア標的化抗酸化剤は機械的人工呼吸誘発性横隔膜機能障害および骨格筋萎縮を防止する |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022511939A (ja) * | 2018-12-18 | 2022-02-01 | ステルス バイオセラピューティクス コーポレーション | ミトコンドリア標的化ペプチド |
| JP7614092B2 (ja) | 2018-12-18 | 2025-01-15 | ステルス バイオセラピューティクス インコーポレイテッド | ミトコンドリア標的化ペプチド |
| JP2022517636A (ja) * | 2019-01-20 | 2022-03-09 | ファーサイト メディカル テクノロジー （シャンハイ） カンパニー リミテッド | シクロスポリン類似体及びその使用 |
| JP7526189B2 (ja) | 2019-01-20 | 2024-07-31 | ファーサイト メディカル テクノロジー （シャンハイ） カンパニー リミテッド | シクロスポリン類似体及びその使用 |
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| EP2547352A1 (en) | 2013-01-23 |
| EP2808029A2 (en) | 2014-12-03 |
| WO2011116007A1 (en) | 2011-09-22 |
| EP3040080A1 (en) | 2016-07-06 |
| EP2547352A4 (en) | 2013-10-09 |
| US9561258B2 (en) | 2017-02-07 |
| US20140364370A1 (en) | 2014-12-11 |
| EP2808029A3 (en) | 2015-04-01 |
| US10702577B2 (en) | 2020-07-07 |
| US20200376074A1 (en) | 2020-12-03 |
| EP3210615A1 (en) | 2017-08-30 |
| US20170319647A1 (en) | 2017-11-09 |
| US20130059784A1 (en) | 2013-03-07 |
| US8697657B2 (en) | 2014-04-15 |
| EP3560508A1 (en) | 2019-10-30 |
| EP3375449A1 (en) | 2018-09-19 |
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