JP2013521485A5 - - Google Patents

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Publication number
JP2013521485A5
JP2013521485A5 JP2012555389A JP2012555389A JP2013521485A5 JP 2013521485 A5 JP2013521485 A5 JP 2013521485A5 JP 2012555389 A JP2012555389 A JP 2012555389A JP 2012555389 A JP2012555389 A JP 2012555389A JP 2013521485 A5 JP2013521485 A5 JP 2013521485A5
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JP
Japan
Prior art keywords
value
polypeptide
interest
gradient
mobile phase
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JP2012555389A
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English (en)
Japanese (ja)
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JP5992836B2 (ja
JP2013521485A (ja
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Priority claimed from PCT/EP2011/052964 external-priority patent/WO2011107447A1/en
Publication of JP2013521485A publication Critical patent/JP2013521485A/ja
Publication of JP2013521485A5 publication Critical patent/JP2013521485A5/ja
Application granted granted Critical
Publication of JP5992836B2 publication Critical patent/JP5992836B2/ja
Expired - Fee Related legal-status Critical Current
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JP2012555389A 2010-03-01 2011-03-01 ペプチドを精製するための分取rp−hplc法 Expired - Fee Related JP5992836B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP10155023.4 2010-03-01
EP10155023 2010-03-01
US30964210P 2010-03-02 2010-03-02
US61/309,642 2010-03-02
PCT/EP2011/052964 WO2011107447A1 (en) 2010-03-01 2011-03-01 Preparative rp-hplc method for purifying peptides

Publications (3)

Publication Number Publication Date
JP2013521485A JP2013521485A (ja) 2013-06-10
JP2013521485A5 true JP2013521485A5 (OSRAM) 2014-04-17
JP5992836B2 JP5992836B2 (ja) 2016-09-14

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ID=42727392

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012555389A Expired - Fee Related JP5992836B2 (ja) 2010-03-01 2011-03-01 ペプチドを精製するための分取rp−hplc法

Country Status (5)

Country Link
US (1) US9422330B2 (OSRAM)
EP (1) EP2542565A1 (OSRAM)
JP (1) JP5992836B2 (OSRAM)
CN (1) CN102770440A (OSRAM)
WO (1) WO2011107447A1 (OSRAM)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012313045A1 (en) * 2011-09-22 2014-04-10 Hochschule Ostwestfalen-Lippe Method for producing peptide fractions and use thereof
US8921113B2 (en) 2012-12-21 2014-12-30 Dionex Corporation Buffer kit and method of generating a linear pH gradient
EP2950904A1 (en) 2013-01-29 2015-12-09 Neuland Health Sciences Private Limited Purification of organic compounds using surrogate stationary phases on reversed phase columns
MX365465B (es) 2013-03-21 2019-06-04 Sanofi Aventis Deutschland Sintesis de productos peptidicos que contienen imida ciclica.
MX363522B (es) 2013-03-21 2019-03-26 Sanofi Aventis Deutschland Síntesis de productos peptídicos que contienen hidantoína.
EP3046643A4 (en) * 2013-09-20 2017-05-03 Davuluri, Ramamohan Rao Purification of organic compounds by surfactant mediated preparative hplc
CN105223296B (zh) * 2015-10-16 2017-12-05 江苏开元药业有限公司 一类多肽的纯化方法
WO2017162653A1 (en) 2016-03-23 2017-09-28 Bachem Holding Ag Purification of glucagon-like peptide 1 analogs
TWI738260B (zh) 2019-03-25 2021-09-01 台灣神隆股份有限公司 純化利拉魯肽之方法
US12269844B2 (en) 2019-03-25 2025-04-08 Scinopharm Taiwan, Ltd. Process for purifying semaglutide and liraglutide
US11022585B2 (en) 2019-06-09 2021-06-01 Dionex Corporation Methods and systems for optimizing buffer conditions with liquid chromatography
KR20240118914A (ko) 2021-01-20 2024-08-05 바이킹 테라퓨틱스 인코포레이티드 대사 및 간 질환 치료를 위한 조성물 및 방법
CN115703825B (zh) * 2021-08-17 2026-01-02 派格生物医药(杭州)股份有限公司 艾塞那肽变体及其聚乙二醇缀合物的制备方法
KR102873595B1 (ko) 2021-09-15 2025-10-22 바이킹 테라퓨틱스 인코포레이티드 대사 및 간 장애의 치료를 위한 조성물 및 방법
CN114656550A (zh) * 2021-12-28 2022-06-24 深圳翰宇药业股份有限公司 一种利拉鲁肽/索马鲁肽的纯化方法及应用
WO2024147150A1 (en) * 2023-01-02 2024-07-11 Zelle Biotechnology Pvt. Ltd. Chromatographic detection, estimation and separation of amino acids in hydrolysates of monoclonal antibodies

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4028120C2 (de) * 1990-09-05 1996-09-19 Hoechst Ag Verfahren zur Reinigung von Insulin und/oder Insulinderivaten
US5424286A (en) 1993-05-24 1995-06-13 Eng; John Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same
JP2000516912A (ja) 1996-06-05 2000-12-19 ロシュ ダイアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング エキセンジン類似体、それらの製造方法およびそれらを含有する製剤
KR100556067B1 (ko) * 1996-08-30 2006-03-07 노보 노르디스크 에이/에스 지엘피 - 1 유도체
EP1076066A1 (en) 1999-07-12 2001-02-14 Zealand Pharmaceuticals A/S Peptides for lowering blood glucose levels
CN100535007C (zh) * 2003-08-21 2009-09-02 诺沃挪第克公司 胰高血糖素样肽的纯化
ATE437181T1 (de) 2003-08-21 2009-08-15 Novo Nordisk As Reinigung glucagonähnlicher peptide
JP5401097B2 (ja) 2005-12-23 2014-01-29 ノボ・ノルデイスク・エー/エス 分取逆相クロマトグラフィー(rpc)を使用するタンパク質精製
WO2007071767A1 (en) 2005-12-23 2007-06-28 Novo Nordisk Health Care Ag Purification of vitamin k-dependent polypeptides using preparative reverse phase chromatography (rpc)

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