JP2013518579A5 - - Google Patents

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JP2013518579A5
JP2013518579A5 JP2012551704A JP2012551704A JP2013518579A5 JP 2013518579 A5 JP2013518579 A5 JP 2013518579A5 JP 2012551704 A JP2012551704 A JP 2012551704A JP 2012551704 A JP2012551704 A JP 2012551704A JP 2013518579 A5 JP2013518579 A5 JP 2013518579A5
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JP
Japan
Prior art keywords
alk
mutant
nucleic acid
amino acid
protein
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JP2012551704A
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English (en)
Japanese (ja)
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JP2013518579A (ja
JP5937017B2 (ja
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Priority claimed from PCT/IB2011/000382 external-priority patent/WO2011095894A2/en
Publication of JP2013518579A publication Critical patent/JP2013518579A/ja
Publication of JP2013518579A5 publication Critical patent/JP2013518579A5/ja
Application granted granted Critical
Publication of JP5937017B2 publication Critical patent/JP5937017B2/ja
Expired - Fee Related legal-status Critical Current
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JP2012551704A 2010-02-04 2011-02-04 Alk阻害剤に対する自然耐性または獲得耐性を有する癌の同定、評価および治療法 Expired - Fee Related JP5937017B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33746510P 2010-02-04 2010-02-04
US61/337,465 2010-02-04
PCT/IB2011/000382 WO2011095894A2 (en) 2010-02-04 2011-02-04 Identification, assessment, and therapy of cancers with innate or acquired resistance to alk inhibitors

Publications (3)

Publication Number Publication Date
JP2013518579A JP2013518579A (ja) 2013-05-23
JP2013518579A5 true JP2013518579A5 (https=) 2014-04-03
JP5937017B2 JP5937017B2 (ja) 2016-06-22

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ID=44355876

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012551704A Expired - Fee Related JP5937017B2 (ja) 2010-02-04 2011-02-04 Alk阻害剤に対する自然耐性または獲得耐性を有する癌の同定、評価および治療法

Country Status (17)

Country Link
US (1) US9018230B2 (https=)
EP (1) EP2531858B1 (https=)
JP (1) JP5937017B2 (https=)
KR (1) KR101843967B1 (https=)
CN (2) CN102844664A (https=)
AR (1) AR080361A1 (https=)
AU (1) AU2011212165B2 (https=)
BR (1) BR112012019215A2 (https=)
CA (1) CA2786974C (https=)
ES (1) ES2660149T3 (https=)
MX (1) MX336498B (https=)
NZ (1) NZ601606A (https=)
RU (1) RU2589834C2 (https=)
SG (1) SG182766A1 (https=)
TW (1) TWI518325B (https=)
WO (1) WO2011095894A2 (https=)
ZA (1) ZA201205831B (https=)

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US8383793B2 (en) * 2010-04-15 2013-02-26 St. Jude Children's Research Hospital Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
US20120101108A1 (en) * 2010-08-06 2012-04-26 Cell Signaling Technology, Inc. Anaplastic Lymphoma Kinase In Kidney Cancer
JP6205216B2 (ja) * 2012-09-24 2017-09-27 アークレイ株式会社 変異検出用プローブ、変異検出方法、薬効判定方法及び変異検出用キット
US9428812B2 (en) * 2014-04-28 2016-08-30 Insight Genetics, Inc. Kit comprising primers for amplifying ALK kinase domain nucleic acids
DK4074735T3 (da) * 2014-08-28 2025-07-14 Bioatla Inc Betinget aktive kimæriske antigenreceptorer til modificerede t-celler
EP3464625A1 (en) * 2016-06-01 2019-04-10 F. Hoffmann-La Roche AG Novel mutations in anaplastic lymphoma kinase predicting response to alk inhibitor therapy in lung cancer patients
KR101872624B1 (ko) * 2016-12-27 2018-06-28 (주) 바이오인프라생명과학 Alk 표적 치료제에 대한 폐암의 치료 반응성을 예측하는 방법
CN107828823A (zh) * 2017-09-29 2018-03-23 暨南大学 一种评价eml4‑alk抑制剂对肺癌治疗效果的方法
RU2717309C2 (ru) * 2018-08-01 2020-03-20 Общество с ограниченной ответственностью "ОНКОДИАГНОСТИКА АТЛАС" Способ определения микросателлитной нестабильности
BR112020026259A2 (pt) 2018-11-01 2021-07-27 Illumina, Inc. métodos e composições para detecção de variante de linhagem germinativa
CN115997008A (zh) 2020-04-22 2023-04-21 艾欧凡斯生物治疗公司 协调用于患者特异性免疫疗法的细胞的制造的系统和方法
JP2023546359A (ja) 2020-10-06 2023-11-02 アイオバンス バイオセラピューティクス,インコーポレイテッド 腫瘍浸潤リンパ球療法によるnsclc患者の治療
WO2024017352A1 (zh) * 2022-07-22 2024-01-25 四川大学 用于rdaa阳性疾病的诊断和治疗的方法和试剂盒

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