RU2589834C2 - Идентификация, оценка и лечение раковых заболеваний с генетической или приобретенной устойчивостью к ингибиторам alk - Google Patents

Идентификация, оценка и лечение раковых заболеваний с генетической или приобретенной устойчивостью к ингибиторам alk Download PDF

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RU2589834C2
RU2589834C2 RU2012133318/15A RU2012133318A RU2589834C2 RU 2589834 C2 RU2589834 C2 RU 2589834C2 RU 2012133318/15 A RU2012133318/15 A RU 2012133318/15A RU 2012133318 A RU2012133318 A RU 2012133318A RU 2589834 C2 RU2589834 C2 RU 2589834C2
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alk
cancer
marker
cells
mutant
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Хироюки МАНО
Янг Л. ЧОЙ
Манабу СОДА
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Джичи Медикал Юниверсити
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2012133318/15A 2010-02-04 2011-02-04 Идентификация, оценка и лечение раковых заболеваний с генетической или приобретенной устойчивостью к ингибиторам alk RU2589834C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33746510P 2010-02-04 2010-02-04
US61/337,465 2010-02-04
PCT/IB2011/000382 WO2011095894A2 (en) 2010-02-04 2011-02-04 Identification, assessment, and therapy of cancers with innate or acquired resistance to alk inhibitors

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RU2012133318A RU2012133318A (ru) 2014-03-10
RU2589834C2 true RU2589834C2 (ru) 2016-07-10

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US (1) US9018230B2 (https=)
EP (1) EP2531858B1 (https=)
JP (1) JP5937017B2 (https=)
KR (1) KR101843967B1 (https=)
CN (2) CN102844664A (https=)
AR (1) AR080361A1 (https=)
AU (1) AU2011212165B2 (https=)
BR (1) BR112012019215A2 (https=)
CA (1) CA2786974C (https=)
ES (1) ES2660149T3 (https=)
MX (1) MX336498B (https=)
NZ (1) NZ601606A (https=)
RU (1) RU2589834C2 (https=)
SG (1) SG182766A1 (https=)
TW (1) TWI518325B (https=)
WO (1) WO2011095894A2 (https=)
ZA (1) ZA201205831B (https=)

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RU2717309C2 (ru) * 2018-08-01 2020-03-20 Общество с ограниченной ответственностью "ОНКОДИАГНОСТИКА АТЛАС" Способ определения микросателлитной нестабильности
RU2764074C2 (ru) * 2014-08-28 2022-01-13 Байоатла, Ллк Условно активные химерные антигенные рецепторы для модифицированных т-клеток
RU2813655C2 (ru) * 2018-11-01 2024-02-14 Иллюмина, Инк. Способы и композиции для обнаружения соматического варианта
US12417819B2 (en) 2018-11-01 2025-09-16 Illumina, Inc. Methods and compositions for germline variant detection

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US8383793B2 (en) * 2010-04-15 2013-02-26 St. Jude Children's Research Hospital Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
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JP6205216B2 (ja) * 2012-09-24 2017-09-27 アークレイ株式会社 変異検出用プローブ、変異検出方法、薬効判定方法及び変異検出用キット
US9428812B2 (en) * 2014-04-28 2016-08-30 Insight Genetics, Inc. Kit comprising primers for amplifying ALK kinase domain nucleic acids
EP3464625A1 (en) * 2016-06-01 2019-04-10 F. Hoffmann-La Roche AG Novel mutations in anaplastic lymphoma kinase predicting response to alk inhibitor therapy in lung cancer patients
KR101872624B1 (ko) * 2016-12-27 2018-06-28 (주) 바이오인프라생명과학 Alk 표적 치료제에 대한 폐암의 치료 반응성을 예측하는 방법
CN107828823A (zh) * 2017-09-29 2018-03-23 暨南大学 一种评价eml4‑alk抑制剂对肺癌治疗效果的方法
CN115997008A (zh) 2020-04-22 2023-04-21 艾欧凡斯生物治疗公司 协调用于患者特异性免疫疗法的细胞的制造的系统和方法
JP2023546359A (ja) 2020-10-06 2023-11-02 アイオバンス バイオセラピューティクス，インコーポレイテッド 腫瘍浸潤リンパ球療法によるｎｓｃｌｃ患者の治療
WO2024017352A1 (zh) * 2022-07-22 2024-01-25 四川大学 用于rdaa阳性疾病的诊断和治疗的方法和试剂盒

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