JP2013518396A5 - - Google Patents

Download PDF

Info

Publication number
JP2013518396A5
JP2013518396A5 JP2012551316A JP2012551316A JP2013518396A5 JP 2013518396 A5 JP2013518396 A5 JP 2013518396A5 JP 2012551316 A JP2012551316 A JP 2012551316A JP 2012551316 A JP2012551316 A JP 2012551316A JP 2013518396 A5 JP2013518396 A5 JP 2013518396A5
Authority
JP
Japan
Prior art keywords
ion
region
ions
pressure
dms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012551316A
Other languages
English (en)
Japanese (ja)
Other versions
JP5985989B2 (ja
JP2013518396A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/022905 external-priority patent/WO2011094529A2/en
Publication of JP2013518396A publication Critical patent/JP2013518396A/ja
Publication of JP2013518396A5 publication Critical patent/JP2013518396A5/ja
Application granted granted Critical
Publication of JP5985989B2 publication Critical patent/JP5985989B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012551316A 2010-01-28 2011-01-28 低圧微分移動度分光計を備えた質量分析システム Expired - Fee Related JP5985989B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29908610P 2010-01-28 2010-01-28
US61/299,086 2010-01-28
PCT/US2011/022905 WO2011094529A2 (en) 2010-01-28 2011-01-28 Mass analysis system with low pressure differential mobility spectrometer

Publications (3)

Publication Number Publication Date
JP2013518396A JP2013518396A (ja) 2013-05-20
JP2013518396A5 true JP2013518396A5 (https=) 2014-03-13
JP5985989B2 JP5985989B2 (ja) 2016-09-06

Family

ID=44309254

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012551316A Expired - Fee Related JP5985989B2 (ja) 2010-01-28 2011-01-28 低圧微分移動度分光計を備えた質量分析システム

Country Status (5)

Country Link
US (2) US20110183431A1 (https=)
EP (1) EP2529387B1 (https=)
JP (1) JP5985989B2 (https=)
CA (1) CA2788455C (https=)
WO (1) WO2011094529A2 (https=)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010081830A1 (en) * 2009-01-14 2010-07-22 Sociedad Europea De Análisis Diferencial De Movilidad, S.L. Improved ionizer for vapor analysis decoupling the ionization region from the analyzer
US8941054B2 (en) * 2011-04-26 2015-01-27 Bruker Daltonik Gmbh Selective ion mobility spectrometer formed from two consecutive mass selective filters
WO2012167254A1 (en) * 2011-06-03 2012-12-06 Dh Technologies Development Pte. Ltd. Method and system for reducing interferences in the spectrometric analysis of steroids
WO2013061141A1 (en) * 2011-10-26 2013-05-02 Dh Technologies Development Pte. Ltd. Apparatus and method for fractionation
GB2509412B (en) 2012-02-21 2016-06-01 Thermo Fisher Scient (Bremen) Gmbh Apparatus and methods for ion mobility spectrometry
WO2013152344A1 (en) * 2012-04-06 2013-10-10 Implant Sciences Corporation Selective ionization using high frequency filtering of reactive ions
WO2013171569A1 (en) * 2012-05-18 2013-11-21 Dh Technologies Development Pte. Ltd. Reducing interferences in isobaric tag-based quantification
WO2013171556A1 (en) * 2012-05-18 2013-11-21 Dh Technologies Development Pte. Ltd. Modulation of instrument resolution dependant upon the complexity of a previous scan
GB2508574B (en) * 2012-06-24 2014-12-17 Fasmatech Science And Technology Sa Improvements in and relating to the control of ions
GB2517670B (en) * 2013-03-15 2020-04-29 Smiths Detection Watford Ltd Ion modification
US9564302B2 (en) * 2013-06-21 2017-02-07 Dh Technologies Development Pte. Ltd. Contamination filter for mass spectrometer
EP3032571A4 (en) * 2013-08-08 2016-12-21 Shimadzu Corp TRIPLE QUADRUPOL MASS SPECTROMETER
US9390898B1 (en) 2013-08-30 2016-07-12 Leidos, Inc. System and method for fusing chemical detectors
US9057699B2 (en) 2013-11-21 2015-06-16 Hamilton Sundstrand Corporation High temperature differential ion mobility spectroscopy
EP3086882B1 (en) 2013-12-24 2021-05-26 Waters Technologies Corporation Atmospheric interface for electrically grounded electrospray
GB2529330B (en) * 2013-12-24 2016-07-06 Waters Technologies Corp Reflectron
EP3092484A4 (en) * 2013-12-31 2017-08-23 DH Technologies Development PTE. Ltd. Vacuum dms with high efficiency ion guides
JP6549130B2 (ja) * 2013-12-31 2019-07-24 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 微分移動度分光計のための噴射注入器入口
US10371665B2 (en) * 2014-06-06 2019-08-06 Micromass Uk Limited Mobility selective attenuation
GB201410369D0 (en) * 2014-06-11 2014-07-23 Micromass Ltd Monitoring IMS environment for improved CCS accuracy and precision
WO2015189545A1 (en) * 2014-06-11 2015-12-17 Micromass Uk Limited Ion mobility spectrometry data directed acquisition
EP3155414B8 (en) 2014-06-11 2021-12-01 Micromass UK Limited Monitoring ion mobility spectrometry environment for improved collision cross section accuracy and precision
US9704700B2 (en) * 2014-06-16 2017-07-11 Purdue Research Foundation Sample analysis systems and methods of use thereof
WO2016020788A1 (en) * 2014-08-05 2016-02-11 Dh Technologies Development Pte. Ltd. Methods for distinguishing dioleinates of aged and non-aged olive oil
GB2531285B (en) 2014-10-14 2017-07-26 Smiths Detection-Watford Ltd Ion mobility spectrometer with ion modification
EP3210234A4 (en) * 2014-10-22 2018-06-27 DH Technologies Development Pte. Ltd. Methods and systems for cross-talk elimination in continuous beam mobility-based spectrometers
WO2016108126A1 (en) * 2014-12-31 2016-07-07 Dh Technologies Development Pte. Ltd. Differential mobility spectrometry method
WO2016125120A1 (en) * 2015-02-06 2016-08-11 Dh Technologies Development Pte. Ltd. Lipid screening platform allowing a complete solution for lipidomics research
CN104637777B (zh) * 2015-02-16 2017-05-17 江苏天瑞仪器股份有限公司 一种质谱仪反吹气结构
CN104833761B (zh) * 2015-06-01 2017-04-26 华质泰科生物技术（北京）有限公司 一种快速分析样品中的糖类化合物的方法
US9607817B1 (en) 2015-09-11 2017-03-28 Thermo Finnigan Llc Systems and methods for ion separation
US10770279B2 (en) * 2015-11-27 2020-09-08 Shimadzu Corporation Ion transfer apparatus
US10541122B2 (en) 2017-06-13 2020-01-21 Mks Instruments, Inc. Robust ion source
US11424114B2 (en) * 2017-11-28 2022-08-23 Dh Technologies Development Pte. Ltd. Predicting molecular collision cross-section using differential mobility spectrometry
CN111758146A (zh) * 2018-01-17 2020-10-09 Dh科技发展私人贸易有限公司 用于提高msms置信度的dm-swath获取
US10467362B2 (en) * 2018-01-19 2019-11-05 Nikolai Kislov Analytical tools and methods for modeling transport processes in fluids
US11874251B2 (en) * 2018-02-13 2024-01-16 Jp Scientific Limited Ion mobility spectrometer and method of analyzing ions
WO2019236139A1 (en) * 2018-06-04 2019-12-12 The Trustees Of Indiana University Interface for transporting ions from an atmospheric pressure environment to a low pressure environment
US10663428B2 (en) 2018-06-29 2020-05-26 Thermo Finnigan Llc Systems and methods for ion separation using IMS-MS with multiple ion exits
US10663430B2 (en) * 2018-08-08 2020-05-26 Thermo Finnigan Llc Quantitation throughput enhancement by differential mobility based pre-separation
CN109065435A (zh) * 2018-08-28 2018-12-21 山东省分析测试中心 一种微电离喷雾离子源差分离子迁移谱及其应用方法
CN114365259A (zh) * 2019-08-21 2022-04-15 Dh科技发展私人贸易有限公司 用于质谱系统中的热解离的设备和方法
US11293898B2 (en) 2020-02-06 2022-04-05 Thermo Finnigan Llc Duty cycle improvement for a mass spectrometer using ion mobility separation
GB202004961D0 (en) 2020-04-03 2020-05-20 Micromass Ltd De-clustering guide
GB2623465B (en) * 2020-05-29 2024-11-20 Bruker Scient Llc Electrospray ion source for spectrometry using inductively heated gas
US11273465B1 (en) * 2020-09-17 2022-03-15 Desaraju Subrahmanyam Tunable electrostatic ion and fluid flow generator and electroacoustic transducer
US20220397552A1 (en) * 2021-06-10 2022-12-15 GP Ionics LLC Molecular identification using field induced fragmentation spectra by reactive stage tandem differential mobility spectrometry
US20240282564A1 (en) * 2021-06-22 2024-08-22 Dh Technologies Development Pte. Ltd. Automated systems and methods for separating compounds
US12235239B2 (en) 2022-04-05 2025-02-25 Thermo Finnigan Llc Ion mobility enhanced qualitative and quantitative methods
EP4684204A1 (en) * 2023-03-23 2026-01-28 DH Technologies Development Pte. Ltd. Method and system for introducing modifier into a curtain gas stream for a differential mobility spectrometer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5432343A (en) * 1993-06-03 1995-07-11 Gulcicek; Erol E. Ion focusing lensing system for a mass spectrometer interfaced to an atmospheric pressure ion source
US7164122B2 (en) * 2000-02-29 2007-01-16 Ionwerks, Inc. Ion mobility spectrometer
EP1273029B8 (en) * 2000-03-14 2006-01-11 National Research Council Canada Faims apparatus and method with laser-based ionization source
EP1690074A2 (en) * 2003-11-25 2006-08-16 Sionex Corporation Mobility based apparatus and methods using dispersion characteristics, sample fragmentation, and/or pressure control to improve analysis of a sample
GB0503010D0 (en) * 2005-02-14 2005-03-16 Micromass Ltd Mass spectrometer
US7528365B2 (en) * 2006-02-07 2009-05-05 Applera Corporation Chemical noise reduction for mass spectrometry
US7812305B2 (en) * 2006-06-29 2010-10-12 Sionex Corporation Tandem differential mobility spectrometers and mass spectrometer for enhanced analysis
US7598488B2 (en) * 2006-09-20 2009-10-06 Park Melvin A Apparatus and method for field asymmetric ion mobility spectrometry combined with mass spectrometry
US7863562B2 (en) * 2007-06-22 2011-01-04 Shimadzu Corporation Method and apparatus for digital differential ion mobility separation
CA2720244C (en) * 2008-05-30 2018-02-27 Dh Technologies Development Pte. Ltd. Method and system for vacuum driven differential mobility spectrometer/mass spectrometer interface with adjustable resolution and selectivity

Similar Documents

Publication Publication Date Title
JP2013518396A5 (https=)
CA2788455C (en) Mass analysis system with low pressure differential mobility spectrometer
US8513600B2 (en) Method and system for vacuum driven mass spectrometer interface with adjustable resolution and selectivity
EP2281297B1 (en) Method and system for vacuum driven differential mobility spectrometer/mass spectrometer interface with adjustable resolution and selectivity
JP7210536B2 (ja) 電子イオン化源からのイオンの移動
JP2010062152A5 (https=)
EP2808888B1 (en) Mass analysis device
US20080203292A1 (en) Mass spectrometer
CN105632870B (zh) 一种用于质谱的大气压化学电离源
ITTO20140088U1 (it) Sorgente di ioni magnetica assiale e relativi metodi di ionizzazione.
CN101405828A (zh) 离子化装置
RU2017114148A (ru) Способ и устройство
CN105916571B (zh) 用于差分迁移谱仪的射流注射器入口
CN105874331A (zh) 使用高效离子导向器的真空dms
EP2993469A1 (en) Method for analysis of sample and apparatus therefor
JP2009259465A (ja) イオンフィルタ、質量分析システムおよびイオン移動度分光計
EP2795663B1 (en) Improvements in or relating to mass spectrometry
CN117120834A (zh) 传输气流量大于10升/分钟的差分迁移率谱仪/质谱仪接口
JP2015505970A (ja) 周期場微分型電気移動度分析装置
CN202167455U (zh) 一种基于离子漏斗的质子转移离子源装置
CN102280351A (zh) 一种基于离子漏斗的质子转移离子源装置
CN114171369B (zh) 一种多离子源质谱仪器
JP2017523416A (ja) 試料の化学イオン化方法と装置