JP2013518124A - Ｃ型肝炎ウイルス感染の処置のための治療法 - Google Patents

Ｃ型肝炎ウイルス感染の処置のための治療法 Download PDF

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Publication number
JP2013518124A
JP2013518124A JP2012551302A JP2012551302A JP2013518124A JP 2013518124 A JP2013518124 A JP 2013518124A JP 2012551302 A JP2012551302 A JP 2012551302A JP 2012551302 A JP2012551302 A JP 2012551302A JP 2013518124 A JP2013518124 A JP 2013518124A
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Japan
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administered
weeks
administration
interferon
pegylated interferon
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Pending
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JP2012551302A
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Japanese (ja)
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JP2013518124A5 (https=
Inventor
マリア・ロザリオ
ナタリー・ショーレ
シェリー・ジョージ
タラ・リン・キーファー
マーガレット・ジェイムズ・コジエル
オリヴィエ・ニコラ
ルイーズ・プルー
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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Application filed by Vertex Pharmaceuticals Inc filed Critical Vertex Pharmaceuticals Inc
Publication of JP2013518124A publication Critical patent/JP2013518124A/ja
Publication of JP2013518124A5 publication Critical patent/JP2013518124A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2012551302A 2010-01-29 2011-01-28 Ｃ型肝炎ウイルス感染の処置のための治療法 Pending JP2013518124A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US29964310P 2010-01-29 2010-01-29
US61/299,643 2010-01-29
US30850610P 2010-02-26 2010-02-26
US61/308,506 2010-02-26
US30911710P 2010-03-01 2010-03-01
US61/309,117 2010-03-01
US32439510P 2010-04-15 2010-04-15
US61/324,395 2010-04-15
PCT/US2011/022854 WO2011094489A1 (en) 2010-01-29 2011-01-28 Therapies for treating hepatitis c virus infection

Publications (2)

Publication Number Publication Date
JP2013518124A true JP2013518124A (ja) 2013-05-20
JP2013518124A5 JP2013518124A5 (https=) 2014-03-20

Family

ID=43901208

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012551302A Pending JP2013518124A (ja) 2010-01-29 2011-01-28 Ｃ型肝炎ウイルス感染の処置のための治療法

Country Status (14)

Country Link
US (1) US20130034522A1 (https=)
EP (1) EP2528605A1 (https=)
JP (1) JP2013518124A (https=)
KR (1) KR20120139699A (https=)
CN (1) CN102844030A (https=)
AU (1) AU2011210795A1 (https=)
CA (1) CA2788348A1 (https=)
IL (1) IL220937A0 (https=)
MX (1) MX2012008652A (https=)
RU (1) RU2012136824A (https=)
SG (1) SG182589A1 (https=)
TW (1) TW201130502A (https=)
WO (1) WO2011094489A1 (https=)
ZA (1) ZA201205547B (https=)

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NZ607996A (en) 2010-09-22 2014-07-25 Alios Biopharma Inc Substituted nucleotide analogs
DE202012012955U1 (de) * 2011-10-21 2014-07-14 Abbvie Inc. Eine Kombination aus mindestens zwei direkt wirkenden antiviralen Wirkstoffen (DAAs) für die Verwendung zur Behandlung von HCV
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
EP2583677A3 (en) 2011-10-21 2013-07-03 Abbvie Inc. Methods for treating HCV comprising at least two direct acting antiviral agent, ribavirin but not interferon.
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
CA2860234A1 (en) 2011-12-22 2013-06-27 Alios Biopharma, Inc. Substituted phosphorothioate nucleotide analogs
WO2013142159A1 (en) * 2012-03-21 2013-09-26 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog
HK1206362A1 (zh) 2012-03-21 2016-01-08 Alios Biopharma, Inc. 硫代氨基磷酸酯核苷酸前藥的固體形式
WO2013142157A1 (en) 2012-03-22 2013-09-26 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog
EA201892448A1 (ru) 2016-04-28 2019-06-28 Эмори Юниверсити Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения

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Also Published As

Publication number Publication date
KR20120139699A (ko) 2012-12-27
WO2011094489A1 (en) 2011-08-04
TW201130502A (en) 2011-09-16
AU2011210795A1 (en) 2012-08-02
US20130034522A1 (en) 2013-02-07
IL220937A0 (en) 2012-09-24
RU2012136824A (ru) 2014-03-10
MX2012008652A (es) 2012-08-23
ZA201205547B (en) 2013-04-24
EP2528605A1 (en) 2012-12-05
CN102844030A (zh) 2012-12-26
CA2788348A1 (en) 2011-08-04
SG182589A1 (en) 2012-08-30

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