JP2013518107A5 - - Google Patents

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Publication number
JP2013518107A5
JP2013518107A5 JP2012551213A JP2012551213A JP2013518107A5 JP 2013518107 A5 JP2013518107 A5 JP 2013518107A5 JP 2012551213 A JP2012551213 A JP 2012551213A JP 2012551213 A JP2012551213 A JP 2012551213A JP 2013518107 A5 JP2013518107 A5 JP 2013518107A5
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JP
Japan
Prior art keywords
acceptable salt
pharmaceutically acceptable
combination
abacavir
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012551213A
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English (en)
Japanese (ja)
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JP2013518107A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/022219 external-priority patent/WO2011094150A1/en
Publication of JP2013518107A publication Critical patent/JP2013518107A/ja
Publication of JP2013518107A5 publication Critical patent/JP2013518107A5/ja
Pending legal-status Critical Current

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JP2012551213A 2010-01-27 2011-01-24 抗ウイルス療法 Pending JP2013518107A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29858910P 2010-01-27 2010-01-27
US61/298,589 2010-01-27
PCT/US2011/022219 WO2011094150A1 (en) 2010-01-27 2011-01-24 Antiviral therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016015242A Division JP2016145204A (ja) 2010-01-27 2016-01-29 抗ウイルス療法

Publications (2)

Publication Number Publication Date
JP2013518107A JP2013518107A (ja) 2013-05-20
JP2013518107A5 true JP2013518107A5 (US07585860-20090908-C00112.png) 2014-03-13

Family

ID=44319704

Family Applications (8)

Application Number Title Priority Date Filing Date
JP2012551213A Pending JP2013518107A (ja) 2010-01-27 2011-01-24 抗ウイルス療法
JP2016015242A Pending JP2016145204A (ja) 2010-01-27 2016-01-29 抗ウイルス療法
JP2016161610A Active JP6268386B2 (ja) 2010-01-27 2016-08-22 抗ウイルス療法
JP2018072861A Pending JP2018127473A (ja) 2010-01-27 2018-04-05 抗ウイルス療法
JP2019106635A Pending JP2019167371A (ja) 2010-01-27 2019-06-07 抗ウイルス療法
JP2021030306A Pending JP2021091705A (ja) 2010-01-27 2021-02-26 抗ウイルス療法
JP2022032464A Pending JP2022071126A (ja) 2010-01-27 2022-03-03 抗ウイルス療法
JP2023060638A Pending JP2023085431A (ja) 2010-01-27 2023-04-04 抗ウイルス療法

Family Applications After (7)

Application Number Title Priority Date Filing Date
JP2016015242A Pending JP2016145204A (ja) 2010-01-27 2016-01-29 抗ウイルス療法
JP2016161610A Active JP6268386B2 (ja) 2010-01-27 2016-08-22 抗ウイルス療法
JP2018072861A Pending JP2018127473A (ja) 2010-01-27 2018-04-05 抗ウイルス療法
JP2019106635A Pending JP2019167371A (ja) 2010-01-27 2019-06-07 抗ウイルス療法
JP2021030306A Pending JP2021091705A (ja) 2010-01-27 2021-02-26 抗ウイルス療法
JP2022032464A Pending JP2022071126A (ja) 2010-01-27 2022-03-03 抗ウイルス療法
JP2023060638A Pending JP2023085431A (ja) 2010-01-27 2023-04-04 抗ウイルス療法

Country Status (45)

Country Link
US (12) US20120295898A1 (US07585860-20090908-C00112.png)
EP (6) EP3351249A1 (US07585860-20090908-C00112.png)
JP (8) JP2013518107A (US07585860-20090908-C00112.png)
KR (4) KR101883750B1 (US07585860-20090908-C00112.png)
CN (2) CN102791129B (US07585860-20090908-C00112.png)
AP (1) AP3551A (US07585860-20090908-C00112.png)
AU (1) AU2011209788C1 (US07585860-20090908-C00112.png)
BR (1) BR112012018670A2 (US07585860-20090908-C00112.png)
CA (4) CA3003988C (US07585860-20090908-C00112.png)
CL (1) CL2012002080A1 (US07585860-20090908-C00112.png)
CO (1) CO6602152A2 (US07585860-20090908-C00112.png)
CR (1) CR20120423A (US07585860-20090908-C00112.png)
CY (4) CY1116509T1 (US07585860-20090908-C00112.png)
DK (4) DK3127542T3 (US07585860-20090908-C00112.png)
DO (2) DOP2012000205A (US07585860-20090908-C00112.png)
EA (4) EA032868B1 (US07585860-20090908-C00112.png)
EC (1) ECSP12012106A (US07585860-20090908-C00112.png)
ES (4) ES2688925T3 (US07585860-20090908-C00112.png)
FI (2) FI3494972T3 (US07585860-20090908-C00112.png)
FR (1) FR18C1043I2 (US07585860-20090908-C00112.png)
HK (3) HK1209629A1 (US07585860-20090908-C00112.png)
HR (4) HRP20240168T1 (US07585860-20090908-C00112.png)
HU (4) HUE037812T2 (US07585860-20090908-C00112.png)
IL (5) IL221007A (US07585860-20090908-C00112.png)
LT (4) LT2932970T (US07585860-20090908-C00112.png)
LU (1) LUC00090I2 (US07585860-20090908-C00112.png)
MA (1) MA34002B1 (US07585860-20090908-C00112.png)
ME (2) ME03058B (US07585860-20090908-C00112.png)
MX (4) MX367937B (US07585860-20090908-C00112.png)
MY (1) MY188334A (US07585860-20090908-C00112.png)
NO (2) NO2932970T3 (US07585860-20090908-C00112.png)
NZ (4) NZ601319A (US07585860-20090908-C00112.png)
PE (2) PE20160180A1 (US07585860-20090908-C00112.png)
PH (2) PH12016500195B1 (US07585860-20090908-C00112.png)
PL (4) PL3494972T3 (US07585860-20090908-C00112.png)
PT (4) PT3494972T (US07585860-20090908-C00112.png)
RS (4) RS65183B1 (US07585860-20090908-C00112.png)
SG (3) SG10201509476RA (US07585860-20090908-C00112.png)
SI (4) SI2932970T1 (US07585860-20090908-C00112.png)
SM (1) SMT201500177B (US07585860-20090908-C00112.png)
TN (1) TN2012000376A1 (US07585860-20090908-C00112.png)
TR (1) TR201807704T4 (US07585860-20090908-C00112.png)
UA (1) UA105556C2 (US07585860-20090908-C00112.png)
WO (1) WO2011094150A1 (US07585860-20090908-C00112.png)
ZA (1) ZA201205586B (US07585860-20090908-C00112.png)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101883750B1 (ko) 2010-01-27 2018-07-31 비이브 헬쓰케어 컴퍼니 항바이러스 치료
JP2015534973A (ja) 2012-10-23 2015-12-07 シプラ・リミテッド 抗レトロウイルス医薬組成物
SG11201504857SA (en) 2012-12-21 2015-07-30 Gilead Sciences Inc Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
EP2767272A1 (en) * 2013-02-18 2014-08-20 Ratiopharm GmbH Solid pharmaceutical dosage form of dolutegravir
WO2014125124A1 (en) * 2013-02-18 2014-08-21 Ratiopharm Gmbh Solid pharmaceutical dosage form of dolutegravir
CA2916993C (en) 2013-07-12 2019-01-15 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
NO2865735T3 (US07585860-20090908-C00112.png) 2013-07-12 2018-07-21
SG11201602217XA (en) 2013-09-27 2016-04-28 Merck Sharp & Dohme Substituted quinolizine derivatives useful as hiv integrase inhibitors
WO2015140569A1 (en) 2014-03-20 2015-09-24 Cipla Limited Pharmaceutical composition
WO2015187998A2 (en) * 2014-06-04 2015-12-10 Sanford-Burnham Medical Research Institute Use of inhibitor of apoptosis protein (iap) antagonists in hiv therapy
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
NO2717902T3 (US07585860-20090908-C00112.png) 2014-06-20 2018-06-23
TWI677489B (zh) 2014-06-20 2019-11-21 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
US10189860B2 (en) 2014-07-29 2019-01-29 Lek Pharmaceuticals D.D. Hydrates of dolutegravir sodium
TWI695003B (zh) 2014-12-23 2020-06-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
PL3277691T3 (pl) 2015-04-02 2019-07-31 Gilead Sciences, Inc. Policykliczne związki karbamoilopirydonowe i ich zastosowanie farmaceutyczne
WO2017029226A1 (en) 2015-08-14 2017-02-23 Sandoz Ag Solid pharmaceutical composition of abacavir, lamivudine, and efavirenz
WO2017205585A1 (en) * 2016-05-27 2017-11-30 Viiv Healthcare Company Combinations and uses treatments thereof
WO2018028841A1 (en) * 2016-08-12 2018-02-15 Sandoz Ag Solid pharmaceutical composition of abacavir, lamivudine, and efavirenz
WO2018042332A1 (en) * 2016-08-31 2018-03-08 Glaxosmithkline Intellectual Property (No.2) Limited Combinations and uses and treatments thereof
EP3655106A4 (en) * 2017-07-18 2021-04-21 VIIV Healthcare Company COMBINED INGREDIENTS THERAPY
WO2019016760A1 (en) * 2017-07-21 2019-01-24 Viiv Healthcare Company REGIMES AND PREPARATIONS FOR THE TREATMENT OF HIV INFECTIONS AND AIDS
MX2020000790A (es) 2017-07-21 2020-11-11 Viiv Healthcare Co Pautas para el tratamiento de infecciones por el vih y sida.
KR20200070246A (ko) * 2017-10-13 2020-06-17 비이브 헬쓰케어 컴퍼니 이중층 제약 정제 제제
PL3938047T3 (pl) 2019-03-22 2022-11-07 Gilead Sciences, Inc. Zmostkowane tricykliczne związki karbamoilopirydonowe i ich zastosowanie farmaceutyczne
BR112022013452A2 (pt) * 2020-01-09 2022-09-13 Univ Washington Combinações de agentes terapêuticos de ação prolongada e métodos das mesmas
WO2021173522A1 (en) 2020-02-24 2021-09-02 Gilead Sciences, Inc. Tetracyclic compounds for treating hiv infection
PT4196479T (pt) 2021-01-19 2024-01-03 Gilead Sciences Inc Compostos de piridotriazinas substituídos e suas utilizações
WO2023164293A1 (en) * 2022-02-28 2023-08-31 Jericho Sciences, Llc Methods for viral infections

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7119202B1 (en) 1989-02-08 2006-10-10 Glaxo Wellcome Inc. Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties
US5047407A (en) 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
GB8815265D0 (en) 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
GB9009861D0 (en) 1990-05-02 1990-06-27 Glaxo Group Ltd Chemical compounds
ZA923641B (en) 1991-05-21 1993-02-24 Iaf Biochem Int Processes for the diastereoselective synthesis of nucleosides
GB9111902D0 (en) 1991-06-03 1991-07-24 Glaxo Group Ltd Chemical compounds
GB9204015D0 (en) 1992-02-25 1992-04-08 Wellcome Found Therapeutic nucleosides
IL106507A (en) 1992-08-07 1997-11-20 Merck & Co Inc Pharmaceutical compositions containing benzoxazinones and some novel compounds of this type
US5665720A (en) 1992-08-07 1997-09-09 Merck & Co., Inc. Benzoxazinones as inhibitors of HIV reverse transcriptase
GB9402161D0 (en) 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
IL113432A (en) 1994-04-23 2000-11-21 Glaxo Group Ltd Process for the diastereoselective synthesis of nucleoside analogues
UA49803C2 (uk) 1994-06-03 2002-10-15 Дж.Д. Сьорль Енд Ко Спосіб лікування ретровірусних інфекцій
MY115461A (en) 1995-03-30 2003-06-30 Wellcome Found Synergistic combinations of zidovudine, 1592u89 and 3tc
US5914332A (en) 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
US5849911A (en) 1996-04-22 1998-12-15 Novartis Finance Corporation Antivirally active heterocyclic azahexane derivatives
JP2000515852A (ja) * 1996-06-25 2000-11-28 グラクソ、グループ、リミテッド Hivの治療に使用するためのvx478、ジドブジン、ftcおよび/または3tcを含んでなる組合わせ
US5922695A (en) 1996-07-26 1999-07-13 Gilead Sciences, Inc. Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability
US5965729A (en) 1997-02-05 1999-10-12 Merck & Co., Inc. Process for the crystallization of a reverse transcriptase inhibitor using an anti-solvent
GB9709945D0 (en) 1997-05-17 1997-07-09 Glaxo Group Ltd A novel salt
US5935946A (en) 1997-07-25 1999-08-10 Gilead Sciences, Inc. Nucleotide analog composition and synthesis method
GB9717928D0 (en) 1997-08-22 1997-10-29 Glaxo Group Ltd Process for the enatioselective hydrolysis of n-derivatised lactams
GB9721780D0 (en) 1997-10-14 1997-12-10 Glaxo Group Ltd Process for the synthesis of chloropurine intermediates
US6436989B1 (en) 1997-12-24 2002-08-20 Vertex Pharmaceuticals, Incorporated Prodrugs of aspartyl protease inhibitors
US6087383A (en) 1998-01-20 2000-07-11 Bristol-Myers Squibb Company Bisulfate salt of HIV protease inhibitor
GB9805898D0 (en) 1998-03-20 1998-05-13 Glaxo Group Ltd Process for the sythesis of hiv protease inhibitors
EP1063888A1 (en) 1998-03-27 2001-01-03 The Regents of the University of California Novel hiv integrase inhibitors and hiv therapy based on drug combinations including integrase inhibitors
UA72207C2 (uk) 1998-04-07 2005-02-15 Брістол- Майєрс Сквібб Фарма Компані Фармацевтична композиція ефавіренцу з добавкою дезінтегруючих агентів у вигляді швидкорозчинних капсул або таблеток та спосіб її виготовлення
GB9809213D0 (en) * 1998-04-29 1998-07-01 Glaxo Group Ltd Pharmaceutical compositions
GB9815567D0 (en) 1998-07-18 1998-09-16 Glaxo Group Ltd Antiviral compound
PL211860B1 (pl) 2000-01-31 2012-07-31 Cook Biotech Inc Zespół zastawki stentu
ME00558A (en) 2001-04-10 2011-12-20 Pyrazole derivatives for treating hiv
JO3429B1 (ar) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
US7638522B2 (en) * 2001-08-13 2009-12-29 Janssen Pharmaceutica N.V. Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
TW200403061A (en) * 2002-06-04 2004-03-01 Glaxo Group Ltd Pharmaceutical compositions
US20060084627A1 (en) 2002-06-27 2006-04-20 Medivir Ab Synergistic interaction of abacavir and alovudine
DK1583542T3 (da) * 2003-01-14 2008-09-22 Gilead Sciences Inc Sammensætninger og fremgangsmåder til antiviral kombinationsterapi
TW200510425A (en) 2003-08-13 2005-03-16 Japan Tobacco Inc Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor
BRPI0507628A (pt) * 2004-02-11 2007-07-03 Smithkline Beecham Corp composto ou sal farmaceuticamente aceitável do mesmo, método de tratamento de uma infecção viral em um ser humano, uso de um composto composição farmacêutica, e, processo para a preparação de um composto
PT1742642E (pt) * 2004-04-14 2009-01-23 Gilead Sciences Inc Análogos de fosfonato de compostos inibidores da integrase do hiv
EP2229945A1 (en) * 2004-05-21 2010-09-22 Japan Tobacco, Inc. Combinations comprising a 4-isoquinolone derivative and anti-HIV agents
US7176196B2 (en) 2004-05-28 2007-02-13 Bristol-Myers Squibb Company Bicyclic heterocycles as HIV integrase inhibitors
WO2006024024A2 (en) 2004-08-23 2006-03-02 Teva Pharmaceutical Industries Ltd. Solid and crystalline ibandronate sodium and processes for preparation thereof
KR101284361B1 (ko) 2004-09-02 2013-07-15 얀센 파마슈티카 엔.브이. 4-((4-((4-(2-시아노에텐일)-2,6-디메틸페닐)아미노-2-피리미딘일)아미노)벤조니트릴의 하이드로클로라이드
JP5031569B2 (ja) 2004-09-17 2012-09-19 イデニク ファルマセウチカルス インコーポレーテッド Hiv阻害剤としてのホスホインドール
WO2006096444A2 (en) 2005-03-04 2006-09-14 Smithkline Beecham Corporation Chemical compounds
PT3284520T (pt) 2005-04-28 2019-09-10 Shionogi & Co Derivado policíclico de carbamoílpiridona possuindo atividade inibidora de integrase do hiv
UA96568C2 (en) * 2005-04-28 2011-11-25 Глаксосмиткляйн Ллк Polycyclic carbamoyl pyridone derivative as hiv-integrase inhibitor
UA101141C2 (ru) * 2005-12-30 2013-03-11 Гилиад Сайенсиз, Инк. Способ улучшения фармакокинетики ингибиторов интегразы вич
KR20160074018A (ko) * 2005-12-30 2016-06-27 길리애드 사이언시즈, 인코포레이티드 Hiv 인테그라제 억제제의 약동학을 개선하기 위한 방법
NZ569347A (en) * 2006-01-20 2011-07-29 Tibotec Pharm Ltd Long term treatment of HIV-infection with 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
US20080039428A1 (en) 2006-06-29 2008-02-14 Panacos Pharmaceuticals, Inc. Antiretroviral combination therapy
US7723380B2 (en) 2006-07-21 2010-05-25 Gilead Sciences, Inc. Antiviral protease inhibitors
MX2009003410A (es) 2006-09-29 2009-07-17 Idenix Pharmaceuticals Inc Fosfoindoles enantiomericamente puros como inhibidores de vih.
TW200835693A (en) 2007-02-23 2008-09-01 Auspex Pharmaceuticals Inc Preparation and utility of non-nucleoside reverse transcriptase inhibitors
AR065439A1 (es) 2007-02-23 2009-06-10 Gilead Sciences Inc Derivados de tiazoles 1,3 no condensados,composiciones farmaceuticas que los contienen y usos como agentes antivirales, en particular anti hiv.
WO2009005693A1 (en) 2007-06-29 2009-01-08 Gilead Sciences, Inc. Novel hiv reverse transcriptase inhibitors
JP2010532350A (ja) 2007-06-29 2010-10-07 コレア リサーチ インスティテュート オブ ケミカル テクノロジー 新規のhiv逆転写酵素阻害剤
TWI448457B (zh) 2007-07-06 2014-08-11 Gilead Sciences Inc 治療劑的藥物動力學性質之調節劑
CN101743006B (zh) * 2007-07-12 2013-09-11 泰博特克药品公司 (e)4-[[4-[[4-(2-氰基乙烯基)-2,6-二甲基苯基]氨基]-2-嘧啶基]氨基]苄腈的晶型
WO2009058923A1 (en) 2007-10-31 2009-05-07 Smithkline Beecham Corporation Ccr5 antagonists as therapeutic agents
CN101990534A (zh) 2007-11-01 2011-03-23 Uab研究基金会 治疗和预防病毒感染
US8108055B2 (en) 2007-12-28 2012-01-31 Larry Wong Method, system and apparatus for controlling an electrical device
JP2011508747A (ja) 2008-01-03 2011-03-17 バイロケム ファーマ インコーポレイテッド 新規のc−21ケトルパン誘導体、それらの調製および使用
JP2011508748A (ja) * 2008-01-03 2011-03-17 バイロケム ファーマ インコーポレイテッド 新規のルパン誘導体
ES2555209T3 (es) 2008-01-04 2015-12-29 Gilead Sciences, Inc. Inhibidores del citocromo P450
AU2009214779A1 (en) 2008-02-14 2009-08-20 Virochem Pharma Inc. Novel 17beta lupane derivatives
WO2009148600A2 (en) * 2008-06-06 2009-12-10 Concert Pharmaceuticals, Inc. Deuterated lysine-based compounds
ES2448766T3 (es) * 2008-07-25 2014-03-17 Viiv Healthcare Company Profármacos de dolutegravir
US8552187B2 (en) 2008-12-11 2013-10-08 Shionogi & Co., Ltd. Processes and intermediates for carbamoylpyridone HIV integrase inhibitors
KR101847887B1 (ko) 2008-12-11 2018-04-11 시오노기세야쿠 가부시키가이샤 카르바모일피리돈 hiv 인테그라제 억제제 및 중간체의 합성
KR101883750B1 (ko) 2010-01-27 2018-07-31 비이브 헬쓰케어 컴퍼니 항바이러스 치료
GB201006038D0 (en) 2010-04-12 2010-05-26 Unilever Plc Improvements relating to antiviral compositions
CN103402516B (zh) 2010-06-17 2018-01-30 富津世生物技术有限公司 用作抗病毒药物的化合物、组合物及使用方法

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