JP2013516991A5 - - Google Patents

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Publication number
JP2013516991A5
JP2013516991A5 JP2012549089A JP2012549089A JP2013516991A5 JP 2013516991 A5 JP2013516991 A5 JP 2013516991A5 JP 2012549089 A JP2012549089 A JP 2012549089A JP 2012549089 A JP2012549089 A JP 2012549089A JP 2013516991 A5 JP2013516991 A5 JP 2013516991A5
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JP
Japan
Prior art keywords
apyrase
soluble
nucleic acid
acid construct
culture
Prior art date
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Application number
JP2012549089A
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English (en)
Japanese (ja)
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JP5913130B2 (ja
JP2013516991A (ja
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Publication date
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Priority claimed from PCT/US2011/021187 external-priority patent/WO2011088244A1/en
Publication of JP2013516991A publication Critical patent/JP2013516991A/ja
Publication of JP2013516991A5 publication Critical patent/JP2013516991A5/ja
Application granted granted Critical
Publication of JP5913130B2 publication Critical patent/JP5913130B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2012549089A 2010-01-13 2011-01-13 治療用アピラ−ゼ構築物、アピラ−ゼ作用物質、及び製造方法 Active JP5913130B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29469510P 2010-01-13 2010-01-13
US61/294,695 2010-01-13
PCT/US2011/021187 WO2011088244A1 (en) 2010-01-13 2011-01-13 Therapeutic apyrase constructs, apyrase agents, and production methods

Publications (3)

Publication Number Publication Date
JP2013516991A JP2013516991A (ja) 2013-05-16
JP2013516991A5 true JP2013516991A5 (https=) 2014-02-27
JP5913130B2 JP5913130B2 (ja) 2016-04-27

Family

ID=44304650

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012549089A Active JP5913130B2 (ja) 2010-01-13 2011-01-13 治療用アピラ−ゼ構築物、アピラ−ゼ作用物質、及び製造方法

Country Status (10)

Country Link
US (1) US8771683B2 (https=)
EP (1) EP2523971B1 (https=)
JP (1) JP5913130B2 (https=)
KR (1) KR20130009744A (https=)
AU (1) AU2011205248A1 (https=)
BR (1) BR112012017243A2 (https=)
CA (1) CA2787016C (https=)
IL (1) IL220882A0 (https=)
RU (1) RU2012134366A (https=)
WO (1) WO2011088244A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2941254B1 (en) * 2014-03-12 2017-01-11 Shiseido Company, Ltd. Agent for sedating response to external stimulation in skin and method for sedating that response technical field
CN105018442A (zh) * 2014-04-23 2015-11-04 Apt治疗公司 改进的en-腺苷三磷酸双磷酸酶
UY38299A (es) 2018-07-18 2020-02-28 Novartis Ag Apirasas solubilizadas, métodos y usos
TW202146042A (zh) * 2020-03-06 2021-12-16 瑞典商阿斯特捷利康公司 用於治療動脈和靜脈血栓形成的協同且靶向的組成物
CA3098818A1 (en) 2020-08-19 2022-02-19 Astrazeneca Ab Combination treatment
JP7547996B2 (ja) * 2020-12-22 2024-09-10 トヨタ自動車株式会社 コイルの製造方法
WO2024089196A1 (en) 2022-10-28 2024-05-02 Astrazeneca Ab Recombinant apyrase protein for use in the treatment of an ischemic event at a dose of 40-240 mg

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5322678A (en) 1988-02-17 1994-06-21 Neorx Corporation Alteration of pharmacokinetics of proteins by charge modification
KR100545945B1 (ko) * 2000-07-03 2006-01-25 갈라 디자인, 인크. 발현 벡터
US7247300B1 (en) 2002-11-07 2007-07-24 Apt Therapeutics, Inc. Therapeutic use of soluble CD39L3
EP1733045A4 (en) 2004-02-27 2008-08-13 Apt Therapeutics Inc DESIGN AND THERAPEUTIC USE OF ADPASE-ENHANCED APYRASES
TWI384069B (zh) * 2004-08-27 2013-02-01 Pfizer Ireland Pharmaceuticals 多胜肽之製法

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