JP2013514152A5 - - Google Patents

Download PDF

Info

Publication number
JP2013514152A5
JP2013514152A5 JP2012544750A JP2012544750A JP2013514152A5 JP 2013514152 A5 JP2013514152 A5 JP 2013514152A5 JP 2012544750 A JP2012544750 A JP 2012544750A JP 2012544750 A JP2012544750 A JP 2012544750A JP 2013514152 A5 JP2013514152 A5 JP 2013514152A5
Authority
JP
Japan
Prior art keywords
particles
radiopaque agent
assembly
agent
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012544750A
Other languages
English (en)
Japanese (ja)
Other versions
JP5820815B2 (ja
JP2013514152A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/060474 external-priority patent/WO2011084465A2/en
Publication of JP2013514152A publication Critical patent/JP2013514152A/ja
Publication of JP2013514152A5 publication Critical patent/JP2013514152A5/ja
Application granted granted Critical
Publication of JP5820815B2 publication Critical patent/JP5820815B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012544750A 2009-12-15 2010-12-15 インプラントおよび生体分解性基準マーカー Active JP5820815B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28645009P 2009-12-15 2009-12-15
US61/286,450 2009-12-15
PCT/US2010/060474 WO2011084465A2 (en) 2009-12-15 2010-12-15 Implants and biodegradable fiducial markers

Publications (3)

Publication Number Publication Date
JP2013514152A JP2013514152A (ja) 2013-04-25
JP2013514152A5 true JP2013514152A5 (cg-RX-API-DMAC7.html) 2014-02-06
JP5820815B2 JP5820815B2 (ja) 2015-11-24

Family

ID=44143217

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012544750A Active JP5820815B2 (ja) 2009-12-15 2010-12-15 インプラントおよび生体分解性基準マーカー

Country Status (8)

Country Link
US (12) US8383161B2 (cg-RX-API-DMAC7.html)
EP (3) EP3583960A1 (cg-RX-API-DMAC7.html)
JP (1) JP5820815B2 (cg-RX-API-DMAC7.html)
CN (1) CN102844054B (cg-RX-API-DMAC7.html)
AU (1) AU2010340067B2 (cg-RX-API-DMAC7.html)
CA (3) CA3042067C (cg-RX-API-DMAC7.html)
IN (1) IN2012DN05177A (cg-RX-API-DMAC7.html)
WO (1) WO2011084465A2 (cg-RX-API-DMAC7.html)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10675298B2 (en) * 2006-07-27 2020-06-09 Boston Scientific Scimed Inc. Particles
EP3583960A1 (en) 2009-12-15 2019-12-25 Incept, LLC Implants and biodegradable fiducial markers
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
JP6199883B2 (ja) 2011-12-05 2017-09-20 インセプト・リミテッド・ライアビリティ・カンパニーIncept,Llc 医療用オルガノゲルプロセス及び組成物
WO2013112350A1 (en) * 2012-01-24 2013-08-01 Lifecell Corporation Elongated tissue matrices
US9798856B2 (en) * 2012-03-21 2017-10-24 Koninklijke Philips N.V. Clinical workstation integrating medical imaging and biopsy data and methods using same
US9226797B2 (en) * 2012-11-04 2016-01-05 Miba Medical Inc. Computer aided implantation of body implants
US9220807B2 (en) * 2012-11-04 2015-12-29 Miba Medical Inc. Non-toxic cross-linker for hyaluronic acid
CN105407955B (zh) * 2013-03-15 2018-11-13 波士顿科学公司 输送药物的装置和方法
CA2906574C (en) 2013-03-15 2021-08-31 Matthew R. Dreher Imageable embolic microsphere
AU2014270358B2 (en) * 2013-05-24 2019-01-17 Nanovi Radiotherapy Aps Gel formulations for guiding radiotherapy
CA2915430A1 (en) * 2013-06-20 2014-12-24 Nanobiotix Compositions and methods for use in medical diagnosis
RS58800B1 (sr) * 2013-06-20 2019-07-31 Nanobiotix Kompozicije za upotrebu u onkologiji
US10842969B2 (en) 2013-10-25 2020-11-24 Mercator Medsystems, Inc. Systems and methods of treating malacia by local delivery of hydrogel to augment tissue
US10743909B2 (en) 2014-04-03 2020-08-18 Corbin Clinical Resources, Llc Transperineal prostate biopsy device, systems, and methods of use
US12144519B2 (en) * 2014-04-03 2024-11-19 Corbin Clinical Resources, Llc Transperineal prostate biopsy and treatment methods
US10022475B2 (en) * 2014-05-01 2018-07-17 Bao Tran Body augmentation device
US9561095B1 (en) * 2015-10-12 2017-02-07 Phi Nguyen Body augmentation device
US9636210B2 (en) 2014-05-19 2017-05-02 Mentor Worldwide Llc Injection zone markers for biomedical implants
US9678022B2 (en) * 2014-09-05 2017-06-13 The Boeing Company Nonaqueous radiopaque fluid and associated imaging system and method
KR101555358B1 (ko) * 2014-10-21 2015-09-24 사회복지법인 삼성생명공익재단 생분해성 다중블록 공중합체를 이용한 표적 표지자
US10550187B2 (en) 2014-10-24 2020-02-04 Incept, Llc Extra luminal scaffold
KR20170117384A (ko) 2014-12-10 2017-10-23 인셉트, 엘엘씨 히드로겔 약물 전달 임플란트
RU2729731C2 (ru) 2014-12-15 2020-08-11 Зе Джонс Хопкинс Юниверсити Составы на основе сунитиниба и способы их применения для лечения глазных заболеваний
GB201505527D0 (en) 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
US9855317B2 (en) 2015-04-27 2018-01-02 Reflex Medical, Inc. Systems and methods for sympathetic cardiopulmonary neuromodulation
EP3294212B1 (en) 2015-05-12 2023-10-25 Incept, LLC Drug delivery from hydrogels
JP2018516256A (ja) 2015-05-28 2018-06-21 ナノビオティックスNanobiotix 治療用ワクチンとしての使用のためのナノ粒子
US20170103184A1 (en) * 2015-10-12 2017-04-13 Phi Nguyen Injectable filler
EP3373978A4 (en) 2015-11-12 2019-06-26 Graybug Vision, Inc. AGGREGATION OF MICROPARTICLES FOR THERAPY
US10155063B2 (en) 2015-11-12 2018-12-18 University Of Virginia Patent Foundation Methods for vas-occlusive contraception and reversal thereof
US10420724B2 (en) 2015-11-25 2019-09-24 Incept, Llc Shape changing drug delivery devices and methods
WO2017139487A1 (en) 2016-02-09 2017-08-17 Northwind Medical, Inc. Methods, agents, and devices for local neuromodulation of autonomic nerves
US11154547B2 (en) 2016-06-29 2021-10-26 Tulavi Therapeutics, Inc. Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system
EP3481373A4 (en) * 2016-07-07 2020-04-01 University of Virginia Patent Foundation THIOL-MICHAEL-ADDED HYDROGEL-BASED CURIETHERAPY SYSTEM AND METHODS COMPRISING SAME
US20220249366A1 (en) * 2016-07-07 2022-08-11 University Of Virginia Patent Foundation Thiol-michael addition hydrogel-based brachytherapy system and methods comprising the same
CN106334213B (zh) * 2016-08-31 2019-07-26 安疗生命科学(武汉)有限公司 一种血管栓塞材料、其制备方法及在药物制备中的用途
KR20230053707A (ko) 2016-09-23 2023-04-21 인셉트, 엘엘씨 전안방내 약물 전달 데포
CN110022789B (zh) * 2016-11-23 2022-07-12 霍罗吉克公司 活检部位标记物
CA3053451A1 (en) 2017-01-05 2018-07-12 Contraline, Inc. Methods for implanting and reversing stimuli-responsive implants
US12383421B2 (en) 2017-01-05 2025-08-12 Contraline, Inc. Contraceptive devices
US20180289467A1 (en) * 2017-04-05 2018-10-11 Ernesto Andrade Dispensing device, kit, and method for tissue augmentation
WO2018209155A1 (en) 2017-05-10 2018-11-15 Graybug Vision, Inc. Extended release microparticles and suspensions thereof for medical therapy
CN107307922A (zh) * 2017-07-06 2017-11-03 刘志光 一种人体植入填充颗粒的制作方法
CA3063913A1 (en) * 2017-07-07 2019-01-10 Shadwell Endoscopic, Inc. System and method for marking and subsequently locating sites of biopsies using rfid technology
KR102673196B1 (ko) 2017-09-05 2024-06-10 삼성전자주식회사 유기금속 화합물, 이를 포함한 유기 발광 소자 및 이를 포함한 진단용 조성물
CN111432807A (zh) 2017-10-06 2020-07-17 铸造疗法股份有限公司 用于控制释放治疗剂的可植入贮库
US10426424B2 (en) 2017-11-21 2019-10-01 General Electric Company System and method for generating and performing imaging protocol simulations
CN111655303A (zh) 2018-01-08 2020-09-11 铸造疗法股份有限公司 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法
US11123445B2 (en) 2018-03-07 2021-09-21 Margin-Clear Pty Ltd Topical brachytherapy device and method of treatment of malignant cancer cells
CN112367980A (zh) 2018-05-12 2021-02-12 铸造疗法股份有限公司 用于控制释放治疗剂的可植入贮库
CN112384256A (zh) 2018-05-15 2021-02-19 因赛普特有限责任公司 栓塞组合物及方法
CN117599244A (zh) 2018-07-02 2024-02-27 图拉维治疗股份有限公司 原位形成神经帽的方法和装置
US20210315587A1 (en) 2018-07-02 2021-10-14 Tulavi Therapeutics, Inc. Methods and devices for in situ formed nerve cap with rapid release
WO2020047013A1 (en) 2018-08-28 2020-03-05 Foundry Therapeutics, Inc. Polymer implants
USD896383S1 (en) 2018-09-13 2020-09-15 Allergan, Inc. Tissue expansion device
EP3849458A1 (en) 2018-09-13 2021-07-21 Allergan, Inc. Tissue expansion device
US11253391B2 (en) 2018-11-13 2022-02-22 Contraline, Inc. Systems and methods for delivering biomaterials
AU2020269368B2 (en) * 2019-05-03 2025-07-10 Palette Life Sciences, Inc. Improved tissue spacers
JP7355858B2 (ja) * 2019-06-12 2023-10-03 ヌーリオン ケミカルズ インターナショナル ベスローテン フェノーツハップ 水性側流からカルボン酸を単離するための方法
HUE063796T2 (hu) 2019-06-12 2024-01-28 Nouryon Chemicals Int Bv Eljárás diacil-peroxidok elõállítására
WO2020249688A1 (en) 2019-06-12 2020-12-17 Nouryon Chemicals International B.V. Process for the production of diacyl peroxides
ES2961184T3 (es) 2019-06-12 2024-03-08 Nouryon Chemicals Int Bv Proceso para la producción de peróxidos de diacilo
ES2963309T3 (es) 2019-06-12 2024-03-26 Nouryon Chemicals Int Bv Proceso para la producción de peroxiésteres
US11878092B2 (en) 2019-08-28 2024-01-23 Boston Scientific Scimed, Inc. Medical compositions based on crosslinkable hydrophilic polymers
WO2021041222A1 (en) 2019-08-28 2021-03-04 Boston Scientific Scimed, Inc. Multi-armed polyoxazolines and compositions, systems and methods pertaining to the same
EP4021960A1 (en) 2019-08-28 2022-07-06 Boston Scientific Scimed Inc. Reactive multi-arm polymers having branched end groups
WO2021041225A1 (en) 2019-08-28 2021-03-04 Boston Scientific Scimed, Inc. Multi-armed polymers comprising free-radical-polymerizable monomers
CN114206984A (zh) 2019-08-28 2022-03-18 波士顿科学医学有限公司 不透射线的多臂聚合物以及与其相关的组合物、系统和方法
WO2021041227A1 (en) 2019-08-28 2021-03-04 Boston Scientific Scimed, Inc. Multifunctional nitroxide-mediated polymerization initiators and products formed therefrom
WO2021145325A1 (ja) * 2020-01-14 2021-07-22 持田製薬株式会社 アルギン酸塩を使用した対象の処置のための組合せ及び方法
WO2021158546A1 (en) 2020-02-04 2021-08-12 Boston Scientific Scimed, Inc. Injectable in vivo crosslinking materials for use as soft tissue fillers
CN111905155B (zh) * 2020-07-23 2021-10-15 北京诺康达医药科技股份有限公司 一种封闭水凝胶及其制备方法和应用
US12343454B2 (en) 2020-11-12 2025-07-01 Pramand LLC Hydrogels formed in situ and composition design for intrauterine use
EP4422596A1 (en) 2021-10-25 2024-09-04 Boston Scientific Scimed Inc. Iodine labeled hydrogels and precursors thereof with improved radiopacity
WO2023136639A1 (ko) * 2022-01-13 2023-07-20 국립암센터 생체 친화적 목적 병변 표지용 조성물 및 이의 제조 방법
JP7744528B2 (ja) 2022-02-02 2025-09-25 ボストン サイエンティフィック サイムド,インコーポレイテッド ヨウ素化化合物及びこれから形成されるヒドロゲル
CN114344554A (zh) * 2022-02-11 2022-04-15 上海益思妙医疗器械有限公司 一种peg化合物作为制备栓塞剂的应用
US11701451B1 (en) 2022-03-11 2023-07-18 Carbon Medical Technologies, Inc. Soft tissue filler and methods
US12251466B2 (en) 2022-04-20 2025-03-18 Pramand LLC Single solution hydrogels with covalent bonding formed in situ, composition design and medical procedures using the hydrogels
US12440599B2 (en) 2022-05-06 2025-10-14 Pramand LLC Water activated hydrogel-based medical patches, and methods of making and using such patches
US20250360172A1 (en) * 2022-05-25 2025-11-27 Cedars-Sinai Medical Center Microgel-encapsulated ipsc-derived notochordal cells for treatment of intervertebral disc degeneration and discogenic pain
WO2024040166A1 (en) 2022-08-17 2024-02-22 Boston Scientific Scimed, Inc. Iodine labeled hydrogels and precursors thereof with improved properties
EP4623020A1 (en) 2022-11-21 2025-10-01 Boston Scientific Scimed Inc. Iodine labeled hydrogels and crosslinking agents for forming the same
CN120826427A (zh) 2023-03-02 2025-10-21 波士顿科学医学有限公司 多氨基碘化化合物和由其形成的不透射线的水凝胶
CN120826240A (zh) 2023-03-02 2025-10-21 波士顿科学医学有限公司 释放治疗剂的水凝胶及其前体
DE102023108039A1 (de) 2023-03-29 2024-10-02 Dwi - Leibniz-Institut Für Interaktive Materialien E.V. Ein System zur Herstellung eines degradierbaren Hydrogels
US20240358896A1 (en) * 2023-04-28 2024-10-31 Boston Scientific Scimed, Inc. Suspensions of radiopaque crosslinked hydrogel particles in carrier fluids containing biocompatible hydrophilic polymers
WO2025096930A1 (en) 2023-11-01 2025-05-08 Boston Scientific Scimed, Inc. Amino-acid- and amino-alcohol-based polyamine compounds and medical hydrogels formed therefrom
US20250228774A1 (en) * 2024-01-11 2025-07-17 Boston Scientific Scimed, Inc. Systems and methods for accelerated hydrolysis of polysaccharide-based hydrogels

Family Cites Families (146)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3640741A (en) 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
US3865108A (en) 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
US3872856A (en) 1971-06-09 1975-03-25 Ralph S Clayton Apparatus for treating the walls and floor of the pelvic cavity with radiation
US4002173A (en) 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
DE2437629C3 (de) 1974-08-05 1978-09-21 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von unlöslichen in Wasser nur wenig quellbaren Polymerisaten von N-Vinyllactamen
US4014335A (en) * 1975-04-21 1977-03-29 Alza Corporation Ocular drug delivery device
US4193813A (en) * 1976-09-07 1980-03-18 Medi-Coll, Inc. Method for making collagen sponge
US4207893A (en) 1977-08-29 1980-06-17 Alza Corporation Device using hydrophilic polymer for delivering drug to biological environment
IL74715A0 (en) * 1984-03-27 1985-06-30 Univ New Jersey Med Biodegradable matrix and methods for producing same
US4697575A (en) 1984-11-21 1987-10-06 Henry Ford Hospital Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member
US4714074A (en) 1985-06-28 1987-12-22 Centre National De La Recherche Scientifique Method for protecting human or animal organs against radiation
US5160745A (en) 1986-05-16 1992-11-03 The University Of Kentucky Research Foundation Biodegradable microspheres as a carrier for macromolecules
US4741872A (en) 1986-05-16 1988-05-03 The University Of Kentucky Research Foundation Preparation of biodegradable microspheres useful as carriers for macromolecules
IL82834A (en) 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5306500A (en) 1988-11-21 1994-04-26 Collagen Corporation Method of augmenting tissue with collagen-polymer conjugates
US5304595A (en) * 1988-11-21 1994-04-19 Collagen Corporation Collagen-polymer conjugates
US5550187A (en) * 1988-11-21 1996-08-27 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
IL90193A (en) 1989-05-04 1993-02-21 Biomedical Polymers Int Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
US5324519A (en) * 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
US5529914A (en) * 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
CA2094908C (en) * 1990-12-06 2000-02-08 Byron Kent Hayes Implantable bioabsorbable article
FR2672713A1 (fr) * 1991-02-13 1992-08-14 Inst Nat Polytech Grenoble Composant d'alimentation du type carte de credit.
US5629008A (en) * 1992-06-02 1997-05-13 C.R. Bard, Inc. Method and device for long-term delivery of drugs
US5514379A (en) * 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
US6592859B1 (en) * 1992-08-20 2003-07-15 Ethicon, Inc. Controlled expansion sphincter augmentation media
CA2144407C (en) * 1992-09-10 2000-05-30 Charles B. Berde Biodegradable polymer matrices for sustained delivery of local anesthetic agents
DE69412474T2 (de) * 1993-04-28 1998-12-17 Focal, Inc., Lexington, Mass. Vorrichtung, produkt und verwendung betreffend die intraluminale photothermoformgebung
US5565215A (en) * 1993-07-23 1996-10-15 Massachusettes Institute Of Technology Biodegradable injectable particles for imaging
US5499994A (en) 1993-07-30 1996-03-19 American Medical Systems, Inc. Dilation device for the urethra
CA2188464C (en) 1994-04-27 2006-08-08 Michael Roreger Collagen preparation for the controlled release of active substances
DE4414755C2 (de) 1994-04-27 2000-11-16 Lohmann Therapie Syst Lts Kollagenzubereitung zur gesteuerten Abgabe von Wirkstoffen, Verfahren und Verwendung
US5900245A (en) * 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
CA2215309C (en) * 1995-03-23 2008-11-25 Focal, Inc. Redox and photoinitiator systems for priming for improved adherence of gels to substrates
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US6129761A (en) * 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US5855915A (en) 1995-06-30 1999-01-05 Baylor University Tablets or biologically acceptable implants for long-term antiinflammatory drug release
ATE342295T1 (de) * 1995-07-28 2006-11-15 Genzyme Corp Biologische abbaubare multiblokhydrogene und ihre verwendung wie trägerstoffe fur kontrollierte freisetzung pharmakologisch activen werstoffe und gewebekontaktmaterialen
US5759583A (en) * 1995-08-30 1998-06-02 Syntex (U.S.A.) Inc. Sustained release poly (lactic/glycolic) matrices
US5733316A (en) 1995-10-27 1998-03-31 Dornier Medical Systems, Inc. Organ separation for thermal therapy
US5863984A (en) * 1995-12-01 1999-01-26 Universite Laval, Cite Universitaire Biostable porous material comprising composite biopolymers
US5752974A (en) * 1995-12-18 1998-05-19 Collagen Corporation Injectable or implantable biomaterials for filling or blocking lumens and voids of the body
PT876165E (pt) 1995-12-18 2006-10-31 Angiotech Biomaterials Corp Composicoes de polimeros reticulados e processos para a sua utilizacao
US6060534A (en) * 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
US7049346B1 (en) * 1996-08-20 2006-05-23 Menlo Care Div Of Ethicon, Inc. Swollen hydrogel for sphincter augmentation
US6063061A (en) 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US20020064546A1 (en) * 1996-09-13 2002-05-30 J. Milton Harris Degradable poly(ethylene glycol) hydrogels with controlled half-life and precursors therefor
AU4648697A (en) * 1996-09-23 1998-04-14 Chandrashekar Pathak Methods and devices for preparing protein concentrates
ZA978537B (en) * 1996-09-23 1998-05-12 Focal Inc Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
US6566406B1 (en) * 1998-12-04 2003-05-20 Incept, Llc Biocompatible crosslinked polymers
US7009034B2 (en) 1996-09-23 2006-03-07 Incept, Llc Biocompatible crosslinked polymers
US6214966B1 (en) 1996-09-26 2001-04-10 Shearwater Corporation Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
US5932539A (en) * 1996-10-15 1999-08-03 The Board Of Trustees Of The University Of Illinois Biodegradable polymer matrix for tissue repair
JP3092530B2 (ja) 1996-11-05 2000-09-25 日本油脂株式会社 コハク酸イミジル基置換ポリオキシアルキレン誘導体の製造方法
JP3092531B2 (ja) 1996-11-05 2000-09-25 日本油脂株式会社 コハク酸イミジル基置換ポリオキシアルキレン誘導体の製造方法
US6371975B2 (en) 1998-11-06 2002-04-16 Neomend, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
US6224893B1 (en) * 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US6271278B1 (en) * 1997-05-13 2001-08-07 Purdue Research Foundation Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties
IL121861A (en) 1997-09-29 2003-07-31 Moshe Ein Gal Prostate radiotherapy apparatus
WO1999018886A1 (en) * 1997-10-10 1999-04-22 Corbitt John D Jr Breast implant
US8288745B2 (en) 1997-10-10 2012-10-16 Senorx, Inc. Method of utilizing an implant for targeting external beam radiation
AU743819B2 (en) 1997-10-27 2002-02-07 California Institute Of Technology Methods and pharmaceutical compositions for the closure of retinal breaks
DE69825619T2 (de) * 1997-11-07 2005-09-01 Rutgers, The State University Strikt alternierende poly(alkylenoxid)copolymere
US6375634B1 (en) 1997-11-19 2002-04-23 Oncology Innovations, Inc. Apparatus and method to encapsulate, kill and remove malignancies, including selectively increasing absorption of x-rays and increasing free-radical damage to residual tumors targeted by ionizing and non-ionizing radiation therapy
US6660301B1 (en) * 1998-03-06 2003-12-09 Biosphere Medical, Inc. Injectable microspheres for dermal augmentation and tissue bulking
US6428978B1 (en) * 1998-05-08 2002-08-06 Cohesion Technologies, Inc. Methods for the production of gelatin and full-length triple helical collagen in recombinant cells
US6066856A (en) 1998-05-18 2000-05-23 Children's Medical Center Corporation Radiation protective device
US6280742B1 (en) * 1998-06-17 2001-08-28 Zonagen, Inc. Methods and materials for the treatment of prostatic carcinoma
US6206930B1 (en) 1998-08-10 2001-03-27 Charlotte-Mecklenburg Hospital Authority Absorbable tissue expander
US6703047B2 (en) * 2001-02-02 2004-03-09 Incept Llc Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use
US6152943A (en) 1998-08-14 2000-11-28 Incept Llc Methods and apparatus for intraluminal deposition of hydrogels
US6818018B1 (en) * 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
DE69943297D1 (de) 1998-08-14 2011-05-05 Incept Llc Apparat für die in-situ-bildung von hydrogelen
US6514534B1 (en) * 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
US6179862B1 (en) * 1998-08-14 2001-01-30 Incept Llc Methods and apparatus for in situ formation of hydrogels
US6605294B2 (en) 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US6632457B1 (en) 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
DE69916643T2 (de) 1998-10-22 2005-04-28 Bioniche Life Sciences Inc., London Verwendung von hyaluronsäure zur behandlung der bestrahlungs-blasenentzündung
US8802146B2 (en) 1998-11-06 2014-08-12 Neomend, Inc. Systems, methods, and compositions for prevention of tissue adhesion
US6899889B1 (en) 1998-11-06 2005-05-31 Neomend, Inc. Biocompatible material composition adaptable to diverse therapeutic indications
AU1614500A (en) 1998-11-12 2000-06-05 Canadian Prostate Centre, Inc. Apparatus and method of separating organs to enable aggressive thermal therapy
US6110484A (en) * 1998-11-24 2000-08-29 Cohesion Technologies, Inc. Collagen-polymer matrices with differential biodegradability
US20080114092A1 (en) 1998-12-04 2008-05-15 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
TW392930U (en) * 1998-12-28 2000-06-01 Hon Hai Prec Ind Co Ltd Electric connector
US6958212B1 (en) * 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
US6862470B2 (en) * 1999-02-02 2005-03-01 Senorx, Inc. Cavity-filling biopsy site markers
BR0007974A (pt) * 1999-02-03 2001-10-30 Powderject Res Ltd Usos de um agente farmacologicamente ativo, deum constructo de gene e de um antìgeno, métodospara produzir uma composição farmacêutica em póe para administrar uma droga a um indivìduo emnecessidade dela, composição farmacêutica, formade dosagem unitária, e, artigo de manufatura parasuprimento transdérmico ou transmucoso de umagente farmacologicamente ativo a um indivìduo
US6177514B1 (en) * 1999-04-09 2001-01-23 Sulzer Carbomedics Inc. Blocked functional reagants for cross-linking biological tissues
ES2298135T3 (es) * 1999-04-12 2008-05-16 Cornell Research Foundation, Inc. Sistema formador de hidrogel con componentes hidrofobos e hidrofilos.
US6268405B1 (en) * 1999-05-04 2001-07-31 Porex Surgical, Inc. Hydrogels and methods of making and using same
US6426145B1 (en) 1999-05-20 2002-07-30 Scimed Life Systems, Inc. Radiopaque compositions for visualization of medical devices
US6428785B1 (en) * 1999-10-28 2002-08-06 Immunolytics Inc. Method and composition for treating prostate cancer
AU1658601A (en) * 1999-11-15 2001-05-30 The Texas A & M University System Wound sealant formed in situ
US6479079B1 (en) * 1999-12-13 2002-11-12 Sulzer Carbomedics Inc. Anticalcification treatments for fixed biomaterials
US6436424B1 (en) * 2000-03-20 2002-08-20 Biosphere Medical, Inc. Injectable and swellable microspheres for dermal augmentation
US9314339B2 (en) * 2000-03-27 2016-04-19 Formae, Inc. Implants for replacing cartilage, with negatively-charged hydrogel surfaces and flexible matrix reinforcement
US6656200B2 (en) 2000-04-07 2003-12-02 Collagen Matrix, Inc. Embolization device
US7771482B1 (en) 2000-05-09 2010-08-10 Ben-Zion Karmon Method for tissue expansion and regeneration using bioresorbable inflatable devices
US6599448B1 (en) * 2000-05-10 2003-07-29 Hydromer, Inc. Radio-opaque polymeric compositions
US6383344B1 (en) 2000-07-19 2002-05-07 Genzyme Corporation Molecular weight reduction of polymer using irradiation treatment
US6545097B2 (en) * 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
US6596471B2 (en) * 2000-12-21 2003-07-22 Carbomedics Inc. Method of cross-linking tissue with a bis-maleimide compound
CA2438193A1 (en) * 2001-02-26 2002-09-06 Duke University Novel dendritic polymers and their biomedical uses
JP4123856B2 (ja) 2001-07-31 2008-07-23 日油株式会社 生体関連物質の修飾剤およびポリオキシアルキレン誘導体の製造方法
JPWO2003031388A1 (ja) 2001-10-03 2005-01-20 大日本除蟲菊株式会社 プロパルギルベンジルアルコールエステル誘導体、その製造法、およびこれを含有する殺虫・防虫剤
US20070264227A1 (en) * 2001-11-07 2007-11-15 Eidgenossische Technische Hochschule Zurich Synthetic Matrix for Controlled Cell Ingrowth and Tissue Regeneration
US20040131582A1 (en) 2002-02-26 2004-07-08 Grinstaff Mark W. Novel dendritic polymers and their biomedical uses
US7341716B2 (en) * 2002-04-12 2008-03-11 Boston Scientific Scimed, Inc. Occlusive composition
AU2003243755A1 (en) 2002-06-24 2004-01-06 William R. Noyes Fillers and methods for displacing tissues to improve radiological outcomes
US7351430B2 (en) 2002-11-06 2008-04-01 Uluru Inc. Shape-retentive hydrogel particle aggregates and their uses
US7129210B2 (en) 2003-07-23 2006-10-31 Covalent Medical, Inc. Tissue adhesive sealant
US20050033157A1 (en) * 2003-07-25 2005-02-10 Klein Dean A. Multi-modality marking material and method
US7790141B2 (en) 2003-08-11 2010-09-07 Pathak Holdings, Llc Radio-opaque compounds, compositions containing same and methods of their synthesis and use
CA2531894C (en) 2003-09-25 2014-02-11 Rutgers, The State University Inherently radiopaque polymeric products for embolotherapy
CA2571304A1 (en) 2004-06-23 2006-01-05 Bioprotect Ltd. Device system and method for tissue displacement or separation
FR2872262B1 (fr) 2004-06-29 2010-11-26 Air Liquide Procede et installation de fourniture de secours d'un gaz sous pression
WO2006031358A2 (en) 2004-08-13 2006-03-23 Hyperbranch Medical Technology, Inc. Dendritic polymers, crosslinked gels, and their uses as ophthalmic sealants and lenses
CN101014642B (zh) 2004-08-13 2010-04-21 雷瓦医药公司 用于多种应用的固有不透射线的可生物再吸收的聚合物
WO2006031388A2 (en) 2004-08-20 2006-03-23 Hyperbranch Medical Technology, Inc. Dentritic polymers, crosslinked gels, and their uses in orthopedic applications
US7919112B2 (en) 2004-08-26 2011-04-05 Pathak Holdings, Llc Implantable tissue compositions and method
WO2006078770A2 (en) 2005-01-21 2006-07-27 Civco Medical Instruments Co., Inc. Creating temporary space between body tissues
US7963287B2 (en) * 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
WO2007001926A2 (en) 2005-06-24 2007-01-04 Hyperbranch Medical Technology, Inc. Low-swelling hydrogel sealants for wound repair
WO2007005249A2 (en) 2005-06-29 2007-01-11 Hyperbranch Medical Technology, Inc. Nanoparticles and dendritic-polymer-based hydrogels comprising them
DE102005051366A1 (de) 2005-10-25 2007-04-26 Degussa Gmbh Drug Delivery Systeme
AU2007204872B2 (en) 2006-01-11 2013-04-04 Hyperbranch Medical Technology, Inc. Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices
US8795709B2 (en) * 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
CA2650473C (en) 2006-04-24 2013-06-18 Incept, Llc Protein crosslinkers, crosslinking methods and applications thereof
US7872068B2 (en) 2006-05-30 2011-01-18 Incept Llc Materials formable in situ within a medical device
JP2010519183A (ja) 2007-02-06 2010-06-03 インセプト エルエルシー 生理溶液の溶出のためのタンパク質の沈殿を用いる重合
US20100104625A1 (en) 2007-02-16 2010-04-29 Cornell University Biodegradable compositions and materials
US20080220047A1 (en) 2007-03-05 2008-09-11 Sawhney Amarpreet S Low-swelling biocompatible hydrogels
US9987221B2 (en) 2007-08-23 2018-06-05 Boston Scientific Scimed, Inc. Injectable hydrogel compositions
WO2009059121A1 (en) 2007-11-02 2009-05-07 Genzyme Corporation Methods of augmenting or repairing soft tissue
JP5739668B2 (ja) 2008-02-13 2015-06-24 ハイパーブランチ メディカル テクノロジー, インコーポレイテッド 調節可能な分解速度を有する架橋ポリアルキレンイミンヒドロゲル
CN101724144A (zh) 2008-11-03 2010-06-09 北京键凯科技有限公司 新型的多臂聚乙二醇及其制备方法和应用
JP5788326B2 (ja) 2008-11-03 2015-09-30 コーネル ユニバーシティー ジヒドロキシアセトンのポリマー組成物およびその使用
EP3583960A1 (en) 2009-12-15 2019-12-25 Incept, LLC Implants and biodegradable fiducial markers
US8734930B2 (en) 2010-05-27 2014-05-27 Covidien Lp Hydrogel implants with varying degrees of crosslinking
JP2016508536A (ja) 2013-02-08 2016-03-22 エンドゥーシェイプ インコーポレイテッド 医療機器のための放射線不透過性ポリマー
US9789073B2 (en) 2013-03-14 2017-10-17 Pathak Holdings, Llc Compositions, methods and devices for local drug delivery
CN107759783A (zh) 2013-12-02 2018-03-06 北京键凯科技股份有限公司 炔基多臂聚乙二醇衍生物
CN106146325B (zh) 2015-04-24 2019-01-29 北京键凯科技股份有限公司 一种y型多缩乙二醇衍生物及其制备方法
US20200277449A1 (en) * 2017-09-15 2020-09-03 Université De Strasbourg Injectable hybrid alginate hydrogels and uses thereof

Similar Documents

Publication Publication Date Title
JP2013514152A5 (cg-RX-API-DMAC7.html)
Eivazzadeh-Keihan et al. Hybrid bionanocomposite containing magnesium hydroxide nanoparticles embedded in a carboxymethyl cellulose hydrogel plus silk fibroin as a scaffold for wound dressing applications
Kankariya et al. Biomedical application of chitosan and chitosan derivatives: a comprehensive review
Islam et al. Chitin and chitosan: structure, properties and applications in biomedical engineering
Wang et al. Adhesive, self-healing, and antibacterial chitosan hydrogels with tunable two-layer structures
Hao et al. Rational design and preparation of functional hydrogels for skin wound healing
CN107320786B (zh) 一种缓释抗感染的复合软组织修复材料及其制备方法
Yang et al. Biomimetic design of double-sided functionalized silver nanoparticle/bacterial cellulose/hydroxyapatite hydrogel mesh for temporary cranioplasty
Nur et al. Recent advances in bioactive wound dressings
Bal-Öztürk et al. Innovative approaches in skin therapy: bionanocomposites for skin tissue repair and regeneration
Alam et al. Nanofiber-based systems for stimuli-responsive and dual drug delivery: present scenario and the way forward
Emre Oz et al. A review of functionalised bacterial cellulose for targeted biomedical fields
Balavigneswaran et al. Mussel-inspired adhesive hydrogels based on Laponite-confined dopamine polymerization as a transdermal patch
Phulmogare et al. Fucoidan loaded PVA/Dextran blend electrospun nanofibers for the effective wound healing
Pelegrino et al. Chitosan-Based Nanomaterials for Skin Regeneration.
Tang et al. Modified bacterial cellulose for biomedical applications
Aljabali et al. Nanocelluloses as a novel vehicle for controlled drug delivery
Gu et al. Recent Advances in Biomacromolecule‐Reinforced 2D Material (2DM) Hydrogels: From Interactions, Synthesis, and Functionalization to Biomedical Applications
CN108478843A (zh) 具有含铜涂层的医用敷料及其制备方法
Zhang et al. Multicomponent synergistic antibacterial hydrogel based on gelatin-oxidized carboxymethyl cellulose for wound healing of drug-resistant chronic infection
Tamnna et al. Advances in polymer-based scaffolding for enhanced wound healing: a comprehensive review
Sharma et al. In vitro and in vivo studies of pH-sensitive GHK-Cu-Incorporated polyaspartic and polyacrylic acid superabsorbent polymer
Tu et al. Incorporation of Layered Rectorite into Biocompatible Core–Sheath Nanofibrous Mats for Sustained Drug Delivery
Ilomuanya Hydrogels as biodegradable biopolymer formulations
Mao et al. Recent advances of multifunctional cellulose-based hydrogels