JP2013513109A5 - - Google Patents

Download PDF

Info

Publication number
JP2013513109A5
JP2013513109A5 JP2012542118A JP2012542118A JP2013513109A5 JP 2013513109 A5 JP2013513109 A5 JP 2013513109A5 JP 2012542118 A JP2012542118 A JP 2012542118A JP 2012542118 A JP2012542118 A JP 2012542118A JP 2013513109 A5 JP2013513109 A5 JP 2013513109A5
Authority
JP
Japan
Prior art keywords
sample
particles
fluid
flow
acoustic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012542118A
Other languages
English (en)
Japanese (ja)
Other versions
JP5887275B2 (ja
JP2013513109A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/058242 external-priority patent/WO2011068764A2/en
Publication of JP2013513109A publication Critical patent/JP2013513109A/ja
Publication of JP2013513109A5 publication Critical patent/JP2013513109A5/ja
Application granted granted Critical
Publication of JP5887275B2 publication Critical patent/JP5887275B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012542118A 2009-12-04 2010-11-29 アコースティックフローサイトメトリーのための装置、システム、方法、およびコンピュータ読み取り可能な媒体 Active JP5887275B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US26690709P 2009-12-04 2009-12-04
US61/266,907 2009-12-04
US30393810P 2010-02-12 2010-02-12
US61/303,938 2010-02-12
US35931010P 2010-06-28 2010-06-28
US61/359,310 2010-06-28
PCT/US2010/058242 WO2011068764A2 (en) 2009-12-04 2010-11-29 Apparatuses, systems, methods, and computer readable media for acoustic flow cytometry

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016025611A Division JP6336496B2 (ja) 2009-12-04 2016-02-15 アコースティックフローサイトメトリーのための装置、システム、方法、およびコンピュータ読み取り可能な媒体

Publications (3)

Publication Number Publication Date
JP2013513109A JP2013513109A (ja) 2013-04-18
JP2013513109A5 true JP2013513109A5 (https=) 2015-01-29
JP5887275B2 JP5887275B2 (ja) 2016-03-16

Family

ID=44081725

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012542118A Active JP5887275B2 (ja) 2009-12-04 2010-11-29 アコースティックフローサイトメトリーのための装置、システム、方法、およびコンピュータ読み取り可能な媒体
JP2016025611A Active JP6336496B2 (ja) 2009-12-04 2016-02-15 アコースティックフローサイトメトリーのための装置、システム、方法、およびコンピュータ読み取り可能な媒体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016025611A Active JP6336496B2 (ja) 2009-12-04 2016-02-15 アコースティックフローサイトメトリーのための装置、システム、方法、およびコンピュータ読み取り可能な媒体

Country Status (6)

Country Link
US (2) US20110134426A1 (https=)
EP (1) EP2507639B1 (https=)
JP (2) JP5887275B2 (https=)
CN (2) CN104330346B (https=)
AU (1) AU2010326180B2 (https=)
WO (1) WO2011068764A2 (https=)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7340957B2 (en) 2004-07-29 2008-03-11 Los Alamos National Security, Llc Ultrasonic analyte concentration and application in flow cytometry
US7835000B2 (en) 2006-11-03 2010-11-16 Los Alamos National Security, Llc System and method for measuring particles in a sample stream of a flow cytometer or the like
EP2664916B1 (en) 2007-04-02 2017-02-08 Acoustic Cytometry Systems, Inc. Method for manipulating a fluid medium within a flow cell using acoustic focusing
US8083068B2 (en) 2007-04-09 2011-12-27 Los Alamos National Security, Llc Apparatus for separating particles utilizing engineered acoustic contrast capture particles
US7837040B2 (en) * 2007-04-09 2010-11-23 Los Alamos National Security, Llc Acoustic concentration of particles in fluid flow
US8528406B2 (en) * 2007-10-24 2013-09-10 Los Alamos National Security, LLP Method for non-contact particle manipulation and control of particle spacing along an axis
US8263407B2 (en) * 2007-10-24 2012-09-11 Los Alamos National Security, Llc Method for non-contact particle manipulation and control of particle spacing along an axis
US20090156932A1 (en) 2007-12-13 2009-06-18 Board Of Trustees Of The University Of Arkansas Device and method for in vivo flow cytometry using the detection of photoacoustic waves
US9144383B2 (en) 2007-12-13 2015-09-29 The Board Of Trustees Of The University Of Arkansas Device and method for in vivo noninvasive magnetic manipulation of circulating objects in bioflows
US9451884B2 (en) 2007-12-13 2016-09-27 Board Of Trustees Of The University Of Arkansas Device and method for in vivo detection of clots within circulatory vessels
US8266951B2 (en) 2007-12-19 2012-09-18 Los Alamos National Security, Llc Particle analysis in an acoustic cytometer
US8714014B2 (en) 2008-01-16 2014-05-06 Life Technologies Corporation System and method for acoustic focusing hardware and implementations
WO2010132474A2 (en) * 2009-05-11 2010-11-18 Stc.Unm Stable elastomeric negative acoustic contrast particles and their use in acoustic radiation fields
CN104330346B (zh) * 2009-12-04 2017-04-12 生命技术公司 用于声学流式细胞计量术的方法
JP5437148B2 (ja) * 2010-04-23 2014-03-12 ベイバイオサイエンス株式会社 フローサイトメータおよびセルソータ
CN102933948B (zh) * 2010-05-05 2015-06-24 贝克曼考尔特生物医学有限责任公司 诊断系统和部件
WO2012098287A1 (en) * 2011-01-19 2012-07-26 Teknologian Tutkimuskeskus Vtt Method and system for determining particle size information
SG10201601482YA (en) 2011-03-03 2016-04-28 Life Technologies Corp Sampling Probes, Systems, Apparatuses, And Methods
USD698038S1 (en) 2011-03-03 2014-01-21 Life Technologies Corporation Plate loader
EP2724160A2 (en) * 2011-06-27 2014-04-30 Life Technologies Corporation Acoustic cytometry methods and protocols
EP2594334A1 (en) 2011-11-21 2013-05-22 Drive O2 Sample vial for digital holographic analysis of a liquid cell sample
CN108107197B (zh) 2011-07-19 2020-05-08 奥维茨奥成像系统公司 用于检测和/或分类细胞样品中的癌细胞的方法和系统
US9656263B2 (en) 2011-09-28 2017-05-23 Acousort Ab System and method to separate cells and/or particles
EP2626686A1 (en) * 2012-02-13 2013-08-14 Ovizio Imaging Systems NV/SA Flow cytometer with digital holographic microscope
US10967298B2 (en) 2012-03-15 2021-04-06 Flodesign Sonics, Inc. Driver and control for variable impedence load
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
EP2864762A4 (en) * 2012-06-21 2016-01-20 Stc Unm SPATIALLY CORRELATED COLLECTION OF MULTIPLE SAMPLES TREATED WITH A LINE-FOCUSED LIGHT SOURCE
EP2898310B1 (en) 2012-09-20 2019-05-01 Ovizio Imaging Systems NV/SA Digital holographic microscope with fluid systems
WO2014052449A1 (en) 2012-09-25 2014-04-03 The Board Of Trustees Of The University Of Arkansas Device and method for in vivo photoacoustic diagnosis and photothermal purging of infected blood
CN110579435B (zh) * 2012-10-15 2023-09-26 纳诺赛莱克特生物医药股份有限公司 颗粒分选的系统、设备和方法
US10371622B2 (en) 2013-03-14 2019-08-06 Inguran, Llc Device for high throughput sperm sorting
US10662408B2 (en) 2013-03-14 2020-05-26 Inguran, Llc Methods for high throughput sperm sorting
US9757726B2 (en) 2013-03-14 2017-09-12 Inguran, Llc System for high throughput sperm sorting
BR112015026234B1 (pt) * 2013-04-15 2022-02-08 Becton, Dickinson And Company Dispositivo de separação de fluido biológico e sistema de separação de fluido biológico
CA3005826C (en) 2013-04-15 2021-11-23 Becton, Dickinson And Company Biological fluid collection device and biological fluid separation and testing system
US9645080B2 (en) * 2013-04-16 2017-05-09 University Of Washington Systems, devices, and methods for separating, concentrating, and/or differentiating between cells from a cell sample
CN105579828B (zh) 2013-05-28 2020-02-14 克莫麦特公司 图像式细胞仪
US10126220B2 (en) * 2013-07-22 2018-11-13 National Oilwell Varco, L.P. Systems and methods for determining specific gravity and minerological properties of a particle
EP3042178B1 (en) * 2013-09-05 2019-08-21 Bio-rad Laboratories, Inc. Method of isolating a particle from a fluid sample
US9920313B2 (en) * 2013-10-21 2018-03-20 Biomet Biologics, Llc Cell washing device using a wave
WO2015105955A1 (en) 2014-01-08 2015-07-16 Flodesign Sonics, Inc. Acoustophoresis device with dual acoustophoretic chamber
US9377400B2 (en) * 2014-03-31 2016-06-28 Redshift Systems Corporation Motion modulation fluidic analyzer system
SG11201701581YA (en) 2014-08-28 2017-04-27 Sysmex Corp Particle imaging apparatus and particle imaging method
CN106796169B (zh) * 2014-10-01 2021-01-15 水光科技私人有限公司 探测流体中颗粒的传感器
KR102210343B1 (ko) 2014-10-24 2021-02-02 라이프 테크놀로지스 코포레이션 음향 침강식 액체-액체 샘플 정제 시스템
JP6646298B2 (ja) * 2014-12-16 2020-02-14 国立大学法人 東京大学 ロープ状構造体の製造方法
US10900885B2 (en) * 2014-12-19 2021-01-26 Captl Llc Flow cytometry using hydrodynamically planar flow
EP3240472B1 (en) * 2014-12-31 2023-07-26 Bioventures, LLC. Devices and methods for fractionated photoacoustic flow cytometry
JP6607945B2 (ja) * 2015-01-12 2019-11-20 インストゥルメンテーション ラボラトリー カンパニー 生物医学的な感知及び検出のための粒子を含む溶液中の粒子の空間的な分離
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11021699B2 (en) 2015-04-29 2021-06-01 FioDesign Sonics, Inc. Separation using angled acoustic waves
WO2016181968A1 (ja) * 2015-05-13 2016-11-17 株式会社エアレックス パーティクル制御方法
JP6713730B2 (ja) 2015-05-20 2020-06-24 シスメックス株式会社 細胞検出装置および細胞検出方法
US10036698B2 (en) 2015-06-19 2018-07-31 Captl Llc Time-sequential cytometry
US11474085B2 (en) 2015-07-28 2022-10-18 Flodesign Sonics, Inc. Expanded bed affinity selection
US11459540B2 (en) 2015-07-28 2022-10-04 Flodesign Sonics, Inc. Expanded bed affinity selection
WO2017054839A1 (en) * 2015-09-28 2017-04-06 Siemens Healthcare Gmbh A technique for aligning a non-spherical biological entity in a flow cell
US10648900B2 (en) * 2015-12-23 2020-05-12 Becton, Dickinson And Company Multi-color flow cytometric analysis of samples with low cell numbers
EP3362777B1 (de) * 2015-12-23 2023-02-22 Siemens Healthcare GmbH Fliesszelle zur analyse von partikeln in einer zu untersuchenden flüssigkeit, verfahren und verwendung
EP3196631A1 (en) 2016-01-19 2017-07-26 Ovizio Imaging Systems NV/SA Digital holographic microscope with electro-fluidic system, said electro-fluidic system and methods of use
US11085035B2 (en) 2016-05-03 2021-08-10 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
FR3051556A1 (fr) * 2016-05-18 2017-11-24 Biocytex Utilisation de marqueurs fluorescents pour la detection de cible biologique dans un echantillon
CN109416314A (zh) * 2016-07-01 2019-03-01 生命技术公司 用于浓缩颗粒的方法、系统和装置
CA3032340A1 (en) * 2016-08-02 2018-02-08 Imec Vzw Method and arrangement for focusing objects in a flow
EP3300804B1 (en) * 2016-09-30 2020-04-08 ARKRAY, Inc. Method for separating particles, separation apparatus, and separation system
WO2018075830A1 (en) 2016-10-19 2018-04-26 Flodesign Sonics, Inc. Affinity cell extraction by acoustics
EP4390369A3 (en) 2016-11-19 2025-01-01 Cytek Biosciences, Inc. Flow cytometry systems with stepper flow control valve
US10436697B2 (en) 2016-11-19 2019-10-08 Cytek Biosciences, Inc. Flow cytometery system with fluidics control system
CN106556561A (zh) * 2016-11-28 2017-04-05 中国科学院苏州生物医学工程技术研究所 一种流体粒子运动控制装置
CN106872339A (zh) * 2017-01-10 2017-06-20 中国科学院苏州生物医学工程技术研究所 一种粒子排序方法及其装置和用途
CN110506201B (zh) * 2017-02-10 2022-11-29 东曹株式会社 粒子检测装置和粒子检测方法
JP7187474B2 (ja) 2017-03-31 2022-12-12 ライフ テクノロジーズ コーポレーション フローサイトメトリーを撮像するための装置、システム、および方法
CN107202773B (zh) * 2017-06-01 2019-07-05 重庆大学 一种利用聚苯乙烯球的细胞周期散射光强模型建立方法
EP3697294B1 (en) 2017-10-16 2023-12-06 Massachusetts Institute Of Technology System and method for non-invasive hematological measurements
DE102017126128A1 (de) 2017-11-08 2019-05-09 Endress+Hauser SE+Co. KG System und Verfahren zur ortsaufgelösten Bestimmung von zumindest einer physikalischen oder chemischen Prozessgröße
KR102439221B1 (ko) 2017-12-14 2022-09-01 프로디자인 소닉스, 인크. 음향 트랜스듀서 구동기 및 제어기
CN109946217B (zh) * 2017-12-21 2021-08-24 深圳先进技术研究院 一种声驱动的流式细胞检测装置
WO2019119368A1 (zh) * 2017-12-21 2019-06-27 深圳先进技术研究院 一种声驱动的流式细胞检测装置
CN108120665A (zh) * 2017-12-28 2018-06-05 无锡奥芬光电科技有限公司 单色结构光检查微小颗粒的方法及设备
CN108444897B (zh) * 2018-03-06 2021-04-13 山东大学 基于光片照明与鞘流技术的免标记微流控细胞仪及方法
US11698364B2 (en) 2018-06-27 2023-07-11 University Of Washington Real-time cell-surface marker detection
WO2020091866A1 (en) * 2018-10-30 2020-05-07 Becton, Dickinson And Company Particle sorting module with alignment window, systems and methods of use thereof
CN109540771B (zh) * 2018-12-18 2020-12-08 武汉大学 一种精准分选白细胞亚型的声光微流控芯片及其分选方法
US11788965B2 (en) * 2019-02-21 2023-10-17 Arizona Board Of Regents On Behalf Of Arizona State University Folic acid functionalized copper sulfide nanoparticles for the detection of ovarian cancer cells in flow
ES2956224T3 (es) * 2019-04-18 2023-12-15 Fundacio Inst De Ciencies Fotòniques Aparato fluídico para el interrogatorio óptico de microorganismos individuales
AU2020273451A1 (en) * 2019-05-15 2021-11-18 Flodesign Sonics, Inc. Acoustic edge effect
EP4529839A3 (en) 2019-07-24 2025-04-16 Massachusetts Institute of Technology Finger inserts for a nailfold imaging device
JP7729538B2 (ja) * 2019-12-29 2025-08-26 アプライド セルズ インク 生物学的実体を分離するための方法および装置
WO2021242983A1 (en) 2020-05-28 2021-12-02 Leuko Labs, Inc. A method to detect white blood cells and/or white blood cell subtypes form non-invasive capillary videos
US12399104B2 (en) 2020-06-03 2025-08-26 Kinetic River Corp. Configurable particle analyzer apparatuses and methods
JP7042301B2 (ja) * 2020-06-04 2022-03-25 シスメックス株式会社 細胞検出方法
KR20240029728A (ko) * 2020-11-25 2024-03-06 실리스, 인크. 개인 맞춤형 약 및 약물 개발에 사용하기 위한 미세-유기구체
EP4086607B1 (en) * 2021-05-07 2024-12-04 Deutsches Elektronen-Synchrotron DESY Device and system for bunching of sample particles
US12584902B2 (en) 2023-12-10 2026-03-24 Instrumentation Laboratory Company Acoustic separation of a test sample
WO2025264676A1 (en) * 2024-06-17 2025-12-26 Lumacyte, Inc. Apparatus, systems, and methods of analyzing biological particles
CN119101655A (zh) * 2024-10-09 2024-12-10 上海交通大学 一种基于单波束聚焦声场三维空间捕获细胞方法

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284412A (en) * 1979-07-13 1981-08-18 Ortho Diagnostics, Inc. Method and apparatus for automated identification and enumeration of specified blood cell subclasses
US4298836A (en) * 1979-11-23 1981-11-03 Coulter Electronics, Inc. Particle shape determination
JPS61153546A (ja) * 1984-12-26 1986-07-12 Canon Inc 粒子解析装置
JPS61159135A (ja) * 1984-12-31 1986-07-18 Canon Inc 粒子解析装置
JPS62207933A (ja) * 1986-03-08 1987-09-12 Canon Inc 粒子解析装置
US4786165A (en) * 1986-07-10 1988-11-22 Toa Medical Electronics Co., Ltd. Flow cytometry and apparatus therefor
JPH0449573Y2 (https=) * 1987-08-28 1992-11-20
JPH0277636A (ja) * 1988-09-13 1990-03-16 Canon Inc 粒子測定装置
JP3052665B2 (ja) * 1993-01-26 2000-06-19 株式会社日立製作所 フローセル装置
JPH07270301A (ja) * 1994-03-31 1995-10-20 Hitachi Ltd フロー式粒子画像解析方法およびその装置
JP3375203B2 (ja) * 1994-08-08 2003-02-10 シスメックス株式会社 細胞分析装置
JPH08297121A (ja) * 1995-04-26 1996-11-12 Hitachi Ltd 粒子分析装置
JPH09126989A (ja) * 1995-11-07 1997-05-16 Hitachi Ltd フロー式粒子画像解析装置
US5895869A (en) * 1995-11-17 1999-04-20 Mwi, Inc. Method and apparatus for analyzing particulate matter
GB9707096D0 (en) * 1997-04-08 1997-05-28 Smithkline Beecham Plc Novel device
US6074879A (en) * 1997-06-23 2000-06-13 Bayer Corporation Synthetic polymer particles for use as standards and calibrators in flow cytometry
US5880474A (en) * 1997-08-29 1999-03-09 Becton Dickinson And Company Multi-illumination-source flow particle analyzer with inter-location emissions crosstalk cancelation
US5895764A (en) * 1997-11-24 1999-04-20 University Of New Mexico Controlled sheath flow injection cytometry
US6067157A (en) * 1998-10-09 2000-05-23 University Of Washington Dual large angle light scattering detection
US6473171B1 (en) * 1999-01-15 2002-10-29 Coors Brewing Company Biocompatible apparatus for ultrasensitive and rapid detection of contaminants in liquids
US6249341B1 (en) * 1999-01-25 2001-06-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6890487B1 (en) * 1999-09-30 2005-05-10 Science & Technology Corporation ©UNM Flow cytometry for high throughput screening
US6263745B1 (en) * 1999-12-03 2001-07-24 Xy, Inc. Flow cytometer nozzle and flow cytometer sample handling methods
WO2002061112A2 (en) * 2001-01-29 2002-08-08 The University Of Tennessee Research Corporation Methods for detection of incorporation of a nucleotide onto a nucleic acid primer
US6467350B1 (en) * 2001-03-15 2002-10-22 The Regents Of The University Of California Cylindrical acoustic levitator/concentrator
JP2004535572A (ja) * 2001-06-13 2004-11-25 ケニス エフ. ウーヘンハイマー, 自動化流体操作システムおよび方法
US20030110840A1 (en) * 2001-07-24 2003-06-19 Arriaga Edgar A. Systems and methods for detecting a particle
US7201875B2 (en) * 2002-09-27 2007-04-10 Becton Dickinson And Company Fixed mounted sorting cuvette with user replaceable nozzle
US7340957B2 (en) * 2004-07-29 2008-03-11 Los Alamos National Security, Llc Ultrasonic analyte concentration and application in flow cytometry
EP2664916B1 (en) * 2007-04-02 2017-02-08 Acoustic Cytometry Systems, Inc. Method for manipulating a fluid medium within a flow cell using acoustic focusing
US7837040B2 (en) * 2007-04-09 2010-11-23 Los Alamos National Security, Llc Acoustic concentration of particles in fluid flow
US8083068B2 (en) * 2007-04-09 2011-12-27 Los Alamos National Security, Llc Apparatus for separating particles utilizing engineered acoustic contrast capture particles
US8266951B2 (en) * 2007-12-19 2012-09-18 Los Alamos National Security, Llc Particle analysis in an acoustic cytometer
US8714014B2 (en) * 2008-01-16 2014-05-06 Life Technologies Corporation System and method for acoustic focusing hardware and implementations
US20100009333A1 (en) * 2008-07-08 2010-01-14 Beckman Coulter, Inc. Methods for Acoustic Particle Focusing in Biological Sample Analyzers
CN104330346B (zh) * 2009-12-04 2017-04-12 生命技术公司 用于声学流式细胞计量术的方法

Similar Documents

Publication Publication Date Title
JP6336496B2 (ja) アコースティックフローサイトメトリーのための装置、システム、方法、およびコンピュータ読み取り可能な媒体
JP2013513109A5 (https=)
US12188856B2 (en) Particle analyzing systems and methods using acoustic radiation pressure
JP2009520198A (ja) 少なくとも2つの細胞集団を区別する方法及び応用
AU2015224429B2 (en) Apparatuses, systems, methods, and computer readable media for acoustic flow cytometry