JP2013511530A5 - - Google Patents
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- JP2013511530A5 JP2013511530A5 JP2012540005A JP2012540005A JP2013511530A5 JP 2013511530 A5 JP2013511530 A5 JP 2013511530A5 JP 2012540005 A JP2012540005 A JP 2012540005A JP 2012540005 A JP2012540005 A JP 2012540005A JP 2013511530 A5 JP2013511530 A5 JP 2013511530A5
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- JP
- Japan
- Prior art keywords
- group
- amino acid
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- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000001413 amino acids Chemical class 0.000 claims description 74
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 66
- 239000000203 mixture Substances 0.000 claims description 26
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 21
- 208000016604 Lyme disease Diseases 0.000 claims description 18
- 241000589968 Borrelia Species 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 14
- 239000000427 antigen Substances 0.000 claims description 10
- 102000036639 antigens Human genes 0.000 claims description 10
- 108091007433 antigens Proteins 0.000 claims description 10
- 101800001415 Bri23 peptide Proteins 0.000 claims description 8
- 102400000107 C-terminal peptide Human genes 0.000 claims description 8
- 101800000655 C-terminal peptide Proteins 0.000 claims description 8
- 230000015572 biosynthetic process Effects 0.000 claims description 8
- 239000007787 solid Substances 0.000 claims description 7
- 239000012634 fragment Substances 0.000 claims description 6
- 108010090804 Streptavidin Proteins 0.000 claims description 5
- 238000003556 assay Methods 0.000 claims description 4
- 239000011324 bead Substances 0.000 claims description 4
- 239000003153 chemical reaction reagent Substances 0.000 claims description 4
- 238000002372 labelling Methods 0.000 claims description 4
- 101800001693 R-peptide Proteins 0.000 claims description 3
- 238000004458 analytical method Methods 0.000 claims description 3
- 239000003446 ligand Substances 0.000 claims description 3
- 241000589969 Borreliella burgdorferi Species 0.000 claims description 2
- 238000012286 ELISA Assay Methods 0.000 claims description 2
- 238000007818 agglutination assay Methods 0.000 claims description 2
- 210000004369 blood Anatomy 0.000 claims description 2
- 239000008280 blood Substances 0.000 claims description 2
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 2
- 238000003018 immunoassay Methods 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims description 2
- 210000003296 saliva Anatomy 0.000 claims description 2
- 210000002966 serum Anatomy 0.000 claims description 2
- 241000894007 species Species 0.000 claims description 2
- 210000002700 urine Anatomy 0.000 claims description 2
- 235000001014 amino acid Nutrition 0.000 claims 16
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 4
- 108090001008 Avidin Proteins 0.000 claims 3
- 102000007562 Serum Albumin Human genes 0.000 claims 2
- 108010071390 Serum Albumin Proteins 0.000 claims 2
- 229960002685 biotin Drugs 0.000 claims 2
- 235000020958 biotin Nutrition 0.000 claims 2
- 239000011616 biotin Substances 0.000 claims 2
- 241000282465 Canis Species 0.000 claims 1
- 101710120037 Toxin CcdB Proteins 0.000 claims 1
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 1
- 235000018102 proteins Nutrition 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- -1 Q and E Chemical class 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26209909P | 2009-11-17 | 2009-11-17 | |
| US61/262,099 | 2009-11-17 | ||
| PCT/US2010/057053 WO2011063003A2 (en) | 2009-11-17 | 2010-11-17 | Peptides and methods for the detection of lyme disease antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013511530A JP2013511530A (ja) | 2013-04-04 |
| JP2013511530A5 true JP2013511530A5 (https=) | 2013-12-26 |
Family
ID=44060312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540005A Pending JP2013511530A (ja) | 2009-11-17 | 2010-11-17 | ライム病抗体の検出のためのペプチドおよび方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8568989B2 (https=) |
| EP (1) | EP2501719B1 (https=) |
| JP (1) | JP2013511530A (https=) |
| KR (1) | KR20120096932A (https=) |
| CN (1) | CN102791727A (https=) |
| AU (1) | AU2010322085B2 (https=) |
| CA (1) | CA2781110C (https=) |
| WO (1) | WO2011063003A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8758772B2 (en) | 2011-11-04 | 2014-06-24 | Abaxis, Inc. | Peptides and methods for the detection of lyme disease antibodies |
| FI3489685T3 (fi) | 2011-11-21 | 2023-12-21 | Zoetis Services Llc | Signaalin vahvistaminen lateraalivirtaus- ja vastaavissa immunomäärityksissä |
| JP2013164414A (ja) * | 2012-01-13 | 2013-08-22 | Nippon Meat Packers Inc | 抗菌ペプチドを用いた微生物の検出方法及び検出用キット |
| US9194870B2 (en) | 2014-01-21 | 2015-11-24 | Abaxis, Inc. | Peptides, devices, and methods for the detection of Anaplasma antibodies |
| WO2015160834A1 (en) * | 2014-04-14 | 2015-10-22 | Abreos Biosciences, Inc. | Lateral flow immunoassay |
| TWI691716B (zh) | 2014-08-13 | 2020-04-21 | 美商艾巴希斯公司 | 電漿特異性結合搭配物檢定中之信號放大 |
| WO2016049148A1 (en) * | 2014-09-24 | 2016-03-31 | Wellstat Diagnostics, Llc | Compositions and methods for te diagnosis of lyme disease |
| CN104330555B (zh) * | 2014-10-22 | 2016-05-11 | 中国检验检疫科学研究院 | 检测伯氏疏螺旋体抗体的试纸、试纸制备方法及试剂盒 |
| CA2991532C (en) | 2015-08-04 | 2024-03-05 | Abaxis, Inc. | Signal amplification in solution-based plasmonic specific-binding partner assays |
| CN108351355A (zh) | 2015-08-27 | 2018-07-31 | 奎多公司 | 具有两个流体流动路径用于检测和区分两个或多个分析物的免疫分析测试设备 |
| CN105548577B (zh) * | 2016-02-04 | 2017-09-19 | 安徽医科大学 | 一种琥珀酰‑β‑环糊精修饰的莱姆病检测用蛋白质芯片及其制备与应用 |
| EP3252470B1 (en) | 2016-06-03 | 2020-07-29 | Te?ted Oy | A method and a solid support for detecting tick-borne microbes in a biological sample |
| USD800912S1 (en) | 2016-06-17 | 2017-10-24 | Abreos Biosciences, Inc. | Point-of-care diagnostic device |
| WO2018031887A1 (en) | 2016-08-12 | 2018-02-15 | Abreos Biosciences, Inc. | Detection and quantification of natalizumab |
| CN106432487A (zh) * | 2016-10-31 | 2017-02-22 | 杭州贝英福生物科技有限公司 | 一种伽氏疏螺旋体多克隆抗体及应用 |
| CN106397589A (zh) * | 2016-10-31 | 2017-02-15 | 杭州贝英福生物科技有限公司 | 一种狭义伯氏疏螺旋体多克隆抗体及应用 |
| CN118275398A (zh) | 2017-01-30 | 2024-07-02 | 硕腾服务有限责任公司 | 基于溶液的等离子体振子特异性结合配偶体测定和金属纳米结构 |
| JP7062803B1 (ja) * | 2021-03-31 | 2022-05-06 | 積水メディカル株式会社 | 抗薬物抗体測定方法 |
| EP4220166A1 (en) | 2022-02-01 | 2023-08-02 | Universitat Rovira I Virgili (URV) | In vitro method for detecting antibodies in a sample |
| US20260049986A1 (en) * | 2022-04-04 | 2026-02-19 | Antigen Discovery Inc. | Antigens for Detection of Early Lyme Disease |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4366246A (en) | 1977-11-08 | 1982-12-28 | Genentech, Inc. | Method for microbial polypeptide expression |
| US4888276A (en) | 1986-06-26 | 1989-12-19 | Minnesota Mining And Manufacturing Company | Method and composition for the diagnosis of Lyme disease |
| US4721617A (en) | 1986-08-14 | 1988-01-26 | Regents Of The University Of Minnesota | Vaccine against lyme disease |
| US5385826A (en) | 1989-04-21 | 1995-01-31 | Gundersen Medical Foundation, Ltd. | Diagnostic assay for lyme disease |
| DE4015911A1 (de) | 1989-09-19 | 1991-03-28 | Max Planck Gesellschaft | Impfstoff gegen die lyme-krankheit |
| US5187065A (en) | 1989-12-22 | 1993-02-16 | Schutzer Steven E | Method and materials for detecting lyme disease |
| CA2084413A1 (en) | 1990-06-15 | 1991-12-16 | Richard A. Flavell | Compositions and methods for the prevention and diagnosis of lyme disease |
| US5155022A (en) | 1991-02-08 | 1992-10-13 | Becton, Dickinson And Company | Assay for lyme disease |
| US5324630A (en) | 1991-06-28 | 1994-06-28 | The Regents Of The University Of California | Methods and compositions for diagnosing lyme disease |
| US6221363B1 (en) | 1991-07-11 | 2001-04-24 | Baxter Aktiengesellschaft | Vaccine for the prevention of lyme disease |
| WO1993003184A1 (en) | 1991-08-09 | 1993-02-18 | Mccann Associates, Inc. | Method for detecting lyme disease and composition |
| US5965702A (en) | 1991-10-21 | 1999-10-12 | Abbott Laboratories | Borrelia burgdorferi antigens and uses thereof |
| US5618533A (en) | 1992-02-11 | 1997-04-08 | Yale University | Flagellin-based polypeptides for the diagnosis of lyme disease |
| US5308753A (en) | 1992-02-20 | 1994-05-03 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Methods for purifying and detecting IGM antibodies |
| US5620862A (en) | 1993-11-24 | 1997-04-15 | University Of Connecticut | Methods for diagnosing early Lyme disease |
| US5932220A (en) | 1995-05-08 | 1999-08-03 | Board Of Regents University Of Texas System | Diagnostic tests for a new spirochete, Borrelia lonestari sp. nov. |
| EP1589109B1 (en) | 1996-02-21 | 2017-04-12 | Board of Regents, The University of Texas System | VMP-like sequences of pathogenic borrelia |
| US6716574B2 (en) | 1996-05-02 | 2004-04-06 | Dako A/S | Osp-C derived peptide fragments |
| US6902893B1 (en) | 1997-06-20 | 2005-06-07 | Gil H. Choi | Lyme disease vaccines |
| US6660274B2 (en) | 1997-06-30 | 2003-12-09 | The Administrators Of The Tulane Educational Fund | Surface antigens and proteins useful in compositions for the diagnosis and prevention of lyme disease |
| AU4654500A (en) | 1999-04-21 | 2000-11-02 | Boston Medical Center Corporation | Prevention, diagnosis and treatment of lyme disease |
| US6475492B1 (en) | 1999-04-28 | 2002-11-05 | The Administrators Of The Tulane Educational Fund | Peptides and assays for the diagnosis of lyme disease |
| US6665652B1 (en) | 1999-07-28 | 2003-12-16 | Richard B. Porwancher | Method of diagnosis of lyme disease |
| CA2446246A1 (en) | 2001-05-03 | 2002-11-14 | Immunetics, Inc. | Systems and methods for detection of analytes in biological fluids |
| US6838247B2 (en) | 2002-06-19 | 2005-01-04 | Bowen Research And Training | Test for lyme disease |
| WO2004058181A2 (en) | 2002-12-20 | 2004-07-15 | Board Of Regents, The University Of Texas System | Vmp-like sequences of pathogenic borrelia species and strains |
| US20060046310A1 (en) | 2004-08-25 | 2006-03-02 | Zong-Li Xia | Amplification method for solid phase immunoassays |
| US7390626B2 (en) | 2005-02-25 | 2008-06-24 | Immunosciences Lab., Inc. | Methods and kit for diagnosing tick borne illnesses |
| DE602006014120D1 (de) | 2005-03-29 | 2010-06-17 | Inverness Medical Switzerland | Kolloidale metallkonjugate |
| WO2007133623A2 (en) * | 2006-05-10 | 2007-11-22 | Biopeptides Corporation | Peptide diagnostic agent for lyme disease |
| US7776618B2 (en) | 2007-03-01 | 2010-08-17 | Church & Dwight Co., Inc. | Diagnostic detection device |
| CA2690904C (en) | 2007-06-27 | 2015-11-03 | Inbios International, Inc. | Lateral flow assay system and methods for its use |
| EP2058663A1 (en) | 2007-11-12 | 2009-05-13 | Euro-Diagnostica B.V. | Method for the immobilization of an analyte on a solid support |
| JP2009236685A (ja) | 2008-03-27 | 2009-10-15 | Sysmex Corp | クロマトグラフィー用試験具 |
-
2010
- 2010-11-17 EP EP10832113.4A patent/EP2501719B1/en active Active
- 2010-11-17 KR KR1020127015460A patent/KR20120096932A/ko not_active Ceased
- 2010-11-17 CN CN2010800616653A patent/CN102791727A/zh active Pending
- 2010-11-17 JP JP2012540005A patent/JP2013511530A/ja active Pending
- 2010-11-17 WO PCT/US2010/057053 patent/WO2011063003A2/en not_active Ceased
- 2010-11-17 CA CA2781110A patent/CA2781110C/en active Active
- 2010-11-17 US US12/948,209 patent/US8568989B2/en active Active
- 2010-11-17 AU AU2010322085A patent/AU2010322085B2/en active Active
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