JP2013511283A - 電解質の添加を伴う抽出発酵を用いたブタノールの生成方法 - Google Patents

電解質の添加を伴う抽出発酵を用いたブタノールの生成方法 Download PDF

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JP2013511283A
JP2013511283A JP2012540149A JP2012540149A JP2013511283A JP 2013511283 A JP2013511283 A JP 2013511283A JP 2012540149 A JP2012540149 A JP 2012540149A JP 2012540149 A JP2012540149 A JP 2012540149A JP 2013511283 A JP2013511283 A JP 2013511283A
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butanol
extractant
fermentation
electrolyte
fermentation medium
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Japanese (ja)
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マイケル・チャールズ・グラディ
ランジャーン・パトナーイク
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ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16Butanols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C07C29/86Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by liquid-liquid treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10Separation or concentration of fermentation products
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/26Processes using, or culture media containing, hydrocarbons
    • C12N1/28Processes using, or culture media containing, hydrocarbons aliphatic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2012540149A 2009-11-23 2010-11-23 電解質の添加を伴う抽出発酵を用いたブタノールの生成方法 Pending JP2013511283A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26351909P 2009-11-23 2009-11-23
US61/263,519 2009-11-23
PCT/US2010/057791 WO2011063391A1 (en) 2009-11-23 2010-11-23 Method for producing butanol using extractive fermentation with electrolyte addition

Publications (1)

Publication Number Publication Date
JP2013511283A true JP2013511283A (ja) 2013-04-04

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JP2012540149A Pending JP2013511283A (ja) 2009-11-23 2010-11-23 電解質の添加を伴う抽出発酵を用いたブタノールの生成方法

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Country Link
US (2) US8617861B2 (enExample)
EP (1) EP2504446A1 (enExample)
JP (1) JP2013511283A (enExample)
KR (1) KR20120115500A (enExample)
CN (1) CN102656272A (enExample)
AU (1) AU2010321564A1 (enExample)
BR (1) BR112012012219A2 (enExample)
CA (1) CA2779884A1 (enExample)
IN (1) IN2012DN03440A (enExample)
MX (1) MX2012005684A (enExample)
NZ (1) NZ599414A (enExample)
WO (1) WO2011063391A1 (enExample)
ZA (1) ZA201203653B (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8956850B2 (en) * 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
MX2011003313A (es) 2008-09-29 2011-06-16 Butamax Tm Advanced Biofuels Actividad enzimatica de fe-s heterologa aumentada en levadura.
CA2735690A1 (en) 2008-09-29 2010-04-01 Dennis Flint Identification and use of bacterial [2fe-2s] dihydroxy-acid dehydratases
KR20130027063A (ko) 2010-02-17 2013-03-14 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 Fe-s 클러스터 요구성 단백질의 활성 향상
NZ603291A (en) 2010-06-18 2015-01-30 Butamax Tm Advanced Biofuels Extraction solvents derived from oil for alcohol removal in extractive fermentation
BR112014013741A2 (pt) 2011-12-09 2017-06-13 Butamax Advanced Biofuels Llc métodos para remoção de um álcool, sistema para recuperar o álcool, composições e alimento
CN104321436A (zh) 2011-12-30 2015-01-28 布特马斯先进生物燃料有限责任公司 醇类的发酵生产
BR112014023603A8 (pt) 2012-03-23 2017-07-25 Butamax Advanced Biofuels Llc Método para produção de butanol e composição
CA2870567A1 (en) 2012-05-04 2013-11-07 Butamax Advanced Biofuels Llc Processes and systems for alcohol production and recovery
CN104350034B (zh) 2012-06-08 2018-07-31 Cj 第一制糖株式会社 可再生丙烯酸生产和自其制备的产物
US9605281B2 (en) 2012-09-12 2017-03-28 Butamax Advanced Biofuels Llc Processes and systems for the fermentative production of alcohols
EP2877440A1 (en) 2012-07-26 2015-06-03 Butamax Advanced Biofuels LLC Butanol purification
KR20150040359A (ko) 2012-08-10 2015-04-14 오피엑스 바이오테크놀로지스, 인크. 지방산 및 지방산 유도된 산물의 생산을 위한 미생물 및 방법
BR112015005439A8 (pt) * 2012-09-12 2022-01-11 Butamax Advanced Biofuels Llc Método para recuperar um produto alcoólico de um caldo de fermentação e sistema
US9109196B2 (en) 2012-09-12 2015-08-18 Butamax Advanced Biofuels Llc Processes and systems for the production of fermentation products
AU2013317963A1 (en) * 2012-09-21 2015-03-12 Butamax(Tm) Advanced Biofuels Llc A method for producing butanol using two-phase extractive fermentation and recyclable extractant compositions
WO2014052735A1 (en) * 2012-09-28 2014-04-03 Butamax Advanced Biofuels Llc Production of fermentation products
US20140142352A1 (en) * 2012-11-20 2014-05-22 Butamax Advanced Biofuels Llc Butanol purification
WO2014106107A2 (en) 2012-12-28 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Dhad variants for butanol production
WO2014105840A1 (en) 2012-12-31 2014-07-03 Butamax Advanced Biofuels Llc Fermentative production of alcohols
US9523104B2 (en) 2013-03-12 2016-12-20 Butamax Advanced Biofuels Llc Processes and systems for the production of alcohols
US20150057465A1 (en) 2013-03-15 2015-02-26 Opx Biotechnologies, Inc. Control of growth-induction-production phases
WO2014151190A1 (en) 2013-03-15 2014-09-25 Butamax Advanced Biofuels Llc Dhad variants and methods of screening
EP2970988A4 (en) * 2013-03-15 2016-12-07 Cargill Inc CONTROL OF PHASES OF GROWTH INDUCTION PRODUCTION
BR112015020685A2 (pt) 2013-03-15 2017-07-18 Butamax Advanced Biofuels Llc método para a recuperação do butanol, composição, métodos para a extração de álcool e de secagem
US9469584B2 (en) 2013-03-15 2016-10-18 Butamax Advanced Biofuels Llc Method for producing butanol using extractive fermentation
WO2014144210A2 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Competitive growth and/or production advantage for butanologen microorganism
US9663759B2 (en) 2013-07-03 2017-05-30 Butamax Advanced Biofuels Llc Partial adaptation for butanol production
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US10337038B2 (en) 2013-07-19 2019-07-02 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
JP2017513697A (ja) 2014-04-11 2017-06-01 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー 汚染軽減
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
MY195498A (en) 2015-06-10 2023-01-26 Ptt Global Chemical Public Co Ltd Novel method to produce acrylic acid with acetaldehyde as the main by-product
FR3039167B1 (fr) * 2015-07-23 2023-11-10 Afyren Procede d'extraction de metabolites fermentaires produits par fermentation anaerobie a partir de biomasse fermentescible
EP3577227A4 (en) 2017-02-02 2020-12-30 Cargill Inc. GENETICALLY MODIFIED CELLS PRODUCING C6-C10 FATTY ACID DERIVATIVES
FR3085960B1 (fr) * 2018-09-14 2020-11-27 Kyanos Biotechnologies Procede de culture d’un microorganisme d’interet et installation associee

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
WO2009086391A2 (en) * 2007-12-27 2009-07-09 Gevo, Inc. Recovery of higher alcohols from dilute aqueous solutions
WO2009134730A2 (en) * 2008-04-28 2009-11-05 E. I. Du Pont De Nemours And Company A butanol dehydrogenase enzyme from the bacterium achromobacter xylosoxidans

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4865973A (en) * 1985-09-13 1989-09-12 Queen's University At Kingston Process for extractive fermentation
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
RU2394913C2 (ru) 2005-10-26 2010-07-20 Е.И.Дюпон Де Немур Энд Компани Ферментативное получение четырехуглеродных спиртов
US8945899B2 (en) * 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
US8956850B2 (en) 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
US8962298B2 (en) * 2006-05-02 2015-02-24 Butamax Advanced Biofuels Llc Recombinant host cell comprising a diol dehydratase
US7541173B2 (en) * 2006-06-15 2009-06-02 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
NZ579780A (en) * 2007-04-18 2012-07-27 Butamax Advanced Biofuels Llc Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
ES2575413T3 (es) * 2007-12-20 2016-06-28 Butamax (Tm) Advanced Biofuels Llc Cetol-ácido reductoisomerasa que utiliza NADH
WO2009149270A2 (en) * 2008-06-04 2009-12-10 E. I. Du Pont De Nemours And Company A method for producing butanol using two-phase extractive fermentation
MX2011003313A (es) * 2008-09-29 2011-06-16 Butamax Tm Advanced Biofuels Actividad enzimatica de fe-s heterologa aumentada en levadura.
CA2735690A1 (en) 2008-09-29 2010-04-01 Dennis Flint Identification and use of bacterial [2fe-2s] dihydroxy-acid dehydratases
US20100120105A1 (en) 2008-10-27 2010-05-13 Butamax (Tm) Advanced Biofuels Llc Carbon pathway optimized production hosts for the production of isobutanol
CA2756538A1 (en) * 2009-04-13 2010-10-21 Butamax(Tm) Advanced Biofuels Llc Method for producing butanol using extractive fermentation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
WO2009086391A2 (en) * 2007-12-27 2009-07-09 Gevo, Inc. Recovery of higher alcohols from dilute aqueous solutions
WO2009134730A2 (en) * 2008-04-28 2009-11-05 E. I. Du Pont De Nemours And Company A butanol dehydrogenase enzyme from the bacterium achromobacter xylosoxidans

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN5013000917; MALINOWSKI JANUSZ J: 'SALT EFFECTS IN EXTRACTION OF ETHANOL, 1-BUTANOL AND ACETONE FROM AQUEOUS SOLUTIONS' AICHE JOURNAL V40 N9, 199409, P1459-1465 *

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US20140080189A1 (en) 2014-03-20
CN102656272A (zh) 2012-09-05
EP2504446A1 (en) 2012-10-03
WO2011063391A1 (en) 2011-05-26
KR20120115500A (ko) 2012-10-18
CA2779884A1 (en) 2011-05-26
AU2010321564A1 (en) 2012-05-10
US8969055B2 (en) 2015-03-03
IN2012DN03440A (enExample) 2015-10-23
BR112012012219A2 (pt) 2021-02-02
NZ599414A (en) 2014-08-29
MX2012005684A (es) 2012-06-19
ZA201203653B (en) 2013-08-28
US8617861B2 (en) 2013-12-31
US20110159558A1 (en) 2011-06-30

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