IN2012DN03440A - - Google Patents

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Publication number
IN2012DN03440A
IN2012DN03440A IN3440DEN2012A IN2012DN03440A IN 2012DN03440 A IN2012DN03440 A IN 2012DN03440A IN 3440DEN2012 A IN3440DEN2012 A IN 3440DEN2012A IN 2012DN03440 A IN2012DN03440 A IN 2012DN03440A
Authority
IN
India
Prior art keywords
butanol
fermentation medium
fermentation
electrolyte
salt
Prior art date
Application number
Inventor
Michael Charles Grady
Ranjan Patnaik
Original Assignee
Butamax Tm Advanced Biofuels
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Butamax Tm Advanced Biofuels filed Critical Butamax Tm Advanced Biofuels
Publication of IN2012DN03440A publication Critical patent/IN2012DN03440A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C07C29/86—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/26—Processes using, or culture media containing, hydrocarbons
    • C12N1/28—Processes using, or culture media containing, hydrocarbons aliphatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Abstract

A method for producing butanol through microbial fermentation, in which the butanol product is removed during the fermentation by extraction into a water-immiscible organic extractant in the presence of at least one electrolyte at a concentration at least sufficient to increase the butanol partition coefficient relative to that in the presence of the salt concentration of the basal fermentation medium, is provided. The electrolyte may comprise a salt which dissociates in the fermentation medium, or in the aqueous phase of a biphasic fermentation medium, to form free ions. Also provided is a method and composition for recovering butanol from a fermentation medium.
IN3440DEN2012 2009-11-23 2010-11-23 IN2012DN03440A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26351909P 2009-11-23 2009-11-23
PCT/US2010/057791 WO2011063391A1 (en) 2009-11-23 2010-11-23 Method for producing butanol using extractive fermentation with electrolyte addition

Publications (1)

Publication Number Publication Date
IN2012DN03440A true IN2012DN03440A (en) 2015-10-23

Family

ID=43821815

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3440DEN2012 IN2012DN03440A (en) 2009-11-23 2010-11-23

Country Status (13)

Country Link
US (2) US8617861B2 (en)
EP (1) EP2504446A1 (en)
JP (1) JP2013511283A (en)
KR (1) KR20120115500A (en)
CN (1) CN102656272A (en)
AU (1) AU2010321564A1 (en)
BR (1) BR112012012219A2 (en)
CA (1) CA2779884A1 (en)
IN (1) IN2012DN03440A (en)
MX (1) MX2012005684A (en)
NZ (1) NZ599414A (en)
WO (1) WO2011063391A1 (en)
ZA (1) ZA201203653B (en)

Families Citing this family (35)

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US8956850B2 (en) 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
ES2521675T3 (en) 2008-09-29 2014-11-13 Butamax Advanced Biofuels Llc Identification and use of [2Fe-2S] -dihydroxy acid-bacterial dehydratases
WO2010037111A1 (en) 2008-09-29 2010-04-01 Butamax™ Advanced Biofuels LLC INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST
WO2011103300A2 (en) 2010-02-17 2011-08-25 Butamax(Tm) Advanced Biofuels Llc Improving activity of fe-s cluster requiring proteins
CN103119172B (en) 2010-06-18 2016-05-11 布特马斯先进生物燃料有限责任公司 Extract in fermentation, remove for alcohol derive from oily extraction solvent
EP2788096A2 (en) 2011-12-09 2014-10-15 Butamax Advanced Biofuels LLC Process to remove product alcohols from fermentation broth
JP2015503350A (en) 2011-12-30 2015-02-02 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー Alcoholic fermentation production
US9689004B2 (en) 2012-03-23 2017-06-27 Butamax Advanced Biofuels Llc Acetate supplemention of medium for butanologens
CN104822820A (en) 2012-05-04 2015-08-05 布特马斯先进生物燃料有限责任公司 Processes and systems for alcohol production and recovery
WO2013185009A1 (en) 2012-06-08 2013-12-12 Metabolix, Inc. Renewable acrylic acid production and products made therefrom
US9605281B2 (en) 2012-09-12 2017-03-28 Butamax Advanced Biofuels Llc Processes and systems for the fermentative production of alcohols
CA2878966A1 (en) 2012-07-26 2014-01-30 Butamax Advanced Biofuels Llc Butanol purification
SG11201501013PA (en) 2012-08-10 2015-04-29 Opx Biotechnologies Inc Microorganisms and methods for the production of fatty acids and fatty acid derived products
US9109196B2 (en) 2012-09-12 2015-08-18 Butamax Advanced Biofuels Llc Processes and systems for the production of fermentation products
EP2895612A1 (en) * 2012-09-12 2015-07-22 Butamax Advanced Biofuels LLC Processes and systems for the production of fermentation products
CA2885427A1 (en) * 2012-09-21 2014-03-27 Butamax Advanced Biofuels Llc A method for producing butanol using two-phase extractive fermentation and recyclable extractant compositions
US20140093931A1 (en) * 2012-09-28 2014-04-03 Butamax Advanced Biofuels Llc Production of fermentation products
WO2014081848A1 (en) * 2012-11-20 2014-05-30 Butamax Advanced Biofuels Llc Butanol purification
WO2014106107A2 (en) 2012-12-28 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Dhad variants for butanol production
WO2014105840A1 (en) 2012-12-31 2014-07-03 Butamax Advanced Biofuels Llc Fermentative production of alcohols
WO2014159309A1 (en) 2013-03-12 2014-10-02 Butamax Advanced Biofuels Llc Processes and systems for the production of alcohols
WO2014151190A1 (en) 2013-03-15 2014-09-25 Butamax Advanced Biofuels Llc Dhad variants and methods of screening
US9469584B2 (en) 2013-03-15 2016-10-18 Butamax Advanced Biofuels Llc Method for producing butanol using extractive fermentation
BR112015020685A2 (en) 2013-03-15 2017-07-18 Butamax Advanced Biofuels Llc butanol recovery method, composition, alcohol extraction and drying methods
US9771602B2 (en) 2013-03-15 2017-09-26 Butamax Advanced Biofuels Llc Competitive growth and/or production advantage for butanologen microorganism
BR112015023472A2 (en) * 2013-03-15 2017-12-05 Cargill Inc method of production of a chemical, method of bioproduction of a chemical, genetically modified organism and product
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
US9663759B2 (en) 2013-07-03 2017-05-30 Butamax Advanced Biofuels Llc Partial adaptation for butanol production
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
JP6603658B2 (en) 2013-07-19 2019-11-06 カーギル インコーポレイテッド Microorganisms and methods for the production of fatty acids and fatty acid derivatives
MX2016013359A (en) 2014-04-11 2017-02-09 Butamax Advanced Biofuels Llc Contamination mitigation.
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
MY195498A (en) 2015-06-10 2023-01-26 Ptt Global Chemical Public Co Ltd Novel method to produce acrylic acid with acetaldehyde as the main by-product
FR3039167B1 (en) * 2015-07-23 2023-11-10 Afyren METHOD FOR EXTRACTION OF FERMENTARY METABOLITES PRODUCED BY ANAEROBIC FERMENTATION FROM FERMENTESCIBLE BIOMASS
JP2020506702A (en) 2017-02-02 2020-03-05 カーギル インコーポレイテッド Genetically modified cells producing C6-C10 fatty acid derivatives

Family Cites Families (17)

* Cited by examiner, † Cited by third party
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US4865973A (en) * 1985-09-13 1989-09-12 Queen's University At Kingston Process for extractive fermentation
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
MX359740B (en) 2005-10-26 2018-10-09 Du Pont Fermentive production of four carbon alcohols.
US8956850B2 (en) 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
US8962298B2 (en) 2006-05-02 2015-02-24 Butamax Advanced Biofuels Llc Recombinant host cell comprising a diol dehydratase
US7541173B2 (en) 2006-06-15 2009-06-02 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
KR101573775B1 (en) * 2007-04-18 2015-12-04 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 - fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
WO2009085953A2 (en) 2007-12-20 2009-07-09 E. I. Du Pont De Nemours And Company Ketol-acid reductoisomerase using nadh
JP2011514140A (en) 2007-12-27 2011-05-06 ジーヴォ，インコーポレイテッド Recovery of higher alcohols from low concentration aqueous solutions.
US8188250B2 (en) * 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
EP2657344B1 (en) * 2008-06-04 2016-04-27 Butamax (TM) Advanced Biofuels LLC Method for producing butanol using two-phase extractive fermentation
ES2521675T3 (en) 2008-09-29 2014-11-13 Butamax Advanced Biofuels Llc Identification and use of [2Fe-2S] -dihydroxy acid-bacterial dehydratases
WO2010037111A1 (en) 2008-09-29 2010-04-01 Butamax™ Advanced Biofuels LLC INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST
EP2350298A1 (en) 2008-10-27 2011-08-03 ButamaxTM Advanced Biofuels LLC Carbon pathway optimized production hosts for the production of isobutanol
CA2756538A1 (en) * 2009-04-13 2010-10-21 Butamax(Tm) Advanced Biofuels Llc Method for producing butanol using extractive fermentation

Also Published As

Publication number Publication date
JP2013511283A (en) 2013-04-04
WO2011063391A1 (en) 2011-05-26
EP2504446A1 (en) 2012-10-03
ZA201203653B (en) 2013-08-28
US20110159558A1 (en) 2011-06-30
KR20120115500A (en) 2012-10-18
US8969055B2 (en) 2015-03-03
MX2012005684A (en) 2012-06-19
CN102656272A (en) 2012-09-05
CA2779884A1 (en) 2011-05-26
US8617861B2 (en) 2013-12-31
BR112012012219A2 (en) 2021-02-02
AU2010321564A1 (en) 2012-05-10
NZ599414A (en) 2014-08-29
US20140080189A1 (en) 2014-03-20

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