JP2013511272A - 哺乳類様複合ｎ−グリカンを生成する酵母株 - Google Patents

哺乳類様複合ｎ−グリカンを生成する酵母株 Download PDF

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JP2013511272A
JP2013511272A JP2012539436A JP2012539436A JP2013511272A JP 2013511272 A JP2013511272 A JP 2013511272A JP 2012539436 A JP2012539436 A JP 2012539436A JP 2012539436 A JP2012539436 A JP 2012539436A JP 2013511272 A JP2013511272 A JP 2013511272A
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glcnac
nucleic acid
protein
cell
man
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スティーブン クリスチャン ヨゼフ ヘイセンス，
ヴァウテル フェルフェケン，
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オキシレイン ユーケー リミテッド
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    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
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    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01024—Alpha-mannosidase (3.2.1.24)
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01084—Glucan 1,3-alpha-glucosidase (3.2.1.84), i.e. mutanase
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01114—Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (3.2.1.114)

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JP2012539436A 2009-11-19 2010-11-19 哺乳類様複合ｎ−グリカンを生成する酵母株 Pending JP2013511272A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26282809P 2009-11-19 2009-11-19
US61/262,828 2009-11-19
PCT/IB2010/003154 WO2011061629A2 (en) 2009-11-19 2010-11-19 Yeast strains producing mammalian-like complex n-glycans

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JP2013511272A true JP2013511272A (ja) 2013-04-04
JP2013511272A5 JP2013511272A5 (https=) 2014-01-09

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US (3) US20130053550A1 (https=)
EP (1) EP2501805B1 (https=)
JP (1) JP2013511272A (https=)
KR (1) KR20130055555A (https=)
CN (1) CN102834509A (https=)
BR (1) BR112012011980A2 (https=)
CA (1) CA2781240A1 (https=)
DK (1) DK2501805T3 (https=)
WO (1) WO2011061629A2 (https=)

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WO2012042387A2 (en) 2010-09-29 2012-04-05 Oxyrane Uk Limited De-mannosylation of phosphorylated n-glycans
US9347050B2 (en) 2010-09-29 2016-05-24 Oxyrane Uk Limited Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated N-glycans and methods of facilitating mammalian cellular uptake of glycoproteins
BR112014015933A2 (pt) * 2011-12-30 2019-09-24 Oxyrane Uk Ltd métodos e materiais para reduzir a degradação das proteínas recombinantes
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KR102167388B1 (ko) * 2020-01-15 2020-10-19 코스맥스 주식회사 신규 로도스포리디움 토룰로이데스 균주 및 그 균주 배양액을 포함하는 화장료 조성물
CN119110849A (zh) * 2022-01-27 2024-12-10 二进国际(美国)有限公司 Thermothelomyces heterothallica的糖工程
CN116042562B (zh) * 2022-03-11 2023-10-20 山东恒鲁生物科技有限公司 重组酵母菌及其应用

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