JP2013510590A - 臓器を形成および／または分析するためのバイオリアクタ、システムおよび方法 - Google Patents

臓器を形成および／または分析するためのバイオリアクタ、システムおよび方法 Download PDF

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JP2013510590A
JP2013510590A JP2012539873A JP2012539873A JP2013510590A JP 2013510590 A JP2013510590 A JP 2013510590A JP 2012539873 A JP2012539873 A JP 2012539873A JP 2012539873 A JP2012539873 A JP 2012539873A JP 2013510590 A JP2013510590 A JP 2013510590A
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organ
tissue
less
bioreactor
growth
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JP2013510590A5 (enExample
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ソステック，ロン
コンシーリョ，ヨセフ
グリーン，デービット
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ハーバード バイオサイエンス インコーポレーテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/26—Constructional details, e.g. recesses, hinges flexible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/50—Means for positioning or orientating the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K19/00—Record carriers for use with machines and with at least a part designed to carry digital markings
    • G06K19/06—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
    • G06K19/06009—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code with optically detectable marking
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K19/00—Record carriers for use with machines and with at least a part designed to carry digital markings
    • G06K19/06—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
    • G06K19/06187—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code with magnetically detectable marking
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K19/00—Record carriers for use with machines and with at least a part designed to carry digital markings
    • G06K19/06—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
    • G06K19/067—Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards also with resonating or responding marks without active components

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Theoretical Computer Science (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2012539873A 2009-11-17 2010-11-17 臓器を形成および／または分析するためのバイオリアクタ、システムおよび方法 Pending JP2013510590A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26213009P 2009-11-17 2009-11-17
US61/262,130 2009-11-17
US29839310P 2010-01-26 2010-01-26
US61/298,393 2010-01-26
PCT/US2010/002995 WO2011062621A2 (en) 2009-11-17 2010-11-17 Bioreactors, systems, and methods for producing and/or analyzing organs

Publications (2)

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JP2013510590A true JP2013510590A (ja) 2013-03-28
JP2013510590A5 JP2013510590A5 (enExample) 2014-01-09

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US (1) US20130177972A1 (enExample)
EP (1) EP2501794A4 (enExample)
JP (1) JP2013510590A (enExample)
AU (1) AU2010322460B2 (enExample)
CA (1) CA2818514A1 (enExample)
RU (1) RU2012125263A (enExample)
WO (1) WO2011062621A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016005463A (ja) * 2013-11-11 2016-01-14 利仁 曽根 交換部品方法
JP6111510B1 (ja) * 2016-05-02 2017-04-12 インテグリカルチャー株式会社 成長誘導システム、成長誘導制御装置、成長誘導制御方法、および、成長誘導制御プログラム
JP2021511339A (ja) * 2018-01-19 2021-05-06 ユニバーシティ オブ メリーランド，ボルチモア 輸送中の人間の臓器を取り扱うための技術

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9901362B2 (en) * 2007-07-16 2018-02-27 Dune Medical Devices Ltd. Medical device and method for use in tissue characterization and treatment
US9757098B2 (en) 2007-07-16 2017-09-12 Dune Medical Devices Ltd. Medical device and method for use in tissue characterization and treatment
US9999353B2 (en) * 2007-07-16 2018-06-19 Dune Medical Devices Ltd. Medical device and method for use in tissue characterization and treatment
EP2535006A3 (en) 2007-07-16 2013-02-27 Dune Medical Devices Ltd. Medical device for tissue characterization and treatment
US8781201B2 (en) * 2009-03-04 2014-07-15 Robert E. Sandstrom Method of operating a pathology laboratory
US8507263B2 (en) 2009-08-07 2013-08-13 Maria Adelaide Asnaghi Rotating bioreactor
US9469671B2 (en) * 2011-09-03 2016-10-18 Therapeutic Proteins International, LLC Closed bioreactor
US10989362B2 (en) 2011-10-07 2021-04-27 Pall Technology Uk Limited Fluid processing control system and related methods
WO2013163358A1 (en) 2012-04-24 2013-10-31 Harvard Bioscience, Inc. Engineered tissue scaffolds and supports therefor
WO2014004746A2 (en) 2012-06-26 2014-01-03 Harvard Bioscience, Inc. Methods and compositions for promoting the structural integrity of scaffolds for tissue engineering
WO2014008408A1 (en) * 2012-07-03 2014-01-09 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Method and apparatus to detect lipid contents in tissues using ultrasound
WO2014042771A2 (en) 2012-07-28 2014-03-20 Harvard Bioscience, Inc. Analytical methods
JP6017219B2 (ja) * 2012-08-01 2016-10-26 オリンパス株式会社 蛍光観察装置および蛍光観察システム
EP3690028A1 (en) * 2012-09-04 2020-08-05 Anthrogenesis Corporation Methods of tissue generation
HK1217663A1 (zh) 2013-01-09 2017-01-20 Harvard Apparatus Regenerative Technology, Inc. 合成支架
EP2787069B1 (de) * 2013-04-04 2015-08-05 Universität Leipzig Verfahren und Vorrichtung zur Dezellularisierung von Organen und Geweben
JP2015000140A (ja) * 2013-06-13 2015-01-05 キヤノン株式会社 被検体情報取得装置
GB201310773D0 (en) * 2013-06-17 2013-07-31 Northwick Park Inst For Medcal Res Ltd Implant and method of producing an implant
JP2015030211A (ja) * 2013-08-04 2015-02-16 泰 金田 自然な方向にそって印刷する３次元印刷方法および３ｄプリンタ
US10447947B2 (en) * 2013-10-25 2019-10-15 The University Of Akron Multipurpose imaging and display system
DE102014205888B3 (de) * 2014-03-28 2015-05-28 Siemens Aktiengesellschaft Frequenzüberwachung von Gradientenpulsen bei der Magnetresonanz-Bildgebung
TWI518583B (zh) * 2014-04-18 2016-01-21 三緯國際立體列印科技股份有限公司 立體列印裝置及其列印異常偵測方法
EP3247281B1 (en) 2015-01-23 2020-12-02 The University of North Carolina at Chapel Hill Apparatuses, systems, and methods for preclinical ultrasound imaging of subjects
DE102015203537B3 (de) * 2015-02-27 2016-06-23 Celltool Gmbh Vorrichtung und Verfahren zur Überprüfung eines Materials für eine Transplantation
CN104970768B (zh) * 2015-05-11 2018-02-06 西南交通大学 一种半体内血液循环环境生物介入材料实验装置
CN106696292B (zh) * 2015-07-31 2019-03-05 三纬国际立体列印科技股份有限公司 立体打印装置
US9879216B2 (en) * 2015-12-10 2018-01-30 International Business Machines Corporation Infrared signal monitoring for cell cultures
TWI582885B (zh) * 2015-12-30 2017-05-11 國立中央大學 低溫製造組織工程用支架的平台結構及低溫製造組織工程用支架的製造方法
SG10201602102PA (en) * 2016-03-17 2017-10-30 Changi General Hospital Pte Ltd Lung simulation model
CA3027505A1 (en) 2016-06-15 2017-12-21 The General Hospital Corporation Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions
US10738272B2 (en) 2016-06-27 2020-08-11 General Electric Company Heating assembly for a bioreactor and an associated method thereof
WO2018013727A1 (en) 2016-07-12 2018-01-18 Deka Products Limited Partnership System and method for applying force to a device
US11254901B2 (en) 2016-07-12 2022-02-22 Deka Products Limited Partnership System and method for printing tissue
ES2842435T3 (es) 2016-07-22 2021-07-14 Eth Zuerich Conjunto de circuito de perfusión para la perfusión ex-vivo del hígado
CN115044471B (zh) 2016-08-27 2025-05-27 三维生物科技有限公司 生物反应器
US20190242896A1 (en) * 2016-09-02 2019-08-08 The University Of North Carolina At Chapel Hill System and method for noninvasively assessing bioengineered organs
US11299705B2 (en) 2016-11-07 2022-04-12 Deka Products Limited Partnership System and method for creating tissue
WO2018136739A1 (en) * 2017-01-21 2018-07-26 The Johns Hopkins University Tissue scaffold mold apparatus and use in making tissue engineered organs with hollow structures
US11529437B2 (en) * 2017-03-03 2022-12-20 Beijing Biosis Healing Biological Technology Co., Ltd. Biological tissue matrix material, preparation method therefor and use thereof in otological repair material
US10967578B2 (en) * 2017-07-11 2021-04-06 Daniel S. Clark 5D part growing machine with volumetric display technology
US11919246B2 (en) 2017-07-11 2024-03-05 Daniel S. Clark 5D part growing machine with volumetric display technology
US12297416B2 (en) 2017-07-12 2025-05-13 Deka Products Limited Partneship System and method for transferring tissue
US10570362B2 (en) 2017-07-12 2020-02-25 Deka Products Limited Partnership System and method for transferring tissue
WO2019051486A1 (en) * 2017-09-11 2019-03-14 3D Biotek, Llc LARGE SCALE BIOREACTOR
US11881119B2 (en) * 2017-12-06 2024-01-23 Cilag Gmbh International Modeling air leaks in lungs
EP3740067B1 (en) 2018-01-19 2024-11-06 ETH Zürich Perfusion loop assembly for an ex-vivo liver perfusion and a method for ex-vivo liver perfusion
WO2019148110A1 (en) * 2018-01-29 2019-08-01 Culture Biosciences, Inc. Methods for automated control of a fermentation system
EP3690020A4 (en) * 2018-03-19 2020-11-04 Tissuebynet Corporation MANUFACTURING DEVICE, MANUFACTURING SYSTEM, AND MANUFACTURING METHOD FOR CELL STRUCTURE
WO2019191299A1 (en) 2018-03-27 2019-10-03 San Diego State University In situ partially degradable separation interface for fabrication of complex near net shape objects by pressure assisted sintering
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
WO2020076894A2 (en) * 2018-10-09 2020-04-16 Telhan Orkan M Portable bioreactors and portable bioreactor systems for analyzing biofilm formation and degradation
ES1226226Y (es) * 2019-01-10 2019-05-31 Meta Cell Tech Sl Recipiente para tratamiento ex vivo de liquidos biologicos
US12024696B2 (en) * 2019-05-08 2024-07-02 Molecular Devices (Austria) GmbH System and method for organoid culture
WO2020231954A1 (en) 2019-05-10 2020-11-19 The University Of North Carolina At Chapel Hill Office Of Technology Commercialization Methods, systems, and computer readable media for generating images of microvasculature using ultrasound
US11834640B2 (en) * 2019-09-15 2023-12-05 Board Of Regents, The University Of Texas System Device and uses thereof for treating diabetes
WO2021231956A1 (en) * 2020-05-14 2021-11-18 North Carolina State University Fast automated approach for the derivation of acellular extracellular matrix scaffolds from tissues
DE102020118976A1 (de) * 2020-05-26 2021-12-16 Medical & Science Aktiengesellschaft Verfahren und Anordnung zur Bestimmung der flächig-räumlichen Temperaturverteilung im Mund- und Rachenraum eines Probanden
US12280540B2 (en) 2020-09-27 2025-04-22 San Diego State University Research Foundation In situ partially degradable separation interface for fabrication of complex near net shape objects by pressure assisted sintering
CA3253240A1 (en) * 2022-02-25 2023-08-31 Advanced Solutions Life Sciences, Llc BIOREACTOR ASSEMBLIES, PERFUSION BIOREACTOR SYSTEMS AND RELATED PROCESSES
US20230313111A1 (en) * 2022-04-04 2023-10-05 Arcology Inc. Dba Biosphere Bioreactors configured for uv sterilization, and methods of using uv sterilization in bioprocesses
US20250224513A1 (en) * 2022-04-11 2025-07-10 Institut National de la Santé et de la Recherche Médicale Method and apparatus for ultrasonic evaluation of an isolated organ
US12683032B2 (en) 2022-04-22 2026-07-14 International Business Machines Corporation Digital twin computer simulation using synchronization of body organ for determining compatibility
CN115322953A (zh) * 2022-08-15 2022-11-11 中国医学科学院生物医学工程研究所 一种用于细胞三维培养的高效接种方法及其应用
CN116012838B (zh) * 2022-12-30 2023-11-07 创芯国际生物科技(广州)有限公司 基于人工智能的类器官活性识别方法及系统
US12663314B2 (en) * 2023-05-08 2026-06-23 Lsi Industries, Inc. Infrared sensor assembly for receiving interchangeable lenses
US20260123867A1 (en) * 2023-06-14 2026-05-07 Organai Health, Inc. Apparatuses, systems, and methods for rapid on-site multiscale multimodal donor organ viability factor characterization
WO2026090226A1 (en) * 2024-10-23 2026-04-30 Arcology Inc. Dba Biosphere Uv-sterilizable bioprocess ports and systems using the same

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2001A (en) * 1841-03-12 Sawmill
US7027A (en) * 1850-01-15 Circulak
US3995444A (en) * 1974-11-08 1976-12-07 American Hospital Supply Corporation Organ perfusion system
JPH0291001A (ja) * 1988-09-28 1990-03-30 Olympus Optical Co Ltd 臓器保存装置
JPH02295901A (ja) * 1989-05-09 1990-12-06 Olympus Optical Co Ltd 臓器保存装置
JP2001516768A (ja) * 1997-09-23 2001-10-02 ハッサネイン，ワリード，エイチ． 臓器を維持するための組成物、方法及び装置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK85093D0 (da) * 1993-07-16 1993-07-16 Landsforeningen Til Kraeftens Method and apparatus for performing operations
US5586438A (en) * 1995-03-27 1996-12-24 Organ, Inc. Portable device for preserving organs by static storage or perfusion
US6582953B2 (en) * 1999-04-14 2003-06-24 Breonics, Inc. Organ chamber for exsanguinous metabolic support system
US7504201B2 (en) * 2004-04-05 2009-03-17 Organ Recovery Systems Method for perfusing an organ and for isolating cells from the organ
CN101001945B (zh) * 2004-06-04 2012-02-08 艾克塞勒雷克斯公司 一次性生物反应器系统及方法
ES2547139T3 (es) * 2005-08-26 2015-10-02 Regents Of The University Of Minnesota Descelularización y recelularización de órganos y tejidos
EP1988769A2 (en) * 2006-02-10 2008-11-12 Tengion, Inc. Bioreactor for organ reconstruction and augmentation
JP2010520127A (ja) * 2007-02-28 2010-06-10 エクセレレックス インク． フレキシブルコンテナ内の液体の重量測定
US8114664B2 (en) * 2007-07-12 2012-02-14 Worcester Polytechnic Institute Scalable wall bioreactor for culture of plant and animal tissues

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2001A (en) * 1841-03-12 Sawmill
US7027A (en) * 1850-01-15 Circulak
US3995444A (en) * 1974-11-08 1976-12-07 American Hospital Supply Corporation Organ perfusion system
JPH0291001A (ja) * 1988-09-28 1990-03-30 Olympus Optical Co Ltd 臓器保存装置
JPH02295901A (ja) * 1989-05-09 1990-12-06 Olympus Optical Co Ltd 臓器保存装置
JP2001516768A (ja) * 1997-09-23 2001-10-02 ハッサネイン，ワリード，エイチ． 臓器を維持するための組成物、方法及び装置

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JP6111510B1 (ja) * 2016-05-02 2017-04-12 インテグリカルチャー株式会社 成長誘導システム、成長誘導制御装置、成長誘導制御方法、および、成長誘導制御プログラム
WO2017191691A1 (ja) * 2016-05-02 2017-11-09 インテグリカルチャー株式会社 成長誘導システム、成長誘導制御装置、成長誘導制御方法、および、成長誘導制御プログラム
KR20180135488A (ko) 2016-05-02 2018-12-20 인테그리컬쳐 인코포레이티드 성장 유도 시스템, 성장 유도 제어 장치, 성장 유도 제어 방법, 및 성장 유도 제어 프로그램
DE112016006830T5 (de) 2016-05-02 2019-02-28 Integriculture Inc. System zur intelligenten induktion, steuervorrichtung zur alterungsinduktion, verfahren zur steuerung der alterungsinduktion und programm zur steuerung von alterungsinduktion
KR102170373B1 (ko) 2016-05-02 2020-10-27 인테그리컬쳐 인코포레이티드 성장 유도 시스템, 성장 유도 제어 장치, 성장 유도 제어 방법, 및 성장 유도 제어 프로그램
US11484879B2 (en) 2016-05-02 2022-11-01 Integriculture Inc. System for aging induction, control device for aging induction, method for controlling aging induction, and program for controlling aging induction
US11819846B2 (en) 2016-05-02 2023-11-21 Integriculture Inc. System for aging induction, control device for aging induction, method for controlling aging induction, and program for controlling aging induction
JP2021511339A (ja) * 2018-01-19 2021-05-06 ユニバーシティ オブ メリーランド，ボルチモア 輸送中の人間の臓器を取り扱うための技術

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US20130177972A1 (en) 2013-07-11
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AU2010322460B2 (en) 2015-05-28
WO2011062621A2 (en) 2011-05-26
EP2501794A4 (en) 2013-05-01
WO2011062621A3 (en) 2011-08-04
RU2012125263A (ru) 2013-12-27

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