JP2013510582A5 - - Google Patents
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- JP2013510582A5 JP2013510582A5 JP2012539009A JP2012539009A JP2013510582A5 JP 2013510582 A5 JP2013510582 A5 JP 2013510582A5 JP 2012539009 A JP2012539009 A JP 2012539009A JP 2012539009 A JP2012539009 A JP 2012539009A JP 2013510582 A5 JP2013510582 A5 JP 2013510582A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- mesenchymal stem
- stem cell
- cell according
- proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 102000004169 proteins and genes Human genes 0.000 claims 36
- 108090000623 proteins and genes Proteins 0.000 claims 36
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 31
- 238000000034 method Methods 0.000 claims 12
- 210000004027 cell Anatomy 0.000 claims 6
- 239000002609 medium Substances 0.000 claims 5
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 4
- 239000012091 fetal bovine serum Substances 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 3
- 210000002966 serum Anatomy 0.000 claims 3
- 230000001225 therapeutic effect Effects 0.000 claims 3
- 102000010565 Apoptosis Regulatory Proteins Human genes 0.000 claims 2
- 108010063104 Apoptosis Regulatory Proteins Proteins 0.000 claims 2
- 230000033115 angiogenesis Effects 0.000 claims 2
- 230000003110 anti-inflammatory effect Effects 0.000 claims 2
- 230000021164 cell adhesion Effects 0.000 claims 2
- 230000011712 cell development Effects 0.000 claims 2
- 230000010261 cell growth Effects 0.000 claims 2
- 230000011132 hemopoiesis Effects 0.000 claims 2
- 230000004614 tumor growth Effects 0.000 claims 2
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 claims 1
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 claims 1
- 102100027217 CD82 antigen Human genes 0.000 claims 1
- 101000922348 Homo sapiens C-X-C chemokine receptor type 4 Proteins 0.000 claims 1
- 101000914469 Homo sapiens CD82 antigen Proteins 0.000 claims 1
- 101001078133 Homo sapiens Integrin alpha-2 Proteins 0.000 claims 1
- 102100025305 Integrin alpha-2 Human genes 0.000 claims 1
- 108090001007 Interleukin-8 Proteins 0.000 claims 1
- 102100030511 Stanniocalcin-1 Human genes 0.000 claims 1
- 101710142157 Stanniocalcin-1 Proteins 0.000 claims 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 1
- 102100032807 Tumor necrosis factor-inducible gene 6 protein Human genes 0.000 claims 1
- 101710169430 Tumor necrosis factor-inducible gene 6 protein Proteins 0.000 claims 1
- 230000006907 apoptotic process Effects 0.000 claims 1
- 230000000712 assembly Effects 0.000 claims 1
- 238000000429 assembly Methods 0.000 claims 1
- 230000023549 cell-cell signaling Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 239000002356 single layer Substances 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26055909P | 2009-11-12 | 2009-11-12 | |
| US61/260,559 | 2009-11-12 | ||
| PCT/US2010/056502 WO2011060244A1 (en) | 2009-11-12 | 2010-11-12 | Spheroidal aggregates of mesenchymal stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013510582A JP2013510582A (ja) | 2013-03-28 |
| JP2013510582A5 true JP2013510582A5 (cg-RX-API-DMAC7.html) | 2014-01-09 |
Family
ID=43992060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012539009A Pending JP2013510582A (ja) | 2009-11-12 | 2010-11-12 | 間葉幹細胞の球状集合体 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20120219572A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2013510582A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011060244A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110223138A1 (en) * | 2009-12-17 | 2011-09-15 | Prockop Darwin J | Mesenchymal stem cells that express increased amounts of anti-apoptotic proteins |
| KR20140096105A (ko) * | 2011-11-04 | 2014-08-04 | 더 텍사스 에이 & 엠 유니버시티 시스템 | 중간엽 줄기 세포 및/또는 ｔｓｇ-6 단백질에 의한 이식 거부의 예방 및 치료 |
| EP2626369A1 (en) * | 2011-11-24 | 2013-08-14 | Fundació Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Engineered mesenchymal stem cells and their therapeutic use |
| US20150238532A1 (en) * | 2012-07-25 | 2015-08-27 | Albert Einstein College Of Medicine Of Yeshiva University | Methods to isolate human mesenchymal stem cells |
| EP2908910A4 (en) * | 2012-10-17 | 2016-06-29 | Texas A & M Univ Sys | TREATMENT OF BRAIN DAMAGE OR TRAUMA WITH TSG-6 PROTEIN |
| WO2014066122A1 (en) * | 2012-10-24 | 2014-05-01 | The Texas A&M University System | Treatment of tumors with activated mesenchymal stem cells |
| EP3446708A1 (en) * | 2012-12-24 | 2019-02-27 | Cell Ideas Pty Ltd. | Vaccines for the treatment of cancer and compositions for enhancing vaccine efficacy |
| KR102161726B1 (ko) | 2013-04-12 | 2020-10-06 | 사베리오 라프란체스카 | 이식용 장기의 개선 |
| US9790465B2 (en) | 2013-04-30 | 2017-10-17 | Corning Incorporated | Spheroid cell culture well article and methods thereof |
| US10208287B2 (en) * | 2014-05-01 | 2019-02-19 | Iheart Japan Corporation | CD82-positive cardiac progenitor cells |
| EP3142485B1 (en) * | 2014-05-12 | 2021-04-28 | Roosterbio, Inc. | Ready-to-print cells and integrated devices |
| WO2015199416A1 (ko) * | 2014-06-23 | 2015-12-30 | 단국대학교 천안캠퍼스 산학협력단 | 피부 또는 혈관 조직 손상 치료용 약학 조성물 및 이의 이용 |
| SG11201703500XA (en) | 2014-10-29 | 2017-05-30 | Corning Inc | Perfusion bioreactor platform |
| JP2017532971A (ja) | 2014-10-29 | 2017-11-09 | コーニング インコーポレイテッド | 細胞培養集合体を生成するためのマイクロウェル設計および製造 |
| US20170342363A1 (en) * | 2014-10-29 | 2017-11-30 | Corning Incorporated | Devices and methods for generation and culture of 3d cell aggregates |
| KR102460969B1 (ko) | 2014-10-29 | 2022-10-31 | 코닝 인코포레이티드 | 세포 배양 인서트 |
| WO2017127123A1 (en) | 2016-01-21 | 2017-07-27 | Abt Holding Company | Stem cells for wound healing |
| EP3652292B1 (en) | 2017-07-14 | 2025-06-18 | Corning Incorporated | Cell culture vessel for 3d culture and methods of culturing 3d cells |
| JP7197557B2 (ja) | 2017-07-14 | 2022-12-27 | コーニング インコーポレイテッド | 多孔性支持体を有する細胞培養槽 |
| CN111051494B (zh) | 2017-07-14 | 2024-03-29 | 康宁股份有限公司 | 用于手动或自动培养基交换的3d细胞培养容器 |
| US11857970B2 (en) | 2017-07-14 | 2024-01-02 | Corning Incorporated | Cell culture vessel |
| US11912968B2 (en) | 2018-07-13 | 2024-02-27 | Corning Incorporated | Microcavity dishes with sidewall including liquid medium delivery surface |
| JP7171696B2 (ja) | 2018-07-13 | 2022-11-15 | コーニング インコーポレイテッド | 相互接続されたウェルを有するマイクロプレートを備えた流体デバイス |
| EP3649229B1 (en) | 2018-07-13 | 2021-08-25 | Corning Incorporated | Cell culture vessels with stabilizer devices |
| CA3114565A1 (en) * | 2018-09-28 | 2020-04-02 | Nissan Chemical Corporation | Additive for medium for promoting production of paracrine factor |
| CA3160433A1 (en) * | 2019-12-09 | 2021-06-17 | Daewoong Pharmaceutical Co., Ltd. | Method for preparation of mesenchymal stem cell from human pluripotent stem cell and mesenchymal stem cells prepared thereby |
| CN113106059B (zh) * | 2021-04-07 | 2023-08-15 | 清华大学深圳国际研究生院 | 一种高迁徙间充质干细胞及其制备方法和应用 |
| CN115590883B (zh) * | 2021-07-07 | 2026-07-17 | 澳门大学 | 球体物质在制备静脉注射剂中的应用 |
| CN115354029B (zh) * | 2022-08-16 | 2023-09-01 | 上海长征医院 | 神经类器官的制备方法和神经类器官 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5446700A (en) * | 1999-05-28 | 2000-12-18 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | A combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector |
| GB0605450D0 (en) * | 2006-03-17 | 2006-04-26 | Intercytex Ltd | Cell co-culture |
| JP4991204B2 (ja) * | 2006-07-31 | 2012-08-01 | 株式会社オーガンテクノロジーズ | 歯の製造方法 |
| WO2008076556A2 (en) * | 2006-11-15 | 2008-06-26 | Massachusetts Eye & Ear Infirmary | Generation of inner ear cells |
| US20110165128A1 (en) * | 2008-03-07 | 2011-07-07 | Columbia University In The City Of New York | Homing in mesenchymal stem cells |
-
2010
- 2010-11-12 JP JP2012539009A patent/JP2013510582A/ja active Pending
- 2010-11-12 US US13/505,379 patent/US20120219572A1/en not_active Abandoned
- 2010-11-12 WO PCT/US2010/056502 patent/WO2011060244A1/en not_active Ceased
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