JP2013509433A - ウイルス関連疾患を処置する方法 - Google Patents

ウイルス関連疾患を処置する方法 Download PDF

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JP2013509433A
JP2013509433A JP2012537128A JP2012537128A JP2013509433A JP 2013509433 A JP2013509433 A JP 2013509433A JP 2012537128 A JP2012537128 A JP 2012537128A JP 2012537128 A JP2012537128 A JP 2012537128A JP 2013509433 A JP2013509433 A JP 2013509433A
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cmx001
virus
cells
jcv
compound
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JP2013509433A5 (enExample
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ペインター，ジョージ・アール
ラニア，アーネスト・ランドール
ペインター，ウェンディ
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キメリクス，インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2012537128A 2009-10-30 2010-10-29 ウイルス関連疾患を処置する方法 Pending JP2013509433A (ja)

Applications Claiming Priority (31)

Application Number Priority Date Filing Date Title
US25670109P 2009-10-30 2009-10-30
US61/256,701 2009-10-30
US32699110P 2010-04-22 2010-04-22
US32698610P 2010-04-22 2010-04-22
US32698210P 2010-04-22 2010-04-22
US32698910P 2010-04-22 2010-04-22
US61/326,986 2010-04-22
US61/326,982 2010-04-22
US61/326,991 2010-04-22
US61/326,989 2010-04-22
US32747410P 2010-04-23 2010-04-23
US61/327,474 2010-04-23
US32791410P 2010-04-26 2010-04-26
US61/327,914 2010-04-26
US32849110P 2010-04-27 2010-04-27
US61/328,491 2010-04-27
US33062410P 2010-05-03 2010-05-03
US61/330,624 2010-05-03
US33170410P 2010-05-05 2010-05-05
US61/331,704 2010-05-05
US35543010P 2010-06-16 2010-06-16
US61/355,430 2010-06-16
US40507510P 2010-10-20 2010-10-20
US40508010P 2010-10-20 2010-10-20
US40507310P 2010-10-20 2010-10-20
US40508410P 2010-10-20 2010-10-20
US61/405,080 2010-10-20
US61/405,075 2010-10-20
US61/405,084 2010-10-20
US61/405,073 2010-10-20
PCT/US2010/054779 WO2011053812A1 (en) 2009-10-30 2010-10-29 Methods of treating viral associated diseases

Publications (2)

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JP2013509433A true JP2013509433A (ja) 2013-03-14
JP2013509433A5 JP2013509433A5 (enExample) 2013-12-19

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US (2) US20130072458A1 (enExample)
EP (1) EP2493479A4 (enExample)
JP (1) JP2013509433A (enExample)
AU (1) AU2010313273B2 (enExample)
CA (1) CA2779473C (enExample)
WO (1) WO2011053812A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017530118A (ja) * 2014-09-15 2017-10-12 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ヌクレオチド類似体
WO2020138067A1 (ja) * 2018-12-25 2020-07-02 富士フイルム富山化学株式会社 ピラジン誘導体と細胞内におけるピラジン誘導体リボース三リン酸体の量を増加させる化合物とを組み合わせてなるｒｎａウイルス感染症治療剤
JP2022540273A (ja) * 2019-03-29 2022-09-15 エボニック オペレーションズ ゲーエムベーハー アントシアニン組成物と抗ウイルス剤とを含む組み合わせ製剤

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US8642577B2 (en) 2005-04-08 2014-02-04 Chimerix, Inc. Compounds, compositions and methods for the treatment of poxvirus infections
CN102670628B (zh) 2008-01-25 2015-11-25 奇默里克斯公司 治疗病毒感染的方法
WO2011011519A1 (en) 2009-07-21 2011-01-27 Chimerix, Inc. Compounds, compositions and methods for treating ocular conditions
HUE032860T2 (en) * 2010-02-12 2017-11-28 Chimerix Inc A method for treating a virus infection
US9278135B2 (en) 2010-04-26 2016-03-08 Chimerix Inc. Methods of treating retroviral infections and related dosage regimes
ES2604137T3 (es) 2010-08-31 2017-03-03 Chimerix, Inc. Derivados de éster de fosfonato y métodos de síntesis de los mismos
CA2853720A1 (en) * 2011-10-26 2013-05-02 Chimerix, Inc. Hexadecyloxypropyl cidofovir for the treatment of double-stranded dna virus infection
CA2857490C (en) 2011-12-22 2020-03-31 Geron Corporation Guanine analogs as telomerase substrates and telomere length affectors
EP2841162A4 (en) * 2012-04-27 2016-02-24 Chimerix Inc METHOD FOR CONTROLLING VIRUS ASSOCIATED ENDORGANIC DAMAGE
CN107312039B (zh) 2012-08-30 2019-06-25 江苏豪森药业集团有限公司 一种替诺福韦前药的制备方法
US9526729B2 (en) * 2013-01-29 2016-12-27 Hsiao Lily Yu Medicament for treating peripheral neuropathies
EP3401320B1 (en) 2013-03-15 2020-05-13 The Regents of the University of California Acyclic nucleoside phosphonate diesters for use in treating human papilloma virus, cervical intraepithelial neoplasia, anal intraepithelial neoplasia, or vulvar intraepithelial neoplasia
BR112016010862B1 (pt) 2013-11-15 2022-11-29 Chimerix, Inc Formas mórficas de ésteres de hexadeciloxipropilfosfonato, seu método de preparo e composição compreendendo a dita forma mórfica
WO2016069630A1 (en) 2014-10-27 2016-05-06 Concert Pharmaceuticals, Inc. Pyrimidine phosphonic acid esters bearing at least one deuterium atom
WO2017048956A1 (en) 2015-09-15 2017-03-23 The Regents Of The University Of California Nucleotide analogs
WO2017196990A1 (en) * 2016-05-12 2017-11-16 Contravir Pharmaceuticals, Inc. Methods of treating hepatitis b infections and related dosage regimes
EP3474822B1 (en) 2016-06-28 2025-07-09 Emergent BioDefense Operations Lansing LLC Formulations of brincidofovir
WO2018156879A1 (en) * 2017-02-23 2018-08-30 Chimerix, Inc. Treatment of adenovirus with brincidofovir
CN117285565A (zh) * 2022-06-24 2023-12-26 润佳（苏州）医药科技有限公司 核苷类似物及其医药用途
CA3262284A1 (en) 2022-07-21 2024-01-25 Antiva Biosciences, Inc. Pharmaceutical compositions and forms for the treatment of human papillomavirus (HPV) infection and HPV-induced neoplasm

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JP2008535862A (ja) * 2005-04-08 2008-09-04 キメリクス，インコーポレイテッド ポックスウイルス感染の治療のための化合物、組成物および方法
WO2008133966A1 (en) * 2007-04-27 2008-11-06 Chimerix, Inc. Methods of reducing nephrotoxicity in subjects administered with nucleoside

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017530118A (ja) * 2014-09-15 2017-10-12 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ヌクレオチド類似体
WO2020138067A1 (ja) * 2018-12-25 2020-07-02 富士フイルム富山化学株式会社 ピラジン誘導体と細胞内におけるピラジン誘導体リボース三リン酸体の量を増加させる化合物とを組み合わせてなるｒｎａウイルス感染症治療剤
JPWO2020138067A1 (ja) * 2018-12-25 2021-11-04 富士フイルム富山化学株式会社 ピラジン誘導体と細胞内におけるピラジン誘導体リボース三リン酸体の量を増加させる化合物とを組み合わせてなるｒｎａウイルス感染症治療剤
JP7369143B2 (ja) 2018-12-25 2023-10-25 富士フイルム富山化学株式会社 ピラジン誘導体と細胞内におけるピラジン誘導体リボース三リン酸体の量を増加させる化合物とを組み合わせてなるｒｎａウイルス感染症治療剤
JP2022540273A (ja) * 2019-03-29 2022-09-15 エボニック オペレーションズ ゲーエムベーハー アントシアニン組成物と抗ウイルス剤とを含む組み合わせ製剤
JP7523460B2 (ja) 2019-03-29 2024-07-26 エボニック オペレーションズ ゲーエムベーハー アントシアニン組成物と抗ウイルス剤とを含む組み合わせ製剤

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US20150141375A1 (en) 2015-05-21
CA2779473A1 (en) 2011-05-05
WO2011053812A1 (en) 2011-05-05
EP2493479A1 (en) 2012-09-05
AU2010313273B2 (en) 2015-04-02
US20130072458A1 (en) 2013-03-21
AU2010313273A1 (en) 2012-05-24
CA2779473C (en) 2016-08-16
EP2493479A4 (en) 2013-04-17

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