JP2013505939A5 - - Google Patents
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- Publication number
- JP2013505939A5 JP2013505939A5 JP2012531018A JP2012531018A JP2013505939A5 JP 2013505939 A5 JP2013505939 A5 JP 2013505939A5 JP 2012531018 A JP2012531018 A JP 2012531018A JP 2012531018 A JP2012531018 A JP 2012531018A JP 2013505939 A5 JP2013505939 A5 JP 2013505939A5
- Authority
- JP
- Japan
- Prior art keywords
- chloro
- methyl
- administered
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- LIRYPHYGHXZJBZ-UHFFFAOYSA-N CC(Nc1cc(N(C(C(C(N2C3CC3)=O)=C(Nc(ccc(I)c3)c3F)N3C)=C(C)C3=O)C2=O)ccc1)=O Chemical compound CC(Nc1cc(N(C(C(C(N2C3CC3)=O)=C(Nc(ccc(I)c3)c3F)N3C)=C(C)C3=O)C2=O)ccc1)=O LIRYPHYGHXZJBZ-UHFFFAOYSA-N 0.000 description 1
- WPJLXEJHHIOEGW-YOBAOWEQSA-N CN/C(/c(cc(C(N[C@@H](Cc(cc1F)ccc1F)CN)=O)[o]1)c1Cl)=C(\C=N)/Cl Chemical compound CN/C(/c(cc(C(N[C@@H](Cc(cc1F)ccc1F)CN)=O)[o]1)c1Cl)=C(\C=N)/Cl WPJLXEJHHIOEGW-YOBAOWEQSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24501909P | 2009-09-23 | 2009-09-23 | |
| US61/245,019 | 2009-09-23 | ||
| PCT/US2010/049946 WO2011038082A1 (en) | 2009-09-23 | 2010-09-23 | Combination |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015246931A Division JP2016106092A (ja) | 2009-09-23 | 2015-12-18 | 組合せ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013505939A JP2013505939A (ja) | 2013-02-21 |
| JP2013505939A5 true JP2013505939A5 (https=) | 2013-11-14 |
Family
ID=43796197
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012531018A Ceased JP2013505939A (ja) | 2009-09-23 | 2010-09-23 | 組合せ |
| JP2015246931A Pending JP2016106092A (ja) | 2009-09-23 | 2015-12-18 | 組合せ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015246931A Pending JP2016106092A (ja) | 2009-09-23 | 2015-12-18 | 組合せ |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20120322817A1 (https=) |
| EP (1) | EP2480084B1 (https=) |
| JP (2) | JP2013505939A (https=) |
| KR (1) | KR20120099219A (https=) |
| CN (1) | CN102770026B (https=) |
| AU (1) | AU2010298277B2 (https=) |
| BR (1) | BR112012006693A2 (https=) |
| CA (1) | CA2775124A1 (https=) |
| EA (1) | EA021951B1 (https=) |
| ES (1) | ES2527625T3 (https=) |
| IL (1) | IL218797A (https=) |
| MX (1) | MX2012003546A (https=) |
| WO (1) | WO2011038082A1 (https=) |
| ZA (1) | ZA201202173B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012061683A2 (en) * | 2010-11-05 | 2012-05-10 | Glaxosmithkline Llc | Methods for treating cancer |
| TWI505828B (zh) | 2010-12-20 | 2015-11-01 | 葛蘭素史克智慧財產（第二）有限公司 | 新穎醫藥組成物 |
| RU2013148817A (ru) * | 2011-04-01 | 2015-05-10 | Дженентек, Инк. | Комбинации соединений-ингибиторов акт и мек и способы их применения |
| EP2913048A1 (en) | 2014-02-27 | 2015-09-02 | ratiopharm GmbH | Pharmaceutical composition comprising trametinib |
| KR20200036022A (ko) * | 2017-08-11 | 2020-04-06 | 큐어매치, 아이엔씨. | 암에서 다중 돌연변이를 표적화하기 위한 약물 조합(drug combinations for targeting multiple mutations in cancer) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3811775B2 (ja) * | 2000-07-19 | 2006-08-23 | ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー | ４−ヨードフェニルアミノベンズヒドロキサム酸の酸素化エステル |
| US7378423B2 (en) * | 2004-06-11 | 2008-05-27 | Japan Tobacco Inc. | Pyrimidine compound and medical use thereof |
| SI1761528T1 (sl) * | 2004-06-11 | 2008-06-30 | Japan Tobacco Inc | 5-amino-2,4,7-triokso-3,4,7,8-tetrahidro-2H-pirido(2,3-D)pirimidinski derivati in sorodne spojine za zdravljenje raka |
| JP3821154B1 (ja) * | 2005-03-16 | 2006-09-13 | いすゞ自動車株式会社 | 排気ガス浄化方法及び排気ガス浄化システム |
| UY30892A1 (es) * | 2007-02-07 | 2008-09-02 | Smithkline Beckman Corp | Inhibidores de la actividad akt |
-
2010
- 2010-09-23 KR KR1020127010303A patent/KR20120099219A/ko not_active Ceased
- 2010-09-23 WO PCT/US2010/049946 patent/WO2011038082A1/en not_active Ceased
- 2010-09-23 BR BR112012006693A patent/BR112012006693A2/pt not_active IP Right Cessation
- 2010-09-23 EP EP10819435.8A patent/EP2480084B1/en active Active
- 2010-09-23 ES ES10819435.8T patent/ES2527625T3/es active Active
- 2010-09-23 CN CN201080052971.0A patent/CN102770026B/zh not_active Expired - Fee Related
- 2010-09-23 AU AU2010298277A patent/AU2010298277B2/en not_active Ceased
- 2010-09-23 JP JP2012531018A patent/JP2013505939A/ja not_active Ceased
- 2010-09-23 MX MX2012003546A patent/MX2012003546A/es active IP Right Grant
- 2010-09-23 CA CA2775124A patent/CA2775124A1/en not_active Abandoned
- 2010-09-23 EA EA201270445A patent/EA021951B1/ru not_active IP Right Cessation
- 2010-09-23 US US13/497,576 patent/US20120322817A1/en not_active Abandoned
-
2012
- 2012-03-22 IL IL218797A patent/IL218797A/en not_active IP Right Cessation
- 2012-03-23 ZA ZA2012/02173A patent/ZA201202173B/en unknown
-
2014
- 2014-05-06 US US14/270,774 patent/US20150094321A1/en not_active Abandoned
-
2015
- 2015-12-18 JP JP2015246931A patent/JP2016106092A/ja active Pending
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