JP2013504331A5 - - Google Patents

Download PDF

Info

Publication number
JP2013504331A5
JP2013504331A5 JP2012528991A JP2012528991A JP2013504331A5 JP 2013504331 A5 JP2013504331 A5 JP 2013504331A5 JP 2012528991 A JP2012528991 A JP 2012528991A JP 2012528991 A JP2012528991 A JP 2012528991A JP 2013504331 A5 JP2013504331 A5 JP 2013504331A5
Authority
JP
Japan
Prior art keywords
mir
protein
biomarker
tau
gfap
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012528991A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013504331A (ja
JP5909447B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/048789 external-priority patent/WO2011032155A2/en
Publication of JP2013504331A publication Critical patent/JP2013504331A/ja
Publication of JP2013504331A5 publication Critical patent/JP2013504331A5/ja
Application granted granted Critical
Publication of JP5909447B2 publication Critical patent/JP5909447B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012528991A 2009-09-14 2010-09-14 ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー Active JP5909447B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US24212309P 2009-09-14 2009-09-14
US61/242,123 2009-09-14
US35450410P 2010-06-14 2010-06-14
US61/354,504 2010-06-14
US35577910P 2010-06-17 2010-06-17
US61/355,779 2010-06-17
US38015810P 2010-09-03 2010-09-03
US61/380,158 2010-09-03
PCT/US2010/048789 WO2011032155A2 (en) 2009-09-14 2010-09-14 Micro-rna, autoantibody and protein markers for diagnosis of neuronal injury

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015253708A Division JP2016105097A (ja) 2009-09-14 2015-12-25 ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー

Publications (3)

Publication Number Publication Date
JP2013504331A JP2013504331A (ja) 2013-02-07
JP2013504331A5 true JP2013504331A5 (https=) 2013-12-19
JP5909447B2 JP5909447B2 (ja) 2016-04-26

Family

ID=43733138

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2012528991A Active JP5909447B2 (ja) 2009-09-14 2010-09-14 ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー
JP2015253708A Pending JP2016105097A (ja) 2009-09-14 2015-12-25 ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー
JP2017111070A Active JP6469760B2 (ja) 2009-09-14 2017-06-05 ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015253708A Pending JP2016105097A (ja) 2009-09-14 2015-12-25 ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー
JP2017111070A Active JP6469760B2 (ja) 2009-09-14 2017-06-05 ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー

Country Status (8)

Country Link
US (3) US20130022982A1 (https=)
EP (1) EP2478360B1 (https=)
JP (3) JP5909447B2 (https=)
AU (2) AU2010291933B2 (https=)
CA (1) CA2774173A1 (https=)
ES (1) ES2687469T3 (https=)
HU (1) HUE040281T2 (https=)
WO (1) WO2011032155A2 (https=)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8492107B2 (en) 2004-04-15 2013-07-23 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders
US12601749B2 (en) 2008-08-11 2026-04-14 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
JP5781436B2 (ja) 2008-08-11 2015-09-24 バンヤン・バイオマーカーズ・インコーポレーテッド 神経学的状態のバイオマーカー検出方法およびアッセイ
AU2010262952B2 (en) * 2009-06-19 2016-01-07 Banyan Biomarkers, Inc. Biomarker assay of neurological condition
US20170315136A9 (en) * 2009-06-19 2017-11-02 Banyan Biomarkers, Inc. Biomarker assay of neurological condition
AU2010291933B2 (en) 2009-09-14 2016-09-08 Banyan Biomarkers, Inc. Micro-RNA, autoantibody and protein markers for diagnosis of neuronal injury
WO2012045324A1 (en) * 2010-10-07 2012-04-12 Mediagnost Gesellschaft Fur Forschung Und Herstellung Von Diagnostika Gmbh Method for detecting a parkinson's disease and test system
WO2012051519A2 (en) 2010-10-14 2012-04-19 The Johns Hopkins University Biomarkers of brain injury
DE102011011280A1 (de) * 2011-02-15 2012-08-16 Euroimmun Medizinische Labordiagnostika Ag Diagnosekit sowie ein Verfahren zur Untersuchung einer menschlichen Patientenprobe auf das Vorhandensein von Neuromyelitis-optica-spezifischen Antikörpern
WO2012142301A2 (en) 2011-04-12 2012-10-18 Quanterix Corporation Methods of determining a treatment protocol for and/or a prognosis of a patients recovery from a brain injury
GB201111361D0 (en) * 2011-07-04 2011-08-17 Nordic Bioscience As Biochemical markers for neurodegenerative conditions
WO2013024469A1 (en) * 2011-08-16 2013-02-21 Rosetta Genomics Ltd. Methods and compositions for diagnosis of alzheimer's desease
HK1206425A1 (en) 2012-03-13 2016-01-08 The Johns Hopkins University Citrullinated brain and neurological proteins as biomarkers of brain injury or neurodegeneration
US20150119273A1 (en) * 2012-05-16 2015-04-30 Trustees Of Boston University Chronic Traumatic Encephalopathy in Blast-Exposed Individuals
SG10201708959WA (en) * 2012-07-03 2017-11-29 Univ Washington Antibodies to tau
US9856532B2 (en) * 2012-09-07 2018-01-02 Institute For Systems Biology Markers and methods for detecting posttraumatic stress disorder (PTSD)
US20140073524A1 (en) * 2012-09-07 2014-03-13 Institute For Systems Biology Markers and methods for detecting posttraumatic stress disorder (ptsd)
US10534003B2 (en) 2013-07-17 2020-01-14 The Johns Hopkins University Multi-protein biomarker assay for brain injury detection and outcome
GB201319761D0 (en) * 2013-11-08 2013-12-25 Nordic Bioscience As Biomarkers of disease progression
CN103656685B (zh) * 2014-01-10 2016-01-13 厦门大学 microRNA-219在制备抗癫痫药物中的应用
WO2015134551A1 (en) * 2014-03-03 2015-09-11 Banyan Biomarkers, Inc. Micro rna markers for diagnosis of a neurological condition
US9605315B2 (en) 2014-03-26 2017-03-28 The University Of Montana Detection of traumatic brain injury
EP3129780A4 (en) * 2014-04-07 2017-12-13 Iron Horse Diagnostics Inc. Traumatic brain injury and neurodegenerative biomarkers, methods, and systems
CN106605146B (zh) * 2014-04-08 2020-07-28 佛罗里达大学研究基金会有限公司 用于中枢神经系统的急性、亚急性和慢性创伤性损伤的蛋白质标志物
WO2015160391A1 (en) * 2014-04-15 2015-10-22 The Government Of The United States, As Represented By The Secretary Of The Army, On Behalf Of Walter Reed Army Institute Of Research Diagnosis and treatment of tauopathy and chronic traumatic encephalopathy
WO2015196191A1 (en) * 2014-06-20 2015-12-23 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Microrna biomarkers for traumatic brain injury and methods of use thereof
CA2962593A1 (en) * 2014-09-26 2016-03-31 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Microrna biomarkers for posttraumatic stress disorder and methods of use thereof
WO2016055148A2 (en) * 2014-10-06 2016-04-14 Université De Genève Markers and their use in brain injury
US20180024145A1 (en) 2015-02-05 2018-01-25 Immunarray USA, Inc. Methods and compositions for diagnosing brain injury or neurodegeneration
WO2016205730A1 (en) * 2015-06-18 2016-12-22 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Citrullinated proteins and their breakdown products as tbi biomarkers
JP2018522558A (ja) * 2015-07-29 2018-08-16 ザ ヘンリー エム. ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド 外傷性脳損傷のためのマイクロrnaバイオマーカー、及びその使用方法
US11053545B2 (en) 2015-09-08 2021-07-06 The Translational Genomics Research Institute Biomarkers and methods of diagnosing and prognosing mild traumatic brain injuries
WO2017087726A1 (en) * 2015-11-18 2017-05-26 Dignity Health Methods of diagnosing epilepsy
GB201603967D0 (en) * 2016-03-08 2016-04-20 Univ Birmingham Biomarkers of traumatic brain injury
JP6430680B2 (ja) * 2016-04-28 2018-11-28 一般財団法人生産技術研究奨励会 神経細胞を培養する装置、神経細胞を培養する方法、培養された神経細胞、軸索束内のプロテインを解析及び同定する方法並びに神経細胞の使用方法
WO2017193119A1 (en) * 2016-05-06 2017-11-09 Duke University Methods and kits for diagnosing and treating nervous system disease or injury
US11402379B2 (en) 2016-09-09 2022-08-02 Mayo Foundation For Medical Education And Research Methods and materials for identifying and treating autoimmune GFAP astrocytopathy
IT201600093825A1 (it) * 2016-09-19 2018-03-19 Fondazione St Italiano Tecnologia Composizione farmaceutica di miRNA e suoi usi terapeutici.
US11078298B2 (en) 2016-10-28 2021-08-03 Banyan Biomarkers, Inc. Antibodies to ubiquitin C-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) and related methods
WO2018096049A1 (en) * 2016-11-23 2018-05-31 Randox Laboratories Ltd Gfap derivatives for stroke diagnostics
WO2018148294A2 (en) * 2017-02-07 2018-08-16 Bioregency, Inc. S100β AND ISOFORMS FOR DETECTION OF NEUROLOGICAL CONDITIONS
SG11201907422RA (en) 2017-02-17 2019-09-27 Denali Therapeutics Inc Anti-tau antibodies and methods of use thereof
CA3261113A1 (en) 2017-03-23 2025-10-27 Abbott Laboratories Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1
WO2018190365A1 (ja) * 2017-04-12 2018-10-18 国立大学法人九州大学 神経障害性疼痛マーカー及びその使用
WO2018191531A1 (en) 2017-04-15 2018-10-18 Abbott Laboratories Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers
ES3053676T3 (en) 2017-04-28 2026-01-23 Abbott Lab Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject
US10866251B2 (en) 2017-05-25 2020-12-15 Abbott Laboratories Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
JP7269182B2 (ja) 2017-05-30 2023-05-08 アボット・ラボラトリーズ 心臓トロポニンi及び早期バイオマーカーを使用する、ヒト対象における軽度外傷性脳損傷を診断及び査定する一助となるための方法
CN110998321A (zh) * 2017-06-02 2020-04-10 约翰霍普金斯大学 帕金森氏症患者脑脊液中par的检测方法
US20210148898A1 (en) 2017-06-02 2021-05-20 The Johns Hopkins University Detection of par in the csf of patients with parkinson's disease
EP4410998B1 (en) * 2017-06-19 2026-03-11 St. John's University Circulating serum microrna biomarkers and methods for determining the progression rate of parkinson's disease
US11169159B2 (en) 2017-07-03 2021-11-09 Abbott Laboratories Methods for measuring ubiquitin carboxy-terminal hydrolase L1 levels in blood
CN111787942B (zh) 2017-10-25 2024-03-29 杨森制药公司 磷酸化Tau肽的组合物及其用途
JP6942036B2 (ja) * 2017-11-30 2021-09-29 藤倉化成株式会社 脳梗塞の発症リスクを高感度に検出する体液抗体バイオマーカー
JP7379165B2 (ja) 2017-12-09 2023-11-14 アボット・ラボラトリーズ Gfapとuch-l1との組合せを使用する、ヒト対象における外傷性脳損傷を診断及び査定する一助となるための方法
EP3721233A2 (en) 2017-12-09 2020-10-14 Abbott Laboratories Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
CN111699391A (zh) 2017-12-29 2020-09-22 雅培实验室 用于诊断和评估创伤性脑损伤的新型生物标志物和方法
KR102026675B1 (ko) * 2018-02-12 2019-09-30 강원대학교산학협력단 miR-135a-5p 및 p62에 의한 알레르기 반응 조절 메커니즘 및 이의 이용
US12339275B2 (en) 2018-03-08 2025-06-24 Meso Scale Technologies, Llc. Genetic marker and/or biomarkers for traumatic brain injury, and ultrasensitive assays for biomarkers of traumatic brain injury
JP6499342B2 (ja) * 2018-03-19 2019-04-10 隆樹 日和佐 脳梗塞の診断マーカー
US20210230255A1 (en) * 2018-04-27 2021-07-29 Fondazione Ebri Rita Levi-Montalcini Antibody directed against a tau-derived neurotoxic peptide and uses thereof
KR20210038585A (ko) * 2018-07-25 2021-04-07 에스알엔에이리틱스, 인크. 알츠하이머병에 대한 작은 rna 예측인자
CN110824156B (zh) * 2018-08-14 2023-08-11 欧蒙医学诊断(中国)有限公司 神经自身免疫疾病的诊断
US20210270847A1 (en) * 2018-08-17 2021-09-02 University Of Florida Research Foundation, Incorporated Protein and peptide biomarkers for traumatic injury to the central nervous system
CN113195740A (zh) * 2018-10-17 2021-07-30 奥克斯纳健康系统公司 在脑内出血和蛛网膜下腔出血中的血浆和脑脊液miRNA生物标志物
CN109266739A (zh) * 2018-11-29 2019-01-25 成都仕康美生物科技有限公司 一种检测脑损伤的miRNA标志物、试剂盒、应用
EP3891295B1 (en) * 2018-12-04 2026-03-25 La Trobe University Methods of diagnosing a disease state
MY206596A (en) 2019-02-08 2024-12-25 Janssen Pharmaceuticals Inc Method of safe administration of phosphorylated tau peptide vaccine
JP7738481B2 (ja) * 2019-02-14 2025-09-12 マーカー ダイアグノスティクス ユーケイ リミテッド 脳損傷の唾液バイオマーカー
GB201909393D0 (en) 2019-06-28 2019-08-14 Gen2 Neuroscience Ltd Tau epitope and binding molecules
CN110551809A (zh) * 2019-08-21 2019-12-10 昆明医科大学第一附属医院 miR-124在脊髓损伤修复中的用途
US11644463B2 (en) * 2019-08-30 2023-05-09 Euroimmun Medizinische Labordiagnostika Ag Detection of an autoantibody
US20230250480A1 (en) * 2020-07-09 2023-08-10 University Of Florida Research Foundation, Incorporated Biofluid-based protein and mirna biomarkers for neonatal hypoxic-ischemic encephalopathy
CA3190526A1 (en) * 2020-08-24 2022-03-03 Marabio Systems, Inc. Methods for reducing maternal autoantibodies
KR102357260B1 (ko) * 2020-12-10 2022-02-08 주식회사 레피겐엠디 마이크로rna를 이용한 당뇨병성 신경병증의 예측 및 진단 방법 및 이를 위한 키트
CN113238045B (zh) * 2021-04-27 2021-12-28 南方医科大学南方医院 Crmp2及抗crmp2抗体的应用
KR102759445B1 (ko) * 2021-11-16 2025-01-24 한국한의학연구원 치료에 따른 보행 장애 개선 판별용 바이오마커 및 이의 용도
TWI853766B (zh) * 2022-12-22 2024-08-21 國立臺灣大學 用於心跳停止病患頭部電腦斷層之灰白質比率自動計算方法
WO2025235699A1 (en) * 2024-05-08 2025-11-13 Owi Therapeutics Llc Astrocytic monomeric, oligomeric, or aggregate breakdown products of glial fibrillary acidic protein

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567588A (en) 1990-06-11 1996-10-22 University Research Corporation Systematic evolution of ligands by exponential enrichment: Solution SELEX
US5660985A (en) 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
US6011020A (en) 1990-06-11 2000-01-04 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand complexes
ES2259800T3 (es) 1990-06-11 2006-10-16 Gilead Sciences, Inc. Procedimientos de uso de ligandos de acido nucleico.
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
US5683867A (en) 1990-06-11 1997-11-04 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: blended SELEX
US5637459A (en) 1990-06-11 1997-06-10 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chimeric selex
US5707796A (en) 1990-06-11 1998-01-13 Nexstar Pharmaceuticals, Inc. Method for selecting nucleic acids on the basis of structure
US5496938A (en) 1990-06-11 1996-03-05 Nexstar Pharmaceuticals, Inc. Nucleic acid ligands to HIV-RT and HIV-1 rev
EP0600951A4 (en) * 1991-08-01 1996-10-30 Paul H Voorheis Diagnostic method for alzheimer's disease.
US5731410A (en) 1994-11-28 1998-03-24 University Of Utah Research Foundation Peptide for blocking autoantibody-evoked activation of glutamate receptor type 3 (GLUR3)
BR9913112A (pt) * 1998-09-08 2001-05-08 Innogenetics Nv Tau como um marcador para dano inicial de cns
US20020002270A1 (en) 1999-06-16 2002-01-03 Raymond P. Zinkowski Purified antigen for alzheimer's disease, and methods of obtaining and using same
US6589746B1 (en) * 1999-10-21 2003-07-08 University Of Cincinnati Method of detecting axonally-derived protein tau in patients with traumatic CNS injury
US20040253637A1 (en) 2001-04-13 2004-12-16 Biosite Incorporated Markers for differential diagnosis and methods of use thereof
US7713705B2 (en) 2002-12-24 2010-05-11 Biosite, Inc. Markers for differential diagnosis and methods of use thereof
US20040203083A1 (en) 2001-04-13 2004-10-14 Biosite, Inc. Use of thrombus precursor protein and monocyte chemoattractant protein as diagnostic and prognostic indicators in vascular diseases
US20030199000A1 (en) 2001-08-20 2003-10-23 Valkirs Gunars E. Diagnostic markers of stroke and cerebral injury and methods of use thereof
US20020172676A1 (en) * 2001-05-16 2002-11-21 George Jackowski Method of treatment of alzheimer's disease and device therefor
US7144708B2 (en) 2001-06-25 2006-12-05 The Cleveland Clinic Foundation Markers of blood barrier disruption and methods of using same
DE60233949D1 (de) 2001-08-20 2009-11-19 Biosite Inc Diagnostische marker für schlaganfall und hirntrauma sowie verfahren zur verwendung davon
AU2002329570A1 (en) 2001-10-12 2003-01-30 Pfizer Products Inc. Method of monitoring neuroprotective treatment
AU2003243563A1 (en) 2002-06-12 2004-09-28 The Cleveland Clinic Foundation Markers of blood barrier permeability and methods of using same
EP2211176A3 (en) 2002-09-11 2010-12-08 University Of Florida Analyzing nerve cell damage
JP2006526140A (ja) 2002-12-24 2006-11-16 バイオサイト インコーポレイテッド 鑑別診断のためのマーカーおよびその使用方法
DK2341350T3 (en) 2003-09-20 2018-02-05 Electrophoretics Ltd DIAGNOSTIC PROCEDURE FOR BRAKE INJURY-RELATED DISORDERS BASED ON DJ-1 DETECTION
EP1519194A1 (en) 2003-09-24 2005-03-30 Roche Diagnostics GmbH Use of gfap for identification of intracerebral hemorrhage
US7396654B2 (en) 2004-04-15 2008-07-08 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for traumatic brain injury
US8492107B2 (en) 2004-04-15 2013-07-23 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders
US20140303041A1 (en) 2004-04-15 2014-10-09 University Of Florida Research Foundation Inc. In vitro diagnostic devices for nervous system injury and other neural disorders
ES2367311T3 (es) 2004-04-15 2011-11-02 University Of Florida Research Foundation, Inc. Productos de degradación proteolítica de map-2 como biomarcadores de diagnóstico para las lesiones neurales.
GB2428240A (en) 2005-07-14 2007-01-24 Univ Gen Ve Diagnostic method for brain damage-related disorders
EP1949103A2 (en) 2005-10-20 2008-07-30 Biosite Incorporated Diagnostic markers of stroke and cerebral injury and methods of use thereof
EP1992688B1 (en) 2006-02-15 2016-06-22 Mie University Method of constructing recombinant proteoliposome for diagnostic use
WO2007136617A2 (en) * 2006-05-18 2007-11-29 Walter Reed Army Institute Of Research (Wrair) Endothelial-monocyte activating polypeptide ii, a biomarker for use in diagnosis of brain injury
WO2007140188A2 (en) 2006-05-26 2007-12-06 Biosite Incorporated Use of natriuretic peptides as diagnostic and prognostic indicators in vascular diseases
WO2009100131A2 (en) * 2008-02-04 2009-08-13 Banyan Biomarkers, Inc. Process to diagnose or treat brain injury
EP2143735A1 (en) 2008-07-10 2010-01-13 Institut Pasteur Variable domains of camelid heavy-chain antibodies directed against glial fibrillary acidic proteins
JP5781436B2 (ja) 2008-08-11 2015-09-24 バンヤン・バイオマーカーズ・インコーポレーテッド 神経学的状態のバイオマーカー検出方法およびアッセイ
US20140342381A1 (en) 2008-08-11 2014-11-20 Banyan Biomarkers, Inc. Devices and methods for biomarker detection process and assay of neurological condition
US20120094295A1 (en) 2008-11-21 2012-04-19 The Johns Hopkins University Neurodegenerative disease diagnostic compositions and methods of use
AU2010262952B2 (en) * 2009-06-19 2016-01-07 Banyan Biomarkers, Inc. Biomarker assay of neurological condition
US20170315136A9 (en) 2009-06-19 2017-11-02 Banyan Biomarkers, Inc. Biomarker assay of neurological condition
WO2011011334A2 (en) 2009-07-18 2011-01-27 Banyan Biomarkers, Inc. SYNERGISTIC BIOMARKER ASSAY OF NEUROLGICAL CONDITION USING S-100β
AU2010291933B2 (en) 2009-09-14 2016-09-08 Banyan Biomarkers, Inc. Micro-RNA, autoantibody and protein markers for diagnosis of neuronal injury
EP2553466A4 (en) 2010-04-01 2013-10-16 Banyan Biomarkers Inc MARKERS AND ASSAYS FOR DETECTING NEUROTOXICITY
WO2011160096A2 (en) 2010-06-17 2011-12-22 Banyan Biomarkers, Inc. Glial fibrillary acidic protein, autoantigens and autoantibodies thereto as biomarkers of neural injury or neurological disorder or condition
US20150259740A1 (en) 2011-09-14 2015-09-17 Harvey Pollard Processes and kits to detect and monitor for diagnostic biomarkers for post traumatic stress disorder (ptsd) and to differentiate between suicidal and non-suicidal form of the disorder
US20140024053A1 (en) 2012-07-20 2014-01-23 Banyan Biomarkers, Inc. Methods, kits and devices for detecting bii-spectrin, and breakdown products thereof, as biomarkers for the diagnosis of neural injury
US20140275294A1 (en) 2013-03-15 2014-09-18 Banyan Biomarkers, Inc. Devices and methods for biomarker detection process and assay of liver injury
WO2014194329A1 (en) 2013-05-31 2014-12-04 Banyan Biomarkers, Inc. NEURAL SPECIFIC S100β FOR BIOMARKER ASSAYS AND DEVICES FOR DETECTION OF A NEUROLOGICAL CONDITION

Similar Documents

Publication Publication Date Title
JP2013504331A5 (https=)
Roy et al. Role of miRNAs in neurodegeneration: From disease cause to tools of biomarker discovery and therapeutics
Ho et al. MicroRNA-based diagnosis and therapy
Leggio et al. microRNAs in Parkinson’s disease: from pathogenesis to novel diagnostic and therapeutic approaches
Zhang et al. The role of non-coding RNAs in Alzheimer’s disease: from regulated mechanism to therapeutic targets and diagnostic biomarkers
Singh et al. MicroRNAs in Parkinson’s disease
Wang et al. The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of β-site amyloid precursor protein-cleaving enzyme 1
Olufunmilayo et al. Roles of non-coding RNA in Alzheimer’s disease pathophysiology
Dehghani et al. MicroRNA in Alzheimer’s disease revisited: implications for major neuropathological mechanisms
US20230044119A1 (en) Therapeutic Editing
Scopa et al. JUN upregulation drives aberrant transposable element mobilization, associated innate immune response, and impaired neurogenesis in Alzheimer’s disease
Shi Regulatory networks between neurotrophins and miRNAs in brain diseases and cancers
Kinoshita et al. Interplay of RNA-binding proteins and microRNAs in neurodegenerative diseases
He et al. Diagnostic and therapeutic potential of exosomal microRNAs for neurodegenerative diseases
Mohammadi et al. MicroRNAs and synaptic plasticity: from their molecular roles to response to therapy
Niazi et al. MicroRNA Nobel Prize: Timely recognition and high anticipation of future products—A prospective analysis
Klokkaris et al. An overview of epigenetic changes in the Parkinson’s disease brain
Puranik et al. Insights into the role of microRNAs as clinical tools for diagnosis, prognosis, and as therapeutic targets in Alzheimer’s disease
Patranabis Recent advances in the miRNA-mediated regulation of neuronal differentiation and death
Zhang et al. Recent advances in the roles of microRNA and microRNA-based diagnosis in neurodegenerative diseases
Shademan et al. MicroRNAs as a new target for Alzheimer's disease treatment
Kaur et al. Understanding the multifaceted role of miRNAs in Alzheimer’s disease pathology
Huang et al. MicroRNA and Alzheimer’s disease: Diagnostic biomarkers and potential therapeutic targets
WO2022204362A2 (en) Compositions and methods for treating a neurodegenerative or developmental disorder
Lui et al. Tumor suppressor MicroRNAs in clinical and preclinical trials for neurological disorders