JP2013503915A5 - - Google Patents
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- Publication number
- JP2013503915A5 JP2013503915A5 JP2012528399A JP2012528399A JP2013503915A5 JP 2013503915 A5 JP2013503915 A5 JP 2013503915A5 JP 2012528399 A JP2012528399 A JP 2012528399A JP 2012528399 A JP2012528399 A JP 2012528399A JP 2013503915 A5 JP2013503915 A5 JP 2013503915A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24040209P | 2009-09-08 | 2009-09-08 | |
| US61/240,402 | 2009-09-08 | ||
| US32303210P | 2010-04-12 | 2010-04-12 | |
| US61/323,032 | 2010-04-12 | ||
| PCT/FI2010/050689 WO2011029996A1 (en) | 2009-09-08 | 2010-09-07 | Use of vap-1 inhibitors for treating fibrotic conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016003089A Division JP6290940B2 (ja) | 2009-09-08 | 2016-01-08 | 診断剤、完全ヒト抗ｖａｐ−１抗体の使用、及びキット |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013503915A JP2013503915A (ja) | 2013-02-04 |
| JP2013503915A5 true JP2013503915A5 (enExample) | 2016-03-31 |
| JP6009355B2 JP6009355B2 (ja) | 2016-10-19 |
Family
ID=43732037
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012528399A Expired - Fee Related JP6009355B2 (ja) | 2009-09-08 | 2010-09-07 | Ｖａｐ−１阻害剤、およびｖａｐ−１阻害剤の使用 |
| JP2016003089A Expired - Fee Related JP6290940B2 (ja) | 2009-09-08 | 2016-01-08 | 診断剤、完全ヒト抗ｖａｐ−１抗体の使用、及びキット |
| JP2018020789A Pending JP2018104445A (ja) | 2009-09-08 | 2018-02-08 | 線維性疾患治療のためのｖａｐ−１阻害剤の使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016003089A Expired - Fee Related JP6290940B2 (ja) | 2009-09-08 | 2016-01-08 | 診断剤、完全ヒト抗ｖａｐ−１抗体の使用、及びキット |
| JP2018020789A Pending JP2018104445A (ja) | 2009-09-08 | 2018-02-08 | 線維性疾患治療のためのｖａｐ−１阻害剤の使用 |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US9795671B2 (enExample) |
| EP (1) | EP2475387B1 (enExample) |
| JP (3) | JP6009355B2 (enExample) |
| KR (2) | KR20180026808A (enExample) |
| CN (2) | CN102740886A (enExample) |
| AU (1) | AU2010294123B2 (enExample) |
| CA (1) | CA2773218C (enExample) |
| CY (1) | CY1119867T1 (enExample) |
| DK (1) | DK2475387T3 (enExample) |
| ES (1) | ES2657943T3 (enExample) |
| HR (1) | HRP20180131T1 (enExample) |
| HU (1) | HUE035890T2 (enExample) |
| IL (1) | IL218535A (enExample) |
| LT (1) | LT2475387T (enExample) |
| ME (1) | ME02999B (enExample) |
| NO (1) | NO2475387T3 (enExample) |
| NZ (3) | NZ616432A (enExample) |
| PL (1) | PL2475387T3 (enExample) |
| PT (1) | PT2475387T (enExample) |
| RS (1) | RS56809B1 (enExample) |
| RU (2) | RU2580626C2 (enExample) |
| SG (1) | SG179012A1 (enExample) |
| SI (1) | SI2475387T1 (enExample) |
| SM (1) | SMT201800043T1 (enExample) |
| UA (1) | UA112154C2 (enExample) |
| WO (1) | WO2011029996A1 (enExample) |
| ZA (1) | ZA201202515B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA112154C2 (uk) | 2009-09-08 | 2016-08-10 | Біоті Терапіс Корп. | Застосування повністю людського анти-vap-1-антитіла для лікування фіброзних станів |
| JP5953035B2 (ja) * | 2011-11-28 | 2016-07-13 | 学校法人慶應義塾 | 病理診断支援装置、病理診断支援方法、及び病理診断支援プログラム |
| EP2844637B1 (en) | 2012-05-02 | 2018-03-28 | Boehringer Ingelheim International GmbH | Substituted 3-haloallylamine inhibitors of ssao and uses thereof |
| WO2014024820A1 (ja) * | 2012-08-06 | 2014-02-13 | 塩野義製薬株式会社 | 新規慢性腎臓病治療用医薬組成物及び新規慢性腎臓病治療薬のスクリーニング方法 |
| KR102205845B1 (ko) | 2013-10-28 | 2021-01-22 | 삼성전자주식회사 | 입자에 기반한 모델링 방법 및 장치 |
| WO2015189534A1 (en) * | 2014-06-12 | 2015-12-17 | Proximagen Limited | Vap-1 inhibitors for treating muscular dystrophy |
| JP2018080114A (ja) * | 2015-05-29 | 2018-05-24 | 株式会社アールテック・ウエノ | 抗ヒトｖａｐ−１モノクローナル抗体 |
| EP3645039A4 (en) * | 2017-06-27 | 2021-05-05 | Neuracle Science Co., Ltd | USE OF ANTI-FAM19A5 ANTIBODIES TO TREAT FIBROSIS |
| CN119156402A (zh) * | 2022-02-23 | 2024-12-17 | 耶鲁大学 | 用作肾病治疗物的il-6抑制剂 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4997854A (en) * | 1989-08-25 | 1991-03-05 | Trustees Of Boston University | Anti-fibrotic agents and methods for inhibiting the activity of lysyl oxidase in-situ using adjacently positioned diamine analogue substrates |
| US5580780A (en) | 1992-06-09 | 1996-12-03 | Jalkanen; Sirpa | Vascular adhesion protein-(VAP-1) and VAP-1-specific antibodies |
| HUP0002234A3 (en) * | 1997-05-23 | 2005-11-28 | Biotie Therapies Ltd | Vascular adhesion protein-1 having oxidase activity |
| PL360374A1 (en) * | 2000-07-05 | 2004-09-06 | Biotie Therapies Corporation | Inhibitors of copper-containing amine oxidases |
| WO2002038153A1 (en) * | 2000-11-09 | 2002-05-16 | Biovitrum Ab | New use of 4, 5, 6, 7-tetrahydroimidazo-[4,5-c]pyridine derivatives |
| EP1353676A4 (en) | 2000-12-29 | 2006-05-31 | Alteon Inc | METHOD FOR THE TREATMENT OF FIBROUS OR OTHER INDICATIONS |
| US6982286B2 (en) * | 2001-07-12 | 2006-01-03 | Biotie Therapies Corp. | Carbocyclic hydrazino inhibitors of copper-containing amine oxidases |
| FI20020807A0 (fi) * | 2002-04-29 | 2002-04-29 | Biotie Therapies Oyj | Uusia humanisoituja anti-VAP-1 monoklonaalisia vasta-aineita |
| AR042941A1 (es) | 2003-01-27 | 2005-07-06 | Fujisawa Pharmaceutical Co | Derivados de tiazol, su preparacion, composiciones farmaceuticas que los contienen y su uso en la fabricacion de medicamentos inhibidores de la proteina-1 de adhesion vascular (vap-1) |
| CN1794988B (zh) * | 2003-03-31 | 2010-07-28 | 株式会社·R-技术上野 | 用于治疗血管渗透性过高疾病的组合物 |
| US20050096360A1 (en) | 2003-08-08 | 2005-05-05 | Salter-Cid Luisa M. | Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment of diseases |
| JP2007519688A (ja) | 2004-01-30 | 2007-07-19 | ファロン ファーマシューティカルズ オサケ ユキチュア | メタボリックシンドロームの治療または予防に特に有効な組成物 |
| FI20040270A0 (fi) | 2004-02-20 | 2004-02-20 | Biotie Therapies Oyj | Kuparia sisältävien amiinioksidaasien imhibiittoreina käyttökelpoiset hydratsinoalkoholijohdannaiset |
| EP2283833A3 (en) | 2004-02-25 | 2013-07-10 | La Jolla Pharmaceutical Co. | Amines and amides for the treatment of diseases |
| CA2558135C (en) | 2004-03-18 | 2012-08-14 | R-Tech Ueno, Ltd. | Aqueous composition comprising thiazole derivative |
| DE602005013793D1 (de) | 2004-07-27 | 2009-05-20 | Astellas Pharma Inc | Thiazolderivate mit vap-1-hemmender wirkung |
| WO2006013209A2 (en) | 2004-08-02 | 2006-02-09 | Genmedica Therapeutics Sl | Compounds for inhibiting copper-containing amine oxidases and uses thereof |
| CA2579889A1 (en) | 2004-09-09 | 2006-03-16 | Astellas Pharma Inc. | Thiazole derivatives having vap-1 inhibitory activity |
| WO2006094201A2 (en) * | 2005-03-02 | 2006-09-08 | La Jolla Pharmaceutical Company | Semicarbazide-sensitive amide oxidase inhibitors |
| WO2007005737A2 (en) | 2005-07-01 | 2007-01-11 | Case Western Reserve University | Amine oxidase inhibitors |
| US20070066646A1 (en) | 2005-08-02 | 2007-03-22 | Genmedica Therapeutics Sl | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof |
| US20080058922A1 (en) * | 2006-08-31 | 2008-03-06 | Cardiac Pacemakers, Inc. | Methods and devices employing vap-1 inhibitors |
| FI20075278A0 (fi) * | 2007-04-20 | 2007-04-20 | Biotie Therapies Corp | Uudet täysin ihmisperäiset anti-VAP-1 monoklonaaliset vasta-aineet |
| WO2009055002A1 (en) | 2007-10-24 | 2009-04-30 | La Jolla Pharmaceutical Company | Combined inhibitors of cyclooxygenase and semicarbazide-sensitive amine oxidase (ssao) (vascular adhesion protein, vap-1) |
| NZ585528A (en) * | 2007-11-21 | 2012-08-31 | Pharmaxis Ltd | Haloallylamine inhibitors of ssao/vap-1 and uses therefor |
| TWI437986B (zh) * | 2008-01-31 | 2014-05-21 | R Tech Ueno Ltd | 噻唑衍生物及使用該衍生物作為ｖａｐ－１抑制劑之用途 |
| TWI490214B (zh) | 2008-05-30 | 2015-07-01 | 艾德克 上野股份有限公司 | 苯或噻吩衍生物及該等作為ｖａｐ－１抑制劑之用途 |
| HUP0800498A2 (en) | 2008-08-06 | 2010-03-29 | Semmelweis Egyetem | Use of dihydralazine for the preparation of medicaments for treatment of diseases related to ssao level |
| ES2545966T3 (es) | 2008-09-11 | 2015-09-17 | Semmelweis Egyetem | Compuestos para inhibir la amina oxidasa sensible a semicarbazida (SSAO) y la proteína 1 de adhesión vascular (VAP-1) y sus usos para el tratamiento y prevención de enfermedades |
| CA2737527C (en) * | 2008-09-16 | 2015-12-29 | Proximagen Limited | 4,5,6,7-tetrahydroimidazo[4,5-c]pyridine compounds useful as inhibitors of ssao activity |
| DK2376490T3 (da) | 2008-12-04 | 2013-04-15 | Proximagen Ltd | Imidazopyridinforbindelser |
| UA112154C2 (uk) * | 2009-09-08 | 2016-08-10 | Біоті Терапіс Корп. | Застосування повністю людського анти-vap-1-антитіла для лікування фіброзних станів |
-
2010
- 2010-07-09 UA UAA201204308A patent/UA112154C2/uk unknown
- 2010-09-07 RU RU2012113561/15A patent/RU2580626C2/ru active
- 2010-09-07 ES ES10815041.8T patent/ES2657943T3/es active Active
- 2010-09-07 HR HRP20180131TT patent/HRP20180131T1/hr unknown
- 2010-09-07 DK DK10815041.8T patent/DK2475387T3/en active
- 2010-09-07 NZ NZ61643210A patent/NZ616432A/en not_active IP Right Cessation
- 2010-09-07 EP EP10815041.8A patent/EP2475387B1/en active Active
- 2010-09-07 JP JP2012528399A patent/JP6009355B2/ja not_active Expired - Fee Related
- 2010-09-07 LT LTEP10815041.8T patent/LT2475387T/lt unknown
- 2010-09-07 RU RU2016107043A patent/RU2667963C1/ru active
- 2010-09-07 KR KR1020187006357A patent/KR20180026808A/ko not_active Ceased
- 2010-09-07 NO NO10815041A patent/NO2475387T3/no unknown
- 2010-09-07 CN CN2010800503481A patent/CN102740886A/zh active Pending
- 2010-09-07 SI SI201031624T patent/SI2475387T1/en unknown
- 2010-09-07 CA CA2773218A patent/CA2773218C/en not_active Expired - Fee Related
- 2010-09-07 NZ NZ598920A patent/NZ598920A/en not_active IP Right Cessation
- 2010-09-07 AU AU2010294123A patent/AU2010294123B2/en not_active Ceased
- 2010-09-07 RS RS20180101A patent/RS56809B1/sr unknown
- 2010-09-07 PL PL10815041T patent/PL2475387T3/pl unknown
- 2010-09-07 US US13/395,029 patent/US9795671B2/en not_active Expired - Fee Related
- 2010-09-07 SG SG2012015772A patent/SG179012A1/en unknown
- 2010-09-07 NZ NZ706740A patent/NZ706740A/en not_active IP Right Cessation
- 2010-09-07 WO PCT/FI2010/050689 patent/WO2011029996A1/en not_active Ceased
- 2010-09-07 PT PT108150418T patent/PT2475387T/pt unknown
- 2010-09-07 HU HUE10815041A patent/HUE035890T2/en unknown
- 2010-09-07 KR KR1020127009075A patent/KR101837117B1/ko not_active Expired - Fee Related
- 2010-09-07 SM SM20180043T patent/SMT201800043T1/it unknown
- 2010-09-07 CN CN201710879422.4A patent/CN107661500A/zh active Pending
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2012
- 2012-03-07 IL IL218535A patent/IL218535A/en active IP Right Grant
- 2012-04-05 ZA ZA2012/02515A patent/ZA201202515B/en unknown
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2016
- 2016-01-08 JP JP2016003089A patent/JP6290940B2/ja not_active Expired - Fee Related
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2017
- 2017-09-21 US US15/711,828 patent/US10576148B2/en not_active Expired - Fee Related
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2018
- 2018-01-31 CY CY20181100116T patent/CY1119867T1/el unknown
- 2018-02-08 JP JP2018020789A patent/JP2018104445A/ja active Pending
- 2018-02-28 ME MEP-2018-21A patent/ME02999B/me unknown