JP2013502420A5 - - Google Patents
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- Publication number
- JP2013502420A5 JP2013502420A5 JP2012525628A JP2012525628A JP2013502420A5 JP 2013502420 A5 JP2013502420 A5 JP 2013502420A5 JP 2012525628 A JP2012525628 A JP 2012525628A JP 2012525628 A JP2012525628 A JP 2012525628A JP 2013502420 A5 JP2013502420 A5 JP 2013502420A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- nkg2d
- antibody
- antigen
- binding fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23442509P | 2009-08-17 | 2009-08-17 | |
| US61/234,425 | 2009-08-17 | ||
| US30411310P | 2010-02-12 | 2010-02-12 | |
| US61/304,113 | 2010-02-12 | ||
| PCT/US2010/045627 WO2011022334A1 (en) | 2009-08-17 | 2010-08-16 | Use of nkg2d inhibitors for treating cardiovascular and metabolic diseases, such as type 2 diabetes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015151167A Division JP5978362B2 (ja) | 2009-08-17 | 2015-07-30 | 心血管疾患、および２型糖尿病などの代謝疾患の治療のためのｎｋｇ２ｄ阻害剤の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013502420A JP2013502420A (ja) | 2013-01-24 |
| JP2013502420A5 true JP2013502420A5 (https=) | 2013-08-29 |
| JP5838158B2 JP5838158B2 (ja) | 2015-12-24 |
Family
ID=43014101
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012525628A Expired - Fee Related JP5838158B2 (ja) | 2009-08-17 | 2010-08-16 | 心血管疾患、および２型糖尿病などの代謝疾患の治療のためのｎｋｇ２ｄ阻害剤の使用 |
| JP2015151167A Expired - Fee Related JP5978362B2 (ja) | 2009-08-17 | 2015-07-30 | 心血管疾患、および２型糖尿病などの代謝疾患の治療のためのｎｋｇ２ｄ阻害剤の使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015151167A Expired - Fee Related JP5978362B2 (ja) | 2009-08-17 | 2015-07-30 | 心血管疾患、および２型糖尿病などの代謝疾患の治療のためのｎｋｇ２ｄ阻害剤の使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20120148581A1 (https=) |
| EP (1) | EP2467152B1 (https=) |
| JP (2) | JP5838158B2 (https=) |
| KR (1) | KR20120090931A (https=) |
| CN (1) | CN102548573B (https=) |
| AU (1) | AU2010284428B2 (https=) |
| BR (1) | BR112012002353A2 (https=) |
| CA (1) | CA2769409A1 (https=) |
| MX (1) | MX2012001999A (https=) |
| RU (2) | RU2015138677A (https=) |
| WO (1) | WO2011022334A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2747785A4 (en) * | 2011-08-26 | 2015-04-15 | Univ California | METHOD AND COMPOSITIONS FOR TREATING RESPIRATORY DISEASES THROUGH NKG2D INHIBITION |
| EP2790696A1 (en) * | 2011-12-16 | 2014-10-22 | Atopix Therapeutics Limited | Combination of crth2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis |
| JP6200437B2 (ja) | 2012-03-16 | 2017-09-20 | ユニバーシティ ヘルス ネットワーク | Ｔｏｓｏ活性を調節するための方法および組成物 |
| US20140235552A1 (en) * | 2013-02-15 | 2014-08-21 | Claresa Levetan | Insulin independence among patients with diabetes utilizing a ppi in combination with an immune tolerance agent |
| JP2016523264A (ja) * | 2013-07-03 | 2016-08-08 | ユニバーシティ ヘルス ネットワーク | Ｔｏｓｏに対する抗体 |
| US20200157541A1 (en) * | 2018-11-19 | 2020-05-21 | Exosome Therapeutics, Inc. | Exosome loaded therapeutics for the treatment of non-alcoholic steatohepatitis, diabetes mellitus type 1 and type 2, atherosclerotic cardiovascular disease, and alpha 1 antitrypsin deficiency |
| US12312584B2 (en) | 2018-10-02 | 2025-05-27 | Exosome Therapeutics, Inc. | cGMP exosome loaded therapeutics for treating sickle cell disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004027902D1 (de) * | 2003-03-24 | 2010-08-12 | Scripps Research Inst | Dna-vakzine gegen tumorwachstum und anwendungsverfahren dafür |
| US7666417B2 (en) * | 2003-04-22 | 2010-02-23 | Fred Hutchinson Cancer Research Center | Methods and compositions for treating autoimmune diseases or conditions |
| KR100912994B1 (ko) * | 2004-04-05 | 2009-08-21 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | Ｎｋｇ２ｄ의 조절 |
| WO2008014035A2 (en) * | 2006-07-25 | 2008-01-31 | The Regents Of The University Of California | Modulation of nkg2d and method for treating or preventing solid organ allograft rejection |
| KR101615935B1 (ko) * | 2007-12-14 | 2016-04-28 | 노보 노르디스크 에이/에스 | 인간 ｎｋｇ2ｄ에 대한 항체 및 그것의 용도 |
-
2010
- 2010-08-16 CA CA2769409A patent/CA2769409A1/en not_active Abandoned
- 2010-08-16 JP JP2012525628A patent/JP5838158B2/ja not_active Expired - Fee Related
- 2010-08-16 RU RU2015138677A patent/RU2015138677A/ru unknown
- 2010-08-16 AU AU2010284428A patent/AU2010284428B2/en not_active Ceased
- 2010-08-16 KR KR1020127002101A patent/KR20120090931A/ko not_active Withdrawn
- 2010-08-16 WO PCT/US2010/045627 patent/WO2011022334A1/en not_active Ceased
- 2010-08-16 EP EP10747123.7A patent/EP2467152B1/en not_active Not-in-force
- 2010-08-16 US US13/388,023 patent/US20120148581A1/en not_active Abandoned
- 2010-08-16 CN CN201080034480.3A patent/CN102548573B/zh not_active Expired - Fee Related
- 2010-08-16 BR BR112012002353A patent/BR112012002353A2/pt not_active IP Right Cessation
- 2010-08-16 MX MX2012001999A patent/MX2012001999A/es not_active Application Discontinuation
- 2010-08-16 RU RU2012105528/15A patent/RU2566264C2/ru not_active IP Right Cessation
-
2015
- 2015-07-30 JP JP2015151167A patent/JP5978362B2/ja not_active Expired - Fee Related
- 2015-09-10 US US14/850,688 patent/US20150376281A1/en not_active Abandoned
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