JP2013500997A5 - - Google Patents
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- Publication number
- JP2013500997A5 JP2013500997A5 JP2012523088A JP2012523088A JP2013500997A5 JP 2013500997 A5 JP2013500997 A5 JP 2013500997A5 JP 2012523088 A JP2012523088 A JP 2012523088A JP 2012523088 A JP2012523088 A JP 2012523088A JP 2013500997 A5 JP2013500997 A5 JP 2013500997A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- nitro
- oxy
- oxazine
- imidazo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23042209P | 2009-07-31 | 2009-07-31 | |
| US61/230,422 | 2009-07-31 | ||
| PCT/US2010/043908 WO2011014776A1 (en) | 2009-07-31 | 2010-07-30 | Nitroimidazooxazine and nitroimidazooxazole analogues and their uses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013500997A JP2013500997A (ja) | 2013-01-10 |
| JP2013500997A5 true JP2013500997A5 (https=) | 2013-09-12 |
| JP5685254B2 JP5685254B2 (ja) | 2015-03-18 |
Family
ID=42829983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012523088A Expired - Fee Related JP5685254B2 (ja) | 2009-07-31 | 2010-07-30 | ニトロイミダゾオキサジンおよびニトロイミダゾオキサゾール・アナログならびにそれらの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8293734B2 (https=) |
| EP (1) | EP2459570B1 (https=) |
| JP (1) | JP5685254B2 (https=) |
| KR (1) | KR101738868B1 (https=) |
| CN (1) | CN102741259B (https=) |
| AU (1) | AU2010278779B2 (https=) |
| BR (1) | BR112012002214B1 (https=) |
| CA (1) | CA2769263C (https=) |
| ES (1) | ES2530266T3 (https=) |
| NZ (1) | NZ598165A (https=) |
| RU (1) | RU2540860C2 (https=) |
| WO (1) | WO2011014776A1 (https=) |
| ZA (1) | ZA201201259B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201012209D0 (en) * | 2010-05-31 | 2010-09-08 | Ge Healthcare Ltd | In vivo imaging agent |
| JP5916739B2 (ja) * | 2011-04-15 | 2016-05-11 | 大塚製薬株式会社 | ６，７−ジヒドロイミダゾ［２，１−ｂ］［１，３］オキサジン化合物 |
| JP2015006994A (ja) * | 2011-10-28 | 2015-01-15 | 大正製薬株式会社 | ジヒドロイミダゾオキサゾール誘導体 |
| KR101918469B1 (ko) * | 2012-06-04 | 2018-11-15 | 한국화학연구원 | 바이사이클릭 니트로이미다졸 유도체 또는 이들의 광학이성질체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 약제학적 조성물 |
| US10301294B2 (en) * | 2013-03-13 | 2019-05-28 | The Broad Institute Inc. | Compounds for the treatment of tuberculosis |
| CN104059082B (zh) * | 2013-03-21 | 2016-08-03 | 苏州迈泰生物技术有限公司 | 硝基咪唑杂环类化合物及其在制备治疗结核病药物中的应用 |
| KR101564425B1 (ko) | 2013-11-26 | 2015-10-30 | 한국화학연구원 | 신규한 바이사이클릭 니트로이미다졸 카바메이트 화합물, 이를 제조하는 방법 및 이를 유효성분으로 함유하는 결핵 질환의 예방 또는 치료용 약제학적 조성물 |
| TWI687409B (zh) | 2014-08-28 | 2020-03-11 | 日商大塚製藥股份有限公司 | 稠合雜環化合物 |
| KR101682356B1 (ko) | 2014-11-04 | 2016-12-06 | 한국화학연구원 | 이미다조 옥사진 유도체, 이의 약학적으로 허용 가능한 염 또는 이의 광학이성질체 및 이를 유효성분으로 함유하는 약제학적 조성물 |
| CN107207532B (zh) | 2015-01-29 | 2019-07-30 | 南京明德新药研发股份有限公司 | 抗肺结核病的硝基咪唑衍生物 |
| GB201519054D0 (en) * | 2015-10-28 | 2015-12-09 | Univ Dundee | Composition |
| JP6905506B2 (ja) | 2016-02-26 | 2021-07-21 | 大塚製薬株式会社 | ピペリジン誘導体 |
| CN108727406B (zh) * | 2017-03-28 | 2021-12-07 | 北京协和制药二厂 | 含氮杂环取代的苯并噁嗪噁唑烷酮类化合物及其制备方法和用途 |
| JP7530384B2 (ja) * | 2019-05-01 | 2024-08-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | （ｒ）－（２－メチルオキシラン－２－イル）メチル ４－ブロモベンゼンスルホネート |
| CA3236890A1 (en) | 2021-12-14 | 2023-06-22 | Boehringer Ingelheim International Gmbh | Aldosterone synthase inhibitors for treating chronic kidney disease |
| CN114249747A (zh) * | 2021-12-27 | 2022-03-29 | 苏州虞美景盛新药开发有限公司 | 一种用于治疗广泛耐药性结核病的硝基咪唑吡喃类药物的新合成工艺 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL41744A0 (en) | 1972-03-16 | 1973-05-31 | Ciba Geigy Ag | New aryl ether derivatives,their production and their use as pesticides |
| CH568715A5 (https=) | 1972-03-16 | 1975-11-14 | Ciba Geigy Ag | |
| FR2575158B1 (fr) | 1984-12-20 | 1987-10-02 | Pf Medicament | Arylalcoyloxymethyl-2 morpholines, leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central |
| SU1271861A1 (ru) * | 1985-05-07 | 1986-11-23 | Иркутский институт органической химии СО АН СССР | Способ получени 2,2-диметил-3-цианометилиденбензимидазо @ 2,1- @ -1,3-оксазолидина |
| US6087358A (en) | 1995-06-26 | 2000-07-11 | Pathogenesis Corporation | Nitro-[2,1-b]imidazopyran compounds and antibacterial uses thereof |
| US5668127A (en) * | 1995-06-26 | 1997-09-16 | Pathogenesis Corporation | Nitroimidazole antibacterial compounds and methods of use thereof |
| TWI347946B (en) * | 2002-10-11 | 2011-09-01 | Otsuka Pharma Co Ltd | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound |
| WO2005042542A1 (en) * | 2003-10-31 | 2005-05-12 | Otsuka Pharmaceutical Co., Ltd. | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis |
| JP4789966B2 (ja) | 2004-04-09 | 2011-10-12 | 大塚製薬株式会社 | 医薬組成物 |
| JP4787529B2 (ja) | 2004-04-09 | 2011-10-05 | 大塚製薬株式会社 | 医薬組成物 |
| US7115736B2 (en) | 2004-09-17 | 2006-10-03 | Daiso Co., Ltd. | Process for preparing imidazopyran derivatives |
| KR20080038369A (ko) * | 2005-07-28 | 2008-05-06 | 버텍스 파마슈티칼스 인코포레이티드 | 카스파제 억제제 프로드럭 |
| US20080275035A1 (en) * | 2005-12-23 | 2008-11-06 | Jan Jiricek | Nitroimidazole Compounds |
| US20070213341A1 (en) | 2006-03-13 | 2007-09-13 | Li Chen | Spiroindolinone derivatives |
| WO2008008480A2 (en) | 2006-07-12 | 2008-01-17 | Cumbre Pharmaceuticals Inc. | Nitroheteroaryl-containing rifamycin derivatives |
| NZ579431A (en) | 2007-03-09 | 2012-04-27 | Sanofi Aventis | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof |
| CA2712613C (en) | 2008-03-26 | 2017-02-28 | Global Alliance For Tb Drug Development | Bicyclic nitroimidazoles covalently linked to substituted phenyl oxazolidinones |
-
2010
- 2010-07-30 ES ES10740807.2T patent/ES2530266T3/es active Active
- 2010-07-30 CA CA2769263A patent/CA2769263C/en active Active
- 2010-07-30 CN CN201080041655.3A patent/CN102741259B/zh not_active Expired - Fee Related
- 2010-07-30 AU AU2010278779A patent/AU2010278779B2/en not_active Ceased
- 2010-07-30 BR BR112012002214-8A patent/BR112012002214B1/pt not_active IP Right Cessation
- 2010-07-30 NZ NZ598165A patent/NZ598165A/xx not_active IP Right Cessation
- 2010-07-30 RU RU2012107180/04A patent/RU2540860C2/ru active
- 2010-07-30 KR KR1020127005331A patent/KR101738868B1/ko not_active Expired - Fee Related
- 2010-07-30 JP JP2012523088A patent/JP5685254B2/ja not_active Expired - Fee Related
- 2010-07-30 WO PCT/US2010/043908 patent/WO2011014776A1/en not_active Ceased
- 2010-07-30 US US12/847,459 patent/US8293734B2/en not_active Expired - Fee Related
- 2010-07-30 EP EP10740807.2A patent/EP2459570B1/en active Active
-
2012
- 2012-02-20 ZA ZA2012/01259A patent/ZA201201259B/en unknown
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