JP2013500255A5 - - Google Patents

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Publication number
JP2013500255A5
JP2013500255A5 JP2012521755A JP2012521755A JP2013500255A5 JP 2013500255 A5 JP2013500255 A5 JP 2013500255A5 JP 2012521755 A JP2012521755 A JP 2012521755A JP 2012521755 A JP2012521755 A JP 2012521755A JP 2013500255 A5 JP2013500255 A5 JP 2013500255A5
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JP
Japan
Prior art keywords
lower alkyl
autophagy
cancer
cells
mbcq
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012521755A
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English (en)
Japanese (ja)
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JP2013500255A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/042759 external-priority patent/WO2011011522A2/en
Publication of JP2013500255A publication Critical patent/JP2013500255A/ja
Publication of JP2013500255A5 publication Critical patent/JP2013500255A5/ja
Pending legal-status Critical Current

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JP2012521755A 2009-07-21 2010-07-21 自食作用の強力な小分子阻害剤、およびそれの使用方法 Pending JP2013500255A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22716409P 2009-07-21 2009-07-21
US61/227,164 2009-07-21
US29673510P 2010-01-20 2010-01-20
US61/296,735 2010-01-20
PCT/US2010/042759 WO2011011522A2 (en) 2009-07-21 2010-07-21 Potent small molecule inhibitors of autophagy, and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2013500255A JP2013500255A (ja) 2013-01-07
JP2013500255A5 true JP2013500255A5 (https=) 2013-08-22

Family

ID=42829077

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012521755A Pending JP2013500255A (ja) 2009-07-21 2010-07-21 自食作用の強力な小分子阻害剤、およびそれの使用方法

Country Status (18)

Country Link
US (1) US20120258975A1 (https=)
EP (1) EP2456761A2 (https=)
JP (1) JP2013500255A (https=)
KR (1) KR20120100886A (https=)
CN (1) CN102574816A (https=)
AU (1) AU2010276223A1 (https=)
BR (1) BR112012001316A2 (https=)
CA (1) CA2767772A1 (https=)
CL (1) CL2012000163A1 (https=)
IL (1) IL217502A0 (https=)
IN (1) IN2012DN01478A (https=)
MX (1) MX2012000940A (https=)
PE (1) PE20120798A1 (https=)
PH (1) PH12012500097A1 (https=)
RU (1) RU2012105914A (https=)
SG (1) SG177486A1 (https=)
WO (1) WO2011011522A2 (https=)
ZA (1) ZA201201224B (https=)

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US20180147206A1 (en) * 2015-05-08 2018-05-31 The Board Of Regents Of The University Of Texas System Activation of neuronal store-operated calcium entry pathway for the treatment of alzheimer's disease
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US20220089609A1 (en) 2018-07-26 2022-03-24 Domain Therapeutics Substituted quinazolinone derivatives and their use as positive allosteric modulators of mglur4
CN109721554A (zh) * 2019-01-08 2019-05-07 贵州大学 一类4-氨基喹唑啉类化合物及其制备方法和应用
MX2021013662A (es) 2019-05-10 2022-03-11 Deciphera Pharmaceuticals Llc Inhibidores de la autofagia de heteroarilaminopirimidina amida y metodos de uso de estos.
EP3966207B1 (en) 2019-05-10 2023-11-01 Deciphera Pharmaceuticals, LLC Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof
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US20210215710A1 (en) * 2019-12-23 2021-07-15 University Health Network Methods for use of cdx2 as a biomarker to guide use of autophagy inhibitors in ovarian cancer
CN115485385A (zh) 2020-03-04 2022-12-16 瑞泽恩制药公司 用于使肿瘤细胞对免疫疗法敏感的方法和组合物
CN112608302B (zh) * 2020-12-28 2022-05-24 郑州大学第一附属医院 低氧还原激活靶向泛素化降解egfr蛋白的喹唑啉类衍生物及其应用
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