JP2013177430A5 - - Google Patents
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- Publication number
- JP2013177430A5 JP2013177430A5 JP2013111446A JP2013111446A JP2013177430A5 JP 2013177430 A5 JP2013177430 A5 JP 2013177430A5 JP 2013111446 A JP2013111446 A JP 2013111446A JP 2013111446 A JP2013111446 A JP 2013111446A JP 2013177430 A5 JP2013177430 A5 JP 2013177430A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cancer
- killed
- dendritic
- monocytes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 42
- 206010028980 Neoplasm Diseases 0.000 claims 41
- 201000011510 cancer Diseases 0.000 claims 41
- 210000004443 dendritic cell Anatomy 0.000 claims 29
- 238000000034 method Methods 0.000 claims 18
- 230000035939 shock Effects 0.000 claims 17
- 210000001616 monocyte Anatomy 0.000 claims 14
- 201000001441 melanoma Diseases 0.000 claims 10
- 239000000427 antigen Substances 0.000 claims 8
- 102000036639 antigens Human genes 0.000 claims 8
- 108091007433 antigens Proteins 0.000 claims 8
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 7
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims 7
- 102000006992 Interferon-alpha Human genes 0.000 claims 7
- 108010047761 Interferon-alpha Proteins 0.000 claims 7
- 238000004519 manufacturing process Methods 0.000 claims 5
- 229960005486 vaccine Drugs 0.000 claims 5
- 210000001744 T-lymphocyte Anatomy 0.000 claims 4
- 102000007557 Melanoma-Specific Antigens Human genes 0.000 claims 2
- 108010071463 Melanoma-Specific Antigens Proteins 0.000 claims 2
- 229940022399 cancer vaccine Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000010438 heat treatment Methods 0.000 claims 2
- 101100129915 Escherichia coli (strain K12) melB gene Proteins 0.000 claims 1
- 230000006044 T cell activation Effects 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 230000030741 antigen processing and presentation Effects 0.000 claims 1
- 230000001640 apoptogenic effect Effects 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 231100000433 cytotoxic Toxicity 0.000 claims 1
- 230000001472 cytotoxic effect Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000011065 in-situ storage Methods 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 230000001678 irradiating effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81791606P | 2006-06-30 | 2006-06-30 | |
| US60/817,916 | 2006-06-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518581A Division JP2009542714A (ja) | 2006-06-30 | 2007-06-29 | ＧＭ−ＣＳＦ及びインターフェロンαを用いて生成され、且つ熱処理され死滅したがん細胞を取り込んだ樹状細胞 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015207617A Division JP6134763B2 (ja) | 2006-06-30 | 2015-10-22 | ＧＭ−ＣＳＦ及びインターフェロンαを用いて生成され、且つ熱処理され死滅したがん細胞を取り込んだ樹状細胞 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013177430A JP2013177430A (ja) | 2013-09-09 |
| JP2013177430A5 true JP2013177430A5 (enExample) | 2014-06-26 |
Family
ID=38895372
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518581A Pending JP2009542714A (ja) | 2006-06-30 | 2007-06-29 | ＧＭ−ＣＳＦ及びインターフェロンαを用いて生成され、且つ熱処理され死滅したがん細胞を取り込んだ樹状細胞 |
| JP2013111446A Pending JP2013177430A (ja) | 2006-06-30 | 2013-05-28 | ＧＭ−ＣＳＦ及びインターフェロンαを用いて生成され、且つ熱処理され死滅したがん細胞を取り込んだ樹状細胞 |
| JP2015207617A Active JP6134763B2 (ja) | 2006-06-30 | 2015-10-22 | ＧＭ−ＣＳＦ及びインターフェロンαを用いて生成され、且つ熱処理され死滅したがん細胞を取り込んだ樹状細胞 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518581A Pending JP2009542714A (ja) | 2006-06-30 | 2007-06-29 | ＧＭ−ＣＳＦ及びインターフェロンαを用いて生成され、且つ熱処理され死滅したがん細胞を取り込んだ樹状細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015207617A Active JP6134763B2 (ja) | 2006-06-30 | 2015-10-22 | ＧＭ−ＣＳＦ及びインターフェロンαを用いて生成され、且つ熱処理され死滅したがん細胞を取り込んだ樹状細胞 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20080031900A1 (enExample) |
| EP (2) | EP2037957A4 (enExample) |
| JP (3) | JP2009542714A (enExample) |
| KR (1) | KR20090033375A (enExample) |
| CN (1) | CN101511384A (enExample) |
| AU (1) | AU2007269245B2 (enExample) |
| CA (1) | CA2691346A1 (enExample) |
| WO (1) | WO2008005859A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009149382A2 (en) * | 2008-06-06 | 2009-12-10 | Baylor Research Institute | Anti-cd8 antibodies block priming of cytotoxic effectors and lead to generation of regulatory cd8+t cells |
| US8728465B2 (en) * | 2008-06-17 | 2014-05-20 | Cedars-Sinai Medical Center | Use of toll-like receptor ligands as adjuvants to vaccination therapy for brain tumors |
| JP2013522309A (ja) * | 2010-03-15 | 2013-06-13 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 活性化した成熟樹状細胞を調製し保存するシステムおよび方法 |
| KR20140054140A (ko) * | 2011-07-27 | 2014-05-08 | 베일러 리서치 인스티튜트 | 췌장암에 대한 수지상 세포(ｄｃ) - 백신 치료요법 |
| SG11201401631VA (en) * | 2011-10-20 | 2014-05-29 | California Stem Cell Inc | Antigen presenting cancer vaccine with gamma interferon |
| EP2591798B1 (en) | 2011-11-09 | 2014-11-19 | Werner Lubitz | Vaccine for use in tumor immunotherapy |
| CN112646778A (zh) * | 2012-12-28 | 2021-04-13 | 阿姆弗拉公司 | 免疫原性裂解物制备方法、获得的裂解物、负载有该裂解物的树突状细胞以及药物组合物 |
| EP2787005A1 (en) | 2013-04-02 | 2014-10-08 | Activartis Biotech GmbH | Targeted cancer immune therapy |
| JP6967963B2 (ja) * | 2014-07-17 | 2021-11-17 | ブライアン ジェイ ツェルニキCZERNIECKI, Brian, J. | 複数用量注射準備済樹状細胞ワクチンの製造ならびにｈｅｒ２およびｈｅｒ３を遮断するための併用療法 |
| SG11201701728PA (en) * | 2014-09-04 | 2017-04-27 | Agency Science Tech & Res | A method to up-regulate cancer stem cell markers for the generation of antigen specific cytotoxic effector t cells |
| WO2016064899A1 (en) * | 2014-10-21 | 2016-04-28 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for antibody and antibody-loaded dendritic cell mediated therapy |
| WO2016148179A1 (ja) * | 2015-03-17 | 2016-09-22 | 国立大学法人信州大学 | Ｉｆｎを用いた非接着培養による樹状細胞の調製方法 |
| JP7019578B2 (ja) * | 2015-12-30 | 2022-02-15 | セルジーン コーポレイション | Ｔリンパ球の産生方法及びそれにより産生されるｔリンパ球 |
| EP3195878A1 (en) | 2016-01-22 | 2017-07-26 | Werner Lubitz | Bacterial ghosts for the treatment of cancer |
| BR112019000071A2 (pt) | 2016-07-07 | 2019-07-02 | Bolt Biotherapeutics Inc | conjugados adjuvantes de anticorpo |
| CN108567977B (zh) * | 2017-03-13 | 2022-04-12 | 复旦大学 | 一种免疫增强剂、免疫治疗药物组合物及其制备与用途 |
| KR20190057938A (ko) | 2017-11-21 | 2019-05-29 | 이근량 | 버스닥트의 다점 온도감지 및 광학적 경보시스템 |
| CA3087418A1 (en) * | 2018-01-18 | 2019-07-25 | University Of South Florida | Dead antigen stimulated immature heterogenous dendritic cells as therapeutics for diseases |
| WO2019204391A1 (en) * | 2018-04-19 | 2019-10-24 | Robert Caruso | Cryo-inactivated cancer cells for cancer immunotherapy |
| WO2020180648A1 (en) * | 2019-03-01 | 2020-09-10 | Gritstone Oncology, Inc. | Selection of t cell receptors |
| EP3937984A1 (en) | 2019-03-15 | 2022-01-19 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting her2 |
| JP7859015B2 (ja) * | 2021-07-15 | 2026-05-15 | 大日本印刷株式会社 | 細胞医薬品の提供方法 |
| KR20250110348A (ko) | 2022-11-23 | 2025-07-18 | 제이제이알앤디 엘엘씨 | 암 세포독성 엑소좀 제형 및 암 치료에 사용되는 방법 |
| WO2024256477A1 (en) * | 2023-06-13 | 2024-12-19 | Pdc Line Pharma Sa | Method for preparing plasmacytoid dendritic cells |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT633929E (pt) * | 1992-04-01 | 2004-07-30 | Merix Bioscience Inc | Metodo para proliferacao (in vitro) de precursores de celulas dentifricas e sua utilizacao para produzir imunogenios |
| US6821778B1 (en) | 1993-12-01 | 2004-11-23 | The Board Of Trustees Of Leland Stanford Junior University | Methods for using dendritic cells to activate gamma/delta-T cell receptor-positive T cells |
| DE69839215T2 (de) | 1997-04-15 | 2009-03-19 | Dana-Farber Cancer Institute, Inc., Boston | Dendritische zellhybride |
| CA2318557A1 (en) * | 1998-01-16 | 1999-07-22 | Biomira Usa Inc. | Patient-specific white blood cell malignancy vaccine from membrane-proteoliposomes |
| WO1999042564A2 (en) | 1998-02-20 | 1999-08-26 | The Rockefeller University | Apoptotic cell-mediated antigen presentation to dendritic cells |
| US7015205B1 (en) * | 1999-10-18 | 2006-03-21 | St. Vincent's Hospital And Medical Center Of New York | Melanoma vaccine and methods of making and using same |
| DE10041515A1 (de) * | 2000-08-24 | 2002-03-14 | Gerold Schuler | Verfahren zur Herstellung gebrauchsfertiger, Antigen-beladener oder -unbeladener, kryokonservierter reifer dendritischer Zellen |
| CA2542686A1 (en) * | 2003-10-15 | 2005-05-06 | Istituto Superiore Di Sanita | Colorectal cancer antigen |
| US20050214268A1 (en) * | 2004-03-25 | 2005-09-29 | Cavanagh William A Iii | Methods for treating tumors and cancerous tissues |
| US20060045883A1 (en) * | 2004-08-26 | 2006-03-02 | Jeffrey Molldrem | Anti-cancer vaccines |
| CN101052709B (zh) * | 2004-10-25 | 2012-06-27 | 贝勒研究院 | 装载热激黑素瘤细胞体的树突细胞 |
-
2007
- 2007-06-29 CN CNA200780032430XA patent/CN101511384A/zh active Pending
- 2007-06-29 KR KR1020097002075A patent/KR20090033375A/ko not_active Abandoned
- 2007-06-29 US US11/771,664 patent/US20080031900A1/en not_active Abandoned
- 2007-06-29 JP JP2009518581A patent/JP2009542714A/ja active Pending
- 2007-06-29 CA CA2691346A patent/CA2691346A1/en not_active Abandoned
- 2007-06-29 EP EP07812497A patent/EP2037957A4/en not_active Withdrawn
- 2007-06-29 WO PCT/US2007/072525 patent/WO2008005859A2/en not_active Ceased
- 2007-06-29 AU AU2007269245A patent/AU2007269245B2/en not_active Ceased
- 2007-06-29 EP EP13159462.4A patent/EP2630968A1/en not_active Withdrawn
-
2013
- 2013-05-28 JP JP2013111446A patent/JP2013177430A/ja active Pending
-
2015
- 2015-10-22 JP JP2015207617A patent/JP6134763B2/ja active Active
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