JP2013163105A - 無針経皮移送装置 - Google Patents
無針経皮移送装置 Download PDFInfo
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- JP2013163105A JP2013163105A JP2013113745A JP2013113745A JP2013163105A JP 2013163105 A JP2013163105 A JP 2013163105A JP 2013113745 A JP2013113745 A JP 2013113745A JP 2013113745 A JP2013113745 A JP 2013113745A JP 2013163105 A JP2013163105 A JP 2013163105A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M2005/31588—Constructional features or modes of drive mechanisms for piston rods electrically driven
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8275—Mechanical
- A61M2205/8287—Mechanical operated by an external magnetic or electromagnetic field
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/204—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically connected to external reservoirs for multiple refilling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31546—Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
- A61M5/482—Varying injection pressure, e.g. by varying speed of injection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
- A61M5/484—Regulating injection pressure
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
【解決手段】本発明の無針注射器装置は、生体の表面を介して物質を移送する無針経皮移送装置であって、前記物質を保持するチャンバと、前記貯蔵部に流体連通するノズルと、前記物質を前記ノズルの外方へ自動的に推進射出するピストンと、前記ピストンに配置されて、当該無針装置内における前記ピストンの位置を自動的に感知する位置センサと、前記チャンバに連通する、磁石およびコイルを有する制御可能なアクチュエータであって、電気的入力を受けることにより前記物質を前記チャンバから前記生体に無針移送する力を生成するアクチュエータとを備えており、前記アクチュエータは、さらに、前記位置センサによって供給されたデータに応じて制御されるように設定されている。
【選択図】図9
Description
240 電磁式アクチュエータ(可動コイルアクチュエータ)
260 位置センサ
910 ノズル
920 ピストン
950 薬剤貯蔵部
960 圧力容器(圧力源)
990 中央孔(チャンバ)
Claims (14)
- 生体の表面を介して物質を移送する無針経皮移送装置であって、
前記物質を保持するチャンバと、
前記チャンバに流体連通するノズルと、
前記チャンバに移送される前記物質を貯蔵する薬剤貯蔵部と、
前記チャンバに連通する、制御可能なローレンツ力電磁式アクチュエータであって、電気的入力を受けることにより前記物質を前記チャンバから前記生体に無針移送する力を生成するアクチュエータと、
を備えており、
前記アクチュエータは、前記電気的入力の変化に応じて可変に前記力を生成し、かつ、前記薬剤貯蔵部から前記物質を取り出し、正確に制御されて制御可能な量の前記物質を前記チャンバに移動させる、
無針経皮移送装置。 - 請求項1において、さらに、前記薬剤貯蔵部内の前記物質を自動的に加圧して、該物質を前記薬剤貯蔵部から前記チャンバ内に移送する圧力源を備える無針経皮移送装置。
- 請求項1において、前記アクチュエータが、可動コイル装置と固定磁石とを備えている無針経皮移送装置。
- 請求項1において、前記アクチュエータが、可動磁石装置と固定コイル装置とを備えている無針経皮移送装置。
- 請求項3において、前記アクチュエータにより前記コイル装置内で生成された前記力が、前記アクチュエータが受け取った前記電気的入力の変化に応じて動的に変化可能である無針経皮移送装置。
- 請求項1において、前記制御可能な電磁式アクチュエータが、二方向性のものであり、第1の電気的入力に応答して正方向の力を生成し、第2の電気的入力に応答して負方向の力を生成する無針経皮移送装置。
- 請求項1において、前記電磁式のアクチュエータが、前記物質を前記ノズルを介して押し出し、前記生体の前記表面を貫通するのに十分な速度の噴流を生成する無針経皮移送装置。
- 請求項1において、さらに、前記電気的入力の生成に使用される再充電可能な電源装置を備える無針経皮移送装置。
- 請求項1において、さらに、前記物質を前記ノズルから押し出して供給するピストンを備える無針経皮移送装置。
- 請求項1において、さらに、位置センサからのフィードバックに応じて前記アクチュエータの位置を自動的に調整するプロセッサを備える無針経皮移送装置。
- 請求項1において、さらに、前記制御可能な電磁式のアクチュエータに電気的に連通して前記電気的入力を供給するサーボコントローラを備える無針経皮移送装置。
- 請求項1において、複数の独立した無針移送を、短い時間間隔で連続的に行うことが可能である無針経皮移送装置。
- 請求項1において、さらに、自動的に充填を行う間に前記ノズルを密封する手段を備える無針経皮移送装置。
- 請求項13において、前記ノズルを密封する手段が、前記チャンバに前記物質を充填する際に閉じて、前記物質を射出する際に開く、自動的に制御される、前記ノズルに設けられたフリップキャップを有する無針経皮移送装置。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84179406P | 2006-09-01 | 2006-09-01 | |
US60/841,794 | 2006-09-01 |
Related Parent Applications (1)
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JP2009526752A Division JP5284962B2 (ja) | 2006-09-01 | 2007-08-31 | 自動充填機能を有する無針注射器 |
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JP2013163105A true JP2013163105A (ja) | 2013-08-22 |
JP5824003B2 JP5824003B2 (ja) | 2015-11-25 |
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Application Number | Title | Priority Date | Filing Date |
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JP2009526752A Active JP5284962B2 (ja) | 2006-09-01 | 2007-08-31 | 自動充填機能を有する無針注射器 |
JP2013113745A Active JP5824003B2 (ja) | 2006-09-01 | 2013-05-30 | 無針経皮移送装置 |
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JP2009526752A Active JP5284962B2 (ja) | 2006-09-01 | 2007-08-31 | 自動充填機能を有する無針注射器 |
Country Status (13)
Country | Link |
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US (1) | US8172790B2 (ja) |
EP (1) | EP2077877B1 (ja) |
JP (2) | JP5284962B2 (ja) |
KR (1) | KR20090051246A (ja) |
CN (1) | CN101588829A (ja) |
AU (1) | AU2007290354A1 (ja) |
BR (1) | BRPI0716071A2 (ja) |
CA (1) | CA2666755C (ja) |
DK (1) | DK2077877T3 (ja) |
ES (1) | ES2773842T3 (ja) |
MX (1) | MX2009002178A (ja) |
PL (1) | PL2077877T3 (ja) |
WO (1) | WO2008027579A1 (ja) |
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JP2018535007A (ja) * | 2015-11-25 | 2018-11-29 | ポータル インストルメンツ, インク.Portal Instruments, Inc. | 無針経皮注射装置 |
WO2019156237A1 (ja) * | 2018-02-09 | 2019-08-15 | 株式会社ダイセル | 注入器 |
WO2019156239A1 (ja) * | 2018-02-09 | 2019-08-15 | 株式会社ダイセル | 注入器及びそれを用いた注入対象の細胞核内への生体分子を含む溶液の注入方法 |
WO2019203584A1 (ko) * | 2018-04-20 | 2019-10-24 | 경상대학교산학협력단 | 마이크로젯 약물 전달 시스템 |
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- 2007-08-31 CN CNA2007800324136A patent/CN101588829A/zh active Pending
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- 2007-08-31 ES ES07811653T patent/ES2773842T3/es active Active
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JP2018535007A (ja) * | 2015-11-25 | 2018-11-29 | ポータル インストルメンツ, インク.Portal Instruments, Inc. | 無針経皮注射装置 |
US11980743B2 (en) | 2015-11-25 | 2024-05-14 | Portal Instruments, Inc. | Needle-free transdermal injection device |
WO2019156237A1 (ja) * | 2018-02-09 | 2019-08-15 | 株式会社ダイセル | 注入器 |
WO2019156239A1 (ja) * | 2018-02-09 | 2019-08-15 | 株式会社ダイセル | 注入器及びそれを用いた注入対象の細胞核内への生体分子を含む溶液の注入方法 |
WO2019203584A1 (ko) * | 2018-04-20 | 2019-10-24 | 경상대학교산학협력단 | 마이크로젯 약물 전달 시스템 |
Also Published As
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CA2666755C (en) | 2014-03-25 |
US8172790B2 (en) | 2012-05-08 |
US20100016827A1 (en) | 2010-01-21 |
CA2666755A1 (en) | 2008-03-06 |
JP5284962B2 (ja) | 2013-09-11 |
EP2077877B1 (en) | 2019-12-11 |
ES2773842T3 (es) | 2020-07-15 |
KR20090051246A (ko) | 2009-05-21 |
EP2077877A1 (en) | 2009-07-15 |
AU2007290354A1 (en) | 2008-03-06 |
WO2008027579A8 (en) | 2009-04-02 |
JP2010502290A (ja) | 2010-01-28 |
CN101588829A (zh) | 2009-11-25 |
WO2008027579A1 (en) | 2008-03-06 |
BRPI0716071A2 (pt) | 2013-09-24 |
PL2077877T3 (pl) | 2020-09-21 |
MX2009002178A (es) | 2009-03-11 |
JP5824003B2 (ja) | 2015-11-25 |
DK2077877T3 (da) | 2020-03-16 |
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