JP2013032405A5 - - Google Patents
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- Publication number
- JP2013032405A5 JP2013032405A5 JP2012255574A JP2012255574A JP2013032405A5 JP 2013032405 A5 JP2013032405 A5 JP 2013032405A5 JP 2012255574 A JP2012255574 A JP 2012255574A JP 2012255574 A JP2012255574 A JP 2012255574A JP 2013032405 A5 JP2013032405 A5 JP 2013032405A5
- Authority
- JP
- Japan
- Prior art keywords
- malathion
- pharmaceutical
- less
- pharmaceutical formulation
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 35
- 239000005949 Malathion Substances 0.000 claims 28
- 229960000453 malathion Drugs 0.000 claims 28
- JXSJBGJIGXNWCI-UHFFFAOYSA-N diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate Chemical compound CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC JXSJBGJIGXNWCI-UHFFFAOYSA-N 0.000 claims 24
- 238000009472 formulation Methods 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 16
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 15
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 claims 10
- 239000000825 pharmaceutical preparation Substances 0.000 claims 6
- 235000008331 Pinus X rigitaeda Nutrition 0.000 claims 5
- 235000011613 Pinus brutia Nutrition 0.000 claims 5
- 241000018646 Pinus brutia Species 0.000 claims 5
- WUOACPNHFRMFPN-UHFFFAOYSA-N alpha-terpineol Chemical compound CC1=CCC(C(C)(C)O)CC1 WUOACPNHFRMFPN-UHFFFAOYSA-N 0.000 claims 5
- SQIFACVGCPWBQZ-UHFFFAOYSA-N delta-terpineol Natural products CC(C)(O)C1CCC(=C)CC1 SQIFACVGCPWBQZ-UHFFFAOYSA-N 0.000 claims 5
- 229940116411 terpineol Drugs 0.000 claims 5
- LPQDGVLVYVULMX-UHFFFAOYSA-N isomalathion Chemical compound CCOC(=O)CC(SP(=O)(OC)SC)C(=O)OCC LPQDGVLVYVULMX-UHFFFAOYSA-N 0.000 claims 4
- -1 methyl malathion Chemical compound 0.000 claims 4
- WSORODGWGUUOBO-UHFFFAOYSA-N diethyl 2-[(dimethoxyphosphoryl)thio]succinate Chemical compound CCOC(=O)CC(SP(=O)(OC)OC)C(=O)OCC WSORODGWGUUOBO-UHFFFAOYSA-N 0.000 claims 3
- 239000000499 gel Substances 0.000 claims 3
- 239000006210 lotion Substances 0.000 claims 3
- IEPRKVQEAMIZSS-AATRIKPKSA-N diethyl fumarate Chemical compound CCOC(=O)\C=C\C(=O)OCC IEPRKVQEAMIZSS-AATRIKPKSA-N 0.000 claims 2
- 239000012535 impurity Substances 0.000 claims 2
- 239000006071 cream Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69701005P | 2005-07-06 | 2005-07-06 | |
| US60/697,010 | 2005-07-06 | ||
| US74136005P | 2005-12-01 | 2005-12-01 | |
| US60/741,360 | 2005-12-01 | ||
| US74374106P | 2006-03-24 | 2006-03-24 | |
| US60/743,741 | 2006-03-24 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008520372A Division JP5474347B2 (ja) | 2005-07-06 | 2006-07-06 | 製薬学的使用のためのマラチオンの調製方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013032405A JP2013032405A (ja) | 2013-02-14 |
| JP2013032405A5 true JP2013032405A5 (enExample) | 2013-10-31 |
Family
ID=37605209
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008520372A Expired - Fee Related JP5474347B2 (ja) | 2005-07-06 | 2006-07-06 | 製薬学的使用のためのマラチオンの調製方法 |
| JP2012255574A Pending JP2013032405A (ja) | 2005-07-06 | 2012-11-21 | 製薬学的使用のためのマラチオンの調製方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008520372A Expired - Fee Related JP5474347B2 (ja) | 2005-07-06 | 2006-07-06 | 製薬学的使用のためのマラチオンの調製方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US7560445B2 (enExample) |
| EP (1) | EP1898707A4 (enExample) |
| JP (2) | JP5474347B2 (enExample) |
| CN (2) | CN103087095A (enExample) |
| BR (1) | BRPI0612686A2 (enExample) |
| CA (1) | CA2612578A1 (enExample) |
| IL (1) | IL188512A0 (enExample) |
| WO (1) | WO2007005988A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8012498B2 (en) * | 2004-07-12 | 2011-09-06 | Sandhya Goyal | Topical gel formulation comprising organophosphate insecticide and preparation thereof |
| US7560445B2 (en) * | 2005-07-06 | 2009-07-14 | Taro Pharmaceuticals North America, Inc. | Process for preparing malathion for pharmaceutical use |
| EP2170078B1 (en) | 2007-07-09 | 2014-03-26 | Suven Life Sciences Limited | Process for the preparation of malathion and its intermediate |
| CA2977732C (en) | 2015-03-10 | 2021-02-23 | Rhodes Technologies | Acetate salt of buprenorphine and methods for preparing buprenorphine |
| HUE065408T2 (hu) * | 2018-09-27 | 2024-05-28 | Cheminova As | Malation katalizált és zöld elõállítási eljárása |
| JP6827687B1 (ja) * | 2019-11-15 | 2021-02-10 | 長谷川香料株式会社 | 香味付与剤としてのジエチル メルカプトサクシネート |
| CN111100163A (zh) * | 2019-12-30 | 2020-05-05 | 江苏腾龙生物药业有限公司 | 一种马拉硫磷原药及其制备方法 |
| CN111440211B (zh) * | 2020-04-28 | 2023-02-07 | 宁波大学科学技术学院 | 一种一锅法催化合成马拉硫磷的方法 |
| CN113372381A (zh) * | 2021-05-13 | 2021-09-10 | 西北矿冶研究院 | 烃基二硫代磷酸硫醚酯的合成方法 |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE501609A (enExample) * | 1950-03-02 | |||
| NL92943C (enExample) * | 1954-09-08 | |||
| GB834814A (en) | 1955-06-14 | 1960-05-11 | Montedison Spa | ª‡-substituted o, o-dialkyl-dithiophosphorylacetic esters and process for their preparation |
| US2879284A (en) * | 1955-08-12 | 1959-03-24 | American Cyanamid Co | Odor removal and stabilization of phosphate-containing pesticides |
| BE562612A (enExample) * | 1956-12-12 | |||
| US2962521A (en) * | 1957-11-26 | 1960-11-29 | Sumitomo Chemical Co | Method for purification of organo phosphoric acid ester |
| BE626519A (enExample) * | 1959-06-16 | |||
| GB1018460A (en) * | 1963-03-19 | 1966-01-26 | Allied Chem | Ketone adducts and their use as pesticides |
| US3352664A (en) * | 1963-12-16 | 1967-11-14 | American Cyanamid Co | Viscosity stable insecticidal and herbicidal compositions |
| US3515782A (en) * | 1964-11-27 | 1970-06-02 | American Cyanamid Co | Method for controlling insects |
| US3403201A (en) * | 1964-12-08 | 1968-09-24 | Mini Ind Chimice | Method for the preparation of o, o-dimethyl-s-(1, 2-dicarbethoxyethyl)dithiophosphate |
| US3440305A (en) * | 1965-09-30 | 1969-04-22 | American Cyanamid Co | Process for upgrading malathion |
| US3309432A (en) * | 1965-10-23 | 1967-03-14 | American Cyanamid Co | Process for upgrading thiophosphates |
| US3396223A (en) * | 1965-10-23 | 1968-08-06 | American Cyanamid Co | Insecticidal composition consisting of technical grade malathion as a carrier having dissolved therein certain other malathion-soluble technical grade synthetic organic insecticides |
| US3470272A (en) * | 1966-10-24 | 1969-09-30 | Mobil Oil Corp | Process for making phosphorothioates |
| US3463841A (en) * | 1966-11-01 | 1969-08-26 | American Cyanamid Co | Malathion manufacture |
| FR1541883A (fr) | 1966-11-01 | 1968-10-11 | American Cyanamid Co | Procédé perfectionné de préparation d'o, o-diméthylphosphorodithioate de mercaptosuccinate de diéthyle |
| JPS4429647Y1 (enExample) | 1967-12-29 | 1969-12-08 | ||
| US3671612A (en) | 1968-04-05 | 1972-06-20 | Knapsack Ag | Process for the manufacture of ammonium dialkyldithiophosphates |
| DK118016B (da) * | 1968-12-23 | 1970-06-29 | Cheminova As | Fremgangsmåde til desodorisering af eller hæmning af udviklingen af dårlig lugt i produkter, bestående af eller indeholdende organiske thiophosphater. |
| IT1006881B (it) * | 1974-01-11 | 1976-10-20 | Montedison Spa | Preparazione in continuo di acido o c dimetiltiofosforico e dei suoi sa li alcalini |
| DE2500452A1 (de) | 1974-01-11 | 1975-07-17 | Montedison Spa | Verbessertes kontinuierliches verfahren fuer die herstellung von n-monomethylamid der o,o-dimethyl-dithio- phosphorylessigsaeure als insektizid |
| JPS50106927U (enExample) | 1974-02-09 | 1975-09-02 | ||
| JPS5839837B2 (ja) * | 1979-08-09 | 1983-09-01 | 日本化学工業株式会社 | 0,0−ジアルキルジチオリン酸の精製方法 |
| FR2478644A1 (fr) * | 1980-03-21 | 1981-09-25 | Rhone Poulenc Agrochimie | Procede de preparation de malathion |
| US4520013A (en) * | 1983-03-10 | 1985-05-28 | Creative Research And Development, Inc. | Topical preparation and method for using same in treating skin disorders in animals |
| RO86214B1 (ro) | 1983-06-01 | 1985-03-01 | Alexandru Lucaciu | Procedeu de purificare a solutiei de 0,0-dimetil-s-(1,2-dicarbetox-etil)-ditiofosfat tehnic |
| RO87602B1 (ro) | 1983-08-05 | 1985-12-31 | îNTREPRINDEREA CHIMICA "SINTEZA" | Procedeu de sinteza a malationului |
| US4681964A (en) * | 1985-02-11 | 1987-07-21 | Fmc Corporation | Method of increasing the reactivity of phosphorus pentasulfide |
| JPH0429647Y2 (enExample) | 1986-07-17 | 1992-07-17 | ||
| GB8710784D0 (en) | 1987-05-07 | 1987-06-10 | Euro Celtique Sa | Tropical ectoparasiticidal composition |
| GB8821587D0 (en) | 1988-09-15 | 1988-10-12 | Euro Celtique Sa | Method for controlling lice/their ova |
| DE69231401T2 (de) * | 1991-03-01 | 2001-02-08 | Rhone-Poulenc Rorer International (Holdings) Inc., Greenville | Herstellung von faktor-ix |
| US5783202A (en) | 1995-03-14 | 1998-07-21 | Soltec Research Pty. Ltd. | Pediculicidal mousse composition for killing head lice |
| US6121478A (en) * | 1996-08-20 | 2000-09-19 | Cheminova Agro A/S | Malathion oil-in-water emulsion formulations and use of peroxide in such formulations |
| DK1021204T3 (da) | 1997-09-26 | 2006-05-08 | Noven Pharma | Bioadhæsive præparater og fremgangsmåder til topisk administration af aktive midler |
| US6596291B2 (en) | 1997-12-05 | 2003-07-22 | Thomas A. Bell | Compositions and methods for treating surfaces infected with ectoparasitic insects |
| US6103248A (en) * | 1998-05-22 | 2000-08-15 | Burkhart; Craig G. | Topical preparation and therapy for head lice |
| US6284234B1 (en) | 1998-08-04 | 2001-09-04 | Johnson & Johnson Consumer Companies, Inc. | Topical delivery systems for active agents |
| AU755192B2 (en) * | 1998-09-03 | 2002-12-05 | Solvay Fluor Und Derivate Gmbh | Purification of 1,1,1,3,3-pentafluorobutane |
| US6607716B1 (en) * | 1998-09-29 | 2003-08-19 | Tech Labs, Inc. | Pediculicidal compositions, a kit, and methods of use |
| US6524602B1 (en) | 1998-10-13 | 2003-02-25 | Craig G. Burkhart | Polymer delivery system in treatments for parasitic skin diseases |
| US20020009486A1 (en) | 1999-11-30 | 2002-01-24 | 3M Innovative Properties Company | Therapeutic agent delivery incorporating reflective optical film |
| DE10004084A1 (de) | 2000-01-31 | 2001-08-02 | Bayer Ag | Substituierte Imid-Derivate |
| AR027527A1 (es) * | 2000-02-17 | 2003-04-02 | Ecosmart Technologies Inc | Composiciones pesticidas que contienen aceites vegetales esenciales contra el piojo del cuerpo humano |
| AU4183301A (en) * | 2000-03-03 | 2001-09-17 | Biogal Gyogyszergyar | A process for purifying lovastatin and simvastatin with reduced levels of dimeric impurities |
| WO2001089503A1 (en) | 2000-05-19 | 2001-11-29 | Effcon Laboratories, Inc. | Pest treatment composition |
| BR0115100A (pt) * | 2000-11-02 | 2003-09-30 | Chromaceutical Advanced Tech | Métodos para monitorar um produto de complexo ferro-sacarìdico, para purificar uma composição, e para produzir uma composição hematìnica, complexo ferro-sacarìdico, e, complexo hematìnico reconstituìdo |
| WO2002089584A1 (en) | 2001-05-09 | 2002-11-14 | Medicis Pharmaceutical Corporation | Ectoparasiticidal compositions and methods of their use |
| GB0111314D0 (en) | 2001-05-09 | 2001-07-04 | Karobio Ab | Dermatological formulations |
| US6689394B2 (en) * | 2001-06-11 | 2004-02-10 | Schering-Plough Healthcare Products, Inc. | Removal of ectoparasites |
| CN1625394A (zh) * | 2001-12-28 | 2005-06-08 | 拜奥盖尔药厂有限公司 | 结晶和无定形莫匹罗星钙的制备方法 |
| CA2473760C (en) | 2002-02-08 | 2008-11-04 | Merck & Co., Inc. | Topical ivermectin composition |
| US7820145B2 (en) * | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US8012498B2 (en) | 2004-07-12 | 2011-09-06 | Sandhya Goyal | Topical gel formulation comprising organophosphate insecticide and preparation thereof |
| US20060121073A1 (en) * | 2004-07-12 | 2006-06-08 | Sandhya Goyal | Topical gel formulation comprising insecticide and its preparation thereof |
| US7560445B2 (en) * | 2005-07-06 | 2009-07-14 | Taro Pharmaceuticals North America, Inc. | Process for preparing malathion for pharmaceutical use |
| EP2170078B1 (en) | 2007-07-09 | 2014-03-26 | Suven Life Sciences Limited | Process for the preparation of malathion and its intermediate |
| JP5152883B1 (ja) | 2012-03-30 | 2013-02-27 | 株式会社 新倉技研 | 金属管補修工法および該工法に使用する包囲カバー |
-
2006
- 2006-06-30 US US11/427,863 patent/US7560445B2/en active Active
- 2006-07-06 CN CN2012105412140A patent/CN103087095A/zh active Pending
- 2006-07-06 BR BRPI0612686-3A patent/BRPI0612686A2/pt not_active IP Right Cessation
- 2006-07-06 JP JP2008520372A patent/JP5474347B2/ja not_active Expired - Fee Related
- 2006-07-06 CA CA002612578A patent/CA2612578A1/en not_active Abandoned
- 2006-07-06 CN CN200680024802XA patent/CN101287374B/zh not_active Expired - Fee Related
- 2006-07-06 WO PCT/US2006/026251 patent/WO2007005988A2/en not_active Ceased
- 2006-07-06 EP EP06774531A patent/EP1898707A4/en not_active Withdrawn
-
2007
- 2007-12-31 IL IL188512A patent/IL188512A0/en unknown
-
2009
- 2009-01-14 US US12/353,678 patent/US8039657B2/en active Active
- 2009-01-14 US US12/353,691 patent/US7977324B2/en active Active
-
2011
- 2011-09-22 US US13/239,750 patent/US8536155B2/en active Active
-
2012
- 2012-11-21 JP JP2012255574A patent/JP2013032405A/ja active Pending
-
2013
- 2013-08-29 US US14/013,966 patent/US8957238B2/en active Active - Reinstated
-
2015
- 2015-02-16 US US14/623,463 patent/US20150158893A1/en not_active Abandoned
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