BR0115100A - Métodos para monitorar um produto de complexo ferro-sacarìdico, para purificar uma composição, e para produzir uma composição hematìnica, complexo ferro-sacarìdico, e, complexo hematìnico reconstituìdo - Google Patents
Métodos para monitorar um produto de complexo ferro-sacarìdico, para purificar uma composição, e para produzir uma composição hematìnica, complexo ferro-sacarìdico, e, complexo hematìnico reconstituìdoInfo
- Publication number
- BR0115100A BR0115100A BR0115100-2A BR0115100A BR0115100A BR 0115100 A BR0115100 A BR 0115100A BR 0115100 A BR0115100 A BR 0115100A BR 0115100 A BR0115100 A BR 0115100A
- Authority
- BR
- Brazil
- Prior art keywords
- complex
- ferro
- saccharide
- hematinic
- monitoring
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Saccharide Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
"MéTODOS PARA MONITORAR UM PRODUTO DE COMPLEXO FERRO-SACARìDICO, PARA PURIFICAR UMA COMPOSIçãO, E PARA PRODUZIR UMA COMPOSIçãO HEMATìNICA, COMPLEXO FERRO-SACARìDICO E, COMPLEXO HEMATìNICO RECONSTITUìDO". Um método para separar e purificar as espécies hematínicas ativas presentes nos complexos ferro-sacarídicos que compreendem o complexo de gliconato férrico em sacarose, complexo de hidróxido férrico-sacarose e complexo de sacarato férrico e outros de forma e de função similares, com base na separação do complexo ferro-sacarídico de um ou mais excipientes e, preferivelmente, a liofilização do complexo ferro-sacarídico permite sua quantificação analítica; a concentração ou purificação adicional como um produto novo e útil; a preparação de formulações reprojetadas para produtos farmacêuticos novos e úteis e/ou liofilização. A capacidade de separar o complexo ferro-sacarídico responsável pela função hematínica, incluindo a sua forma liofilizada, também fornece um meio para preparar material analífico para verificar e validar a sua integridade farmacológica, a segurança para o paciente e o desempenho clínico, bem como o monitoramento analítico, padronização e inspeção de controle de qualidade nos processos de fabricação hematínicos e estabelecimento de padrões para o uso com estes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24526900P | 2000-11-02 | 2000-11-02 | |
PCT/US2001/045205 WO2002056826A2 (en) | 2000-11-02 | 2001-10-31 | Method for producing purified hematinic iron-saccharidic complex and product produced |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0115100A true BR0115100A (pt) | 2003-09-30 |
Family
ID=22925992
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0115100-2A BR0115100A (pt) | 2000-11-02 | 2001-10-31 | Métodos para monitorar um produto de complexo ferro-sacarìdico, para purificar uma composição, e para produzir uma composição hematìnica, complexo ferro-sacarìdico, e, complexo hematìnico reconstituìdo |
Country Status (12)
Country | Link |
---|---|
US (3) | US6537820B2 (pt) |
EP (2) | EP2275075A3 (pt) |
JP (2) | JP4369120B2 (pt) |
CN (1) | CN1473265B (pt) |
AU (1) | AU2002246556B2 (pt) |
BR (1) | BR0115100A (pt) |
CA (1) | CA2426799A1 (pt) |
MX (1) | MXPA03003952A (pt) |
PL (1) | PL361980A1 (pt) |
RU (1) | RU2259197C2 (pt) |
WO (1) | WO2002056826A2 (pt) |
ZA (1) | ZA200303284B (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1473265B (zh) * | 2000-11-02 | 2011-10-12 | 色品先进技术股份有限公司 | 生产纯化的补血铁-糖复合物的方法及产品的生产 |
US6929954B2 (en) * | 2000-11-02 | 2005-08-16 | Chromaceutical Advanced Technologies, Inc. | Method for producing purified hematinic iron-saccharidic complex and product produced |
US6693211B2 (en) | 2002-05-15 | 2004-02-17 | Geneva Pharmaceuticals, Inc. | Chemical process |
US7169359B2 (en) * | 2002-08-26 | 2007-01-30 | Luitpold Pharmaceuticals, Inc. | Bioequivalence test for iron-containing formulations |
DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
US20040092735A1 (en) * | 2002-11-08 | 2004-05-13 | Orchid Chemicals & Pharmaceuticals Limited | Process for the preparation of cefuroxime sodium |
US20040161852A1 (en) * | 2003-02-14 | 2004-08-19 | Anderson Christopher G. | Method of assaying an Fe-Sugar complex |
US7964568B2 (en) * | 2003-05-30 | 2011-06-21 | Chromaceutical Advanced Technologies, Inc. | Synthesis of high molecular weight iron-saccharidic complexes |
WO2005094202A2 (en) * | 2004-03-16 | 2005-10-13 | Navinta, Llc | Iron sucrose complexes and method of manufacture thereof |
WO2005094203A2 (en) * | 2004-03-16 | 2005-10-13 | Navinta, Llc | Sodium ferric gluconate complexes and method of manufacture thereof |
EP1756130A1 (de) * | 2004-05-17 | 2007-02-28 | Cilag AG | Verfahren zur herstellung von eisen (iii) gluconatkomlex |
US8158139B2 (en) * | 2004-07-12 | 2012-04-17 | Taro Pharmaceuticals North America, Inc. | Topical gel formulation comprising organophosphate insecticide and preparation thereof |
US8012498B2 (en) | 2004-07-12 | 2011-09-06 | Sandhya Goyal | Topical gel formulation comprising organophosphate insecticide and preparation thereof |
US20060046964A1 (en) * | 2004-09-02 | 2006-03-02 | Andre Morneau | Pharmaceutical formulations and methods |
CN100528237C (zh) * | 2005-04-26 | 2009-08-19 | 重庆医药工业研究院有限责任公司 | 多核的氢氧化铁-糖复合物的制备方法 |
US7560445B2 (en) | 2005-07-06 | 2009-07-14 | Taro Pharmaceuticals North America, Inc. | Process for preparing malathion for pharmaceutical use |
US20080132465A1 (en) * | 2006-12-05 | 2008-06-05 | Vincent Windisch | Apparatus and method for isolating iron components from serum |
JP5568551B2 (ja) * | 2008-05-23 | 2014-08-06 | ホスピラ・インコーポレイテツド | 包装済み鉄スクロース製品 |
EP2384361B1 (en) * | 2009-01-30 | 2018-05-30 | Ecolab INC. | Development of an aluminum hydroxycarboxylate builder |
US8202830B2 (en) | 2009-01-30 | 2012-06-19 | Ecolab Usa Inc. | Development of an aluminum hydroxydicarboxylate builder |
US8536106B2 (en) | 2010-04-14 | 2013-09-17 | Ecolab Usa Inc. | Ferric hydroxycarboxylate as a builder |
EP2690435B1 (en) * | 2011-03-22 | 2022-10-05 | Sekisui Medical Co., Ltd. | Liquid chromatography column, and method for analyzing hemoglobin |
GB201304631D0 (en) * | 2013-03-14 | 2013-05-01 | Malvern Instr Ltd | Monomer detection in protein separation |
CN103626807B (zh) * | 2013-11-20 | 2017-07-07 | 青岛国风药业股份有限公司 | 一种多糖铁复合物的制备方法及其质量检测方法 |
US20180231511A1 (en) * | 2015-08-18 | 2018-08-16 | Shimadzu Corporation | Detector for liquid chromatography |
US10258647B2 (en) | 2015-09-01 | 2019-04-16 | Particle Dynamics International, Llc | Iron-polysaccharide complexes and methods for the preparation thereof |
CN107545077A (zh) * | 2016-06-23 | 2018-01-05 | 中国石油化工股份有限公司 | 判断二元液液互溶性的方法及装置 |
WO2018186343A1 (ja) * | 2017-04-04 | 2018-10-11 | 日東電工株式会社 | 凍結乾燥体の製造方法及びその製造装置 |
CN109959628B (zh) * | 2019-04-29 | 2020-08-14 | 中南大学 | 一种基于极-光谱融合的锌溶液杂质离子浓度检测方法 |
Family Cites Families (20)
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US3275514A (en) | 1960-04-12 | 1966-09-27 | Paul D Saltman | Process for introduction of metals into the mammalian system |
US3367834A (en) | 1965-05-04 | 1968-02-06 | Dexter Martin | Method and compositions for enhancing the utilization of iron by mammals |
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US3821192A (en) * | 1971-08-18 | 1974-06-28 | Central Pharmacal Co | Process for preparing an iron-saccharide complex |
SE359447B (pt) | 1971-10-06 | 1973-09-03 | Astra Laekemedel Ab | |
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US5254474A (en) | 1991-02-25 | 1993-10-19 | The United States Of America As Represented By The Secretary Of The Army | Method of assessing thermal processing of food using intrinsically-created compounds |
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WO1997017954A1 (en) * | 1995-11-13 | 1997-05-22 | Albany Medical College | Analgesic compounds and uses thereof |
DE19734293A1 (de) * | 1997-08-08 | 1999-02-11 | Boehringer Mannheim Gmbh | Verwendung von pharmazeutischen Kombinationspräparaten enthaltend Erythropoietin und Eisenpräparate zur Behandlung von rheumatischen Erkrankungen |
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CN1257931A (zh) * | 1998-12-18 | 2000-06-28 | 吴光耀 | 一种可用于人体补铁的铁蛋白及其制备方法和应用 |
CN1473265B (zh) * | 2000-11-02 | 2011-10-12 | 色品先进技术股份有限公司 | 生产纯化的补血铁-糖复合物的方法及产品的生产 |
US7695736B2 (en) * | 2001-04-03 | 2010-04-13 | Pfizer Inc. | Reconstitutable parenteral composition |
-
2001
- 2001-10-31 CN CN018184006A patent/CN1473265B/zh not_active Expired - Fee Related
- 2001-10-31 RU RU2003116134/15A patent/RU2259197C2/ru not_active IP Right Cessation
- 2001-10-31 WO PCT/US2001/045205 patent/WO2002056826A2/en active Application Filing
- 2001-10-31 BR BR0115100-2A patent/BR0115100A/pt not_active Application Discontinuation
- 2001-10-31 EP EP10011803A patent/EP2275075A3/en not_active Withdrawn
- 2001-10-31 MX MXPA03003952A patent/MXPA03003952A/es active IP Right Grant
- 2001-10-31 EP EP01994129A patent/EP1330226A4/en not_active Withdrawn
- 2001-10-31 PL PL01361980A patent/PL361980A1/xx not_active Application Discontinuation
- 2001-10-31 US US09/999,394 patent/US6537820B2/en not_active Expired - Lifetime
- 2001-10-31 CA CA002426799A patent/CA2426799A1/en not_active Abandoned
- 2001-10-31 JP JP2002557337A patent/JP4369120B2/ja not_active Expired - Fee Related
- 2001-10-31 AU AU2002246556A patent/AU2002246556B2/en not_active Ceased
-
2003
- 2003-02-21 US US10/371,783 patent/US6773924B2/en not_active Expired - Fee Related
- 2003-04-29 ZA ZA200303284A patent/ZA200303284B/en unknown
-
2004
- 2004-06-01 US US10/858,163 patent/US6939715B2/en not_active Expired - Fee Related
-
2009
- 2009-01-19 JP JP2009008909A patent/JP2009137993A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2009137993A (ja) | 2009-06-25 |
WO2002056826A2 (en) | 2002-07-25 |
CA2426799A1 (en) | 2002-07-25 |
CN1473265B (zh) | 2011-10-12 |
JP2004526132A (ja) | 2004-08-26 |
US20020076821A1 (en) | 2002-06-20 |
US6939715B2 (en) | 2005-09-06 |
EP2275075A2 (en) | 2011-01-19 |
ZA200303284B (en) | 2003-11-04 |
RU2003116134A (ru) | 2005-01-10 |
US20030153086A1 (en) | 2003-08-14 |
EP2275075A3 (en) | 2011-08-10 |
WO2002056826A3 (en) | 2003-02-06 |
US20040220141A1 (en) | 2004-11-04 |
US6773924B2 (en) | 2004-08-10 |
EP1330226A4 (en) | 2005-11-23 |
PL361980A1 (en) | 2004-10-18 |
JP4369120B2 (ja) | 2009-11-18 |
RU2259197C2 (ru) | 2005-08-27 |
AU2002246556B2 (en) | 2006-06-01 |
MXPA03003952A (es) | 2004-09-10 |
US6537820B2 (en) | 2003-03-25 |
EP1330226A2 (en) | 2003-07-30 |
CN1473265A (zh) | 2004-02-04 |
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Legal Events
Date | Code | Title | Description |
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B15K | Others concerning applications: alteration of classification |
Free format text: ALTERADA A CLASSIFICACAO DE G01N 1/18, G01N 33/50 PARA INT.CL.2011.01 A61K 31/295, A61K 31/40 Ipc: A61K 31/295 (2006.01), A61K 31/40 (2006.01) |
|
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |