JP2012533631A5 - - Google Patents
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- Publication number
- JP2012533631A5 JP2012533631A5 JP2012521703A JP2012521703A JP2012533631A5 JP 2012533631 A5 JP2012533631 A5 JP 2012533631A5 JP 2012521703 A JP2012521703 A JP 2012521703A JP 2012521703 A JP2012521703 A JP 2012521703A JP 2012533631 A5 JP2012533631 A5 JP 2012533631A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- amino acid
- acid sequence
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22694509P | 2009-07-20 | 2009-07-20 | |
| US61/226,945 | 2009-07-20 | ||
| PCT/US2010/042423 WO2011011315A1 (en) | 2009-07-20 | 2010-07-19 | POLYPEPTIDES SELECTIVE FOR AV β3 INTEGRIN CONJUGATED WITH A VARIANT OF HUMAN SERUM ALBUMIN (HSA) AND PHARMACEUTICAL USES THEREOF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012533631A JP2012533631A (ja) | 2012-12-27 |
| JP2012533631A5 true JP2012533631A5 (https=) | 2013-09-05 |
Family
ID=43465728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012521703A Pending JP2012533631A (ja) | 2009-07-20 | 2010-07-19 | ヒト血清アルブミン（ＨＳＡ）の変異体と接合したαｖβ３インテグリンに対して選択的なポリペプチドおよびその医薬上の使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20110015130A1 (https=) |
| EP (1) | EP2456454A4 (https=) |
| JP (1) | JP2012533631A (https=) |
| KR (1) | KR20120097481A (https=) |
| CN (1) | CN102470156A (https=) |
| AR (1) | AR077764A1 (https=) |
| AU (1) | AU2010276453A1 (https=) |
| CA (1) | CA2768360A1 (https=) |
| IL (1) | IL217424A0 (https=) |
| MX (1) | MX2012000895A (https=) |
| NZ (1) | NZ597580A (https=) |
| RU (1) | RU2547592C2 (https=) |
| TW (1) | TWI557224B (https=) |
| WO (1) | WO2011011315A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101722961B1 (ko) | 2009-02-11 | 2017-04-04 | 알부메딕스 에이/에스 | 알부민 변이체 및 접합체 |
| CA2776241A1 (en) | 2009-10-30 | 2011-05-05 | Novozymes Biopharma Dk A/S | Albumin variants |
| US8357652B2 (en) * | 2009-11-20 | 2013-01-22 | Academia Sinica | Anti-tumor fibrillar human serum albumin methods and compositions |
| US9044436B2 (en) * | 2009-12-23 | 2015-06-02 | National Cheng Kung University | Compositions and methods for the treatment of angiogenesis-related eye diseases |
| CA2789337A1 (en) | 2010-02-16 | 2011-08-25 | Medimmune, Llc | Hsa-related compositions and methods of use |
| US10233228B2 (en) | 2010-04-09 | 2019-03-19 | Albumedix Ltd | Albumin derivatives and variants |
| US9045564B2 (en) | 2011-02-15 | 2015-06-02 | Medimmune, Llc | HSA-related compositions and methods of use |
| RU2650784C2 (ru) | 2011-05-05 | 2018-04-17 | Альбумедикс А/С | Варианты альбумина |
| EP2780364A2 (en) | 2011-11-18 | 2014-09-24 | Eleven Biotherapeutics, Inc. | Proteins with improved half-life and other properties |
| WO2013135896A1 (en) | 2012-03-16 | 2013-09-19 | Novozymes Biopharma Dk A/S | Albumin variants |
| MX2015005363A (es) | 2012-11-08 | 2015-11-06 | Novozymes Biopharma Dk As | Variantes de albumina. |
| US10508137B2 (en) * | 2014-08-22 | 2019-12-17 | National Cheng Kung Univeristy | Disintegrin variants and pharmaceutical uses thereof |
| ES2797901T3 (es) * | 2015-06-28 | 2020-12-04 | Allgenesis Biotherapeutics Inc | Proteínas de fusión para la inhibición de angiogénesis |
| BR102016018074A2 (pt) * | 2015-08-07 | 2021-11-16 | ALX Oncology Inc. | Construção variante de sirp-alfa, seu método de preparação e seus usos, molécula de ácido nucleico, vetor, célula hospedeira, e composição farmacêutica |
| WO2017027422A1 (en) | 2015-08-07 | 2017-02-16 | Alexo Therapeutics Inc. | Constructs having a sirp-alpha domain or variant thereof |
| WO2017029407A1 (en) | 2015-08-20 | 2017-02-23 | Albumedix A/S | Albumin variants and conjugates |
| US10336812B2 (en) | 2016-05-10 | 2019-07-02 | Janssen Biotech, Inc. | GDF15 fusion proteins and uses thereof |
| EP3870211B1 (en) | 2018-10-22 | 2025-01-08 | Janssen Sciences Ireland Unlimited Company | Glucagon like peptide 1 (glp1)-growth differentiation factor 15 (gdf15) fusion proteins and uses thereof |
| BR112021024003A2 (pt) | 2019-05-31 | 2022-04-19 | Alx Oncology Inc | Métodos de tratamento de câncer com fusão sirp alfa-fc em combinação com um inibidor de checkpoint imunológico |
| AU2020394204A1 (en) | 2019-11-27 | 2022-06-02 | ALX Oncology Inc. | Combination therapies for treating cancer |
| CN117321208A (zh) * | 2021-03-16 | 2023-12-29 | Km生物医药股份公司 | 经修饰的人血清白蛋白-硫氧还蛋白融合体 |
| JP2024520902A (ja) | 2021-05-13 | 2024-05-27 | エーエルエックス オンコロジー インコーポレイテッド | がんを治療するための併用療法 |
| WO2026022392A1 (en) * | 2024-07-26 | 2026-01-29 | Ospedale San Raffaele S.R.L. | Peptide and conjugates thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| JPS6023084B2 (ja) * | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4640835A (en) * | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4496689A (en) * | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| DE3675588D1 (de) * | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
| US4791192A (en) * | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| AU5939890A (en) * | 1989-06-07 | 1991-01-07 | Genentech Inc. | Platelet aggregation inhibitors and related molecules |
| US5525708A (en) * | 1994-03-28 | 1996-06-11 | Cytomed, Inc. | Covalent dimer of kit ligand |
| WO2003042354A2 (en) * | 2001-09-04 | 2003-05-22 | Aventis Pharmaceuticals Inc. | Abrogen polypeptides, nucleic acids encoding them and methods for using them to inhibit angiogenesis |
| CA2465891C (en) * | 2001-11-05 | 2012-05-15 | Board Of Regents, The University Of Texas System | Recombinant antibodies for the detection and neutralization of anthrax toxin |
| KR101271635B1 (ko) * | 2001-12-21 | 2013-06-12 | 휴먼 게놈 사이언시즈, 인코포레이티드 | 알부민 융합 단백질 |
| CA2489186C (en) * | 2002-06-07 | 2013-01-15 | Wisconsin Alumni Research Foundation | Chemical synthesis of reagents for peptide coupling |
| WO2005090400A1 (en) * | 2004-03-18 | 2005-09-29 | The University Court Of The University Of Glasgow | Immunosuppressive cytokine |
| WO2008056961A1 (en) * | 2006-11-10 | 2008-05-15 | Boryung Pharmaceutical Co., Ltd | A novel fusion protein, cell lines expressing the same and preparation method thereof |
| US7943728B2 (en) * | 2006-12-26 | 2011-05-17 | National Cheng Kung University | Disintegrin variants and their use in treating osteoporosis-induced bone loss and angiogenesis-related diseases |
| US8183201B2 (en) * | 2006-12-26 | 2012-05-22 | National Cheng Kung University | Methods of treating αvβ3 integrin-associated diseases by administering polypeptides selective for αvβ3 integrin |
| US9044436B2 (en) * | 2009-12-23 | 2015-06-02 | National Cheng Kung University | Compositions and methods for the treatment of angiogenesis-related eye diseases |
-
2010
- 2010-07-19 US US12/838,926 patent/US20110015130A1/en not_active Abandoned
- 2010-07-19 CA CA2768360A patent/CA2768360A1/en not_active Abandoned
- 2010-07-19 NZ NZ597580A patent/NZ597580A/xx not_active IP Right Cessation
- 2010-07-19 AR ARP100102628A patent/AR077764A1/es unknown
- 2010-07-19 AU AU2010276453A patent/AU2010276453A1/en not_active Abandoned
- 2010-07-19 RU RU2012105915/10A patent/RU2547592C2/ru not_active IP Right Cessation
- 2010-07-19 KR KR1020127004303A patent/KR20120097481A/ko not_active Withdrawn
- 2010-07-19 JP JP2012521703A patent/JP2012533631A/ja active Pending
- 2010-07-19 MX MX2012000895A patent/MX2012000895A/es not_active Application Discontinuation
- 2010-07-19 EP EP10802718A patent/EP2456454A4/en not_active Withdrawn
- 2010-07-19 CN CN2010800332967A patent/CN102470156A/zh active Pending
- 2010-07-19 TW TW099123673A patent/TWI557224B/zh active
- 2010-07-19 WO PCT/US2010/042423 patent/WO2011011315A1/en not_active Ceased
-
2012
- 2012-01-08 IL IL217424A patent/IL217424A0/en unknown
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