JP2012533631A5 - - Google Patents
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- Publication number
- JP2012533631A5 JP2012533631A5 JP2012521703A JP2012521703A JP2012533631A5 JP 2012533631 A5 JP2012533631 A5 JP 2012533631A5 JP 2012521703 A JP2012521703 A JP 2012521703A JP 2012521703 A JP2012521703 A JP 2012521703A JP 2012533631 A5 JP2012533631 A5 JP 2012533631A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- amino acid
- acid sequence
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22694509P | 2009-07-20 | 2009-07-20 | |
| US61/226,945 | 2009-07-20 | ||
| PCT/US2010/042423 WO2011011315A1 (en) | 2009-07-20 | 2010-07-19 | POLYPEPTIDES SELECTIVE FOR AV β3 INTEGRIN CONJUGATED WITH A VARIANT OF HUMAN SERUM ALBUMIN (HSA) AND PHARMACEUTICAL USES THEREOF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012533631A JP2012533631A (ja) | 2012-12-27 |
| JP2012533631A5 true JP2012533631A5 (https=) | 2013-09-05 |
Family
ID=43465728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012521703A Pending JP2012533631A (ja) | 2009-07-20 | 2010-07-19 | ヒト血清アルブミン（ＨＳＡ）の変異体と接合したαｖβ３インテグリンに対して選択的なポリペプチドおよびその医薬上の使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20110015130A1 (https=) |
| EP (1) | EP2456454A4 (https=) |
| JP (1) | JP2012533631A (https=) |
| KR (1) | KR20120097481A (https=) |
| CN (1) | CN102470156A (https=) |
| AR (1) | AR077764A1 (https=) |
| AU (1) | AU2010276453A1 (https=) |
| CA (1) | CA2768360A1 (https=) |
| IL (1) | IL217424A0 (https=) |
| MX (1) | MX2012000895A (https=) |
| NZ (1) | NZ597580A (https=) |
| RU (1) | RU2547592C2 (https=) |
| TW (1) | TWI557224B (https=) |
| WO (1) | WO2011011315A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101722961B1 (ko) | 2009-02-11 | 2017-04-04 | 알부메딕스 에이/에스 | 알부민 변이체 및 접합체 |
| EP2493921B1 (en) | 2009-10-30 | 2018-09-26 | Albumedix Ltd | Albumin variants |
| US8357652B2 (en) * | 2009-11-20 | 2013-01-22 | Academia Sinica | Anti-tumor fibrillar human serum albumin methods and compositions |
| NZ600544A (en) * | 2009-12-23 | 2014-06-27 | Univ Nat Cheng Kung | Compositions and methods for the treatment of angiogenesis-related eye diseases |
| KR20130020765A (ko) | 2010-02-16 | 2013-02-28 | 메디뮨 엘엘씨 | Ｈｓａ-관련 조성물 및 사용방법 |
| EP2556087A1 (en) | 2010-04-09 | 2013-02-13 | Novozymes Biopharma DK A/S | Albumin derivatives and variants |
| US9045564B2 (en) | 2011-02-15 | 2015-06-02 | Medimmune, Llc | HSA-related compositions and methods of use |
| CA2830660A1 (en) | 2011-05-05 | 2012-11-08 | Novozymes Biopharma Dk A/S | Albumin variants |
| EP2780364A2 (en) | 2011-11-18 | 2014-09-24 | Eleven Biotherapeutics, Inc. | Proteins with improved half-life and other properties |
| DK2825556T3 (en) | 2012-03-16 | 2018-04-16 | Albumedix As | albumin Variants |
| MX2015005363A (es) | 2012-11-08 | 2015-11-06 | Novozymes Biopharma Dk As | Variantes de albumina. |
| JP6886917B2 (ja) * | 2014-08-22 | 2021-06-16 | 國立成功大學Ｎａｔｉｏｎａｌ Ｃｈｅｎｇ Ｋｕｎｇ Ｕｎｉｖｅｒｓｉｔｙ | ロドストミンバリアント、ロドストミンバリアントをコードするポリヌクレオチド、当該ポリヌクレオチドを含む組換え宿主細胞、及びロドストミンバリアントを含む医薬組成物 |
| WO2017001990A1 (en) * | 2015-06-28 | 2017-01-05 | Allgenesis Biotherapeutics Inc. | Fusion proteins for inhibiting angiogenesis |
| AU2016304794B2 (en) | 2015-08-07 | 2021-07-15 | ALX Oncology Inc. | Constructs having a SIRP-alpha domain or variant thereof |
| EA034582B1 (ru) * | 2015-08-07 | 2020-02-21 | АЭлЭкс ОНКОЛОДЖИ ИНК. | Конструкции варианта sirp-альфа и их применение |
| JP7007261B2 (ja) | 2015-08-20 | 2022-01-24 | アルブミディクス リミティド | アルブミン変異体及びコンジュゲート |
| US10336812B2 (en) * | 2016-05-10 | 2019-07-02 | Janssen Biotech, Inc. | GDF15 fusion proteins and uses thereof |
| EA202191105A1 (ru) | 2018-10-22 | 2021-08-03 | Янссен Фармацевтика Нв | Слитые белки, полученные из глюкагоноподобного пептида 1 (glp1) и ростового фактора дифференцировки 15 (gdf15), и их применение |
| CN114126648A (zh) | 2019-05-31 | 2022-03-01 | Alx肿瘤生物技术公司 | 用SIRPα Fc融合体组合免疫检查点抑制剂治疗癌症的方法 |
| CN121243368A (zh) | 2019-11-27 | 2026-01-02 | Alx肿瘤生物技术公司 | 用于治疗癌症的组合疗法 |
| US20240148839A1 (en) * | 2021-03-16 | 2024-05-09 | Km Biologics Co., Ltd. | Modified human serum albumin-thioredoxin fusion body |
| JP2024520902A (ja) | 2021-05-13 | 2024-05-27 | エーエルエックス オンコロジー インコーポレイテッド | がんを治療するための併用療法 |
| WO2026022392A1 (en) * | 2024-07-26 | 2026-01-29 | Ospedale San Raffaele S.R.L. | Peptide and conjugates thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| JPS6023084B2 (ja) * | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4640835A (en) * | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4496689A (en) * | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| EP0206448B1 (en) * | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
| US4791192A (en) * | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| AU5939890A (en) * | 1989-06-07 | 1991-01-07 | Genentech Inc. | Platelet aggregation inhibitors and related molecules |
| US5525708A (en) * | 1994-03-28 | 1996-06-11 | Cytomed, Inc. | Covalent dimer of kit ligand |
| WO2003042354A2 (en) * | 2001-09-04 | 2003-05-22 | Aventis Pharmaceuticals Inc. | Abrogen polypeptides, nucleic acids encoding them and methods for using them to inhibit angiogenesis |
| WO2003040384A1 (en) * | 2001-11-05 | 2003-05-15 | Board Of Regents, The University Of Texas System | Recombinant antibodies for the detection and neutralization of anthrax toxin |
| KR101271635B1 (ko) * | 2001-12-21 | 2013-06-12 | 휴먼 게놈 사이언시즈, 인코포레이티드 | 알부민 융합 단백질 |
| JP2005529166A (ja) * | 2002-06-07 | 2005-09-29 | ウィスコンシン アルムニ リサーチ ファウンデーション | ペプチドカップリングのための試薬の化学合成 |
| EP1730187A1 (en) * | 2004-03-18 | 2006-12-13 | The University Court Of The University Of Glasgow | Immunosuppressive cytokine |
| WO2008056961A1 (en) * | 2006-11-10 | 2008-05-15 | Boryung Pharmaceutical Co., Ltd | A novel fusion protein, cell lines expressing the same and preparation method thereof |
| US7943728B2 (en) * | 2006-12-26 | 2011-05-17 | National Cheng Kung University | Disintegrin variants and their use in treating osteoporosis-induced bone loss and angiogenesis-related diseases |
| US8183201B2 (en) * | 2006-12-26 | 2012-05-22 | National Cheng Kung University | Methods of treating αvβ3 integrin-associated diseases by administering polypeptides selective for αvβ3 integrin |
| NZ600544A (en) * | 2009-12-23 | 2014-06-27 | Univ Nat Cheng Kung | Compositions and methods for the treatment of angiogenesis-related eye diseases |
-
2010
- 2010-07-19 KR KR1020127004303A patent/KR20120097481A/ko not_active Withdrawn
- 2010-07-19 AU AU2010276453A patent/AU2010276453A1/en not_active Abandoned
- 2010-07-19 NZ NZ597580A patent/NZ597580A/xx not_active IP Right Cessation
- 2010-07-19 RU RU2012105915/10A patent/RU2547592C2/ru not_active IP Right Cessation
- 2010-07-19 MX MX2012000895A patent/MX2012000895A/es not_active Application Discontinuation
- 2010-07-19 AR ARP100102628A patent/AR077764A1/es unknown
- 2010-07-19 WO PCT/US2010/042423 patent/WO2011011315A1/en not_active Ceased
- 2010-07-19 JP JP2012521703A patent/JP2012533631A/ja active Pending
- 2010-07-19 EP EP10802718A patent/EP2456454A4/en not_active Withdrawn
- 2010-07-19 CA CA2768360A patent/CA2768360A1/en not_active Abandoned
- 2010-07-19 TW TW099123673A patent/TWI557224B/zh active
- 2010-07-19 CN CN2010800332967A patent/CN102470156A/zh active Pending
- 2010-07-19 US US12/838,926 patent/US20110015130A1/en not_active Abandoned
-
2012
- 2012-01-08 IL IL217424A patent/IL217424A0/en unknown
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