JP2012533322A5 - - Google Patents
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- JP2012533322A5 JP2012533322A5 JP2012521710A JP2012521710A JP2012533322A5 JP 2012533322 A5 JP2012533322 A5 JP 2012533322A5 JP 2012521710 A JP2012521710 A JP 2012521710A JP 2012521710 A JP2012521710 A JP 2012521710A JP 2012533322 A5 JP2012533322 A5 JP 2012533322A5
- Authority
- JP
- Japan
- Prior art keywords
- expression
- ibd
- expression level
- determining
- level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 25
- 230000014509 gene expression Effects 0.000 claims 22
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 10
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 238000012360 testing method Methods 0.000 claims 5
- 238000001574 biopsy Methods 0.000 claims 4
- 210000001072 colon Anatomy 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 229920001184 polypeptide Polymers 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 230000002757 inflammatory effect Effects 0.000 claims 2
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 210000001815 ascending colon Anatomy 0.000 claims 1
- 210000001731 descending colon Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000011223 gene expression profiling Methods 0.000 claims 1
- 210000003405 ileum Anatomy 0.000 claims 1
- 210000001599 sigmoid colon Anatomy 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22704909P | 2009-07-20 | 2009-07-20 | |
| US61/227,049 | 2009-07-20 | ||
| US30208410P | 2010-02-05 | 2010-02-05 | |
| US61/302,084 | 2010-02-05 | ||
| PCT/US2010/042487 WO2011011339A1 (en) | 2009-07-20 | 2010-07-19 | Gene expression markers for crohn's disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012533322A JP2012533322A (ja) | 2012-12-27 |
| JP2012533322A5 true JP2012533322A5 (OSRAM) | 2013-09-05 |
Family
ID=42732741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012521710A Pending JP2012533322A (ja) | 2009-07-20 | 2010-07-19 | クローン病のための遺伝子発現マーカー |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20110033486A1 (OSRAM) |
| EP (3) | EP2456890A1 (OSRAM) |
| JP (1) | JP2012533322A (OSRAM) |
| CN (1) | CN102639710A (OSRAM) |
| AU (1) | AU2010276392A1 (OSRAM) |
| CA (1) | CA2768711A1 (OSRAM) |
| SG (1) | SG177699A1 (OSRAM) |
| WO (1) | WO2011011339A1 (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010062960A2 (en) | 2008-11-26 | 2010-06-03 | Cedars-Sinai Medical Center | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE |
| WO2010075579A2 (en) | 2008-12-24 | 2010-07-01 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (mr-uc) requiring colectomy |
| CA2830351A1 (en) | 2011-03-25 | 2012-10-04 | Cedars-Sinai Medical Center | Methods of diagnosing ulcerative colitis and crohn's disease |
| WO2014009535A2 (en) * | 2012-07-12 | 2014-01-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the survival time and treatment responsiveness of a patient suffering from a solid cancer with a signature of at least 7 genes |
| KR20230109779A (ko) | 2013-03-27 | 2023-07-20 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한섬유증 및 염증의 완화 및 반전 |
| CN105209643A (zh) * | 2013-05-17 | 2015-12-30 | 豪夫迈·罗氏有限公司 | 用于诊断和治疗炎性肠病的方法 |
| EP4105236A1 (en) | 2013-07-19 | 2022-12-21 | Cedars-Sinai Medical Center | Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease |
| MA39804A (fr) | 2014-03-27 | 2017-02-01 | Hoffmann La Roche | Méthodes permettant le diagnostic et le traitement d'une maladie inflammatoire de l'intestin |
| CA2946317A1 (en) * | 2014-05-02 | 2015-11-05 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (mruc) requiring colectomy |
| KR20180127416A (ko) | 2016-03-17 | 2018-11-28 | 세다르스-신나이 메디칼 센터 | Rnaset2를 통한 염증성 장 질환의 진단 방법 |
| CN107541790B (zh) * | 2016-06-24 | 2021-07-06 | 上海交通大学 | 一种糖基化检测的人凝集素/类人凝集素芯片及制备方法 |
| IT201600090052A1 (it) * | 2016-09-06 | 2018-03-06 | Univ Degli Studi Padova | Peptide per la diagnosi differenziale della Malattia di Crohn |
| CN106755293B (zh) * | 2016-09-23 | 2020-09-04 | 宁波大学 | 一种与肺癌辅助诊断相关的lncRNA标志物及其应用 |
| EP3522708A4 (en) | 2016-10-06 | 2020-10-07 | The Research Foundation For State University Of New York | METHODS AND KITS FOR DETECTING A FUSION MESSENGER RNA TRANSCRIPT OR A POLYPEPTIDE CODED BY THE FUSION MESSENGER RNA TRANSCRIPT |
| JP7437310B2 (ja) * | 2018-03-14 | 2024-02-22 | コーニンクレッカ フィリップス エヌ ヴェ | Ｒｎａシーケンシングデータの転写発現レベルを解釈するために局所的なユニークな特徴を使用するシステム及び方法 |
| CN108893488A (zh) * | 2018-06-19 | 2018-11-27 | 刘志强 | 一种重组质粒、dna疫苗及其制备方法和应用 |
| CN114375339A (zh) | 2019-05-14 | 2022-04-19 | 普罗米修斯生物科学公司 | Tl1a患者选择方法、系统和装置 |
| CN112578122B (zh) * | 2019-09-27 | 2022-08-02 | 成都中医药大学 | 检测粪钙卫蛋白含量的试剂在制备畸形精子症筛查试剂盒中的用途 |
| CN116168765B (zh) * | 2023-04-25 | 2023-08-18 | 山东大学 | 基于改进strobemer的基因序列生成方法及系统 |
| CN117031004B (zh) * | 2023-08-09 | 2024-10-01 | 四川省医学科学院·四川省人民医院 | 一种检测网膜素-1的试剂在制备预测或评估ibs患者生活质量的产品中的应用 |
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| FR2413974A1 (fr) | 1978-01-06 | 1979-08-03 | David Bernard | Sechoir pour feuilles imprimees par serigraphie |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4318980A (en) | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| EP0479909B1 (en) | 1989-06-29 | 1996-10-30 | Medarex, Inc. | Bispecific reagents for aids therapy |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| US5571894A (en) | 1991-02-05 | 1996-11-05 | Ciba-Geigy Corporation | Recombinant antibodies specific for a growth factor receptor |
| WO1992020373A1 (en) | 1991-05-14 | 1992-11-26 | Repligen Corporation | Heteroconjugate antibodies for treatment of hiv infection |
| EP0527283B1 (en) | 1991-08-12 | 1997-11-26 | Societe Des Produits Nestle S.A. | Food composition |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| FI941572L (fi) | 1991-10-07 | 1994-05-27 | Oncologix Inc | Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä |
| WO1993008829A1 (en) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions that mediate killing of hiv-infected cells |
| DE69233528T2 (de) | 1991-11-25 | 2006-03-16 | Enzon, Inc. | Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen |
| WO1993016185A2 (en) | 1992-02-06 | 1993-08-19 | Creative Biomolecules, Inc. | Biosynthetic binding protein for cancer marker |
| ATE244763T1 (de) | 1992-02-11 | 2003-07-15 | Cell Genesys Inc | Erzielen von homozygotem durch zielgerichtete genetische ereignisse |
| US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| EP0656064B1 (en) | 1992-08-17 | 1997-03-05 | Genentech, Inc. | Bispecific immunoadhesins |
| US6283761B1 (en) | 1992-09-08 | 2001-09-04 | Raymond Anthony Joao | Apparatus and method for processing and/or for providing healthcare information and/or healthcare-related information |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| CA2223198A1 (en) | 1997-01-14 | 1998-07-14 | Societe Des Produits Nestle S.A. | Composition and method for treatment of inflammatory conditions of the gastro-intestinal tract |
| US20050123938A1 (en) * | 1999-01-06 | 2005-06-09 | Chondrogene Limited | Method for the detection of osteoarthritis related gene transcripts in blood |
| AU2001247616B2 (en) | 2000-04-11 | 2007-06-14 | Genentech, Inc. | Multivalent antibodies and uses therefor |
| GB0130955D0 (en) | 2001-12-24 | 2002-02-13 | Cancer Res Ventures | Expression system |
| WO2003064621A2 (en) | 2002-02-01 | 2003-08-07 | Ambion, Inc. | HIGH POTENCY siRNAS FOR REDUCING THE EXPRESSION OF TARGET GENES |
| EP1534855B1 (en) * | 2002-06-25 | 2010-12-08 | Index Diagnostics AB (publ) | Method and kit for the diagnosis of ulcerative colitis |
| EP3330875B1 (en) | 2003-07-10 | 2021-12-01 | Genomic Health, Inc. | Expression profile algorithm and test for prognosing breast cancer recurrence |
| JP2005102694A (ja) * | 2003-09-10 | 2005-04-21 | Japan Science & Technology Agency | 末梢血液細胞に示差的に発現されている遺伝子群、およびそれを用いた診断方法とアッセイ方法 |
| EP1844158A4 (en) * | 2004-12-06 | 2010-09-08 | Univ Johns Hopkins | BIOMARKER FOR INFLAMMATORY ENDURANCE |
| CA2658563A1 (en) * | 2006-07-26 | 2008-01-31 | Genizon Biosciences Inc. | Crohn disease susceptibility gene |
| WO2008079406A2 (en) * | 2006-12-19 | 2008-07-03 | Genentech, Inc. | Gene expression markers for inflammatory bowel disease |
| EP2160475A4 (en) * | 2007-05-22 | 2011-02-09 | Centocor Ortho Biotech Inc | MARKERS AND METHOD FOR EVALUATING AND TREATING CROHN'S DISEASE AND ASSOCIATED DISORDERS |
| US20090155788A1 (en) * | 2007-05-22 | 2009-06-18 | Abbas Alexander R | Gene expression markers for inflammatory bowel disease |
| CA2706729A1 (en) * | 2007-11-29 | 2009-06-11 | Genentech, Inc. | Gene expression markers for inflammatory bowel disease |
| ES2391792T3 (es) * | 2007-12-20 | 2012-11-29 | Index Diagnostics Ab (Publ) | Método para la diferenciación de EII y SII y la distinción adicional entre tipos patológicos de EII |
-
2010
- 2010-07-19 WO PCT/US2010/042487 patent/WO2011011339A1/en not_active Ceased
- 2010-07-19 AU AU2010276392A patent/AU2010276392A1/en not_active Abandoned
- 2010-07-19 EP EP10737186A patent/EP2456890A1/en not_active Withdrawn
- 2010-07-19 CN CN2010800417664A patent/CN102639710A/zh active Pending
- 2010-07-19 SG SG2012003612A patent/SG177699A1/en unknown
- 2010-07-19 EP EP12182666.3A patent/EP2584049A3/en not_active Withdrawn
- 2010-07-19 CA CA2768711A patent/CA2768711A1/en not_active Abandoned
- 2010-07-19 JP JP2012521710A patent/JP2012533322A/ja active Pending
- 2010-07-19 US US12/839,340 patent/US20110033486A1/en not_active Abandoned
- 2010-07-19 EP EP13176946.5A patent/EP2757160A3/en not_active Withdrawn
-
2013
- 2013-09-06 US US14/020,628 patent/US20140154275A1/en not_active Abandoned
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