EP1844158A4 - Biomarker for inflammatory bowel disease - Google Patents

Biomarker for inflammatory bowel disease

Info

Publication number
EP1844158A4
EP1844158A4 EP05853365A EP05853365A EP1844158A4 EP 1844158 A4 EP1844158 A4 EP 1844158A4 EP 05853365 A EP05853365 A EP 05853365A EP 05853365 A EP05853365 A EP 05853365A EP 1844158 A4 EP1844158 A4 EP 1844158A4
Authority
EP
European Patent Office
Prior art keywords
biomarker
inflammatory bowel
bowel disease
disease
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05853365A
Other languages
German (de)
French (fr)
Other versions
EP1844158A2 (en
Inventor
Chakravarti Shukti
Feng Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US63366204P priority Critical
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Priority to PCT/US2005/044423 priority patent/WO2006063133A2/en
Publication of EP1844158A2 publication Critical patent/EP1844158A2/en
Publication of EP1844158A4 publication Critical patent/EP1844158A4/en
Application status is Withdrawn legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
EP05853365A 2004-12-06 2005-12-06 Biomarker for inflammatory bowel disease Withdrawn EP1844158A4 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US63366204P true 2004-12-06 2004-12-06
PCT/US2005/044423 WO2006063133A2 (en) 2004-12-06 2005-12-06 Biomarker for inflammatory bowel disease

Publications (2)

Publication Number Publication Date
EP1844158A2 EP1844158A2 (en) 2007-10-17
EP1844158A4 true EP1844158A4 (en) 2010-09-08

Family

ID=36578568

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05853365A Withdrawn EP1844158A4 (en) 2004-12-06 2005-12-06 Biomarker for inflammatory bowel disease

Country Status (2)

Country Link
EP (1) EP1844158A4 (en)
WO (1) WO2006063133A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007223881B2 (en) * 2006-03-09 2014-01-09 Alan Safdi Rifaximin anti-rectal dysfunction preparation
WO2008048986A2 (en) * 2006-10-17 2008-04-24 Children's Hospital Medical Center Gene array technique for predicting response in inflammatory bowel diseases
WO2008079406A2 (en) * 2006-12-19 2008-07-03 Genentech, Inc. Gene expression markers for inflammatory bowel disease
WO2008137383A2 (en) * 2007-04-30 2008-11-13 Centocor, Inc. Markers and methods for assessing and treating ulcerative colitis and related disorders using a 19 gene panel
EP2160475A4 (en) * 2007-05-22 2011-02-09 Centocor Ortho Biotech Inc Markers and methods for assessing and treating crohn's disease and related disorders
CN101970689A (en) * 2007-11-29 2011-02-09 健泰科生物技术公司;爱丁堡大学老学院理事会 Gene expression markers for inflammatory bowel disease
WO2008147900A2 (en) * 2007-05-22 2008-12-04 Genentech, Inc. Gene expression markers for inflammatory bowel disease
WO2009036081A1 (en) 2007-09-10 2009-03-19 University Of Kentucky Research Foundation Systems and methods for diagnosis and monitoring of bacteria-related conditions
EP2217618A2 (en) * 2007-10-02 2010-08-18 Universität zu Köln Novel marker genes for regulatory t cells from human blood
SG177699A1 (en) * 2009-07-20 2012-02-28 Genentech Inc Gene expression markers for crohn's disease
US20110301051A1 (en) * 2010-04-09 2011-12-08 Exagen Diagnostics, Inc. Biomarkers for Ulcerative Colitis and Crohn's Disease

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000014283A2 (en) * 1998-09-04 2000-03-16 Washington University Gene markers for chronic mucosal injury
US6150096A (en) * 1997-09-26 2000-11-21 Universite De Sherbrooke Molecular markers for the diagnosis of human diseases including Crohn's disease
WO2002059367A2 (en) * 2000-11-30 2002-08-01 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Diagnostic microarray for inflammatory bowel disease, crohn's disease and ulcerative colitis
WO2002077651A1 (en) * 2001-03-27 2002-10-03 Centre Hospitalier Regional Universitaire De Lille Method for diagnosing chronic intestinal inflammatory diseases
US6632617B1 (en) * 1997-05-13 2003-10-14 Incyte Corporation Tumor-associated antigen
WO2004001073A1 (en) * 2002-06-25 2003-12-31 Index Pharmaceuticals Ab Method and kit for the diagnosis of ulcerative colitis
WO2004058042A2 (en) * 2002-12-30 2004-07-15 Yeda Research And Development Co. Ltd. Methods for evaluating genetic susceptibility and therapy for chronic inflammatory diseases
WO2004065577A2 (en) * 2003-01-14 2004-08-05 Bristol-Myers Squibb Company Polynucleotides and polypeptides associated with the nf-kb pathway

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2774769B2 (en) * 1993-04-26 1998-07-09 塩野義製薬株式会社 Adrenomedullin

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632617B1 (en) * 1997-05-13 2003-10-14 Incyte Corporation Tumor-associated antigen
US6150096A (en) * 1997-09-26 2000-11-21 Universite De Sherbrooke Molecular markers for the diagnosis of human diseases including Crohn's disease
WO2000014283A2 (en) * 1998-09-04 2000-03-16 Washington University Gene markers for chronic mucosal injury
WO2002059367A2 (en) * 2000-11-30 2002-08-01 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Diagnostic microarray for inflammatory bowel disease, crohn's disease and ulcerative colitis
WO2002077651A1 (en) * 2001-03-27 2002-10-03 Centre Hospitalier Regional Universitaire De Lille Method for diagnosing chronic intestinal inflammatory diseases
WO2004001073A1 (en) * 2002-06-25 2003-12-31 Index Pharmaceuticals Ab Method and kit for the diagnosis of ulcerative colitis
WO2004058042A2 (en) * 2002-12-30 2004-07-15 Yeda Research And Development Co. Ltd. Methods for evaluating genetic susceptibility and therapy for chronic inflammatory diseases
WO2004065577A2 (en) * 2003-01-14 2004-08-05 Bristol-Myers Squibb Company Polynucleotides and polypeptides associated with the nf-kb pathway

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HINSON J P ET AL: "Adrenomedullin, a multifunctional regulatory peptide.", ENDOCRINE REVIEWS, vol. 21, no. 2, April 2000 (2000-04-01), pages 138 - 167, XP002590796, ISSN: 0163-769X *

Also Published As

Publication number Publication date
EP1844158A2 (en) 2007-10-17
WO2006063133A3 (en) 2009-04-02
WO2006063133A2 (en) 2006-06-15

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Ipc: G01N 33/53 20060101ALI20090608BHEP

Ipc: C12M 1/34 20060101ALI20090608BHEP

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