JP2012529451A5 - - Google Patents
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- Publication number
- JP2012529451A5 JP2012529451A5 JP2012514392A JP2012514392A JP2012529451A5 JP 2012529451 A5 JP2012529451 A5 JP 2012529451A5 JP 2012514392 A JP2012514392 A JP 2012514392A JP 2012514392 A JP2012514392 A JP 2012514392A JP 2012529451 A5 JP2012529451 A5 JP 2012529451A5
- Authority
- JP
- Japan
- Prior art keywords
- solid
- composition according
- solid composition
- fatty acid
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000007787 solid Substances 0.000 claims 22
- 239000008247 solid mixture Substances 0.000 claims 21
- 239000000126 substance Substances 0.000 claims 16
- 235000014113 dietary fatty acids Nutrition 0.000 claims 14
- 229930195729 fatty acid Natural products 0.000 claims 14
- 239000000194 fatty acid Substances 0.000 claims 14
- 150000004665 fatty acids Chemical class 0.000 claims 14
- 239000004480 active ingredient Substances 0.000 claims 11
- 239000003995 emulsifying agent Substances 0.000 claims 8
- 150000003626 triacylglycerols Chemical class 0.000 claims 8
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical compound NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 201000011510 cancer Diseases 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 6
- 210000003750 lower gastrointestinal tract Anatomy 0.000 claims 6
- 229940079593 drug Drugs 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 4
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims 4
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 4
- DUXYWXYOBMKGIN-UHFFFAOYSA-N trimyristin Chemical compound CCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCC DUXYWXYOBMKGIN-UHFFFAOYSA-N 0.000 claims 4
- PVNIQBQSYATKKL-UHFFFAOYSA-N tripalmitin Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCC PVNIQBQSYATKKL-UHFFFAOYSA-N 0.000 claims 4
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 claims 4
- 239000000463 material Substances 0.000 claims 3
- -1 5-ALA ester Chemical class 0.000 claims 2
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims 2
- 235000019482 Palm oil Nutrition 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 239000000853 adhesive Substances 0.000 claims 2
- 230000001070 adhesive effect Effects 0.000 claims 2
- 239000002738 chelating agent Substances 0.000 claims 2
- 229940110456 cocoa butter Drugs 0.000 claims 2
- 235000019868 cocoa butter Nutrition 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 238000013270 controlled release Methods 0.000 claims 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 238000002405 diagnostic procedure Methods 0.000 claims 2
- 239000002702 enteric coating Substances 0.000 claims 2
- 238000009505 enteric coating Methods 0.000 claims 2
- 239000003925 fat Substances 0.000 claims 2
- 235000019197 fats Nutrition 0.000 claims 2
- 229940116364 hard fat Drugs 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 claims 2
- 229960002446 octanoic acid Drugs 0.000 claims 2
- 239000003921 oil Substances 0.000 claims 2
- 235000019198 oils Nutrition 0.000 claims 2
- 239000002540 palm oil Substances 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 239000003504 photosensitizing agent Substances 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 239000002243 precursor Substances 0.000 claims 2
- 229940126589 solid medicine Drugs 0.000 claims 2
- 229940113164 trimyristin Drugs 0.000 claims 2
- 229960001947 tripalmitin Drugs 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 claims 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims 1
- 229960005150 glycerol Drugs 0.000 claims 1
- 229940049290 hydrogenated coco-glycerides Drugs 0.000 claims 1
- 239000012182 japan wax Substances 0.000 claims 1
- 229960004488 linolenic acid Drugs 0.000 claims 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000012875 nonionic emulsifier Substances 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims 1
- MAYCICSNZYXLHB-UHFFFAOYSA-N tricaproin Chemical compound CCCCCC(=O)OCC(OC(=O)CCCCC)COC(=O)CCCCC MAYCICSNZYXLHB-UHFFFAOYSA-N 0.000 claims 1
- 229940093609 tricaprylin Drugs 0.000 claims 1
- 125000005457 triglyceride group Chemical group 0.000 claims 1
- PJHKBYALYHRYSK-UHFFFAOYSA-N triheptanoin Chemical compound CCCCCCC(=O)OCC(OC(=O)CCCCCC)COC(=O)CCCCCC PJHKBYALYHRYSK-UHFFFAOYSA-N 0.000 claims 1
- 229940078561 triheptanoin Drugs 0.000 claims 1
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 claims 1
- 239000001993 wax Substances 0.000 claims 1
- 239000002023 wood Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09251538.6 | 2009-06-11 | ||
| EP09251538 | 2009-06-11 | ||
| PCT/EP2010/003531 WO2010142456A1 (en) | 2009-06-11 | 2010-06-11 | Solid compositions comprising 5-aminolevulinic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012529451A JP2012529451A (ja) | 2012-11-22 |
| JP2012529451A5 true JP2012529451A5 (OSRAM) | 2013-08-15 |
Family
ID=42628133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012514392A Ceased JP2012529451A (ja) | 2009-06-11 | 2010-06-11 | ５−アミノレブリン酸を含む固体組成物 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20120134921A1 (OSRAM) |
| EP (1) | EP2440188A1 (OSRAM) |
| JP (1) | JP2012529451A (OSRAM) |
| KR (1) | KR20140014401A (OSRAM) |
| CN (1) | CN102802612A (OSRAM) |
| AU (1) | AU2010257752B2 (OSRAM) |
| BR (1) | BRPI1011650A2 (OSRAM) |
| CA (1) | CA2763837A1 (OSRAM) |
| CL (1) | CL2011003115A1 (OSRAM) |
| CO (1) | CO6480960A2 (OSRAM) |
| CR (1) | CR20110649A (OSRAM) |
| MX (1) | MX2011013069A (OSRAM) |
| NZ (1) | NZ596946A (OSRAM) |
| PE (1) | PE20120858A1 (OSRAM) |
| RU (1) | RU2527328C2 (OSRAM) |
| SG (1) | SG176687A1 (OSRAM) |
| WO (1) | WO2010142456A1 (OSRAM) |
| ZA (1) | ZA201108850B (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013521251A (ja) | 2010-03-01 | 2013-06-10 | フォトキュア エイエスエイ | 美容組成物 |
| DE102012105512A1 (de) * | 2012-06-25 | 2014-04-24 | Hennig Arzneimittel Gmbh & Co. Kg | Arzneiform zur verlängerten Freisetzung von Wirkstoffen |
| US20140067024A1 (en) | 2012-08-30 | 2014-03-06 | Photocure Asa | Dual panel photodynamic therapy lamp |
| GB201221123D0 (en) | 2012-11-23 | 2013-01-09 | Photocure As | Device for photodynamic treatment |
| US9205070B2 (en) * | 2013-03-12 | 2015-12-08 | Applied Bioresearch, Inc. | Chelation suppository for improved drug delivery |
| JP6588193B2 (ja) * | 2014-07-31 | 2019-10-09 | カプスゲル・ベルギウム・ナムローゼ・フェンノートシャップＣａｐｓｕｇｅｌ Ｂｅｌｇｉｕｍ ＮＶ | カプセル製剤 |
| US20170216146A1 (en) * | 2014-07-31 | 2017-08-03 | Capsugel Belgium Nv | Capsule formulation |
| US11623008B2 (en) * | 2014-08-20 | 2023-04-11 | Professional Compounding Centers Of America | Excipient compositions for mucoadhesive pharmaceutical compositions including a synergistic combination of amylopectin, pullulan, hyaluronic acid, and xyloglucan |
| US9956426B2 (en) | 2015-02-26 | 2018-05-01 | Amol Punjabi | Upconverting nanoparticles |
| BR112018011965A2 (pt) * | 2015-12-17 | 2018-12-04 | Photocure Asa | método de terapia fotodinâmica (pdt) para câncer de bexiga |
| CN105481946B (zh) * | 2015-12-18 | 2019-05-21 | 浙江工商大学 | 5-氨基酮戊酸与3-羟基吡啶-4-酮的缀合物及其制备法和用途 |
| GB201522398D0 (en) | 2015-12-18 | 2016-02-03 | Photocure As | Device for photodynamic therapy |
| US10744212B2 (en) | 2016-03-14 | 2020-08-18 | General Electric Company | Topical application of nerve labeling dyes for image-guided surgery |
| GB2546128A (en) * | 2016-09-28 | 2017-07-12 | Photocure Asa | Pharamaceutical compositions comprising hexaminolevulinic acid and methods of using the same |
| KR102665545B1 (ko) | 2017-04-17 | 2024-05-13 | 더 유니버서티 오브 시카고 | 인간 건강에의 적용 및 질환의 치료를 위한 장으로의 단쇄 지방산의 전달을 위한 중합체 재료 |
| CN107434753A (zh) * | 2017-07-26 | 2017-12-05 | 南京大学 | 5‑氨基乙酰丙酸及其衍生物的泡腾片及其制备方法 |
| JP6617220B2 (ja) | 2017-12-01 | 2019-12-11 | Ｓｂｉファーマ株式会社 | 免疫チェックポイント阻害剤による抗腫瘍効果を増強するための医薬組成物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3181062B2 (ja) * | 1991-01-31 | 2001-07-03 | 帝國製薬株式会社 | 下部消化管崩壊経口製剤 |
| US6492420B2 (en) * | 1995-03-10 | 2002-12-10 | Photocure As | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| PT820432E (pt) * | 1995-03-10 | 2001-09-28 | Photocure Asa | Esteres do acido 5-aminolevulinico como agentes fotossensibilizadores em fotoquimioterapia |
| WO2000009093A1 (en) * | 1998-08-13 | 2000-02-24 | Cima Labs Inc. | Microemulsions as solid dosage forms for oral administration |
| DE60025201T2 (de) * | 1999-06-09 | 2006-06-29 | Mochida Pharmaceutical Co. Ltd. | System für wirkstofffreisetzung im unteren verdauungstrakt |
| DE10003620A1 (de) * | 2000-01-28 | 2001-08-02 | Asat Ag Applied Science & Tech | 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln |
| GB0018527D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Composition |
| GB0018528D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
| US8101209B2 (en) * | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
| US7264629B2 (en) * | 2001-11-09 | 2007-09-04 | Qlt, Inc. | Photodynamic therapy for the treatment of hair loss |
| TW577606U (en) * | 2001-11-20 | 2004-02-21 | Carry Computer Eng Co Ltd | Improved structure of all-in-one silicon disk |
| DE102005019628A1 (de) * | 2005-04-26 | 2006-11-09 | Technische Universität Braunschweig | Formulierung zur dermalen Anwendung |
| GB0609809D0 (en) * | 2006-05-17 | 2006-06-28 | Photocure Asa | Product |
| GB0724279D0 (en) * | 2007-12-12 | 2008-01-23 | Photocure Asa | Use |
-
2010
- 2010-06-11 CA CA2763837A patent/CA2763837A1/en not_active Abandoned
- 2010-06-11 PE PE2011002072A patent/PE20120858A1/es not_active Application Discontinuation
- 2010-06-11 MX MX2011013069A patent/MX2011013069A/es not_active Application Discontinuation
- 2010-06-11 NZ NZ596946A patent/NZ596946A/en not_active IP Right Cessation
- 2010-06-11 EP EP10725043A patent/EP2440188A1/en not_active Withdrawn
- 2010-06-11 CN CN2010800256075A patent/CN102802612A/zh active Pending
- 2010-06-11 SG SG2011090040A patent/SG176687A1/en unknown
- 2010-06-11 RU RU2011150920/15A patent/RU2527328C2/ru not_active IP Right Cessation
- 2010-06-11 WO PCT/EP2010/003531 patent/WO2010142456A1/en not_active Ceased
- 2010-06-11 BR BRPI1011650A patent/BRPI1011650A2/pt not_active IP Right Cessation
- 2010-06-11 US US13/377,692 patent/US20120134921A1/en not_active Abandoned
- 2010-06-11 JP JP2012514392A patent/JP2012529451A/ja not_active Ceased
- 2010-06-11 KR KR1020117030694A patent/KR20140014401A/ko not_active Withdrawn
- 2010-06-11 AU AU2010257752A patent/AU2010257752B2/en not_active Expired - Fee Related
-
2011
- 2011-12-01 ZA ZA2011/08850A patent/ZA201108850B/en unknown
- 2011-12-05 CR CR20110649A patent/CR20110649A/es unknown
- 2011-12-07 CL CL2011003115A patent/CL2011003115A1/es unknown
- 2011-12-27 CO CO11179486A patent/CO6480960A2/es not_active Application Discontinuation
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