JP2012522756A5 - - Google Patents

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Publication number
JP2012522756A5
JP2012522756A5 JP2012502710A JP2012502710A JP2012522756A5 JP 2012522756 A5 JP2012522756 A5 JP 2012522756A5 JP 2012502710 A JP2012502710 A JP 2012502710A JP 2012502710 A JP2012502710 A JP 2012502710A JP 2012522756 A5 JP2012522756 A5 JP 2012522756A5
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JP
Japan
Prior art keywords
cancer
lif
inhibitor
gene
glioma
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Granted
Application number
JP2012502710A
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English (en)
Japanese (ja)
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JP6207836B2 (ja
JP2012522756A (ja
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Publication date
Priority claimed from ES200900928A external-priority patent/ES2363358B1/es
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Publication of JP2012522756A publication Critical patent/JP2012522756A/ja
Publication of JP2012522756A5 publication Critical patent/JP2012522756A5/ja
Application granted granted Critical
Publication of JP6207836B2 publication Critical patent/JP6207836B2/ja
Active legal-status Critical Current
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JP2012502710A 2009-04-03 2010-04-06 望ましくない細胞増殖と関連する疾患の治療のための治療剤 Active JP6207836B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200900928A ES2363358B1 (es) 2009-04-03 2009-04-03 Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable.
ESP200900928 2009-04-03
PCT/EP2010/054499 WO2010115868A2 (en) 2009-04-03 2010-04-06 Therapeutic agents for the treatment of diseases associated with undesired cell proliferation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015178986A Division JP2016040255A (ja) 2009-04-03 2015-09-11 望ましくない細胞増殖と関連する疾患の治療のための治療剤

Publications (3)

Publication Number Publication Date
JP2012522756A JP2012522756A (ja) 2012-09-27
JP2012522756A5 true JP2012522756A5 (https=) 2013-05-23
JP6207836B2 JP6207836B2 (ja) 2017-10-04

Family

ID=42342718

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2012502710A Active JP6207836B2 (ja) 2009-04-03 2010-04-06 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2015178986A Pending JP2016040255A (ja) 2009-04-03 2015-09-11 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2018152551A Pending JP2019006784A (ja) 2009-04-03 2018-08-14 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2020016672A Pending JP2020090522A (ja) 2009-04-03 2020-02-04 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2021186785A Active JP7197665B2 (ja) 2009-04-03 2021-11-17 望ましくない細胞増殖と関連する疾患の治療のための治療剤

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2015178986A Pending JP2016040255A (ja) 2009-04-03 2015-09-11 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2018152551A Pending JP2019006784A (ja) 2009-04-03 2018-08-14 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2020016672A Pending JP2020090522A (ja) 2009-04-03 2020-02-04 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2021186785A Active JP7197665B2 (ja) 2009-04-03 2021-11-17 望ましくない細胞増殖と関連する疾患の治療のための治療剤

Country Status (24)

Country Link
US (4) US10100112B2 (https=)
EP (2) EP3045474B1 (https=)
JP (5) JP6207836B2 (https=)
KR (6) KR20180079470A (https=)
CN (2) CN102574918A (https=)
AU (1) AU2010233791B2 (https=)
BR (1) BRPI1015369A2 (https=)
CA (1) CA2757680C (https=)
CY (1) CY1124148T1 (https=)
DK (1) DK3045474T3 (https=)
EA (1) EA201101450A1 (https=)
ES (2) ES2363358B1 (https=)
HR (1) HRP20210352T1 (https=)
HU (1) HUE054196T2 (https=)
IL (1) IL215467A (https=)
LT (1) LT3045474T (https=)
MX (1) MX336903B (https=)
PL (1) PL3045474T3 (https=)
PT (1) PT3045474T (https=)
SG (2) SG10202010568RA (https=)
SI (1) SI3045474T1 (https=)
SM (1) SMT202100153T1 (https=)
WO (1) WO2010115868A2 (https=)
ZA (1) ZA201107215B (https=)

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EP2371860A1 (en) 2010-04-05 2011-10-05 Fundació Privada Institut d'Investigació Oncològica de Vall d'Hebron Antibody recognising human leukemia inhibitory factor (LIF) and use of anti-LIF antibodies in the treatment of diseases associated with unwanted cell proliferation
JP2015071566A (ja) * 2013-10-03 2015-04-16 住友ベークライト株式会社 Ｆｇｆ４遺伝子増幅腫瘍の医薬組成物
JP2017507969A (ja) * 2014-03-11 2017-03-23 ゴーダーヴァリ バイオリファイナリーズ リミテッド がん幹細胞標的化合物
CA3151221C (en) * 2014-06-30 2026-01-13 Altor Bioscience Corporation Il-15-based molecules and methods of use thereof
CN106687134A (zh) * 2014-09-10 2017-05-17 加利福尼亚大学董事会 通过抗hLIF抗体靶向K‑RAS介导的信号转导通路和恶性肿瘤
EP3067422B1 (en) * 2015-03-13 2024-07-31 Sabanci Üniversitesi Ct-1 inhibitors
EP3273983B1 (en) 2015-03-23 2021-05-05 Evestra, Inc. Novel cytotoxic agents that preferentially target leukemia inhibitory factor (lif) for the treatment of malignancies and as new contraceptive agents
EP3173483A1 (en) 2015-11-27 2017-05-31 Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron Agents for the treatment of diseases associated with undesired cell proliferation
US10583191B2 (en) 2016-12-19 2020-03-10 Mosaic Biomedicals Slu Antibodies against LIF and uses thereof
EP3555132B1 (en) * 2016-12-19 2023-11-15 Medimmune Limited Antibodies against lif and uses thereof
AU2019269131B2 (en) * 2018-05-14 2024-02-22 Fundació Privada Institució Catalana De Recerca I Estudis Avançats Antibodies against LIF and dosage forms thereof
MA52300A (fr) * 2018-06-18 2021-04-21 Fundacio Privada Inst Dinvestigacio Oncològica De Vall Hebron Combinaison d'inhibiteurs de lif et d'agents anti-néoplasiques à base de platine à utiliser dans le traitement du cancer
AU2019291305B2 (en) * 2018-06-18 2024-03-21 Fundacio Privada Institucio Catalana de Recerca i Estudis Avancats Methods for improving response to anti-LIF antibody treatment in individuals with cancer
WO2020056349A2 (en) * 2018-09-13 2020-03-19 Evestra, Inc. Lif/lifr antagonist oncology and nonmalignant diseases
IL287220B2 (en) * 2019-04-17 2026-03-01 Univ Hiroshima A therapeutic agent for urological cancer characterized by administering an IL-6 inhibitor in combination with a CCR2 inhibitor
CN111020030A (zh) * 2019-12-03 2020-04-17 中山大学 一种骨肉瘤干细胞标志物及其应用、试剂盒
EP3988116A1 (en) * 2020-10-23 2022-04-27 Consejo Superior De Investigaciones Científicas (CSIC) Methods and compositions for the treatment of hematologic malignancies
CN120507517B (zh) * 2025-05-21 2026-04-10 浙江省肿瘤医院 用于评估宫颈癌鳞癌和腺癌特异性的预后分子标记物及其应用

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US10583191B2 (en) * 2016-12-19 2020-03-10 Mosaic Biomedicals Slu Antibodies against LIF and uses thereof

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