JP2012521207A5 - - Google Patents
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- Publication number
- JP2012521207A5 JP2012521207A5 JP2012501286A JP2012501286A JP2012521207A5 JP 2012521207 A5 JP2012521207 A5 JP 2012521207A5 JP 2012501286 A JP2012501286 A JP 2012501286A JP 2012501286 A JP2012501286 A JP 2012501286A JP 2012521207 A5 JP2012521207 A5 JP 2012521207A5
- Authority
- JP
- Japan
- Prior art keywords
- bordetella
- polypeptide
- seq
- sequence
- cyaa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/409,324 US8017132B2 (en) | 2009-03-23 | 2009-03-23 | Mutant CyaA polypeptides and polypeptide derivatives suitable for the delivery of immunogenic molecules into a cell |
| EP09155929.4A EP2233569B1 (en) | 2009-03-23 | 2009-03-23 | Mutant CyaA polypeptides and polypeptide derivatives suitable for the delivery of immunogenic molecules into a cell |
| US12/409,324 | 2009-03-23 | ||
| EP09155929.4 | 2009-03-23 | ||
| PCT/EP2010/053795 WO2010136231A1 (en) | 2009-03-23 | 2010-03-23 | MUTANT CyaA POLYPEPTIDES AND POLYPEPTIDE DERIVATIVES SUITABLE FOR THE DELIVERY OF IMMUNOGENIC MOLECULES INTO A CELL |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012521207A JP2012521207A (ja) | 2012-09-13 |
| JP2012521207A5 true JP2012521207A5 (cg-RX-API-DMAC10.html) | 2013-05-09 |
| JP5770711B2 JP5770711B2 (ja) | 2015-08-26 |
Family
ID=42224889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012501286A Expired - Fee Related JP5770711B2 (ja) | 2009-03-23 | 2010-03-23 | 細胞中への免疫原性分子のデリバリーに適したＣｙａＡポリペプチド突然変異体及びポリペプチド誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP2411513B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP5770711B2 (cg-RX-API-DMAC10.html) |
| CN (2) | CN102439146A (cg-RX-API-DMAC10.html) |
| CA (1) | CA2755694A1 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2612945T3 (cg-RX-API-DMAC10.html) |
| RU (1) | RU2585216C2 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2010136231A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2690172A1 (en) * | 2012-07-23 | 2014-01-29 | Genticel | CYAA-based chimeric proteins comprising a heterologous polypeptide and their uses in the induction of immune responses |
| EP2975120A1 (en) | 2014-07-17 | 2016-01-20 | Institut Pasteur | Monomeric and functional adenylate cyclase CyaA toxin |
| WO2018091613A1 (en) * | 2016-11-17 | 2018-05-24 | Ecole Nationale Vétérinaire de Toulouse | Immunogenic and vaccine compositions for use against bordetella bronchiseptica infection |
| EP3323426A1 (en) * | 2016-11-17 | 2018-05-23 | Ecole Nationale Vétérinaire de Toulouse | Immunogenic and vaccine compositions for use against bordetella bronchiseptica infection |
| EP3381931A1 (en) | 2017-03-29 | 2018-10-03 | Mikrobiologicky ustav AV CR, v.v.i. | Adenylate cyclase toxoid with reduced cytolytic activity |
| DE102018215551A1 (de) | 2018-09-12 | 2020-03-12 | Virolutions Biotech Gmbh | Verfahren zur Herstellung eines antitumoralen Arenavirus sowie Arenavirusmutanten |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL86583A0 (en) * | 1987-06-04 | 1988-11-15 | Molecular Eng Ass | Vaccine containing a derivative of a microbe and method for the production thereof |
| FR2638169B1 (fr) * | 1988-10-25 | 1991-01-11 | Pasteur Institut | Derives d'adenyl cyclase et leurs utilisations biologiques |
| EP1715047A3 (en) | 1992-04-21 | 2008-08-27 | Institut Pasteur | Recombinant mutants for inducing specific immune responses |
| FR2805544B1 (fr) * | 2000-02-28 | 2004-07-16 | Pasteur Institut | Adenylcyclase recombinante et procede de tri de molecules a activite proteolytique utilisant cette adenylcyclase |
| PT1188446E (pt) * | 2000-09-15 | 2009-11-10 | Pasteur Institut | Vectores proteinácios para a distribuição da molécula a células que expressam cd11b |
| EP1489092A1 (en) * | 2003-06-18 | 2004-12-22 | Institut Pasteur | Modified Bordetella adenylate cyclase comprising or lacking CD11b/CD18 interaction domain and uses thereof |
| JP2008500271A (ja) * | 2003-10-14 | 2008-01-10 | ザ・プロウボウスト・フェロウズ・アンド・スカラーズ・オブ・ザ・カレッジ・オブ・ザ・ホリー・アンド・アンデバイデッド・トリニティ・オブ・クイーン・エリザベス・ニア・ダブリン | 免疫介在性疾患の治療および／または予防におけるアデニル酸シクラーゼ |
| PL1576967T3 (pl) * | 2004-03-18 | 2008-03-31 | Pasteur Institut | Rekombinowane białko niosące epitopy ludzkiego wirusa brodawczaka wstawione w białko cyklazy adenylanowej lub jego fragment oraz jego zastosowania terapeutyczne |
-
2010
- 2010-03-23 CN CN2010800225471A patent/CN102439146A/zh active Pending
- 2010-03-23 RU RU2011138706/10A patent/RU2585216C2/ru not_active IP Right Cessation
- 2010-03-23 CA CA2755694A patent/CA2755694A1/en not_active Abandoned
- 2010-03-23 ES ES10713874.5T patent/ES2612945T3/es active Active
- 2010-03-23 JP JP2012501286A patent/JP5770711B2/ja not_active Expired - Fee Related
- 2010-03-23 CN CN201510983155.6A patent/CN105602924A/zh active Pending
- 2010-03-23 EP EP10713874.5A patent/EP2411513B1/en active Active
- 2010-03-23 WO PCT/EP2010/053795 patent/WO2010136231A1/en not_active Ceased
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