JP2012520672A - マイクロキャリアー上の多能性(pluripotent)および多分化能(multipotent)細胞の培養 - Google Patents
マイクロキャリアー上の多能性(pluripotent)および多分化能(multipotent)細胞の培養 Download PDFInfo
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- JP2012520672A JP2012520672A JP2012500748A JP2012500748A JP2012520672A JP 2012520672 A JP2012520672 A JP 2012520672A JP 2012500748 A JP2012500748 A JP 2012500748A JP 2012500748 A JP2012500748 A JP 2012500748A JP 2012520672 A JP2012520672 A JP 2012520672A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2531/00—Microcarriers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16178609P | 2009-03-20 | 2009-03-20 | |
| US61/161,786 | 2009-03-20 | ||
| PCT/SG2010/000091 WO2010107392A1 (en) | 2009-03-20 | 2010-03-12 | Culture of pluripotent and multipotent cells on microcarriers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012520672A true JP2012520672A (ja) | 2012-09-10 |
| JP2012520672A5 JP2012520672A5 (https=) | 2013-05-02 |
Family
ID=42739870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012500748A Pending JP2012520672A (ja) | 2009-03-20 | 2010-03-12 | マイクロキャリアー上の多能性(pluripotent)および多分化能(multipotent)細胞の培養 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9150829B2 (https=) |
| EP (1) | EP2408903B1 (https=) |
| JP (1) | JP2012520672A (https=) |
| KR (1) | KR20110137805A (https=) |
| CN (1) | CN102428172A (https=) |
| SG (1) | SG174471A1 (https=) |
| WO (1) | WO2010107392A1 (https=) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016136986A1 (ja) * | 2015-02-27 | 2016-09-01 | ロート製薬株式会社 | 間葉系幹細胞培養用培地、間葉系幹細胞の培養方法及び間葉系幹細胞 |
| WO2017170849A1 (ja) * | 2016-03-30 | 2017-10-05 | 国立研究開発法人医薬基盤・健康・栄養研究所 | ナイーブ型多能性幹細胞培養用培地および多能性幹細胞の培養方法 |
| KR101845588B1 (ko) * | 2014-04-07 | 2018-04-05 | 한양대학교 산학협력단 | 적혈구계 세포의 인 비트로 확장 |
| JP2019022496A (ja) * | 2012-11-08 | 2019-02-14 | バイアサイト インク | 幹細胞集合体懸濁液組成物、その分化方法 |
| JP2023537969A (ja) * | 2020-08-10 | 2023-09-06 | リネージ セル セラピューティクス インコーポレイテッド | 胚性幹細胞増殖のための組成物及び方法 |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0222846D0 (en) * | 2002-10-03 | 2002-11-06 | Choo Yen | Cell culture |
| US9458431B2 (en) * | 2008-03-17 | 2016-10-04 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| US8895300B2 (en) | 2008-11-04 | 2014-11-25 | Viacyte, Inc. | Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof |
| JP5902092B2 (ja) | 2009-10-19 | 2016-04-13 | セルラー ダイナミクス インターナショナル, インコーポレイテッド | 心筋細胞の生成 |
| TWI419970B (zh) * | 2010-11-11 | 2013-12-21 | Univ Nat Taiwan | 使成體幹細胞產生為一球體細胞群體的方法 |
| WO2012104087A2 (en) * | 2011-02-02 | 2012-08-09 | Cellmade Sas | Cell culture device |
| WO2012149574A1 (en) * | 2011-04-29 | 2012-11-01 | Tissuetech, Inc. | Methods of isolating cells |
| WO2012166973A1 (en) * | 2011-06-01 | 2012-12-06 | Sanford-Burnham Medical Research Institute | Methods for promoting cell reprogramming |
| US8940294B2 (en) | 2012-03-02 | 2015-01-27 | Tissuetech, Inc. | Methods of isolating and culturing stem cells |
| ES2716993T3 (es) * | 2012-03-08 | 2019-06-18 | Lifecell Corp | Matrices de colágeno y tejido activadas por enzimas |
| WO2014017513A1 (ja) * | 2012-07-24 | 2014-01-30 | 日産化学工業株式会社 | 培地組成物及び当該組成物を用いた細胞又は組織の培養方法 |
| CN103031270A (zh) * | 2013-01-05 | 2013-04-10 | 绍兴文理学院 | 胆管上皮细胞的高效扩增和培养方法 |
| US9822336B2 (en) | 2013-04-16 | 2017-11-21 | Universiteit Maastricht | Blastoid, cell line based artificial blastocyst |
| CN103305453A (zh) * | 2013-05-23 | 2013-09-18 | 侯亚义 | 一种脐带间充质干细胞的微载体培养系统 |
| WO2015008275A1 (en) * | 2013-07-17 | 2015-01-22 | Kadimastem Ltd | Methods for large scale generation of stem cells |
| KR101662770B1 (ko) * | 2013-11-01 | 2016-10-06 | 건국대학교 글로컬산학협력단 | 하이브리드 줄기세포 및 만능성 줄기세포의 생존율을 높이는 방법 |
| WO2015195780A1 (en) * | 2014-06-17 | 2015-12-23 | Lieber Institute For Brain Development | Assay for cell specification in self-renewing human pluripotent stem cells |
| FR3032202B1 (fr) | 2015-02-03 | 2018-12-07 | Maco Pharma | Matrice sous forme de bille comme support cellulaire |
| CN106282094B (zh) * | 2016-10-13 | 2018-11-27 | 吴欣怡 | 人皮肤来源的前体细胞诱导分化为角膜内皮样细胞的方法 |
| EP3528630A4 (en) | 2016-10-21 | 2020-05-13 | Georgia Tech Research Corporation | METHODS AND SYSTEMS FOR T-CELL EXPANSION |
| FR3059009B1 (fr) | 2016-11-23 | 2018-12-07 | Universite de Bordeaux | Microcompartiment cellulaire et procedes de preparation |
| CN108121161A (zh) * | 2016-11-26 | 2018-06-05 | 中国科学院大连化学物理研究所 | 一种高通量形成拟胚体的微阵列芯片的制备方法与应用 |
| US20200283726A1 (en) * | 2017-11-21 | 2020-09-10 | Georgetown University | Process for continuous cell culture of gpscs |
| WO2020080561A1 (ko) * | 2018-10-15 | 2020-04-23 | (주)메디톡스 | 만능성 줄기세포 배양용 배지 및 그를 이용한 배양 방법 |
| AU2019368313A1 (en) * | 2018-10-24 | 2021-05-20 | Hebecell Corporation | Methods and systems for manufacturing hematopoietic lineage cells |
| KR102120378B1 (ko) * | 2019-07-04 | 2020-06-08 | 연세대학교 산학협력단 | 암 오가노이드의 제조 방법 및 이의 용도 |
| JP2022553792A (ja) * | 2019-10-30 | 2022-12-26 | ザ ジェネラル ホスピタル コーポレイション | Ipsc由来肺胞細胞のハイスループット培養 |
| KR102543215B1 (ko) * | 2020-02-10 | 2023-06-14 | 연세대학교 산학협력단 | 모낭조직 배양액을 포함하는 탈모의 예방 또는 치료용 조성물 |
| KR102458606B1 (ko) * | 2020-03-06 | 2022-10-25 | 경희대학교 산학협력단 | 마이크로캐리어 기반 4차원 세포 배양기 및 이를 이용한 세포배양 모니터링 방법 |
| US20230220331A1 (en) * | 2020-03-24 | 2023-07-13 | Jichi Medical University | Temporary treatment medium, treatment kit, embryogenesis arrest inhibitor, embryogenesis arrest inhibitory method, developmental engineering product preparation method, transplantation method, therapeutic method, and developmental engineering product |
| JP2023530098A (ja) * | 2020-06-11 | 2023-07-13 | メゾブラスト・インターナショナル・エスアーエールエル | 間葉系前駆細胞又は幹細胞の3d培養 |
| CN114763534B (zh) * | 2021-01-13 | 2024-04-26 | 合肥中科普瑞昇生物医药科技有限公司 | 原代胃肠间质瘤细胞培养基、培养方法及其应用 |
| CN112843338B (zh) * | 2021-02-08 | 2022-05-20 | 康膝生物医疗(深圳)有限公司 | 一种制备含胶原蛋白的间充质干细胞注射剂的方法 |
| CN113201488A (zh) * | 2021-05-13 | 2021-08-03 | 圣美基因科技(北京)有限公司 | 一种间充质干细胞大规模培养方法 |
| CN113388582A (zh) * | 2021-06-21 | 2021-09-14 | 香港再生医学有限公司 | 促使iPSC分化为外周神经干细胞的方法及培养基和系统 |
| TWI861626B (zh) * | 2021-12-21 | 2024-11-11 | 國璽幹細胞應用技術股份有限公司 | 穩定擴增富潛能幹細胞的方法 |
| WO2023123299A1 (en) * | 2021-12-31 | 2023-07-06 | Beijing Theraxyte Bioscience Co., Ltd. | Compositions and methods for culturing stem cells |
| CN115747197B (zh) * | 2023-01-06 | 2023-04-21 | 中国肉类食品综合研究中心 | 可食用3d打印生物墨水及制备方法和在培育肉中的应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2008089351A1 (en) * | 2007-01-17 | 2008-07-24 | Wisconsin Alumni Research Foundation | Improved culture of stem cells |
| WO2009006422A1 (en) * | 2007-06-29 | 2009-01-08 | Stem Cell Products, Inc. | Automated method and apparatus for embryonic stem cell culture |
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| US5795790A (en) | 1994-07-20 | 1998-08-18 | Cytotherapeutics, Inc. | Method for controlling proliferation and differentiation of cells encapsulated within bioartificial organs |
| US6387369B1 (en) | 1997-07-14 | 2002-05-14 | Osiris Therapeutics, Inc. | Cardiac muscle regeneration using mesenchymal stem cells |
| JP2005506839A (ja) | 2001-10-02 | 2005-03-10 | ベクトン・ディキンソン・アンド・カンパニー | 細胞外マトリックスおよび他の分子を使用する幹細胞の増殖および分化 |
| WO2005007799A2 (en) * | 2003-07-17 | 2005-01-27 | Gamida-Cell Ltd. | Methods for ex-vivo expanding stem/progenitor cells |
| WO2005065354A2 (en) | 2003-12-31 | 2005-07-21 | The Burnham Institute | Defined media for pluripotent stem cell culture |
| DE102004043256B4 (de) | 2004-09-07 | 2013-09-19 | Rheinische Friedrich-Wilhelms-Universität Bonn | Skalierbarer Prozess zur Kultivierung undifferenzierter Stammzellen in Suspension |
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| WO2006091921A2 (en) | 2005-02-25 | 2006-08-31 | Drexel University | Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications |
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| KR101774546B1 (ko) | 2008-11-20 | 2017-09-04 | 얀센 바이오테크 인코포레이티드 | 마이크로-캐리어 상의 만능 줄기 세포 배양 |
-
2010
- 2010-03-12 JP JP2012500748A patent/JP2012520672A/ja active Pending
- 2010-03-12 KR KR1020117024726A patent/KR20110137805A/ko not_active Withdrawn
- 2010-03-12 SG SG2011067725A patent/SG174471A1/en unknown
- 2010-03-12 CN CN2010800219292A patent/CN102428172A/zh active Pending
- 2010-03-12 EP EP10753781.3A patent/EP2408903B1/en active Active
- 2010-03-12 US US13/257,674 patent/US9150829B2/en active Active
- 2010-03-12 WO PCT/SG2010/000091 patent/WO2010107392A1/en not_active Ceased
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Non-Patent Citations (2)
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| JPN6014031554; David A. Classen, et al: Molecular Reproduction and Development Vol.76, 20090220, p.722-732 * |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019022496A (ja) * | 2012-11-08 | 2019-02-14 | バイアサイト インク | 幹細胞集合体懸濁液組成物、その分化方法 |
| JP2021007393A (ja) * | 2012-11-08 | 2021-01-28 | バイアサイト インク | 幹細胞集合体懸濁液組成物、その分化方法 |
| JP2023075135A (ja) * | 2012-11-08 | 2023-05-30 | バイアサイト インク | 霊長類多能性幹細胞集合体懸濁培養物及びその分化方法 |
| JP7580508B2 (ja) | 2012-11-08 | 2024-11-11 | ヴィアサイト,インコーポレイテッド | 霊長類多能性幹細胞集合体懸濁培養物及びその分化方法 |
| JP2025028837A (ja) * | 2012-11-08 | 2025-03-05 | ヴィアサイト,インコーポレイテッド | 霊長類多能性幹細胞集合体懸濁培養物及びその分化方法 |
| KR101845588B1 (ko) * | 2014-04-07 | 2018-04-05 | 한양대학교 산학협력단 | 적혈구계 세포의 인 비트로 확장 |
| US10273455B2 (en) | 2014-04-07 | 2019-04-30 | Iucf-Hyu | In vitro expansion of erythroid cells |
| WO2016136986A1 (ja) * | 2015-02-27 | 2016-09-01 | ロート製薬株式会社 | 間葉系幹細胞培養用培地、間葉系幹細胞の培養方法及び間葉系幹細胞 |
| JPWO2016136986A1 (ja) * | 2015-02-27 | 2017-12-07 | ロート製薬株式会社 | 間葉系幹細胞培養用培地、間葉系幹細胞の培養方法及び間葉系幹細胞 |
| WO2017170849A1 (ja) * | 2016-03-30 | 2017-10-05 | 国立研究開発法人医薬基盤・健康・栄養研究所 | ナイーブ型多能性幹細胞培養用培地および多能性幹細胞の培養方法 |
| JPWO2017170849A1 (ja) * | 2016-03-30 | 2019-05-16 | 協和発酵バイオ株式会社 | ナイーブ型多能性幹細胞培養用培地および多能性幹細胞の培養方法 |
| JP2023537969A (ja) * | 2020-08-10 | 2023-09-06 | リネージ セル セラピューティクス インコーポレイテッド | 胚性幹細胞増殖のための組成物及び方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2408903A4 (en) | 2013-02-20 |
| WO2010107392A1 (en) | 2010-09-23 |
| EP2408903B1 (en) | 2014-08-06 |
| CN102428172A (zh) | 2012-04-25 |
| SG174471A1 (en) | 2011-10-28 |
| US20120009645A1 (en) | 2012-01-12 |
| US9150829B2 (en) | 2015-10-06 |
| KR20110137805A (ko) | 2011-12-23 |
| EP2408903A1 (en) | 2012-01-25 |
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