JP2012520672A - マイクロキャリアー上の多能性(pluripotent)および多分化能(multipotent)細胞の培養 - Google Patents
マイクロキャリアー上の多能性(pluripotent)および多分化能(multipotent)細胞の培養 Download PDFInfo
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- JP2012520672A JP2012520672A JP2012500748A JP2012500748A JP2012520672A JP 2012520672 A JP2012520672 A JP 2012520672A JP 2012500748 A JP2012500748 A JP 2012500748A JP 2012500748 A JP2012500748 A JP 2012500748A JP 2012520672 A JP2012520672 A JP 2012520672A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2531/00—Microcarriers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16178609P | 2009-03-20 | 2009-03-20 | |
| US61/161,786 | 2009-03-20 | ||
| PCT/SG2010/000091 WO2010107392A1 (en) | 2009-03-20 | 2010-03-12 | Culture of pluripotent and multipotent cells on microcarriers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012520672A true JP2012520672A (ja) | 2012-09-10 |
| JP2012520672A5 JP2012520672A5 (enExample) | 2013-05-02 |
Family
ID=42739870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012500748A Pending JP2012520672A (ja) | 2009-03-20 | 2010-03-12 | マイクロキャリアー上の多能性(pluripotent)および多分化能(multipotent)細胞の培養 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9150829B2 (enExample) |
| EP (1) | EP2408903B1 (enExample) |
| JP (1) | JP2012520672A (enExample) |
| KR (1) | KR20110137805A (enExample) |
| CN (1) | CN102428172A (enExample) |
| SG (1) | SG174471A1 (enExample) |
| WO (1) | WO2010107392A1 (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016136986A1 (ja) * | 2015-02-27 | 2016-09-01 | ロート製薬株式会社 | 間葉系幹細胞培養用培地、間葉系幹細胞の培養方法及び間葉系幹細胞 |
| WO2017170849A1 (ja) * | 2016-03-30 | 2017-10-05 | 国立研究開発法人医薬基盤・健康・栄養研究所 | ナイーブ型多能性幹細胞培養用培地および多能性幹細胞の培養方法 |
| KR101845588B1 (ko) * | 2014-04-07 | 2018-04-05 | 한양대학교 산학협력단 | 적혈구계 세포의 인 비트로 확장 |
| JP2019022496A (ja) * | 2012-11-08 | 2019-02-14 | バイアサイト インク | 幹細胞集合体懸濁液組成物、その分化方法 |
| JP2023537969A (ja) * | 2020-08-10 | 2023-09-06 | リネージ セル セラピューティクス インコーポレイテッド | 胚性幹細胞増殖のための組成物及び方法 |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0222846D0 (en) | 2002-10-03 | 2002-11-06 | Choo Yen | Cell culture |
| US9458431B2 (en) * | 2008-03-17 | 2016-10-04 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| US8895300B2 (en) | 2008-11-04 | 2014-11-25 | Viacyte, Inc. | Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof |
| CA2777552C (en) | 2009-10-19 | 2019-05-21 | Cellular Dynamics International, Inc. | Cardiomyocyte production |
| TWI419970B (zh) * | 2010-11-11 | 2013-12-21 | Univ Nat Taiwan | 使成體幹細胞產生為一球體細胞群體的方法 |
| WO2012104087A2 (en) * | 2011-02-02 | 2012-08-09 | Cellmade Sas | Cell culture device |
| WO2012149574A1 (en) * | 2011-04-29 | 2012-11-01 | Tissuetech, Inc. | Methods of isolating cells |
| US20130064799A1 (en) | 2011-06-01 | 2013-03-14 | Tariq M. Rana | Methods for promoting cell reprogramming |
| US8940294B2 (en) | 2012-03-02 | 2015-01-27 | Tissuetech, Inc. | Methods of isolating and culturing stem cells |
| EP2822610B1 (en) * | 2012-03-08 | 2018-12-26 | LifeCell Corporation | Enzyme-activated collagen and tissue matrices |
| EP3409761B1 (en) * | 2012-07-24 | 2025-09-03 | Nissan Chemical Corporation | Culture medium composition, and method for culturing cell or tissue using said composition |
| CN103031270A (zh) * | 2013-01-05 | 2013-04-10 | 绍兴文理学院 | 胆管上皮细胞的高效扩增和培养方法 |
| JP6689498B2 (ja) * | 2013-04-16 | 2020-04-28 | イーエムべーアー−インスティツート フューア モレクラー ビオテクノロギー ゲーエムベーハー | ブラストイド、細胞株に基づく人工胚盤胞 |
| CN103305453A (zh) * | 2013-05-23 | 2013-09-18 | 侯亚义 | 一种脐带间充质干细胞的微载体培养系统 |
| WO2015008275A1 (en) * | 2013-07-17 | 2015-01-22 | Kadimastem Ltd | Methods for large scale generation of stem cells |
| KR101662770B1 (ko) * | 2013-11-01 | 2016-10-06 | 건국대학교 글로컬산학협력단 | 하이브리드 줄기세포 및 만능성 줄기세포의 생존율을 높이는 방법 |
| WO2015195780A1 (en) * | 2014-06-17 | 2015-12-23 | Lieber Institute For Brain Development | Assay for cell specification in self-renewing human pluripotent stem cells |
| FR3032202B1 (fr) | 2015-02-03 | 2018-12-07 | Maco Pharma | Matrice sous forme de bille comme support cellulaire |
| CN106282094B (zh) * | 2016-10-13 | 2018-11-27 | 吴欣怡 | 人皮肤来源的前体细胞诱导分化为角膜内皮样细胞的方法 |
| FR3059009B1 (fr) | 2016-11-23 | 2018-12-07 | Universite de Bordeaux | Microcompartiment cellulaire et procedes de preparation |
| CN110452869A (zh) * | 2016-11-26 | 2019-11-15 | 中国科学院大连化学物理研究所 | 一种高通量形成拟胚体的微阵列芯片的制备方法与应用 |
| WO2019104036A1 (en) * | 2017-11-21 | 2019-05-31 | Georgetown University | Process for continuous cell culture of gpscs |
| WO2020080561A1 (ko) * | 2018-10-15 | 2020-04-23 | (주)메디톡스 | 만능성 줄기세포 배양용 배지 및 그를 이용한 배양 방법 |
| AU2019368313A1 (en) * | 2018-10-24 | 2021-05-20 | Hebecell Corporation | Methods and systems for manufacturing hematopoietic lineage cells |
| KR102120378B1 (ko) * | 2019-07-04 | 2020-06-08 | 연세대학교 산학협력단 | 암 오가노이드의 제조 방법 및 이의 용도 |
| CN114929856A (zh) * | 2019-10-30 | 2022-08-19 | 总医院公司 | Ipsc衍生的肺泡细胞的高通量培养 |
| KR102543215B1 (ko) * | 2020-02-10 | 2023-06-14 | 연세대학교 산학협력단 | 모낭조직 배양액을 포함하는 탈모의 예방 또는 치료용 조성물 |
| KR102458606B1 (ko) * | 2020-03-06 | 2022-10-25 | 경희대학교 산학협력단 | 마이크로캐리어 기반 4차원 세포 배양기 및 이를 이용한 세포배양 모니터링 방법 |
| JP7722712B2 (ja) * | 2020-03-24 | 2025-08-13 | 学校法人自治医科大学 | 一時処理培地、処理キット、胚発生停止抑制剤、胚発生停止抑制方法、発生工学産物作製方法、移植方法、及び治療方法 |
| CA3181611A1 (en) * | 2020-06-11 | 2021-12-16 | Paul Simmons | 3d culture of mesenchymal lineage precursor or stem cells |
| CN114763534B (zh) * | 2021-01-13 | 2024-04-26 | 合肥中科普瑞昇生物医药科技有限公司 | 原代胃肠间质瘤细胞培养基、培养方法及其应用 |
| CN112843338B (zh) * | 2021-02-08 | 2022-05-20 | 康膝生物医疗(深圳)有限公司 | 一种制备含胶原蛋白的间充质干细胞注射剂的方法 |
| CN113201488A (zh) * | 2021-05-13 | 2021-08-03 | 圣美基因科技(北京)有限公司 | 一种间充质干细胞大规模培养方法 |
| CN113388582A (zh) * | 2021-06-21 | 2021-09-14 | 香港再生医学有限公司 | 促使iPSC分化为外周神经干细胞的方法及培养基和系统 |
| TWI861626B (zh) * | 2021-12-21 | 2024-11-11 | 國璽幹細胞應用技術股份有限公司 | 穩定擴增富潛能幹細胞的方法 |
| WO2023123299A1 (en) * | 2021-12-31 | 2023-07-06 | Beijing Theraxyte Bioscience Co., Ltd. | Compositions and methods for culturing stem cells |
| CN115747197B (zh) * | 2023-01-06 | 2023-04-21 | 中国肉类食品综合研究中心 | 可食用3d打印生物墨水及制备方法和在培育肉中的应用 |
Citations (2)
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| WO2008089351A1 (en) * | 2007-01-17 | 2008-07-24 | Wisconsin Alumni Research Foundation | Improved culture of stem cells |
| WO2009006422A1 (en) * | 2007-06-29 | 2009-01-08 | Stem Cell Products, Inc. | Automated method and apparatus for embryonic stem cell culture |
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| US5776747A (en) | 1994-07-20 | 1998-07-07 | Cytotherapeutics, Inc. | Method for controlling the distribution of cells within a bioartificial organ using polycthylene oxide-poly (dimethylsiloxane) copolymer |
| DK1007631T4 (da) | 1997-07-14 | 2009-04-27 | Osiris Therapeutics Inc | Hjertemuskelregeneration ved anvendelse af mesenkymale stamceller |
| EP1448053A4 (en) | 2001-10-02 | 2005-03-09 | Becton Dickinson Co | PROLIFERATION AND DIFFERENTIATION OF STEM CELLS BY EXTRACELLULAR MATRIX AND OTHER MOLECULES |
| US20060205071A1 (en) | 2003-07-17 | 2006-09-14 | Gamida-Cell Ltd. | Methods for ex-vivo expanding stem/progenitor cells |
| US20080026460A1 (en) | 2006-06-20 | 2008-01-31 | Palecek Sean P | Method for culturing stem cells |
| WO2005065354A2 (en) | 2003-12-31 | 2005-07-21 | The Burnham Institute | Defined media for pluripotent stem cell culture |
| DE102004043256B4 (de) | 2004-09-07 | 2013-09-19 | Rheinische Friedrich-Wilhelms-Universität Bonn | Skalierbarer Prozess zur Kultivierung undifferenzierter Stammzellen in Suspension |
| US20060198827A1 (en) * | 2005-02-04 | 2006-09-07 | Shulamit Levenberg | Engineering vascularized muscle tissue |
| WO2006091921A2 (en) | 2005-02-25 | 2006-08-31 | Drexel University | Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications |
| WO2007030469A2 (en) | 2005-09-06 | 2007-03-15 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Transplantable cell growth niche and related compositions and methods |
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| GB2447191B (en) | 2005-12-22 | 2011-08-03 | Es Cell Int Pte Ltd | Direct differentiation of cardiomyocytes from human embryonic stem cells |
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| US8691569B2 (en) | 2008-03-17 | 2014-04-08 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| US20110070648A1 (en) | 2008-05-15 | 2011-03-24 | Ge Healthcare Bio-Sciences Ab | Method for cell expansion |
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-
2010
- 2010-03-12 WO PCT/SG2010/000091 patent/WO2010107392A1/en not_active Ceased
- 2010-03-12 US US13/257,674 patent/US9150829B2/en active Active
- 2010-03-12 KR KR1020117024726A patent/KR20110137805A/ko not_active Withdrawn
- 2010-03-12 SG SG2011067725A patent/SG174471A1/en unknown
- 2010-03-12 EP EP10753781.3A patent/EP2408903B1/en active Active
- 2010-03-12 JP JP2012500748A patent/JP2012520672A/ja active Pending
- 2010-03-12 CN CN2010800219292A patent/CN102428172A/zh active Pending
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| WO2008089351A1 (en) * | 2007-01-17 | 2008-07-24 | Wisconsin Alumni Research Foundation | Improved culture of stem cells |
| WO2009006422A1 (en) * | 2007-06-29 | 2009-01-08 | Stem Cell Products, Inc. | Automated method and apparatus for embryonic stem cell culture |
Non-Patent Citations (2)
| Title |
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| JPN6014031554; David A. Classen, et al: Molecular Reproduction and Development Vol.76, 20090220, p.722-732 * |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019022496A (ja) * | 2012-11-08 | 2019-02-14 | バイアサイト インク | 幹細胞集合体懸濁液組成物、その分化方法 |
| JP2021007393A (ja) * | 2012-11-08 | 2021-01-28 | バイアサイト インク | 幹細胞集合体懸濁液組成物、その分化方法 |
| JP2023075135A (ja) * | 2012-11-08 | 2023-05-30 | バイアサイト インク | 霊長類多能性幹細胞集合体懸濁培養物及びその分化方法 |
| JP7580508B2 (ja) | 2012-11-08 | 2024-11-11 | ヴィアサイト,インコーポレイテッド | 霊長類多能性幹細胞集合体懸濁培養物及びその分化方法 |
| KR101845588B1 (ko) * | 2014-04-07 | 2018-04-05 | 한양대학교 산학협력단 | 적혈구계 세포의 인 비트로 확장 |
| US10273455B2 (en) | 2014-04-07 | 2019-04-30 | Iucf-Hyu | In vitro expansion of erythroid cells |
| WO2016136986A1 (ja) * | 2015-02-27 | 2016-09-01 | ロート製薬株式会社 | 間葉系幹細胞培養用培地、間葉系幹細胞の培養方法及び間葉系幹細胞 |
| JPWO2016136986A1 (ja) * | 2015-02-27 | 2017-12-07 | ロート製薬株式会社 | 間葉系幹細胞培養用培地、間葉系幹細胞の培養方法及び間葉系幹細胞 |
| WO2017170849A1 (ja) * | 2016-03-30 | 2017-10-05 | 国立研究開発法人医薬基盤・健康・栄養研究所 | ナイーブ型多能性幹細胞培養用培地および多能性幹細胞の培養方法 |
| JPWO2017170849A1 (ja) * | 2016-03-30 | 2019-05-16 | 協和発酵バイオ株式会社 | ナイーブ型多能性幹細胞培養用培地および多能性幹細胞の培養方法 |
| JP2023537969A (ja) * | 2020-08-10 | 2023-09-06 | リネージ セル セラピューティクス インコーポレイテッド | 胚性幹細胞増殖のための組成物及び方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2408903B1 (en) | 2014-08-06 |
| WO2010107392A1 (en) | 2010-09-23 |
| US9150829B2 (en) | 2015-10-06 |
| SG174471A1 (en) | 2011-10-28 |
| US20120009645A1 (en) | 2012-01-12 |
| EP2408903A1 (en) | 2012-01-25 |
| KR20110137805A (ko) | 2011-12-23 |
| EP2408903A4 (en) | 2013-02-20 |
| CN102428172A (zh) | 2012-04-25 |
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