JP2012519653A5 - - Google Patents

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Publication number
JP2012519653A5
JP2012519653A5 JP2011537754A JP2011537754A JP2012519653A5 JP 2012519653 A5 JP2012519653 A5 JP 2012519653A5 JP 2011537754 A JP2011537754 A JP 2011537754A JP 2011537754 A JP2011537754 A JP 2011537754A JP 2012519653 A5 JP2012519653 A5 JP 2012519653A5
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JP
Japan
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group
optionally substituted
substituent
substituted
alkyl
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JP2011537754A
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English (en)
Japanese (ja)
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JP5645839B2 (ja
JP2012519653A (ja
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Priority claimed from PCT/JP2010/054073 external-priority patent/WO2010101302A1/en
Publication of JP2012519653A publication Critical patent/JP2012519653A/ja
Publication of JP2012519653A5 publication Critical patent/JP2012519653A5/ja
Application granted granted Critical
Publication of JP5645839B2 publication Critical patent/JP5645839B2/ja
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JP2011537754A 2009-03-05 2010-03-04 Ｃｄｃ７キナーゼ阻害剤としてのチエノピリミジン Active JP5645839B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US15776009P 2009-03-05 2009-03-05
US61/157,760 2009-03-05
US29499110P 2010-01-14 2010-01-14
US61/294,991 2010-01-14
US29833810P 2010-01-26 2010-01-26
US61/298,338 2010-01-26
PCT/JP2010/054073 WO2010101302A1 (en) 2009-03-05 2010-03-04 Thienopyrimidine as cdc7 kinase inhibitors

Publications (3)

Publication Number Publication Date
JP2012519653A JP2012519653A (ja) 2012-08-30
JP2012519653A5 true JP2012519653A5 (https=) 2013-03-07
JP5645839B2 JP5645839B2 (ja) 2014-12-24

Family

ID=42112336

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011537754A Active JP5645839B2 (ja) 2009-03-05 2010-03-04 Ｃｄｃ７キナーゼ阻害剤としてのチエノピリミジン

Country Status (4)

Country Link
US (1) US8691828B2 (https=)
EP (1) EP2403857B1 (https=)
JP (1) JP5645839B2 (https=)
WO (1) WO2010101302A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG183304A1 (en) 2010-02-17 2012-09-27 Takeda Pharmaceutical Heterocyclic compound
BR112014015720B1 (pt) 2011-12-30 2020-03-17 Hanmi Pharm. Co., Ltd. Derivados de tieno[3,2-d]pirimidina, composição farmacêutica e uso dos mesmos para a prevenção ou tratamento de uma doença causada por ativação anormal de uma proteína quinase
JP6569908B2 (ja) 2014-01-31 2019-09-04 カルナバイオサイエンス株式会社 抗がん剤組成物
WO2018217439A1 (en) * 2017-05-21 2018-11-29 Zhang Hai Jun Substituted [5,6]cyclic-4(3h)-pyrimidinones as anticancer agents
GB201807147D0 (en) 2018-05-01 2018-06-13 Oncologica Uk Ltd Therapeutic combination
NL2021185B1 (en) 2018-06-26 2020-01-06 Stichting Het Nederlands Kanker Inst Antoni Van Leeuwenhoek Ziekenhuis Combination Therapy and Use Thereof for Treating Cancer
AU2019350581B2 (en) 2018-09-24 2025-07-10 Carna Biosciences, Inc. Methods of treatment of cancer comprising Cdc7 inhibitors
US20230101747A1 (en) * 2019-12-06 2023-03-30 Schrödinger, Inc. Cyclic compounds and methods of using same
CN117120447A (zh) * 2021-03-18 2023-11-24 薛定谔公司 环状化合物和其使用方法
TW202300150A (zh) * 2021-03-18 2023-01-01 美商薛定諤公司 環狀化合物及其使用方法
CN115260211B (zh) * 2021-04-29 2024-02-06 长春金赛药业有限责任公司 含噻吩稠环类衍生物、药物组合物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1396488A1 (en) * 2001-05-23 2004-03-10 Mitsubishi Pharma Corporation Fused heterocyclic compound and medicinal use thereof
SI1631295T1 (sl) * 2003-06-06 2010-06-30 Arexis Ab Uporaba kondenziranih heterocikličnih spojin kotSCCE inhibitorjev za zdravljenje kožnih bolezni
JP2007501827A (ja) 2003-08-08 2007-02-01 ファルマシア・イタリア・エス・ピー・エー キナーゼ阻害剤として活性なピリミジルピロール誘導体
US7279575B2 (en) 2003-08-08 2007-10-09 Pfizer Italia S.R.L. Pyrimidylpyrrole derivatives active as kinase inhibitors
WO2005095386A1 (en) 2004-03-30 2005-10-13 Chiron Corporation Substituted thiophene derivatives as anti-cancer agents
JP2009501217A (ja) * 2005-07-15 2009-01-15 アストラゼネカ アクチボラグ 治療薬
US20070142414A1 (en) * 2005-12-16 2007-06-21 Pharmacia Italia S.P.A. N-substituted pyrrolopyridinones active as kinase inhibitors
US8299080B2 (en) * 2006-12-13 2012-10-30 Aska Pharmaceutical Co., Ltd. Substituted imidazo[1,5-A] quinoxalines as a PDE9 inhibitor
WO2008072778A1 (ja) * 2006-12-13 2008-06-19 Aska Pharmaceutical Co., Ltd. 尿路系疾患の処置剤

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