JP2012519556A5 - - Google Patents

Download PDF

Info

Publication number
JP2012519556A5
JP2012519556A5 JP2011553160A JP2011553160A JP2012519556A5 JP 2012519556 A5 JP2012519556 A5 JP 2012519556A5 JP 2011553160 A JP2011553160 A JP 2011553160A JP 2011553160 A JP2011553160 A JP 2011553160A JP 2012519556 A5 JP2012519556 A5 JP 2012519556A5
Authority
JP
Japan
Prior art keywords
cartilage
composition according
bone
phase
pdgf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011553160A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012519556A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/026450 external-priority patent/WO2010102266A1/en
Publication of JP2012519556A publication Critical patent/JP2012519556A/ja
Publication of JP2012519556A5 publication Critical patent/JP2012519556A5/ja
Pending legal-status Critical Current

Links

JP2011553160A 2009-03-05 2010-03-05 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法 Pending JP2012519556A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20952009P 2009-03-05 2009-03-05
US61/209,520 2009-03-05
US16425909P 2009-03-27 2009-03-27
US61/164,259 2009-03-27
PCT/US2010/026450 WO2010102266A1 (en) 2009-03-05 2010-03-05 Platelet-derived growth factor compositions and methods for the treatment of osteochondral defects

Publications (2)

Publication Number Publication Date
JP2012519556A JP2012519556A (ja) 2012-08-30
JP2012519556A5 true JP2012519556A5 (enExample) 2013-04-11

Family

ID=42710033

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011553160A Pending JP2012519556A (ja) 2009-03-05 2010-03-05 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法

Country Status (8)

Country Link
US (2) US20100247651A1 (enExample)
EP (1) EP2403514A4 (enExample)
JP (1) JP2012519556A (enExample)
KR (1) KR20110135949A (enExample)
AU (1) AU2010221089A1 (enExample)
CA (1) CA2754501A1 (enExample)
IL (1) IL214937A0 (enExample)
WO (1) WO2010102266A1 (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
WO2007061889A2 (en) 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
ES2427993T3 (es) 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
WO2008005427A2 (en) 2006-06-30 2008-01-10 Biomimetic Therapeutics, Inc. Pdgf-biomatrix compositions and methods for treating rotator cuff injuries
EP2462895B1 (en) 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
WO2008103690A2 (en) * 2007-02-20 2008-08-28 Biomimetic Therapeutics, Inc. Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using pdgf and a bone matrix
CA2715254A1 (en) 2008-02-07 2009-08-13 Biomimetic Therapeutics, Inc. Compositions and methods for distraction osteogenesis
AU2009288118B2 (en) 2008-09-02 2014-12-11 Allergan, Inc. Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
US9192695B2 (en) 2008-11-20 2015-11-24 Allosource Allografts combined with tissue derived stem cells for bone healing
US20100249924A1 (en) * 2009-03-27 2010-09-30 Allergan, Inc. Bioerodible matrix for tissue involvement
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
DK2550027T4 (da) 2010-03-22 2019-05-13 Allergan Inc Tværbundne polysaccharid- og protein-polysaccharid-hydrogeler til blødvævsforøgelse
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US20120142628A1 (en) * 2010-12-07 2012-06-07 Allergan, Inc. Methods for treating crepitus
WO2012082773A1 (en) * 2010-12-13 2012-06-21 Biomimetic Therapeutics, Inc. Compositions and methods for spine fusion procedures
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
ES2738208T3 (es) 2011-06-03 2020-01-20 Allergan Ind Sas Composiciones de relleno dérmico que incluyen antioxidantes
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9017417B2 (en) 2012-05-30 2015-04-28 Kensey Nash Bvf Technology Llc Subchondral bone repair system
AU2013342257B2 (en) 2012-11-08 2018-08-30 Smith & Nephew, Inc. Improved reattachment of detached cartilage to subchondral bone
WO2014074804A2 (en) * 2012-11-08 2014-05-15 Smith & Nephew, Inc. Methods and compositions suitable for improved reattachment of detached cartilage to subchondral bone
US9186380B2 (en) 2012-11-15 2015-11-17 Allosource Minced cartilage systems and methods
US9186253B2 (en) 2013-02-22 2015-11-17 Allosource Cartilage mosaic compositions and methods
KR102312720B1 (ko) 2013-03-15 2021-10-13 알로소스 연조직 회복 및 재생을 위한 세포 재배치된 콜라겐 매트릭스
AU2014236705B2 (en) 2013-03-15 2018-04-12 Allosource Perforated osteochondral allograft compositions
US10086112B2 (en) * 2014-02-20 2018-10-02 Merck Patent Gmbh Implant comprising FGF-18
ES2761558T3 (es) 2014-09-30 2020-05-20 Allergan Ind Sas Composiciones de hidrogel estables que incluyen aditivos
MX2017004520A (es) 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.
PL3256179T3 (pl) 2015-02-13 2020-05-18 Allergan Industrie, Sas Implanty do kształtowania, uwydatniania lub korygowania cech twarzy takich jak broda
GB201513097D0 (en) * 2015-07-24 2015-09-09 Univ Sheffield Medical implant
US10966816B1 (en) 2019-10-18 2021-04-06 Sparta Biopharma LLC Connective tissue to bone interface scaffolds
US11364324B2 (en) 2020-08-24 2022-06-21 Sparta Biopharma Inc. Methods of forming bone interface scaffolds
CN116195741B (zh) * 2021-11-30 2024-07-09 内蒙古伊利实业集团股份有限公司 乳双歧杆菌bb-12在保护软骨中的应用

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3943072A (en) * 1971-12-15 1976-03-09 United Kingdom Atomic Energy Authority Separation of molecules
USRE33161E (en) * 1982-04-29 1990-02-06 American Dental Association Health Foundation Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements
US5187263A (en) * 1984-10-12 1993-02-16 Zymogenetics, Inc. Expression of biologically active PDGE analogs in eucaryotic cells
US5629191A (en) * 1985-01-03 1997-05-13 Integra Lifesciences Corporation Method of making a porous matrix particle
US5516896A (en) * 1985-02-25 1996-05-14 Zymogenetics, Inc. Biologically active B-chain homodimers
CA1260391A (en) * 1985-03-28 1989-09-26 Karl A. Piez Xenogeneic collagen/mineral preparations in bone repair
US5187076A (en) * 1986-07-01 1993-02-16 Genetics Institute, Inc. DNA sequences encoding BMP-6 proteins
US5013649A (en) * 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
US5106748A (en) * 1986-07-01 1992-04-21 Genetics Institute, Inc. Dna sequences encoding 5 proteins
US5108922A (en) * 1986-07-01 1992-04-28 Genetics Institute, Inc. DNA sequences encoding BMP-1 products
US5019559A (en) * 1986-11-14 1991-05-28 President And Fellows Of Harvard College Wound healing using PDGF and IGF-II
US5124316A (en) * 1986-11-14 1992-06-23 President And Fellows Of Harvard College Method for periodontal regeneration
US5219759A (en) * 1987-04-22 1993-06-15 Chiron Corporation Recombinant DNA encoding PDGF A-chain polypeptide and expression vectors
US5759815A (en) * 1988-02-11 1998-06-02 Creative Biomolecules, Inc. Production of platelet derived growth factor (PDGF) an muteins thereof
US4904259A (en) * 1988-04-29 1990-02-27 Samuel Itay Compositions and methods for repair of cartilage and bone
US5219576A (en) * 1988-06-30 1993-06-15 Collagen Corporation Collagen wound healing matrices and process for their production
US5599558A (en) * 1989-09-15 1997-02-04 Curative Technologies, Inc. Selecting amounts of platelet releasate for efficacious treatment of tissue
US5112354A (en) * 1989-11-16 1992-05-12 Northwestern University Bone allograft material and method
US5011910A (en) * 1989-12-28 1991-04-30 Washington University Reagent and method for determining activity of retroviral protease
TW199858B (enExample) * 1990-03-30 1993-02-11 Fujirebio Kk
US5518680A (en) * 1993-10-18 1996-05-21 Massachusetts Institute Of Technology Tissue regeneration matrices by solid free form fabrication techniques
US7963997B2 (en) * 2002-07-19 2011-06-21 Kensey Nash Corporation Device for regeneration of articular cartilage and other tissue
US6180606B1 (en) * 1994-09-28 2001-01-30 Gensci Orthobiologics, Inc. Compositions with enhanced osteogenic potential, methods for making the same and uses thereof
US5614206A (en) * 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
US5635372A (en) * 1995-05-18 1997-06-03 Genetics Institute, Inc. BMP-15 compositions
US5676976A (en) * 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US6541037B1 (en) * 1995-05-19 2003-04-01 Etex Corporation Delivery vehicle
US6027742A (en) * 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
DK1486565T3 (da) * 1995-10-11 2008-03-10 Novartis Vaccines & Diagnostic Kombination af PDGF, KGF, IGF og IGFBP til sårheling
US5747273A (en) * 1996-05-07 1998-05-05 Diagnostic Systems Laboratories, Inc. Immunoassay of total insulin-like growth factor binding protein-1
CA2252860C (en) * 1996-05-28 2011-03-22 1218122 Ontario Inc. Resorbable implant biomaterial made of condensed calcium phosphate particles
FR2749756B1 (fr) * 1996-06-14 1998-09-11 Bioland Procede de preparation d'un materiau composite implantable, materiau obtenu, implant comprenant ce materiau et kit de mise en oeuvre
US6037519A (en) * 1997-10-20 2000-03-14 Sdgi Holdings, Inc. Ceramic fusion implants and compositions
US5866165A (en) * 1997-01-15 1999-02-02 Orquest, Inc. Collagen-polysaccharide matrix for bone and cartilage repair
US7041641B2 (en) * 1997-03-20 2006-05-09 Stryker Corporation Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
JP3334558B2 (ja) * 1997-04-23 2002-10-15 富士レビオ株式会社 酵素免疫測定方法及び試験片
US20020018796A1 (en) * 1998-01-28 2002-02-14 John F. Wironen Thermally sterilized bone paste
US20030114936A1 (en) * 1998-10-12 2003-06-19 Therics, Inc. Complex three-dimensional composite scaffold resistant to delimination
US6224635B1 (en) * 1998-11-06 2001-05-01 Hospital For Joint Diseases Implantation of surgical implants with calcium sulfate
US6663870B2 (en) * 1998-12-07 2003-12-16 Zymogenetics, Inc. Methods for promoting growth of bone using zvegf3
ATE253385T1 (de) * 1999-02-04 2003-11-15 Sdgi Holdings Inc Hochmineralisierte osteogene schwammzusammensetzungen und ihre verwendung
US6296602B1 (en) * 1999-03-17 2001-10-02 Transfusion Technologies Corporation Method for collecting platelets and other blood components from whole blood
CA2370063C (en) * 1999-03-19 2012-10-02 The Regents Of The University Of Michigan Mineralization and cellular patterning on biomaterial surfaces
WO2000061256A1 (en) * 1999-04-12 2000-10-19 Harvest Technologies Corporation Method and apparatus for producing platelet rich plasma and/or platelet concentrate
SE515227C2 (sv) * 1999-04-28 2001-07-02 Bruce Medical Ab Kropp för åstadkommande av in- och tillväxt av benvävnad och/ eller bindväv och sätt för framställning av kroppen
US6468543B1 (en) * 1999-05-03 2002-10-22 Zymogenetics, Inc. Methods for promoting growth of bone using ZVEGF4
US6710025B1 (en) * 1999-05-26 2004-03-23 The Brigham And Women's Hospital, Inc. Treatment of damaged tissue using agents that modulate the activity of alpha-smooth muscle actin
DE19940717A1 (de) * 1999-08-26 2001-03-01 Gerontocare Gmbh Resorblerbares Knochenersatz- und Knochenaufbaumaterial
CA2328818A1 (en) * 1999-12-16 2001-06-16 Isotis B.V. Porous ceramic body
IT1316769B1 (it) * 2000-02-18 2003-05-12 Getters Spa Pannello evacuato per isolamento termico con ridotta conduzione dicalore ai bordi
US7022506B2 (en) * 2000-02-23 2006-04-04 The Trustees Of The University Of Pennsylvania Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee
US20030055511A1 (en) * 2000-03-03 2003-03-20 Schryver Jeffrey E. Shaped particle comprised of bone material and method of making the particle
US20020006437A1 (en) * 2000-05-01 2002-01-17 Grooms Jamie M. Non-migration tissue capsule
EP1287506A2 (en) * 2000-05-19 2003-03-05 Europrint Holdings Limited Method and system for implementing a game
US20020022885A1 (en) * 2000-05-19 2002-02-21 Takahiro Ochi Biomaterial
DK1294414T3 (da) * 2000-06-29 2006-07-24 Biosyntech Canada Inc Præparat og fremgangsmåde til heling og regenerering af brusk og andre væv
DK177997B1 (da) * 2000-07-19 2015-02-23 Ed Geistlich Söhne Ag Für Chemische Ind Knoglemateriale og collagenkombination til opheling af beskadigede led
US6739112B1 (en) * 2000-08-21 2004-05-25 Nu Vasive, Inc. Bone allograft packaging system
US6773723B1 (en) * 2000-08-30 2004-08-10 Depuy Acromed, Inc. Collagen/polysaccharide bilayer matrix
CA2365376C (en) * 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US7192604B2 (en) * 2000-12-22 2007-03-20 Ethicon, Inc. Implantable biodegradable devices for musculoskeletal repair or regeneration
US7005135B2 (en) * 2001-01-30 2006-02-28 Ethicon Inc. Glass scaffolds with controlled resorption rates and methods for making same
US6743232B2 (en) * 2001-02-26 2004-06-01 David W. Overaker Tissue scaffold anchor for cartilage repair
US6949251B2 (en) * 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue
US20030049328A1 (en) * 2001-03-02 2003-03-13 Dalal Paresh S. Porous beta-tricalcium phosphate granules and methods for producing same
US20030109537A1 (en) * 2001-07-09 2003-06-12 Turner Russell T. Methods and materials for treating bone conditions
ATE384783T1 (de) * 2001-10-19 2008-02-15 Zymogenetics Inc Dimerisierter wachstumsfaktor sowie materialien und verfahren zu seiner herstellung
WO2003055418A1 (en) * 2001-12-21 2003-07-10 Lagow Richard J Calcium phosphate bone replacement materials and methods of use thereof
US7879107B2 (en) * 2002-02-20 2011-02-01 The Cleveland Clinic Foundation Composition and method for inducing bone growth and healing
JP3739715B2 (ja) * 2002-03-19 2006-01-25 オリンパス株式会社 人工骨および組織工学用担体
WO2003089022A1 (en) * 2002-04-18 2003-10-30 University Of Florida Biomimetic organic/inorganic composites, processes for their production, and methods of use
EP1539185A4 (en) * 2002-05-02 2006-04-05 Osteoscreen Inc METHODS AND COMPOSITIONS FOR STIMULATING BONE GROWTH USING NITRIC OXIDE FREEZING BISPHOSPHONATE CONJUGATES
WO2003094617A2 (en) * 2002-05-06 2003-11-20 Genentech, Inc. Use of vegf for treating bone defects
JP2003038635A (ja) * 2002-06-10 2003-02-12 Olympus Optical Co Ltd 骨軟骨移植材
US20040002770A1 (en) * 2002-06-28 2004-01-01 King Richard S. Polymer-bioceramic composite for orthopaedic applications and method of manufacture thereof
DE60300666T2 (de) * 2002-07-11 2006-04-27 Biomet Deutschland Gmbh Verfahren zur Herstellung poröser Calciumphosphatstückchen und -granulaten aus der Gelatineverarbeitung
US7744651B2 (en) * 2002-09-18 2010-06-29 Warsaw Orthopedic, Inc Compositions and methods for treating intervertebral discs with collagen-based materials
US20040078090A1 (en) * 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
US7824701B2 (en) * 2002-10-18 2010-11-02 Ethicon, Inc. Biocompatible scaffold for ligament or tendon repair
US7217294B2 (en) * 2003-08-20 2007-05-15 Histogenics Corp. Acellular matrix implants for treatment of articular cartilage, bone or osteochondral defects and injuries and method for use thereof
CU23352A1 (es) * 2003-10-16 2009-03-16 Centro Nacional De Investigaciones Cientificas Biomateriales compuestos para implantes óseos
GB2407580B (en) * 2003-10-28 2009-02-25 Univ Cambridge Tech Biomaterial
US20050098915A1 (en) * 2003-11-07 2005-05-12 Smith & Nephew Inc. Manufacture of bone graft substitutes
US20080220044A1 (en) * 2007-03-06 2008-09-11 Semler Eric J Cancellous construct with support ring for repair of osteochondral defects
US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
ITMI20050343A1 (it) * 2005-03-04 2006-09-05 Fin Ceramica Faenza S R L Sostituto cartilagineo e osteocindrale comprendente una struttura multistrato e relativo impiego
WO2007061889A2 (en) * 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
WO2008005427A2 (en) * 2006-06-30 2008-01-10 Biomimetic Therapeutics, Inc. Pdgf-biomatrix compositions and methods for treating rotator cuff injuries
EP2462895B1 (en) * 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
AU2008265850B2 (en) * 2007-06-15 2014-06-26 Warsaw Orthopedic, Inc. Bone matrix compositions and methods
CN104623669A (zh) * 2007-08-22 2015-05-20 斯丹姆涅恩有限公司 含细胞因子溶液的新组合物
US7993679B2 (en) * 2007-09-25 2011-08-09 Integra Lifesciences Corporation Flowable wound matrix and its preparation and use

Similar Documents

Publication Publication Date Title
JP2012519556A5 (enExample)
Le et al. The components of bone and what they can teach us about regeneration
WO2010102266A8 (en) Platelet-derived growth factor compositions and methods for the treatment of osteochondral defects
ES2608777T3 (es) Armazón recubierto con hidrogel
Dorozhkin Calcium orthophosphates as bioceramics: state of the art
JP5295121B2 (ja) 関節内軟骨および骨組織修復のためのinsituシステム
JP2009515668A5 (enExample)
DE602006010341D1 (de) Knorpelartiges und osteochondrales substitut aus eg
JP2008516675A5 (enExample)
NZ602861A (en) Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
EP2051658A4 (en) COMPOUND IMPLANTS FOR PROMOTING BONE REGENERATION AND REINFORCEMENT AND METHOD FOR THEIR PRODUCTION AND USE
JP2013509261A5 (enExample)
JP2014196354A5 (enExample)
WO2012134059A3 (ko) 골-연골 재생용 복합 지지체, 이의 제조 방법 및 이를 유효성분으로 함유하는 골-연골 질환 치료용 조성물
HK1209177A1 (en) Tissue repair devices and scaffolds
WO2011156586A3 (en) Multilayered silk scaffolds for meniscus tissue engineering
WO2009142770A3 (en) Compositions and methods for generating musculoskeletal tissue
Jungbluth et al. Platelet‐rich plasma on calcium phosphate granules promotes metaphyseal bone healing in mini‐pigs
JP2011511808A5 (enExample)
Hirota et al. Combination with allogenic bone reduces early absorption of β-tricalcium phosphate (β-TCP) and enhances the role as a bone regeneration scaffold. Experimental animal study in rat mandibular bone defects
Li et al. Repair of rabbit radial bone defects using true bone ceramics combined with BMP-2-related peptide and type I collagen
WO2010115138A3 (en) Devices and injectable or implantable compositions for intervertebral fusion
Vajrabhaya et al. Cytotoxic and the proliferative effect of cuttlefish bone on MC3T3-E1 osteoblast cell line
Meimandi-Parizi et al. Healing potential of nanohydroxyapatite, gelatin, and fibrin-platelet glue combination as tissue engineered scaffolds in radial bone defects of rats
WO2007054939A3 (en) Method for non-autologous cartilage regeneration