JP2012515780A5 - - Google Patents
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- Publication number
- JP2012515780A5 JP2012515780A5 JP2011548085A JP2011548085A JP2012515780A5 JP 2012515780 A5 JP2012515780 A5 JP 2012515780A5 JP 2011548085 A JP2011548085 A JP 2011548085A JP 2011548085 A JP2011548085 A JP 2011548085A JP 2012515780 A5 JP2012515780 A5 JP 2012515780A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- oral care
- silica particles
- tooth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 46
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 16
- 239000002245 particle Substances 0.000 claims 12
- 239000003795 chemical substances by application Substances 0.000 claims 11
- 238000000034 method Methods 0.000 claims 11
- 239000000853 adhesive Substances 0.000 claims 6
- 230000001070 adhesive effect Effects 0.000 claims 6
- 239000000551 dentifrice Substances 0.000 claims 5
- -1 fluoride compound Chemical class 0.000 claims 5
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 4
- INVGWHRKADIJHF-UHFFFAOYSA-N Sanguinarin Chemical compound C1=C2OCOC2=CC2=C3[N+](C)=CC4=C(OCO5)C5=CC=C4C3=CC=C21 INVGWHRKADIJHF-UHFFFAOYSA-N 0.000 claims 4
- 239000002253 acid Substances 0.000 claims 4
- 229960001927 cetylpyridinium chloride Drugs 0.000 claims 4
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 claims 4
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 229910052700 potassium Inorganic materials 0.000 claims 4
- 239000011591 potassium Substances 0.000 claims 4
- 210000005239 tubule Anatomy 0.000 claims 4
- ANAAMBRRWOGKGU-UHFFFAOYSA-M 4-ethyl-1-tetradecylpyridin-1-ium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC[N+]1=CC=C(CC)C=C1 ANAAMBRRWOGKGU-UHFFFAOYSA-M 0.000 claims 3
- 229940090898 Desensitizer Drugs 0.000 claims 3
- 210000004268 dentin Anatomy 0.000 claims 3
- 201000002170 dentin sensitivity Diseases 0.000 claims 3
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 230000036347 tooth sensitivity Effects 0.000 claims 3
- WCGUUGGRBIKTOS-GPOJBZKASA-N (3beta)-3-hydroxyurs-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C WCGUUGGRBIKTOS-GPOJBZKASA-N 0.000 claims 2
- DTOUUUZOYKYHEP-UHFFFAOYSA-N 1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine Chemical compound CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1 DTOUUUZOYKYHEP-UHFFFAOYSA-N 0.000 claims 2
- YFVBASFBIJFBAI-UHFFFAOYSA-M 1-tetradecylpyridin-1-ium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC[N+]1=CC=CC=C1 YFVBASFBIJFBAI-UHFFFAOYSA-M 0.000 claims 2
- RWMSXNCJNSILON-UHFFFAOYSA-N 2-[4-(2-propylpentyl)piperidin-1-yl]ethanol Chemical compound CCCC(CCC)CC1CCN(CCO)CC1 RWMSXNCJNSILON-UHFFFAOYSA-N 0.000 claims 2
- PGKQTZHDCHKDQK-UHFFFAOYSA-N 2-phenylethenylphosphonic acid Chemical compound OP(O)(=O)C=CC1=CC=CC=C1 PGKQTZHDCHKDQK-UHFFFAOYSA-N 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims 2
- 241000209507 Camellia Species 0.000 claims 2
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims 2
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- FCEXWTOTHXCQCQ-UHFFFAOYSA-N Ethoxydihydrosanguinarine Natural products C12=CC=C3OCOC3=C2C(OCC)N(C)C(C2=C3)=C1C=CC2=CC1=C3OCO1 FCEXWTOTHXCQCQ-UHFFFAOYSA-N 0.000 claims 2
- BYTORXDZJWWIKR-UHFFFAOYSA-N Hinokiol Natural products CC(C)c1cc2CCC3C(C)(CO)C(O)CCC3(C)c2cc1O BYTORXDZJWWIKR-UHFFFAOYSA-N 0.000 claims 2
- 240000000950 Hippophae rhamnoides Species 0.000 claims 2
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 108010053775 Nisin Proteins 0.000 claims 2
- NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 claims 2
- SRIJLARXVRHZKD-UHFFFAOYSA-N OP(O)=O.C=CC1=CC=CC=C1 Chemical compound OP(O)=O.C=CC1=CC=CC=C1 SRIJLARXVRHZKD-UHFFFAOYSA-N 0.000 claims 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 2
- 241000241413 Propolis Species 0.000 claims 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 2
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims 2
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 claims 2
- LFVVNPBBFUSSHL-UHFFFAOYSA-N alexidine Chemical compound CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC LFVVNPBBFUSSHL-UHFFFAOYSA-N 0.000 claims 2
- 229950010221 alexidine Drugs 0.000 claims 2
- 125000000129 anionic group Chemical group 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 2
- 229960000686 benzalkonium chloride Drugs 0.000 claims 2
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims 2
- 229960003260 chlorhexidine Drugs 0.000 claims 2
- 235000018597 common camellia Nutrition 0.000 claims 2
- 229910001431 copper ion Inorganic materials 0.000 claims 2
- 229960003624 creatine Drugs 0.000 claims 2
- 239000006046 creatine Substances 0.000 claims 2
- 230000001186 cumulative effect Effects 0.000 claims 2
- QSFOWAYMMZCQNF-UHFFFAOYSA-N delmopinol Chemical compound CCCC(CCC)CCCC1COCCN1CCO QSFOWAYMMZCQNF-UHFFFAOYSA-N 0.000 claims 2
- 229960003854 delmopinol Drugs 0.000 claims 2
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical class C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 claims 2
- QOLIPNRNLBQTAU-UHFFFAOYSA-N flavan Chemical compound C1CC2=CC=CC=C2OC1C1=CC=CC=C1 QOLIPNRNLBQTAU-UHFFFAOYSA-N 0.000 claims 2
- 229930003935 flavonoid Natural products 0.000 claims 2
- 150000002215 flavonoids Chemical class 0.000 claims 2
- 235000017173 flavonoids Nutrition 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 150000002241 furanones Chemical class 0.000 claims 2
- 229960004867 hexetidine Drugs 0.000 claims 2
- FVYXIJYOAGAUQK-UHFFFAOYSA-N honokiol Chemical compound C1=C(CC=C)C(O)=CC=C1C1=CC(CC=C)=CC=C1O FVYXIJYOAGAUQK-UHFFFAOYSA-N 0.000 claims 2
- VVOAZFWZEDHOOU-UHFFFAOYSA-N honokiol Natural products OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 claims 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 2
- 239000011976 maleic acid Substances 0.000 claims 2
- 239000004309 nisin Substances 0.000 claims 2
- 235000010297 nisin Nutrition 0.000 claims 2
- 229950002404 octapinol Drugs 0.000 claims 2
- 229960001774 octenidine Drugs 0.000 claims 2
- SMGTYJPMKXNQFY-UHFFFAOYSA-N octenidine dihydrochloride Chemical compound Cl.Cl.C1=CC(=NCCCCCCCC)C=CN1CCCCCCCCCCN1C=CC(=NCCCCCCCC)C=C1 SMGTYJPMKXNQFY-UHFFFAOYSA-N 0.000 claims 2
- 150000002978 peroxides Chemical class 0.000 claims 2
- 229920005646 polycarboxylate Polymers 0.000 claims 2
- 239000011148 porous material Substances 0.000 claims 2
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 claims 2
- XWCIXXXLOAAWPU-UHFFFAOYSA-N prop-1-enylphosphonic acid Chemical compound CC=CP(O)(O)=O XWCIXXXLOAAWPU-UHFFFAOYSA-N 0.000 claims 2
- 229940069949 propolis Drugs 0.000 claims 2
- WKEDVNSFRWHDNR-UHFFFAOYSA-N salicylanilide Chemical compound OC1=CC=CC=C1C(=O)NC1=CC=CC=C1 WKEDVNSFRWHDNR-UHFFFAOYSA-N 0.000 claims 2
- 229950000975 salicylanilide Drugs 0.000 claims 2
- 229940084560 sanguinarine Drugs 0.000 claims 2
- YZRQUTZNTDAYPJ-UHFFFAOYSA-N sanguinarine pseudobase Natural products C1=C2OCOC2=CC2=C3N(C)C(O)C4=C(OCO5)C5=CC=C4C3=CC=C21 YZRQUTZNTDAYPJ-UHFFFAOYSA-N 0.000 claims 2
- 239000000377 silicon dioxide Substances 0.000 claims 2
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- 229910001432 tin ion Inorganic materials 0.000 claims 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 2
- 229960003500 triclosan Drugs 0.000 claims 2
- 229940096998 ursolic acid Drugs 0.000 claims 2
- PLSAJKYPRJGMHO-UHFFFAOYSA-N ursolic acid Natural products CC1CCC2(CCC3(C)C(C=CC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(=O)O PLSAJKYPRJGMHO-UHFFFAOYSA-N 0.000 claims 2
- 239000000341 volatile oil Substances 0.000 claims 2
- 230000002087 whitening effect Effects 0.000 claims 2
- RYJDNPSQBGFFSF-WCCKRBBISA-N (2s)-2-amino-5-(diaminomethylideneamino)pentanoic acid;carbonic acid Chemical compound OC(O)=O.OC(=O)[C@@H](N)CCCNC(N)=N RYJDNPSQBGFFSF-WCCKRBBISA-N 0.000 claims 1
- OIDIRWZVUWCCCO-UHFFFAOYSA-N 1-ethylpyridin-1-ium Chemical compound CC[N+]1=CC=CC=C1 OIDIRWZVUWCCCO-UHFFFAOYSA-N 0.000 claims 1
- 108010062877 Bacteriocins Proteins 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims 1
- 241000218378 Magnolia Species 0.000 claims 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 230000002272 anti-calculus Effects 0.000 claims 1
- 150000001483 arginine derivatives Chemical class 0.000 claims 1
- 230000001680 brushing effect Effects 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000007937 lozenge Substances 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 150000002823 nitrates Chemical group 0.000 claims 1
- 235000010333 potassium nitrate Nutrition 0.000 claims 1
- 239000004323 potassium nitrate Substances 0.000 claims 1
- 235000013024 sodium fluoride Nutrition 0.000 claims 1
- 239000011775 sodium fluoride Substances 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/356,837 US20090186090A1 (en) | 2007-04-30 | 2009-01-21 | Oral Care Composition to Reduce or Eliminate Dental Sensitivity |
| US12/356,837 | 2009-01-21 | ||
| PCT/US2010/021582 WO2010090855A2 (en) | 2009-01-21 | 2010-01-21 | Oral care composition to reduce or eliminate dental sensitivity |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015150966A Division JP2015232013A (ja) | 2009-01-21 | 2015-07-30 | 歯の敏感性を低減する、または除去するための口腔ケア組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012515780A JP2012515780A (ja) | 2012-07-12 |
| JP2012515780A5 true JP2012515780A5 (enExample) | 2013-03-14 |
| JP5865081B2 JP5865081B2 (ja) | 2016-02-17 |
Family
ID=42542590
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011548085A Expired - Fee Related JP5865081B2 (ja) | 2009-01-21 | 2010-01-21 | 歯の敏感性を低減する、または除去するための口腔ケア組成物 |
| JP2015150966A Withdrawn JP2015232013A (ja) | 2009-01-21 | 2015-07-30 | 歯の敏感性を低減する、または除去するための口腔ケア組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015150966A Withdrawn JP2015232013A (ja) | 2009-01-21 | 2015-07-30 | 歯の敏感性を低減する、または除去するための口腔ケア組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20090186090A1 (enExample) |
| EP (1) | EP2389228A2 (enExample) |
| JP (2) | JP5865081B2 (enExample) |
| CN (1) | CN102292125A (enExample) |
| AR (1) | AR075043A1 (enExample) |
| AU (1) | AU2010210890B2 (enExample) |
| BR (1) | BRPI1007053B1 (enExample) |
| CA (1) | CA2749189C (enExample) |
| CO (1) | CO6382144A2 (enExample) |
| MX (1) | MX2011007235A (enExample) |
| MY (1) | MY159576A (enExample) |
| RU (1) | RU2011134912A (enExample) |
| SG (1) | SG172780A1 (enExample) |
| TW (1) | TWI558419B (enExample) |
| WO (1) | WO2010090855A2 (enExample) |
| ZA (1) | ZA201104856B (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI395595B (zh) * | 2009-04-01 | 2013-05-11 | Colgate Palmolive Co | 用於治療牙齒敏感之口腔用組成物及其使用方法與製造 |
| MX376901B (es) | 2010-03-31 | 2025-03-07 | Colgate Palmolive Co | Composicion para el cuidado oral. |
| CN102811698B (zh) | 2010-03-31 | 2016-01-13 | 高露洁-棕榄公司 | 口腔护理组合物 |
| WO2011162756A1 (en) | 2010-06-23 | 2011-12-29 | Colgate-Palmolive Company | Therapeutic oral composition |
| SG190023A1 (en) * | 2010-12-07 | 2013-06-28 | Colgate Palmolive Co | Dentifrice compositions containing calcium silicate |
| US9717929B2 (en) | 2010-12-07 | 2017-08-01 | Colgate-Palmolive Company | Dentifrice compositions containing calcium silicate and a basic amino acid |
| PH12013501078A1 (en) | 2010-12-20 | 2018-03-21 | Colgate Palmolive Co | Gelatin encapsulated oral care composition containing hydrophilic active hydrophobic structuring agent and oil carrier |
| CA2825139C (en) | 2011-01-31 | 2017-04-04 | Colgate-Palmolive Company | Oral care compositions |
| US8932060B2 (en) * | 2011-09-30 | 2015-01-13 | Kuraray Noritake Dental Inc. | Dental treatment method |
| US9333154B2 (en) * | 2012-01-12 | 2016-05-10 | M & O Solutions, Llc | Dual component oral composition for enhancing remineralization of teeth |
| CN104411287A (zh) | 2012-06-29 | 2015-03-11 | 高露洁-棕榄公司 | 包含微晶纤维素和羧甲基纤维素的高水含量口腔组合物 |
| US9134219B2 (en) * | 2012-08-31 | 2015-09-15 | Johnson & Johnson Consumer Inc. | Permeability flow cell and hydraulic conductance system |
| US9134217B2 (en) * | 2012-08-31 | 2015-09-15 | Johnson & Johnson Consumer Inc. | Permeability flow cell and hydraulic conductance system |
| JP6199871B2 (ja) | 2012-09-05 | 2017-09-20 | 株式会社サンギ | 口腔用組成物 |
| US20160067167A1 (en) * | 2012-11-15 | 2016-03-10 | Isp Investments Inc. | Oral care compositions for treatment of sensitive teeth |
| US20150374590A1 (en) * | 2013-03-19 | 2015-12-31 | University Of Washington Through Its Center For Commercialization | Artificial teeth |
| WO2015046491A1 (ja) * | 2013-09-30 | 2015-04-02 | クラレノリタケデンタル株式会社 | １材型の象牙細管封鎖材 |
| PT3137051T (pt) | 2014-04-28 | 2020-01-10 | Visionaturolab Inc | Composição de cuidados orais compreendendo pó de osso de choco e suas utilizações |
| US9927422B2 (en) * | 2014-05-13 | 2018-03-27 | The Procter & Gamble Company | Method and device for measuring dentin permeability |
| CN104188855B (zh) * | 2014-08-20 | 2017-04-12 | 广州立白企业集团有限公司 | 一种具有预防和缓解牙齿敏感作用的中药牙膏 |
| CN106999392A (zh) * | 2014-12-19 | 2017-08-01 | 高露洁-棕榄公司 | 牙齿美白口腔护理产品 |
| MX365971B (es) * | 2015-04-29 | 2019-06-21 | Colgate Palmolive Co | Composiciones para el cuidado bucal. |
| WO2017182240A1 (en) * | 2016-04-18 | 2017-10-26 | Unilever Plc | Oral care composition |
| USD823469S1 (en) | 2016-04-18 | 2018-07-17 | Conopco Inc. | Tooth cleaning appliance |
| KR102000521B1 (ko) * | 2017-03-02 | 2019-07-17 | 주식회사 지에이치바이오텍 | 구강 스프레이용 조성물 |
| CN107569395B (zh) * | 2017-09-04 | 2020-08-11 | 天津医科大学口腔医院 | 一种用于封闭牙本质小管使牙齿脱敏的材料 |
| US11033096B2 (en) | 2017-12-12 | 2021-06-15 | Colgate-Palmolive Company | Oral care refill head and oral care kit including the same |
| AU2017443357B2 (en) * | 2017-12-18 | 2022-01-27 | Gaba International Holding Gmbh | Oral care compositions |
| MX385755B (es) | 2018-03-29 | 2025-03-18 | Procter & Gamble | Composiciones para el cuidado bucal para promover la salud de las encias |
| JP7058341B2 (ja) | 2018-03-29 | 2022-04-21 | ザ プロクター アンド ギャンブル カンパニー | 歯肉健康を促進するための口腔ケア組成物 |
| CN111989083B (zh) | 2018-03-29 | 2024-02-13 | 宝洁公司 | 用于促进牙龈健康的口腔护理组合物 |
| MX383559B (es) | 2018-03-29 | 2025-03-14 | Procter & Gamble | Composiciones para el cuidado bucal para promover la salud de las encias |
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| WO2021062631A1 (en) | 2019-09-30 | 2021-04-08 | The Procter & Gamble Company | Dentifrice compositions for treatment of dental biofilm |
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| CN113908067B (zh) * | 2021-10-19 | 2024-03-19 | 四川涑爽医疗用品有限公司 | 一种抗牙齿敏感的组合物及其制备方法与应用、包含该组合物的口腔护理产品 |
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- 2009-01-21 US US12/356,837 patent/US20090186090A1/en not_active Abandoned
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2010
- 2010-01-21 JP JP2011548085A patent/JP5865081B2/ja not_active Expired - Fee Related
- 2010-01-21 TW TW099101691A patent/TWI558419B/zh not_active IP Right Cessation
- 2010-01-21 SG SG2011046182A patent/SG172780A1/en unknown
- 2010-01-21 CN CN2010800054232A patent/CN102292125A/zh active Pending
- 2010-01-21 MX MX2011007235A patent/MX2011007235A/es active IP Right Grant
- 2010-01-21 WO PCT/US2010/021582 patent/WO2010090855A2/en not_active Ceased
- 2010-01-21 EP EP10701595A patent/EP2389228A2/en not_active Ceased
- 2010-01-21 BR BRPI1007053-2A patent/BRPI1007053B1/pt not_active IP Right Cessation
- 2010-01-21 RU RU2011134912/15A patent/RU2011134912A/ru unknown
- 2010-01-21 MY MYPI2011002993A patent/MY159576A/en unknown
- 2010-01-21 CA CA2749189A patent/CA2749189C/en active Active
- 2010-01-21 AU AU2010210890A patent/AU2010210890B2/en active Active
- 2010-01-21 AR ARP100100134A patent/AR075043A1/es unknown
-
2011
- 2011-06-30 ZA ZA2011/04856A patent/ZA201104856B/en unknown
- 2011-07-06 CO CO11084233A patent/CO6382144A2/es not_active Application Discontinuation
-
2015
- 2015-07-30 JP JP2015150966A patent/JP2015232013A/ja not_active Withdrawn
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