JP2012515780A5 - - Google Patents
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- Publication number
- JP2012515780A5 JP2012515780A5 JP2011548085A JP2011548085A JP2012515780A5 JP 2012515780 A5 JP2012515780 A5 JP 2012515780A5 JP 2011548085 A JP2011548085 A JP 2011548085A JP 2011548085 A JP2011548085 A JP 2011548085A JP 2012515780 A5 JP2012515780 A5 JP 2012515780A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- oral care
- silica particles
- tooth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 46
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 16
- 239000002245 particle Substances 0.000 claims 12
- 239000003795 chemical substances by application Substances 0.000 claims 11
- 238000000034 method Methods 0.000 claims 11
- 239000000853 adhesive Substances 0.000 claims 6
- 230000001070 adhesive effect Effects 0.000 claims 6
- 239000000551 dentifrice Substances 0.000 claims 5
- -1 fluoride compound Chemical class 0.000 claims 5
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 4
- INVGWHRKADIJHF-UHFFFAOYSA-N Sanguinarin Chemical compound C1=C2OCOC2=CC2=C3[N+](C)=CC4=C(OCO5)C5=CC=C4C3=CC=C21 INVGWHRKADIJHF-UHFFFAOYSA-N 0.000 claims 4
- 239000002253 acid Substances 0.000 claims 4
- 229960001927 cetylpyridinium chloride Drugs 0.000 claims 4
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 claims 4
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 229910052700 potassium Inorganic materials 0.000 claims 4
- 239000011591 potassium Substances 0.000 claims 4
- 210000005239 tubule Anatomy 0.000 claims 4
- ANAAMBRRWOGKGU-UHFFFAOYSA-M 4-ethyl-1-tetradecylpyridin-1-ium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC[N+]1=CC=C(CC)C=C1 ANAAMBRRWOGKGU-UHFFFAOYSA-M 0.000 claims 3
- 229940090898 Desensitizer Drugs 0.000 claims 3
- 210000004268 dentin Anatomy 0.000 claims 3
- 201000002170 dentin sensitivity Diseases 0.000 claims 3
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 230000036347 tooth sensitivity Effects 0.000 claims 3
- WCGUUGGRBIKTOS-GPOJBZKASA-N (3beta)-3-hydroxyurs-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C WCGUUGGRBIKTOS-GPOJBZKASA-N 0.000 claims 2
- DTOUUUZOYKYHEP-UHFFFAOYSA-N 1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine Chemical compound CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1 DTOUUUZOYKYHEP-UHFFFAOYSA-N 0.000 claims 2
- YFVBASFBIJFBAI-UHFFFAOYSA-M 1-tetradecylpyridin-1-ium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC[N+]1=CC=CC=C1 YFVBASFBIJFBAI-UHFFFAOYSA-M 0.000 claims 2
- RWMSXNCJNSILON-UHFFFAOYSA-N 2-[4-(2-propylpentyl)piperidin-1-yl]ethanol Chemical compound CCCC(CCC)CC1CCN(CCO)CC1 RWMSXNCJNSILON-UHFFFAOYSA-N 0.000 claims 2
- PGKQTZHDCHKDQK-UHFFFAOYSA-N 2-phenylethenylphosphonic acid Chemical compound OP(O)(=O)C=CC1=CC=CC=C1 PGKQTZHDCHKDQK-UHFFFAOYSA-N 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims 2
- 241000209507 Camellia Species 0.000 claims 2
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims 2
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- FCEXWTOTHXCQCQ-UHFFFAOYSA-N Ethoxydihydrosanguinarine Natural products C12=CC=C3OCOC3=C2C(OCC)N(C)C(C2=C3)=C1C=CC2=CC1=C3OCO1 FCEXWTOTHXCQCQ-UHFFFAOYSA-N 0.000 claims 2
- BYTORXDZJWWIKR-UHFFFAOYSA-N Hinokiol Natural products CC(C)c1cc2CCC3C(C)(CO)C(O)CCC3(C)c2cc1O BYTORXDZJWWIKR-UHFFFAOYSA-N 0.000 claims 2
- 240000000950 Hippophae rhamnoides Species 0.000 claims 2
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 108010053775 Nisin Proteins 0.000 claims 2
- NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 claims 2
- SRIJLARXVRHZKD-UHFFFAOYSA-N OP(O)=O.C=CC1=CC=CC=C1 Chemical compound OP(O)=O.C=CC1=CC=CC=C1 SRIJLARXVRHZKD-UHFFFAOYSA-N 0.000 claims 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 2
- 241000241413 Propolis Species 0.000 claims 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 2
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims 2
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 claims 2
- LFVVNPBBFUSSHL-UHFFFAOYSA-N alexidine Chemical compound CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC LFVVNPBBFUSSHL-UHFFFAOYSA-N 0.000 claims 2
- 229950010221 alexidine Drugs 0.000 claims 2
- 125000000129 anionic group Chemical group 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 2
- 229960000686 benzalkonium chloride Drugs 0.000 claims 2
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims 2
- 229960003260 chlorhexidine Drugs 0.000 claims 2
- 235000018597 common camellia Nutrition 0.000 claims 2
- 229910001431 copper ion Inorganic materials 0.000 claims 2
- 229960003624 creatine Drugs 0.000 claims 2
- 239000006046 creatine Substances 0.000 claims 2
- 230000001186 cumulative effect Effects 0.000 claims 2
- QSFOWAYMMZCQNF-UHFFFAOYSA-N delmopinol Chemical compound CCCC(CCC)CCCC1COCCN1CCO QSFOWAYMMZCQNF-UHFFFAOYSA-N 0.000 claims 2
- 229960003854 delmopinol Drugs 0.000 claims 2
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical class C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 claims 2
- QOLIPNRNLBQTAU-UHFFFAOYSA-N flavan Chemical compound C1CC2=CC=CC=C2OC1C1=CC=CC=C1 QOLIPNRNLBQTAU-UHFFFAOYSA-N 0.000 claims 2
- 229930003935 flavonoid Natural products 0.000 claims 2
- 150000002215 flavonoids Chemical class 0.000 claims 2
- 235000017173 flavonoids Nutrition 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 150000002241 furanones Chemical class 0.000 claims 2
- 229960004867 hexetidine Drugs 0.000 claims 2
- FVYXIJYOAGAUQK-UHFFFAOYSA-N honokiol Chemical compound C1=C(CC=C)C(O)=CC=C1C1=CC(CC=C)=CC=C1O FVYXIJYOAGAUQK-UHFFFAOYSA-N 0.000 claims 2
- VVOAZFWZEDHOOU-UHFFFAOYSA-N honokiol Natural products OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 claims 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 2
- 239000011976 maleic acid Substances 0.000 claims 2
- 239000004309 nisin Substances 0.000 claims 2
- 235000010297 nisin Nutrition 0.000 claims 2
- 229950002404 octapinol Drugs 0.000 claims 2
- 229960001774 octenidine Drugs 0.000 claims 2
- SMGTYJPMKXNQFY-UHFFFAOYSA-N octenidine dihydrochloride Chemical compound Cl.Cl.C1=CC(=NCCCCCCCC)C=CN1CCCCCCCCCCN1C=CC(=NCCCCCCCC)C=C1 SMGTYJPMKXNQFY-UHFFFAOYSA-N 0.000 claims 2
- 150000002978 peroxides Chemical class 0.000 claims 2
- 229920005646 polycarboxylate Polymers 0.000 claims 2
- 239000011148 porous material Substances 0.000 claims 2
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 claims 2
- XWCIXXXLOAAWPU-UHFFFAOYSA-N prop-1-enylphosphonic acid Chemical compound CC=CP(O)(O)=O XWCIXXXLOAAWPU-UHFFFAOYSA-N 0.000 claims 2
- 229940069949 propolis Drugs 0.000 claims 2
- WKEDVNSFRWHDNR-UHFFFAOYSA-N salicylanilide Chemical compound OC1=CC=CC=C1C(=O)NC1=CC=CC=C1 WKEDVNSFRWHDNR-UHFFFAOYSA-N 0.000 claims 2
- 229950000975 salicylanilide Drugs 0.000 claims 2
- 229940084560 sanguinarine Drugs 0.000 claims 2
- YZRQUTZNTDAYPJ-UHFFFAOYSA-N sanguinarine pseudobase Natural products C1=C2OCOC2=CC2=C3N(C)C(O)C4=C(OCO5)C5=CC=C4C3=CC=C21 YZRQUTZNTDAYPJ-UHFFFAOYSA-N 0.000 claims 2
- 239000000377 silicon dioxide Substances 0.000 claims 2
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- 229910001432 tin ion Inorganic materials 0.000 claims 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 2
- 229960003500 triclosan Drugs 0.000 claims 2
- 229940096998 ursolic acid Drugs 0.000 claims 2
- PLSAJKYPRJGMHO-UHFFFAOYSA-N ursolic acid Natural products CC1CCC2(CCC3(C)C(C=CC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(=O)O PLSAJKYPRJGMHO-UHFFFAOYSA-N 0.000 claims 2
- 239000000341 volatile oil Substances 0.000 claims 2
- 230000002087 whitening effect Effects 0.000 claims 2
- RYJDNPSQBGFFSF-WCCKRBBISA-N (2s)-2-amino-5-(diaminomethylideneamino)pentanoic acid;carbonic acid Chemical compound OC(O)=O.OC(=O)[C@@H](N)CCCNC(N)=N RYJDNPSQBGFFSF-WCCKRBBISA-N 0.000 claims 1
- OIDIRWZVUWCCCO-UHFFFAOYSA-N 1-ethylpyridin-1-ium Chemical compound CC[N+]1=CC=CC=C1 OIDIRWZVUWCCCO-UHFFFAOYSA-N 0.000 claims 1
- 108010062877 Bacteriocins Proteins 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims 1
- 241000218378 Magnolia Species 0.000 claims 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 230000002272 anti-calculus Effects 0.000 claims 1
- 150000001483 arginine derivatives Chemical class 0.000 claims 1
- 230000001680 brushing effect Effects 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000007937 lozenge Substances 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 150000002823 nitrates Chemical group 0.000 claims 1
- 235000010333 potassium nitrate Nutrition 0.000 claims 1
- 239000004323 potassium nitrate Substances 0.000 claims 1
- 235000013024 sodium fluoride Nutrition 0.000 claims 1
- 239000011775 sodium fluoride Substances 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/356,837 | 2009-01-21 | ||
| US12/356,837 US20090186090A1 (en) | 2007-04-30 | 2009-01-21 | Oral Care Composition to Reduce or Eliminate Dental Sensitivity |
| PCT/US2010/021582 WO2010090855A2 (en) | 2009-01-21 | 2010-01-21 | Oral care composition to reduce or eliminate dental sensitivity |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015150966A Division JP2015232013A (ja) | 2009-01-21 | 2015-07-30 | 歯の敏感性を低減する、または除去するための口腔ケア組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012515780A JP2012515780A (ja) | 2012-07-12 |
| JP2012515780A5 true JP2012515780A5 (enExample) | 2013-03-14 |
| JP5865081B2 JP5865081B2 (ja) | 2016-02-17 |
Family
ID=42542590
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011548085A Expired - Fee Related JP5865081B2 (ja) | 2009-01-21 | 2010-01-21 | 歯の敏感性を低減する、または除去するための口腔ケア組成物 |
| JP2015150966A Withdrawn JP2015232013A (ja) | 2009-01-21 | 2015-07-30 | 歯の敏感性を低減する、または除去するための口腔ケア組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015150966A Withdrawn JP2015232013A (ja) | 2009-01-21 | 2015-07-30 | 歯の敏感性を低減する、または除去するための口腔ケア組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20090186090A1 (enExample) |
| EP (1) | EP2389228A2 (enExample) |
| JP (2) | JP5865081B2 (enExample) |
| CN (1) | CN102292125A (enExample) |
| AR (1) | AR075043A1 (enExample) |
| AU (1) | AU2010210890B2 (enExample) |
| BR (1) | BRPI1007053B1 (enExample) |
| CA (1) | CA2749189C (enExample) |
| CO (1) | CO6382144A2 (enExample) |
| MX (1) | MX2011007235A (enExample) |
| MY (1) | MY159576A (enExample) |
| RU (1) | RU2011134912A (enExample) |
| SG (1) | SG172780A1 (enExample) |
| TW (1) | TWI558419B (enExample) |
| WO (1) | WO2010090855A2 (enExample) |
| ZA (1) | ZA201104856B (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR076180A1 (es) * | 2009-04-01 | 2011-05-26 | Colgate Palmolive Co | Composiciones de uso oral para el tratamiento de la sensibilidad dental y metodos para su produccion y utilizacion |
| CA2791551C (en) | 2010-03-31 | 2015-10-13 | Colgate-Palmolive Company | Oral care composition comprising metal oxide particles and a polymeric adherent material |
| SG183905A1 (en) | 2010-03-31 | 2012-10-30 | Colgate Palmolive Co | Oral care composition |
| WO2011162756A1 (en) | 2010-06-23 | 2011-12-29 | Colgate-Palmolive Company | Therapeutic oral composition |
| MX341155B (es) * | 2010-12-07 | 2016-08-09 | Colgate Palmolive Co | Composiciones de dentifricos que contienen silicato de calcio. |
| US9717929B2 (en) | 2010-12-07 | 2017-08-01 | Colgate-Palmolive Company | Dentifrice compositions containing calcium silicate and a basic amino acid |
| EP2654500B1 (en) | 2010-12-20 | 2017-07-19 | Colgate-Palmolive Company | Gelatin encapsulated oral care composition containing hydrophilic active, hydrophobic structuring agent and oil carrier |
| JP2014505077A (ja) | 2011-01-31 | 2014-02-27 | コルゲート・パーモリブ・カンパニー | オーラルケア組成物 |
| US8932060B2 (en) * | 2011-09-30 | 2015-01-13 | Kuraray Noritake Dental Inc. | Dental treatment method |
| US9333154B2 (en) * | 2012-01-12 | 2016-05-10 | M & O Solutions, Llc | Dual component oral composition for enhancing remineralization of teeth |
| EP2866774B1 (en) | 2012-06-29 | 2017-08-09 | Colgate-Palmolive Company | High water content oral compositions comprising microcrystalline cellulose and carboxymethylcellulose |
| US9134217B2 (en) * | 2012-08-31 | 2015-09-15 | Johnson & Johnson Consumer Inc. | Permeability flow cell and hydraulic conductance system |
| US9134219B2 (en) * | 2012-08-31 | 2015-09-15 | Johnson & Johnson Consumer Inc. | Permeability flow cell and hydraulic conductance system |
| CN104736127B (zh) | 2012-09-05 | 2017-06-13 | 三仪股份有限公司 | 口腔用组合物 |
| EP2919750A4 (en) * | 2012-11-15 | 2016-05-11 | Isp Investments Inc | ORAL CARE COMPOSITIONS FOR THE TREATMENT OF SENSITIVE TEETH |
| US20150374590A1 (en) * | 2013-03-19 | 2015-12-31 | University Of Washington Through Its Center For Commercialization | Artificial teeth |
| EP3053570B1 (en) * | 2013-09-30 | 2018-11-21 | Kuraray Noritake Dental Inc. | One-component-type dentinal tubule sealant |
| PL3137051T3 (pl) | 2014-04-28 | 2020-06-01 | Visionaturolab Inc. | Kompozycja do pielęgnacji jamy ustnej zawierająca proszek z kości mątwy i jej zastosowania |
| US9927422B2 (en) * | 2014-05-13 | 2018-03-27 | The Procter & Gamble Company | Method and device for measuring dentin permeability |
| CN104188855B (zh) * | 2014-08-20 | 2017-04-12 | 广州立白企业集团有限公司 | 一种具有预防和缓解牙齿敏感作用的中药牙膏 |
| CA2971162A1 (en) * | 2014-12-19 | 2016-06-23 | Colgate-Palmolive Company | Tooth whitening oral care product |
| WO2016176180A1 (en) * | 2015-04-29 | 2016-11-03 | Colgate-Palmolive Company | Oral care compositions |
| CN109069364A (zh) * | 2016-04-18 | 2018-12-21 | 荷兰联合利华有限公司 | 口腔护理组合物 |
| USD823469S1 (en) | 2016-04-18 | 2018-07-17 | Conopco Inc. | Tooth cleaning appliance |
| KR102000521B1 (ko) * | 2017-03-02 | 2019-07-17 | 주식회사 지에이치바이오텍 | 구강 스프레이용 조성물 |
| CN107569395B (zh) * | 2017-09-04 | 2020-08-11 | 天津医科大学口腔医院 | 一种用于封闭牙本质小管使牙齿脱敏的材料 |
| US11033096B2 (en) | 2017-12-12 | 2021-06-15 | Colgate-Palmolive Company | Oral care refill head and oral care kit including the same |
| AU2017443357B2 (en) * | 2017-12-18 | 2022-01-27 | Gaba International Holding Gmbh | Oral care compositions |
| CN111989081B (zh) | 2018-03-29 | 2023-12-05 | 宝洁公司 | 用于促进牙龈健康的口腔护理组合物 |
| JP7058341B2 (ja) | 2018-03-29 | 2022-04-21 | ザ プロクター アンド ギャンブル カンパニー | 歯肉健康を促進するための口腔ケア組成物 |
| CN111989083B (zh) | 2018-03-29 | 2024-02-13 | 宝洁公司 | 用于促进牙龈健康的口腔护理组合物 |
| AU2018415261B2 (en) | 2018-03-29 | 2021-11-04 | The Procter & Gamble Company | Oral care compositions for promoting gum health |
| CN113242751B (zh) | 2018-12-18 | 2023-09-19 | 联合利华知识产权控股有限公司 | 抗微生物组合物 |
| US11304888B2 (en) | 2019-04-29 | 2022-04-19 | Sunstar Americas, Inc. | Oral care composition |
| WO2021062631A1 (en) | 2019-09-30 | 2021-04-08 | The Procter & Gamble Company | Dentifrice compositions for treatment of dental biofilm |
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| AU2019468928B2 (en) | 2019-09-30 | 2024-02-29 | The Procter & Gamble Company | Dentifrice compositions for treatment of dental biofilm |
| CA3155925A1 (en) | 2019-09-30 | 2021-04-08 | The Procter & Gamble Company | Oral care compositions with anticaries activity |
| CN115052574A (zh) * | 2020-01-29 | 2022-09-13 | 兔子个人卫生用品工贸有限公司 | 用于维护整个口腔健康的有机与无机成分协同作用的口服组合物及其获取方法和用途 |
| CN113908067B (zh) * | 2021-10-19 | 2024-03-19 | 四川涑爽医疗用品有限公司 | 一种抗牙齿敏感的组合物及其制备方法与应用、包含该组合物的口腔护理产品 |
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| CN118164493B (zh) * | 2024-02-29 | 2024-11-05 | 金三江(肇庆)硅材料股份有限公司 | 一种二氧化硅颗粒及其制备方法、口腔清洁护理组合物 |
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2009
- 2009-01-21 US US12/356,837 patent/US20090186090A1/en not_active Abandoned
-
2010
- 2010-01-21 MX MX2011007235A patent/MX2011007235A/es active IP Right Grant
- 2010-01-21 AU AU2010210890A patent/AU2010210890B2/en active Active
- 2010-01-21 AR ARP100100134A patent/AR075043A1/es unknown
- 2010-01-21 TW TW099101691A patent/TWI558419B/zh not_active IP Right Cessation
- 2010-01-21 SG SG2011046182A patent/SG172780A1/en unknown
- 2010-01-21 MY MYPI2011002993A patent/MY159576A/en unknown
- 2010-01-21 RU RU2011134912/15A patent/RU2011134912A/ru unknown
- 2010-01-21 WO PCT/US2010/021582 patent/WO2010090855A2/en not_active Ceased
- 2010-01-21 EP EP10701595A patent/EP2389228A2/en not_active Ceased
- 2010-01-21 CA CA2749189A patent/CA2749189C/en active Active
- 2010-01-21 JP JP2011548085A patent/JP5865081B2/ja not_active Expired - Fee Related
- 2010-01-21 BR BRPI1007053-2A patent/BRPI1007053B1/pt not_active IP Right Cessation
- 2010-01-21 CN CN2010800054232A patent/CN102292125A/zh active Pending
-
2011
- 2011-06-30 ZA ZA2011/04856A patent/ZA201104856B/en unknown
- 2011-07-06 CO CO11084233A patent/CO6382144A2/es not_active Application Discontinuation
-
2015
- 2015-07-30 JP JP2015150966A patent/JP2015232013A/ja not_active Withdrawn
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