JP2012513758A5 - - Google Patents
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- Publication number
- JP2012513758A5 JP2012513758A5 JP2011543724A JP2011543724A JP2012513758A5 JP 2012513758 A5 JP2012513758 A5 JP 2012513758A5 JP 2011543724 A JP2011543724 A JP 2011543724A JP 2011543724 A JP2011543724 A JP 2011543724A JP 2012513758 A5 JP2012513758 A5 JP 2012513758A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- sequence
- oligonucleotides
- complementary
- provider
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091034117 Oligonucleotide Proteins 0.000 claims description 400
- 230000000295 complement effect Effects 0.000 claims description 172
- 239000002773 nucleotide Substances 0.000 claims description 160
- 125000003729 nucleotide group Chemical group 0.000 claims description 160
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims description 146
- 241000186781 Listeria Species 0.000 claims description 138
- 150000007523 nucleic acids Chemical class 0.000 claims description 136
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 74
- 108020004707 nucleic acids Proteins 0.000 claims description 63
- 102000039446 nucleic acids Human genes 0.000 claims description 63
- 238000000034 method Methods 0.000 claims description 59
- 108020004465 16S ribosomal RNA Proteins 0.000 claims description 53
- 241000588724 Escherichia coli Species 0.000 claims description 53
- 230000003321 amplification Effects 0.000 claims description 36
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 36
- 238000003556 assay Methods 0.000 claims description 34
- 238000001514 detection method Methods 0.000 claims description 26
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 claims description 24
- 229930024421 Adenine Natural products 0.000 claims description 12
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 claims description 12
- 229960000643 adenine Drugs 0.000 claims description 12
- 241000186779 Listeria monocytogenes Species 0.000 claims description 4
- 241000206605 Brochothrix Species 0.000 claims description 3
- 239000000523 sample Substances 0.000 description 11
- RXNXLAHQOVLMIE-UHFFFAOYSA-N phenyl 10-methylacridin-10-ium-9-carboxylate Chemical compound C12=CC=CC=C2[N+](C)=C2C=CC=CC2=C1C(=O)OC1=CC=CC=C1 RXNXLAHQOVLMIE-UHFFFAOYSA-N 0.000 description 3
- 210000003705 ribosome Anatomy 0.000 description 2
- 239000012634 fragment Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14165108P | 2008-12-30 | 2008-12-30 | |
| US61/141,651 | 2008-12-30 | ||
| PCT/US2009/069746 WO2010078374A1 (en) | 2008-12-30 | 2009-12-29 | Compositions, kits and related methods for the detection and/or monitoring of listeria |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014127931A Division JP2014168483A (ja) | 2008-12-30 | 2014-06-23 | Ｌｉｓｔｅｒｉａを検出およびモニターするための組成物、キットおよび関連する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012513758A JP2012513758A (ja) | 2012-06-21 |
| JP2012513758A5 true JP2012513758A5 (https=) | 2013-02-07 |
| JP5793085B2 JP5793085B2 (ja) | 2015-10-14 |
Family
ID=41682839
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543724A Active JP5793085B2 (ja) | 2008-12-30 | 2009-12-29 | Ｌｉｓｔｅｒｉａを検出およびモニターするための組成物、キットおよび関連する方法 |
| JP2014127931A Withdrawn JP2014168483A (ja) | 2008-12-30 | 2014-06-23 | Ｌｉｓｔｅｒｉａを検出およびモニターするための組成物、キットおよび関連する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014127931A Withdrawn JP2014168483A (ja) | 2008-12-30 | 2014-06-23 | Ｌｉｓｔｅｒｉａを検出およびモニターするための組成物、キットおよび関連する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US8748133B2 (https=) |
| EP (2) | EP2910647A1 (https=) |
| JP (2) | JP5793085B2 (https=) |
| AU (1) | AU2009335053B2 (https=) |
| CA (1) | CA2746539A1 (https=) |
| WO (1) | WO2010078374A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5319281B2 (ja) * | 2005-07-26 | 2013-10-16 | ユニバーシティ オブ メディシン アンド デンティストリー オブ ニュージャージー | エキノカンジン系薬物に対する耐性の分析法並びに同分析法のためのオリゴヌクレオチド・セット及び試薬キット |
| EP2910647A1 (en) | 2008-12-30 | 2015-08-26 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of listeria |
| US12203884B2 (en) | 2019-03-21 | 2025-01-21 | The United States Of America, As Represented By The Secretary Of Agriculture | Flow-through electrochemical detection system |
| US11371073B2 (en) | 2020-03-11 | 2022-06-28 | The United States Of America, As Represented By The Secretary Of Agriculture | Listeria detection |
| US12221651B2 (en) * | 2021-03-30 | 2025-02-11 | The United States Of America, As Represented By The Secretary Of Agriculture | Polynucleotide detection system |
Family Cites Families (53)
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|---|---|---|---|---|
| FR2422956A1 (fr) | 1978-04-13 | 1979-11-09 | Pasteur Institut | Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede |
| US6414152B1 (en) | 1981-12-11 | 2002-07-02 | University Of Wales College Of Medicine Of Heath Park | Luminescent labelling material and procedures |
| FI63596C (fi) | 1981-10-16 | 1983-07-11 | Orion Yhtymae Oy | Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser |
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| US6060237A (en) | 1985-02-26 | 2000-05-09 | Biostar, Inc. | Devices and methods for optical detection of nucleic acid hybridization |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4751177A (en) | 1985-06-13 | 1988-06-14 | Amgen | Methods and kits for performing nucleic acid hybridization assays |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5541308A (en) | 1986-11-24 | 1996-07-30 | Gen-Probe Incorporated | Nucleic acid probes for detection and/or quantitation of non-viral organisms |
| DE3708541A1 (de) | 1987-03-17 | 1988-10-13 | Agfa Gevaert Ag | Haertungsmittel fuer proteine, eine damit gehaertete bindemittelschicht und ein eine solche schicht enthaltendes fotografisches aufzeichnungsmaterial |
| US5089386A (en) * | 1987-09-11 | 1992-02-18 | Gene-Trak Systems | Test for listeria |
| US6004745A (en) | 1987-09-21 | 1999-12-21 | Gen-Probe Incorporated | Hybridization protection assay |
| US5585481A (en) | 1987-09-21 | 1996-12-17 | Gen-Probe Incorporated | Linking reagents for nucleotide probes |
| US6031091A (en) | 1987-09-21 | 2000-02-29 | Gen-Probe Incorporated | Non-nucleotide linking reagents for nucleotide probes |
| US5639604A (en) | 1987-09-21 | 1997-06-17 | Gen-Probe Incorporated | Homogeneous protection assay |
| US5185439A (en) | 1987-10-05 | 1993-02-09 | Gen-Probe Incorporated | Acridinium ester labelling and purification of nucleotide probes |
| US5030557A (en) | 1987-11-24 | 1991-07-09 | Ml Technology Venture | Means and method for enhancing nucleic acid hybridization |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| US5118801A (en) | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
| CA2002076A1 (en) | 1988-11-21 | 1990-05-21 | Brent A. Burdick | Diagnostic kit and method using a solid phase capture means for detecting nucleic acids |
| US5656207A (en) | 1989-06-24 | 1997-08-12 | Gen Probe Incorporated | Detecting or quantifying multiple analytes using labelling techniques |
| CA2020958C (en) | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
| WO1991001384A1 (en) | 1989-07-11 | 1991-02-07 | Gen-Probe, Incorporated | Nucleic acid sequence amplification methods utilizing a transcription complex |
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
| US5270184A (en) | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
| AU687352B2 (en) | 1992-06-08 | 1998-02-26 | Gen-Probe Incorporated | Preparation of nucleic acid from mononuclear cells |
| US5398491A (en) | 1992-10-13 | 1995-03-21 | Honda Giken Kogyo Kabushiki Kaisha | Lawn mower side discharge chute |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| KR100230909B1 (ko) | 1993-11-29 | 1999-12-01 | 다니엘 엘. 캐시앙 | 광범위의 유기체로부터 핵산 추출 방법 |
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| DE69535240T2 (de) | 1994-10-28 | 2007-06-06 | Gen-Probe Inc., San Diego | Zusammensetzungen und Verfahren für die gleichzeitige Detektion und Quantifizierung von einer Mehrheit spezifischer Nuklein Säure Sequenzen |
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| ATE292191T1 (de) * | 1996-02-28 | 2005-04-15 | Biomerieux Bv | Primer und sonden zur amplifizierung, erkennung und typisierung von mycoplasma pneumoniae |
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| JP2000514307A (ja) | 1996-07-16 | 2000-10-31 | ジェン―プローブ・インコーポレーテッド | 増加した標的特異的ｔ▲下ｍ▼を持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法 |
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| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| EP0975807B1 (en) | 1997-05-02 | 2006-09-27 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| US6534273B2 (en) | 1997-05-02 | 2003-03-18 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| US6794499B2 (en) | 1997-09-12 | 2004-09-21 | Exiqon A/S | Oligonucleotide analogues |
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| US20050142584A1 (en) * | 2003-10-01 | 2005-06-30 | Willson Richard C. | Microbial identification based on the overall composition of characteristic oligonucleotides |
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| US7575864B2 (en) * | 2004-05-27 | 2009-08-18 | E.I. Du Pont De Nemours And Company | Method for the direct detection of diagnostic RNA |
| CA2572472C (en) | 2004-07-01 | 2013-08-13 | Gen-Probe Incorporated | Methods and compositions to detect nucleic acids in a biological sample |
| CA2957197C (en) | 2004-08-27 | 2017-12-12 | Gen-Probe Incorporated | Single-primer nucleic acid amplification methods |
| US7964413B2 (en) | 2005-03-10 | 2011-06-21 | Gen-Probe Incorporated | Method for continuous mode processing of multiple reaction receptacles in a real-time amplification assay |
| EP1978111B1 (en) * | 2007-04-02 | 2013-03-27 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa |
| US10316352B2 (en) * | 2008-05-13 | 2019-06-11 | Gen-Probe Incorporated | Methods of capturing a target nucleic acid for amplification and detection using an inactivatable target capture oligomer |
| EP2910647A1 (en) | 2008-12-30 | 2015-08-26 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of listeria |
-
2009
- 2009-12-29 EP EP15155337.7A patent/EP2910647A1/en not_active Withdrawn
- 2009-12-29 AU AU2009335053A patent/AU2009335053B2/en not_active Ceased
- 2009-12-29 JP JP2011543724A patent/JP5793085B2/ja active Active
- 2009-12-29 EP EP09795674.2A patent/EP2389449B1/en not_active Not-in-force
- 2009-12-29 US US12/649,249 patent/US8748133B2/en active Active
- 2009-12-29 WO PCT/US2009/069746 patent/WO2010078374A1/en not_active Ceased
- 2009-12-29 CA CA2746539A patent/CA2746539A1/en not_active Abandoned
-
2014
- 2014-05-02 US US14/268,107 patent/US9593383B2/en active Active
- 2014-06-23 JP JP2014127931A patent/JP2014168483A/ja not_active Withdrawn
-
2017
- 2017-02-03 US US15/424,052 patent/US10501812B2/en active Active
-
2019
- 2019-10-25 US US16/663,642 patent/US11198913B2/en active Active
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