JP2012512815A5 - - Google Patents

Download PDF

Info

Publication number
JP2012512815A5
JP2012512815A5 JP2011541030A JP2011541030A JP2012512815A5 JP 2012512815 A5 JP2012512815 A5 JP 2012512815A5 JP 2011541030 A JP2011541030 A JP 2011541030A JP 2011541030 A JP2011541030 A JP 2011541030A JP 2012512815 A5 JP2012512815 A5 JP 2012512815A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
antagonist
composition according
subject
csf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011541030A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012512815A (ja
JP5727379B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/AU2009/001672 external-priority patent/WO2010071924A1/en
Publication of JP2012512815A publication Critical patent/JP2012512815A/ja
Publication of JP2012512815A5 publication Critical patent/JP2012512815A5/ja
Application granted granted Critical
Publication of JP5727379B2 publication Critical patent/JP5727379B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011541030A 2008-12-22 2009-12-21 変形性関節症の治療 Active JP5727379B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13967908P 2008-12-22 2008-12-22
US61/139,679 2008-12-22
US16448609P 2009-03-30 2009-03-30
US61/164,486 2009-03-30
PCT/AU2009/001672 WO2010071924A1 (en) 2008-12-22 2009-12-21 Osteoarthritis treatment

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015031198A Division JP2015143233A (ja) 2008-12-22 2015-02-20 変形性関節症の治療

Publications (3)

Publication Number Publication Date
JP2012512815A JP2012512815A (ja) 2012-06-07
JP2012512815A5 true JP2012512815A5 (enExample) 2013-02-14
JP5727379B2 JP5727379B2 (ja) 2015-06-03

Family

ID=42286786

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2011541030A Active JP5727379B2 (ja) 2008-12-22 2009-12-21 変形性関節症の治療
JP2015031198A Pending JP2015143233A (ja) 2008-12-22 2015-02-20 変形性関節症の治療
JP2017114806A Active JP6458086B2 (ja) 2008-12-22 2017-06-12 変形性関節症の治療

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015031198A Pending JP2015143233A (ja) 2008-12-22 2015-02-20 変形性関節症の治療
JP2017114806A Active JP6458086B2 (ja) 2008-12-22 2017-06-12 変形性関節症の治療

Country Status (19)

Country Link
US (4) US9243061B2 (enExample)
EP (2) EP3056217B1 (enExample)
JP (3) JP5727379B2 (enExample)
KR (2) KR101898982B1 (enExample)
CN (2) CN102271705A (enExample)
AU (1) AU2009329814B2 (enExample)
BR (1) BRPI0918356B1 (enExample)
CA (1) CA2746827C (enExample)
CY (1) CY1117698T1 (enExample)
DK (1) DK2376121T4 (enExample)
ES (2) ES2572368T5 (enExample)
HK (1) HK1226938A1 (enExample)
HR (1) HRP20160577T4 (enExample)
HU (1) HUE028615T2 (enExample)
PL (1) PL2376121T5 (enExample)
RU (2) RU2712273C2 (enExample)
SI (2) SI2376121T2 (enExample)
SM (1) SMT201600156B (enExample)
WO (1) WO2010071924A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2978209T3 (es) 2008-12-22 2024-09-09 Univ Melbourne Tratamiento del dolor
RU2712273C2 (ru) 2008-12-22 2020-01-28 Де Юниверсити Оф Мельбурн Лечение остеоартрита
UA117228C2 (uk) 2012-09-20 2018-07-10 Морфосис Аґ Фармацевтична композиція, що містить антитіло до gm-csf
DE102013222200A1 (de) * 2013-10-31 2015-08-27 Osram Opto Semiconductors Gmbh Elektronisches Bauelement und Verfahren zum Herstellen eines elektronischen Bauelements
AU2018318425A1 (en) * 2017-08-14 2020-02-27 Zynerba Pharmaceuticals, Inc. Methods of treatment of osteoarthritis with transdermal cannabidiol gel
WO2020104833A1 (en) * 2018-11-19 2020-05-28 4P-Pharma Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production
CN110075304B (zh) * 2019-05-29 2020-02-11 四川大学华西医院 一种治疗骨关节炎的药物组合物及其用途

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) * 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
IL95061A0 (en) 1989-07-14 1991-06-10 Schering Corp Antagonists of gm-csf derived from the carboxyl terminus
EP0486572B1 (en) 1989-08-11 1998-01-07 Amrad Corporation Limited Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof
WO1994009149A1 (en) 1990-08-10 1994-04-28 Amrad Corporation Limited Monoclonal antibody
WO1994011404A1 (en) 1992-11-19 1994-05-26 Dana-Farber Cancer Institute Antibodies for gm-csf receptor and uses thereof
CA2229043C (en) 1995-08-18 2016-06-07 Morphosys Gesellschaft Fur Proteinoptimierung Mbh Protein/(poly)peptide libraries
AUPP525198A0 (en) 1998-08-13 1998-09-03 Medvet Science Pty. Ltd. Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof
US7108852B2 (en) 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
US7455836B2 (en) * 2000-05-08 2008-11-25 The University Of Melbourne Method of treatment and agents useful for same
WO2003035048A2 (en) * 2001-10-26 2003-05-01 Novartis Ag Methods for the treatment of osteoarthritis and compositions thereof
ES2365606T3 (es) 2002-02-13 2011-10-07 Ludwig Institute For Cancer Research Ltd. Anticuerpos contra gm-csf quiméricos.
US20040241755A1 (en) * 2003-06-02 2004-12-02 Pfizer Inc. Human cell assay to determine effect of sample compounds on Col2 enhancer expression
BRPI0506679A (pt) 2004-02-11 2007-05-15 Warner Lambert Co métodos de tratar osteoartrite com antagonistas de il-6
ES2465141T3 (es) * 2004-03-31 2014-06-05 Kazuwa Nakao Remedio o medicamento preventivo para la artritis
EP1593690B1 (en) 2004-05-05 2009-07-01 Micromet AG Preparation of ScFv antibody fragments
US7662573B2 (en) 2004-08-18 2010-02-16 The United States Of America As Represented By The Department Of Health And Human Services Methods for evaluating osteoarthritis risk
US20060040258A1 (en) 2004-08-23 2006-02-23 Huiyan Guo Water-soluble conjugates and methods of preparation
KR20150091193A (ko) 2005-04-18 2015-08-07 암젠 리서치 (뮌헨) 게엠베하 인간 과립구 마크로파지 콜로니 자극 인자의 중화 항체
BRPI0610796B8 (pt) * 2005-05-18 2021-05-25 Morphosys Ag anticorpo humano ou humanizado isolado, ou um fragmento fab ou scfv do mesmo, sequência de ácidos nucleicos, vetor, e, uso de um anticorpo
JP4736037B2 (ja) 2005-10-26 2011-07-27 株式会社イーベック ヒトgm−csfに結合するヒトのモノクローナル抗体並びにその抗原結合部分
EP1957537A2 (en) * 2005-12-01 2008-08-20 Domantis Limited Competitive domain antibody formats that bind interleukin 1 receptor type 1
RS55526B1 (sr) * 2006-02-08 2017-05-31 Morphotek Inc Antigenski gm-csf peptidi i antitela gm-csf
CN101443360B (zh) * 2006-03-27 2013-11-27 医学免疫有限公司 Gm-csf受体结合元件
US7741273B2 (en) 2006-04-13 2010-06-22 Warsaw Orthopedic, Inc. Drug depot implant designs
CN105435223A (zh) * 2006-11-21 2016-03-30 卡罗拜奥斯制药公司 使用gm-csf拮抗剂治疗慢性炎症疾病的方法
WO2008080134A2 (en) * 2006-12-22 2008-07-03 Rigel Pharmaceuticals, Inc. 4-amin0-2- (hetero) arylamino-5- (hetero) arylthiazoles useful as axl inhibitors
EP2160407A4 (en) 2007-05-23 2011-07-27 Crc For Asthma And Airways Ltd NEUTRALIZING ANTIBODIES
TW200918553A (en) 2007-09-18 2009-05-01 Amgen Inc Human GM-CSF antigen binding proteins
US20090163440A1 (en) * 2007-09-26 2009-06-25 Waddell David D Ion-Channel Regulator Compositions and Methods of Using Same
EP2217626A4 (en) 2007-11-12 2011-06-22 Crc For Asthma And Airways Ltd EPITOP FOR NEUTRALIZING ANTIBODIES
BRPI0820530A2 (pt) * 2007-11-13 2015-06-16 Boehringer Ingelheim Int Anticorpos monoclonais que se ligam ao hgm-csf e composições medicinais compreendendo os mesmos
WO2009118662A2 (en) 2008-03-24 2009-10-01 Abbott Biotechnology Ltd. Methods and compositions for treating bone loss
EA201001691A1 (ru) 2008-04-28 2011-10-31 Калобайос Фармасьютикалз, Инк. Антитела к гранулоцитарно-макрофагальному колониестимулирующему фактору
RU2712273C2 (ru) * 2008-12-22 2020-01-28 Де Юниверсити Оф Мельбурн Лечение остеоартрита
ES2978209T3 (es) 2008-12-22 2024-09-09 Univ Melbourne Tratamiento del dolor
US8609101B2 (en) 2009-04-23 2013-12-17 Theraclone Sciences, Inc. Granulocyte-macrophage colony-stimulating factor (GM-CSF) neutralizing antibodies

Similar Documents

Publication Publication Date Title
JP2012512814A5 (enExample)
CY1119474T1 (el) Κρυσταλλικες μορφες 5-χλωρο-ν2-(2-ισοπροποξυ-5-μεθυλ-4-πιπεριδιν-4-υλ-φαινυλ)-ν4[2-(προπανο-2-σουλφονυλ)-φαινυλ]-πυριμιδιν-2,4-διαμινης
IL227113B (en) Tamper resistant solid oral dosage forms
JP2009256391A5 (enExample)
JP2013514381A5 (enExample)
JP2013014622A5 (enExample)
JP2011006431A5 (enExample)
JP2012512815A5 (enExample)
CN104812762A8 (en) Substituted annulated pyrimidines and triazines, and use thereof
JP2013525444A5 (enExample)
IL209499A (en) Human monoclonal antibody against influenza virus a, Pharmaceutical preparations containing it and its use in drug preparation
EP2475427A4 (en) ACTRIIB ANTAGONISTS, THEIR DOSAGE AND APPLICATIONS THEREOF
BRPI0920082A2 (pt) forma de dosagem oral de acetaminofeno/tramadol com liberação estendida.
EA201101190A1 (ru) Фармацевтическая композиция, включающая линаглиптин и необязательно ингибитор sglt2, и ее применение
HUE046557T2 (hu) Tapentadolt tartalmazó vizes gyógyszerészeti készítmény szájon át alkalmazásra
AP2010005429A0 (en) The use of solid carrier particles to improve the processability of a pharmaceutical agent.
BRPI1015996A2 (pt) composições farmacêuticas aquosas contendo complexos de borato-poliol
DK2420223T3 (da) Vandige farmaceutiske sammensætninger med borat-polyol-komplekser
HUE052617T2 (hu) Oligoszacharid és eljárás elõállítására
SI2645992T1 (sl) Trdna oralna dozirna oblika z asimetrično obliko
EP2624815B8 (en) Oral vaccine fast-dissolving dosage form using starch
JP2012136529A5 (enExample)
EA201200616A1 (ru) Производные 2-оксо-1-пирролидинилимидазотиадиазола
EP2695897A4 (en) NEW ANTI-RECEPTOR ANTIBODY OF IL-23 HUMAN
EP2501225A4 (en) PHARMACEUTICAL COMPOSITION FROM MELANOCORTIN RECEPTOR LIGANDS