JP2012512815A5 - - Google Patents

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Publication number
JP2012512815A5
JP2012512815A5 JP2011541030A JP2011541030A JP2012512815A5 JP 2012512815 A5 JP2012512815 A5 JP 2012512815A5 JP 2011541030 A JP2011541030 A JP 2011541030A JP 2011541030 A JP2011541030 A JP 2011541030A JP 2012512815 A5 JP2012512815 A5 JP 2012512815A5
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JP
Japan
Prior art keywords
pharmaceutical composition
antagonist
composition according
subject
csf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011541030A
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English (en)
Japanese (ja)
Other versions
JP5727379B2 (ja
JP2012512815A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/AU2009/001672 external-priority patent/WO2010071924A1/en
Publication of JP2012512815A publication Critical patent/JP2012512815A/ja
Publication of JP2012512815A5 publication Critical patent/JP2012512815A5/ja
Application granted granted Critical
Publication of JP5727379B2 publication Critical patent/JP5727379B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011541030A 2008-12-22 2009-12-21 変形性関節症の治療 Active JP5727379B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13967908P 2008-12-22 2008-12-22
US61/139,679 2008-12-22
US16448609P 2009-03-30 2009-03-30
US61/164,486 2009-03-30
PCT/AU2009/001672 WO2010071924A1 (en) 2008-12-22 2009-12-21 Osteoarthritis treatment

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015031198A Division JP2015143233A (ja) 2008-12-22 2015-02-20 変形性関節症の治療

Publications (3)

Publication Number Publication Date
JP2012512815A JP2012512815A (ja) 2012-06-07
JP2012512815A5 true JP2012512815A5 (enExample) 2013-02-14
JP5727379B2 JP5727379B2 (ja) 2015-06-03

Family

ID=42286786

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2011541030A Active JP5727379B2 (ja) 2008-12-22 2009-12-21 変形性関節症の治療
JP2015031198A Pending JP2015143233A (ja) 2008-12-22 2015-02-20 変形性関節症の治療
JP2017114806A Active JP6458086B2 (ja) 2008-12-22 2017-06-12 変形性関節症の治療

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015031198A Pending JP2015143233A (ja) 2008-12-22 2015-02-20 変形性関節症の治療
JP2017114806A Active JP6458086B2 (ja) 2008-12-22 2017-06-12 変形性関節症の治療

Country Status (19)

Country Link
US (4) US9243061B2 (enExample)
EP (2) EP3056217B1 (enExample)
JP (3) JP5727379B2 (enExample)
KR (2) KR101799264B1 (enExample)
CN (2) CN106397591A (enExample)
AU (1) AU2009329814B2 (enExample)
BR (1) BRPI0918356B1 (enExample)
CA (1) CA2746827C (enExample)
CY (1) CY1117698T1 (enExample)
DK (1) DK2376121T4 (enExample)
ES (2) ES2886063T3 (enExample)
HK (1) HK1226938A1 (enExample)
HR (1) HRP20160577T4 (enExample)
HU (1) HUE028615T2 (enExample)
PL (1) PL2376121T5 (enExample)
RU (2) RU2712273C2 (enExample)
SI (2) SI2376121T2 (enExample)
SM (1) SMT201600156B (enExample)
WO (1) WO2010071924A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5674677B2 (ja) 2008-12-22 2015-02-25 ザ ユニバーシティー オブ メルボルンＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ ｏｆ Ｍｅｌｂｏｕｒｎｅ 疼痛治療
KR101799264B1 (ko) * 2008-12-22 2017-11-20 더 유니버시티 오브 멜버른 골관절염 치료
HK1208231A1 (en) 2012-09-20 2016-02-26 Morphosys Ag Treatment for rheumatoid arthritis
DE102013222200A1 (de) * 2013-10-31 2015-08-27 Osram Opto Semiconductors Gmbh Elektronisches Bauelement und Verfahren zum Herstellen eines elektronischen Bauelements
EP3668500A4 (en) * 2017-08-14 2021-04-28 Zynerba Pharmaceuticals, Inc. METHOD OF TREATMENT OF OSTEOARTHRITIS WITH TRANSDERMAL CANNABIDIOL GEL
WO2020104833A1 (en) * 2018-11-19 2020-05-28 4P-Pharma Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production
CN110075304B (zh) * 2019-05-29 2020-02-11 四川大学华西医院 一种治疗骨关节炎的药物组合物及其用途

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JPH04503815A (ja) 1989-07-14 1992-07-09 シェリング・コーポレーション カルボキシル末端から誘導されたｇｍ―ｃｓｆのアンタゴニスト
EP0486572B1 (en) 1989-08-11 1998-01-07 Amrad Corporation Limited Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof
US5747032A (en) 1990-08-10 1998-05-05 Amrad Corporation Limited Monoclonal antibody to human granulocyte macrophage colony stimulating factor
CA2149881A1 (en) 1992-11-19 1994-05-26 Paul T. Jubinsky Antibodies for gm-csf receptor and uses thereof
WO1997008320A1 (en) 1995-08-18 1997-03-06 Morphosys Gesellschaft Für Proteinoptimierung Mbh Protein/(poly)peptide libraries
AUPP525198A0 (en) 1998-08-13 1998-09-03 Medvet Science Pty. Ltd. Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof
US7108852B2 (en) 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
US7455836B2 (en) * 2000-05-08 2008-11-25 The University Of Melbourne Method of treatment and agents useful for same
JP2005507915A (ja) * 2001-10-26 2005-03-24 ノバルティス アクチエンゲゼルシャフト 変形性関節症の処置方法およびその組成物
JP2006500905A (ja) 2002-02-13 2006-01-12 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ ヒト化ｇｍ−ｃｓｆ抗体
US20040241755A1 (en) * 2003-06-02 2004-12-02 Pfizer Inc. Human cell assay to determine effect of sample compounds on Col2 enhancer expression
WO2005080429A2 (en) † 2004-02-11 2005-09-01 Warner-Lambert Company Llc Methods of treating osteoarthritis with anti-il-6 or anti-il6 receptor antibodies
JP4825667B2 (ja) * 2004-03-31 2011-11-30 一和 中尾 関節炎症治療剤又は予防剤
ATE435238T1 (de) 2004-05-05 2009-07-15 Micromet Ag Herstellung eines einkettigen fv antikörperfragments
EP1782074A2 (en) * 2004-08-18 2007-05-09 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Biomarkers for osteoarthritis
US20060040258A1 (en) 2004-08-23 2006-02-23 Huiyan Guo Water-soluble conjugates and methods of preparation
MX2007012569A (es) 2005-04-18 2007-12-06 Micromet Ag Neutralizadores de anticuerpos del factor estimulante de la colonia de macrofagos-granulocitos humanos.
PT1888643E (pt) † 2005-05-18 2015-01-14 Morphosys Ag Anticorpos anti-fec-gm e as respectivas utilizações
JP4736037B2 (ja) 2005-10-26 2011-07-27 株式会社イーベック ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分
CA2629850A1 (en) * 2005-12-01 2007-06-07 Domantis Limited Competitive domain antibody formats that bind interleukin 1 receptor type 1
KR101486183B1 (ko) * 2006-02-08 2015-01-28 모르포테크, 인크. 항원성 ｇｍ-ｃｓｆ 펩티드 및 ｇｍ-ｃｓｆ에 대한 항체
SI1999152T1 (sl) * 2006-03-27 2013-02-28 Medimmune Limited Vezni äślen za gm-csf receptor
US7741273B2 (en) * 2006-04-13 2010-06-22 Warsaw Orthopedic, Inc. Drug depot implant designs
CN101605547A (zh) 2006-11-21 2009-12-16 卡罗拜奥斯制药公司 使用gm-csf拮抗剂治疗慢性炎症疾病的方法
WO2008080134A2 (en) * 2006-12-22 2008-07-03 Rigel Pharmaceuticals, Inc. 4-amin0-2- (hetero) arylamino-5- (hetero) arylthiazoles useful as axl inhibitors
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TW200918553A (en) * 2007-09-18 2009-05-01 Amgen Inc Human GM-CSF antigen binding proteins
US20090163440A1 (en) * 2007-09-26 2009-06-25 Waddell David D Ion-Channel Regulator Compositions and Methods of Using Same
AU2008323608A1 (en) 2007-11-12 2009-05-22 Crc For Asthma And Airways Ltd Epitope for neutralizing antibodies
PL2215119T3 (pl) * 2007-11-13 2013-06-28 Evec Inc Przeciwciała monoklonalne, które wiążą się z hGM-CSF i kompozycje lecznicze je zawierające
US20100040630A1 (en) † 2008-03-24 2010-02-18 Aake Elden Methods and compositions for treating bone loss
WO2009134805A2 (en) * 2008-04-28 2009-11-05 Kalobios Pharmaceuticals, Inc. Antibodies to granulocyte-macrophage colony-stimulating factor
KR101799264B1 (ko) * 2008-12-22 2017-11-20 더 유니버시티 오브 멜버른 골관절염 치료
JP5674677B2 (ja) † 2008-12-22 2015-02-25 ザ ユニバーシティー オブ メルボルンＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ ｏｆ Ｍｅｌｂｏｕｒｎｅ 疼痛治療
WO2010124163A2 (en) 2009-04-23 2010-10-28 Theraclone Sciences, Inc. Granulocyte-macrophage colony-stimulating factor (gm-csf) neutralizing antibodies

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