JP2012512149A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012512149A5 JP2012512149A5 JP2011540141A JP2011540141A JP2012512149A5 JP 2012512149 A5 JP2012512149 A5 JP 2012512149A5 JP 2011540141 A JP2011540141 A JP 2011540141A JP 2011540141 A JP2011540141 A JP 2011540141A JP 2012512149 A5 JP2012512149 A5 JP 2012512149A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- linker
- conjugate
- iii
- platinum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000005647 linker group Chemical group 0.000 claims 15
- 239000002105 nanoparticle Substances 0.000 claims 7
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 6
- HRGDZIGMBDGFTC-UHFFFAOYSA-N platinum(2+) Chemical compound [Pt+2] HRGDZIGMBDGFTC-UHFFFAOYSA-N 0.000 claims 5
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims 4
- 229910052737 gold Inorganic materials 0.000 claims 4
- 239000010931 gold Substances 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000002077 nanosphere Substances 0.000 claims 2
- 229910052697 platinum Inorganic materials 0.000 claims 2
- -1 platinum (II) compound Chemical class 0.000 claims 2
- 229910052709 silver Inorganic materials 0.000 claims 2
- 239000004332 silver Substances 0.000 claims 2
- 125000004434 sulfur atom Chemical group 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 238000010255 intramuscular injection Methods 0.000 claims 1
- 239000007927 intramuscular injection Substances 0.000 claims 1
- 238000010253 intravenous injection Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 125000004430 oxygen atom Chemical group O* 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000004962 physiological condition Effects 0.000 claims 1
- 238000010254 subcutaneous injection Methods 0.000 claims 1
- 239000007929 subcutaneous injection Substances 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08171870.2 | 2008-12-16 | ||
| EP08171870 | 2008-12-16 | ||
| PCT/EP2009/067136 WO2010069941A1 (en) | 2008-12-16 | 2009-12-15 | Conjugates comprising nanoparticles coated with platinum containing compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012512149A JP2012512149A (ja) | 2012-05-31 |
| JP2012512149A5 true JP2012512149A5 (enExample) | 2012-11-29 |
| JP5873719B2 JP5873719B2 (ja) | 2016-03-01 |
Family
ID=40568646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011540141A Expired - Fee Related JP5873719B2 (ja) | 2008-12-16 | 2009-12-15 | 白金含有化合物被覆ナノ粒子を含有するコンジュゲート |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9023370B2 (enExample) |
| EP (1) | EP2379114B1 (enExample) |
| JP (1) | JP5873719B2 (enExample) |
| CA (1) | CA2745972C (enExample) |
| CY (1) | CY1115601T1 (enExample) |
| DK (1) | DK2379114T3 (enExample) |
| ES (1) | ES2505890T3 (enExample) |
| HR (1) | HRP20140804T1 (enExample) |
| IL (1) | IL213408A (enExample) |
| PL (1) | PL2379114T3 (enExample) |
| PT (1) | PT2379114E (enExample) |
| SI (1) | SI2379114T1 (enExample) |
| WO (1) | WO2010069941A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0909435D0 (en) * | 2009-06-02 | 2009-07-15 | Univ Strathclyde | Nanoparticle for biomolecule delivery |
| ES2392528B1 (es) * | 2010-12-28 | 2013-10-21 | Endor Nanotechnologies, S.L. | Sistema de liberación de agente terapéutico, composiciones farmacéuticas que lo contienen, su preparación y su uso médico. |
| ITRM20130138A1 (it) | 2013-03-07 | 2014-09-08 | Consiglio Nazionale Ricerche | Assemblato comprendente un assorbitore della luce nel vicino infrarosso legato covalentemente ad un inibitore dell'anidrasi carbonica |
| JP6316011B2 (ja) * | 2014-02-04 | 2018-04-25 | 国立大学法人滋賀医科大学 | 抗癌剤が担持されたナノ粒子 |
| EP3409772B1 (en) * | 2016-01-29 | 2023-06-28 | National University Corporation Hokkaido University | Intracellular substance transport system and use thereof |
| PL236093B1 (pl) | 2017-07-04 | 2020-11-30 | Dominika Szczepaniak | Rozpuszczalne w wodzie kompleksy złota (III), sposób wytwarzania rozpuszczalnych w wodzie kompleksów złota (III) i ich zastosowanie |
| EP3908324B1 (en) | 2019-01-08 | 2022-05-11 | Nanonica S.A. | Conjugates comprising nanoparticles coated with platinum derivatives through sulfonyl or phosphonyl-containing linkers |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR851932B (enExample) | 1984-08-14 | 1985-12-13 | Engelhard Corp | |
| JP2866554B2 (ja) | 1992-08-25 | 1999-03-08 | 松下電器産業株式会社 | 情報記録媒体とその製造方法及び情報記録媒体の使用方法 |
| CA2487720A1 (en) | 2002-06-03 | 2003-12-11 | Alnis Biosciences, Inc. | Therapeutic agent-containing polymeric nanoarticles |
| WO2006037081A2 (en) * | 2004-09-28 | 2006-04-06 | The Regents Of The University Of California | Nanoparticle radiosensitizers |
| US7601331B2 (en) * | 2004-11-10 | 2009-10-13 | National University Of Singapore | NIR-sensitive nanoparticle |
| US20060222595A1 (en) * | 2005-03-31 | 2006-10-05 | Priyabrata Mukherjee | Nanoparticles for therapeutic and diagnostic applications |
| US8785505B2 (en) * | 2005-10-28 | 2014-07-22 | The Regents Of The University Of California | Toxicology and cellular effect of manufactured nanomaterials |
-
2009
- 2009-12-15 JP JP2011540141A patent/JP5873719B2/ja not_active Expired - Fee Related
- 2009-12-15 CA CA2745972A patent/CA2745972C/en active Active
- 2009-12-15 PL PL09768395T patent/PL2379114T3/pl unknown
- 2009-12-15 US US13/140,347 patent/US9023370B2/en not_active Expired - Fee Related
- 2009-12-15 WO PCT/EP2009/067136 patent/WO2010069941A1/en not_active Ceased
- 2009-12-15 DK DK09768395.7T patent/DK2379114T3/da active
- 2009-12-15 HR HRP20140804AT patent/HRP20140804T1/hr unknown
- 2009-12-15 PT PT97683957T patent/PT2379114E/pt unknown
- 2009-12-15 SI SI200931018T patent/SI2379114T1/sl unknown
- 2009-12-15 EP EP09768395.7A patent/EP2379114B1/en not_active Not-in-force
- 2009-12-15 ES ES09768395.7T patent/ES2505890T3/es active Active
-
2011
- 2011-06-06 IL IL213408A patent/IL213408A/en active IP Right Grant
-
2014
- 2014-10-03 CY CY20141100802T patent/CY1115601T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012512149A5 (enExample) | ||
| JP2011511073A5 (enExample) | ||
| JP2012528240A5 (enExample) | ||
| HRP20140804T1 (hr) | Konjugati koji obuhvaä†aju nanoäśestice obložene tvarima koje sadrže platinu | |
| JP2010539082A5 (enExample) | ||
| Wang et al. | Fluorescent carbon dot-gated multifunctional mesoporous silica nanocarriers for redox/enzyme dual-responsive targeted and controlled drug delivery and real-time bioimaging | |
| CN102037058A (zh) | 多西紫杉醇高分子衍生物、及其制造方法及其用途 | |
| JP2011523643A5 (enExample) | ||
| JP2010528122A5 (enExample) | ||
| RU2013117441A (ru) | Пролекарства, содержащие конъюгат эксендин-линкер | |
| JP2010526917A5 (enExample) | ||
| WO2018171164A1 (zh) | 一种喜树碱类前药及其制备和应用 | |
| JP7764041B2 (ja) | 脳腫瘍における改善された血液脳関門浸透性及び滞留性を備えた、スケーラブルなチロインテグリンアンタゴニストの組成物 | |
| JP2018513875A5 (enExample) | ||
| JP2025534729A (ja) | α型葉酸受容体を標的とするペメトレキセド近赤外蛍光分子の蛍光トレーサーとしての用途 | |
| CN1241576C (zh) | 化学螯合剂用于制备逆转临床使用的神经肌肉传导阻滞剂药物诱发的神经肌肉传导阻滞的药物的用途 | |
| JP2007500734A5 (enExample) | ||
| CN107660210A (zh) | 基于硼替佐米的递送系统 | |
| CN102727905A (zh) | 一种金纳米-紫杉醇结合物及其制备方法和应用 | |
| WO2006098496A1 (ja) | ジアミノシクロヘキサン白金(ii)とブロック共重合体との配位化合物及びそれを含有する抗がん剤 | |
| CN108976318B (zh) | 单-6-(生物素酰胺基)-6-脱氧-β-环糊精及其制备方法和应用 | |
| TWI233929B (en) | Novel, water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases | |
| JP2007515399A5 (enExample) | ||
| JPWO2021200131A5 (enExample) | ||
| Bhattacharyya et al. | Synthesis of 1, 2, 3-triazole linked 5 fluorouracil-carbon dots-folate conjugates for target specific anticancer activity and cell imaging applications |