JP2012512149A5 - - Google Patents
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- Publication number
- JP2012512149A5 JP2012512149A5 JP2011540141A JP2011540141A JP2012512149A5 JP 2012512149 A5 JP2012512149 A5 JP 2012512149A5 JP 2011540141 A JP2011540141 A JP 2011540141A JP 2011540141 A JP2011540141 A JP 2011540141A JP 2012512149 A5 JP2012512149 A5 JP 2012512149A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- linker
- conjugate
- iii
- platinum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000005647 linker group Chemical group 0.000 claims 15
- 239000002105 nanoparticle Substances 0.000 claims 7
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 6
- HRGDZIGMBDGFTC-UHFFFAOYSA-N platinum(2+) Chemical compound [Pt+2] HRGDZIGMBDGFTC-UHFFFAOYSA-N 0.000 claims 5
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims 4
- 229910052737 gold Inorganic materials 0.000 claims 4
- 239000010931 gold Substances 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000002077 nanosphere Substances 0.000 claims 2
- 229910052697 platinum Inorganic materials 0.000 claims 2
- -1 platinum (II) compound Chemical class 0.000 claims 2
- 229910052709 silver Inorganic materials 0.000 claims 2
- 239000004332 silver Substances 0.000 claims 2
- 125000004434 sulfur atom Chemical group 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 238000010255 intramuscular injection Methods 0.000 claims 1
- 239000007927 intramuscular injection Substances 0.000 claims 1
- 238000010253 intravenous injection Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 125000004430 oxygen atom Chemical group O* 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000004962 physiological condition Effects 0.000 claims 1
- 238000010254 subcutaneous injection Methods 0.000 claims 1
- 239000007929 subcutaneous injection Substances 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08171870.2 | 2008-12-16 | ||
| EP08171870 | 2008-12-16 | ||
| PCT/EP2009/067136 WO2010069941A1 (en) | 2008-12-16 | 2009-12-15 | Conjugates comprising nanoparticles coated with platinum containing compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012512149A JP2012512149A (ja) | 2012-05-31 |
| JP2012512149A5 true JP2012512149A5 (enExample) | 2012-11-29 |
| JP5873719B2 JP5873719B2 (ja) | 2016-03-01 |
Family
ID=40568646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011540141A Expired - Fee Related JP5873719B2 (ja) | 2008-12-16 | 2009-12-15 | 白金含有化合物被覆ナノ粒子を含有するコンジュゲート |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9023370B2 (enExample) |
| EP (1) | EP2379114B1 (enExample) |
| JP (1) | JP5873719B2 (enExample) |
| CA (1) | CA2745972C (enExample) |
| CY (1) | CY1115601T1 (enExample) |
| DK (1) | DK2379114T3 (enExample) |
| ES (1) | ES2505890T3 (enExample) |
| HR (1) | HRP20140804T1 (enExample) |
| IL (1) | IL213408A (enExample) |
| PL (1) | PL2379114T3 (enExample) |
| PT (1) | PT2379114E (enExample) |
| SI (1) | SI2379114T1 (enExample) |
| WO (1) | WO2010069941A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0909435D0 (en) * | 2009-06-02 | 2009-07-15 | Univ Strathclyde | Nanoparticle for biomolecule delivery |
| ES2392528B1 (es) * | 2010-12-28 | 2013-10-21 | Endor Nanotechnologies, S.L. | Sistema de liberación de agente terapéutico, composiciones farmacéuticas que lo contienen, su preparación y su uso médico. |
| ITRM20130138A1 (it) | 2013-03-07 | 2014-09-08 | Consiglio Nazionale Ricerche | Assemblato comprendente un assorbitore della luce nel vicino infrarosso legato covalentemente ad un inibitore dell'anidrasi carbonica |
| JP6316011B2 (ja) * | 2014-02-04 | 2018-04-25 | 国立大学法人滋賀医科大学 | 抗癌剤が担持されたナノ粒子 |
| JP7018191B2 (ja) * | 2016-01-29 | 2022-02-10 | 国立大学法人北海道大学 | 細胞内物質移送システムおよびその利用 |
| PL236093B1 (pl) | 2017-07-04 | 2020-11-30 | Dominika Szczepaniak | Rozpuszczalne w wodzie kompleksy złota (III), sposób wytwarzania rozpuszczalnych w wodzie kompleksów złota (III) i ich zastosowanie |
| EP3908324B1 (en) | 2019-01-08 | 2022-05-11 | Nanonica S.A. | Conjugates comprising nanoparticles coated with platinum derivatives through sulfonyl or phosphonyl-containing linkers |
| TW202615847A (zh) * | 2024-09-27 | 2026-04-16 | 高雄醫學大學 | 檢測ｄｎａ甲基化的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR851932B (enExample) | 1984-08-14 | 1985-12-13 | Engelhard Corp | |
| JP2866554B2 (ja) | 1992-08-25 | 1999-03-08 | 松下電器産業株式会社 | 情報記録媒体とその製造方法及び情報記録媒体の使用方法 |
| JP2005535604A (ja) | 2002-06-03 | 2005-11-24 | アルニス バイオサイエンシーズ， インコーポレイテッド | 治療剤を含むポリマーナノ物品 |
| WO2006037081A2 (en) * | 2004-09-28 | 2006-04-06 | The Regents Of The University Of California | Nanoparticle radiosensitizers |
| US7601331B2 (en) * | 2004-11-10 | 2009-10-13 | National University Of Singapore | NIR-sensitive nanoparticle |
| US20060222595A1 (en) * | 2005-03-31 | 2006-10-05 | Priyabrata Mukherjee | Nanoparticles for therapeutic and diagnostic applications |
| US8785505B2 (en) * | 2005-10-28 | 2014-07-22 | The Regents Of The University Of California | Toxicology and cellular effect of manufactured nanomaterials |
-
2009
- 2009-12-15 US US13/140,347 patent/US9023370B2/en not_active Expired - Fee Related
- 2009-12-15 WO PCT/EP2009/067136 patent/WO2010069941A1/en not_active Ceased
- 2009-12-15 PT PT97683957T patent/PT2379114E/pt unknown
- 2009-12-15 HR HRP20140804AT patent/HRP20140804T1/hr unknown
- 2009-12-15 ES ES09768395.7T patent/ES2505890T3/es active Active
- 2009-12-15 CA CA2745972A patent/CA2745972C/en active Active
- 2009-12-15 SI SI200931018T patent/SI2379114T1/sl unknown
- 2009-12-15 PL PL09768395T patent/PL2379114T3/pl unknown
- 2009-12-15 DK DK09768395.7T patent/DK2379114T3/da active
- 2009-12-15 JP JP2011540141A patent/JP5873719B2/ja not_active Expired - Fee Related
- 2009-12-15 EP EP09768395.7A patent/EP2379114B1/en not_active Not-in-force
-
2011
- 2011-06-06 IL IL213408A patent/IL213408A/en active IP Right Grant
-
2014
- 2014-10-03 CY CY20141100802T patent/CY1115601T1/el unknown