JP2012511510A5 - - Google Patents
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- Publication number
- JP2012511510A5 JP2012511510A5 JP2011539060A JP2011539060A JP2012511510A5 JP 2012511510 A5 JP2012511510 A5 JP 2012511510A5 JP 2011539060 A JP2011539060 A JP 2011539060A JP 2011539060 A JP2011539060 A JP 2011539060A JP 2012511510 A5 JP2012511510 A5 JP 2012511510A5
- Authority
- JP
- Japan
- Prior art keywords
- alpha
- cis
- sodium
- octadecenoic acid
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052708 sodium Inorganic materials 0.000 claims 15
- 239000011734 sodium Substances 0.000 claims 15
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims 14
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 12
- 150000001875 compounds Chemical class 0.000 claims 8
- 230000003902 lesion Effects 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 5
- 239000005551 L01XE03 - Erlotinib Substances 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 3
- BPEGJWRSRHCHSN-UHFFFAOYSA-N Temozolomide Chemical compound O=C1N(C)N=NC2=C(C(N)=O)N=CN21 BPEGJWRSRHCHSN-UHFFFAOYSA-N 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 claims 3
- 229960004316 cisplatin Drugs 0.000 claims 3
- 239000002537 cosmetic Substances 0.000 claims 3
- AAKJLRGGTJKAMG-UHFFFAOYSA-N erlotinib Chemical compound C=12C=C(OCCOC)C(OCCOC)=CC2=NC=NC=1NC1=CC=CC(C#C)=C1 AAKJLRGGTJKAMG-UHFFFAOYSA-N 0.000 claims 3
- 229960001433 erlotinib Drugs 0.000 claims 3
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 claims 3
- 229960005277 gemcitabine Drugs 0.000 claims 3
- 229960004964 temozolomide Drugs 0.000 claims 3
- 208000008589 Obesity Diseases 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 210000005036 nerve Anatomy 0.000 claims 2
- 210000004126 nerve fiber Anatomy 0.000 claims 2
- 235000020824 obesity Nutrition 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000008929 regeneration Effects 0.000 claims 2
- 238000011069 regeneration method Methods 0.000 claims 2
- 229940083542 sodium Drugs 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- HSNQNPCNYIJJHT-ISLYRVAYSA-N trans-octadec-9-ene Chemical compound CCCCCCCC\C=C\CCCCCCCC HSNQNPCNYIJJHT-ISLYRVAYSA-N 0.000 claims 2
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- 206010020772 Hypertension Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002458 infectious effect Effects 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 230000002503 metabolic effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000000626 neurodegenerative effect Effects 0.000 claims 1
- 239000002417 nutraceutical Substances 0.000 claims 1
- 235000021436 nutraceutical agent Nutrition 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000037075 skin appearance Effects 0.000 claims 1
- 231100000444 skin lesion Toxicity 0.000 claims 1
- 206010040882 skin lesion Diseases 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 231100000216 vascular lesion Toxicity 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ESP200803480 | 2008-12-09 | ||
| ES200803480A ES2342997B1 (es) | 2008-12-09 | 2008-12-09 | Alpha derivados de acidos grasos cis-monoinsaturados para ser usados como medicamento. |
| PCT/ES2009/070561 WO2010066931A1 (es) | 2008-12-09 | 2009-12-04 | Alfa-derivados de ácidos grasos cis-monoinsaturados para ser usados como medicamento |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014232196A Division JP2015061856A (ja) | 2008-12-09 | 2014-11-14 | 薬物として使用するためのシス−一不飽和脂肪酸のα誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012511510A JP2012511510A (ja) | 2012-05-24 |
| JP2012511510A5 true JP2012511510A5 (enExample) | 2015-01-15 |
| JP5711140B2 JP5711140B2 (ja) | 2015-04-30 |
Family
ID=42242375
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011539060A Active JP5711140B2 (ja) | 2008-12-09 | 2009-12-04 | 薬物として使用するためのシス−一不飽和脂肪酸のα誘導体 |
| JP2014232196A Pending JP2015061856A (ja) | 2008-12-09 | 2014-11-14 | 薬物として使用するためのシス−一不飽和脂肪酸のα誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014232196A Pending JP2015061856A (ja) | 2008-12-09 | 2014-11-14 | 薬物として使用するためのシス−一不飽和脂肪酸のα誘導体 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US9000042B2 (enExample) |
| EP (4) | EP2842556B1 (enExample) |
| JP (2) | JP5711140B2 (enExample) |
| KR (1) | KR101683643B1 (enExample) |
| CN (1) | CN102355897B (enExample) |
| AU (6) | AU2009326993B2 (enExample) |
| BR (1) | BRPI0922870A8 (enExample) |
| CA (1) | CA2745052C (enExample) |
| DK (3) | DK2374453T3 (enExample) |
| ES (5) | ES2342997B1 (enExample) |
| HU (2) | HUE056170T2 (enExample) |
| IL (1) | IL213354A (enExample) |
| MX (1) | MX2011005978A (enExample) |
| PL (3) | PL2842556T3 (enExample) |
| PT (4) | PT3366285T (enExample) |
| RU (1) | RU2531353C2 (enExample) |
| SI (1) | SI3366285T1 (enExample) |
| WO (1) | WO2010066931A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2342997B1 (es) * | 2008-12-09 | 2011-06-06 | Universitat De Les Illes Balears | Alpha derivados de acidos grasos cis-monoinsaturados para ser usados como medicamento. |
| WO2011089265A1 (en) * | 2010-01-25 | 2011-07-28 | Bridge Bioresearch Plc | Use of fatty acid compounds for lowering blood glucose levels |
| ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
| WO2013132092A1 (en) | 2012-03-09 | 2013-09-12 | Pensieve International Plc | Use of monounsaturated fatty acid compounds for controlling the body weight of a dog or a cat |
| JP6348229B2 (ja) | 2014-10-21 | 2018-06-27 | ユニバーシタット デ レス イレス バレアレス | ヒドロキシ−トリグリセリドの合成方法、および疾患の予防および処置のためのその使用 |
| US11771672B2 (en) * | 2017-11-16 | 2023-10-03 | The Research Foundation For The State University Of New York | Use of 2-hydroxyoleic acid for the treatment of systemic lupus erythematosus and other immune pathologies |
| MX2022009035A (es) * | 2020-01-29 | 2022-08-11 | Univ Illes Balears | Metabolitos de acidos grasos alfa-hidroxilados, usos medicos de los mismos y uso como biomarcadores. |
| ES2911474B2 (es) * | 2020-11-17 | 2023-02-06 | Univ Illes Balears | Profarmacos de acidos grasos monoinsaturados y sus metabolitos: usos medicos y como biomarcadores |
| US12440467B2 (en) * | 2021-12-09 | 2025-10-14 | The Florida International University Board Of Trustees | Treatment and prevention of infections using vegetable oil-derived polyols |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4928172B1 (enExample) * | 1969-10-27 | 1974-07-24 | ||
| CH558321A (de) * | 1971-08-03 | 1975-01-31 | Ciba Geigy Ag | Verfahren zur herstellung von carbonsaeuren bezw. carbonsaeuresalzen. |
| US3931306A (en) | 1973-10-23 | 1976-01-06 | International Flavors & Fragrances Inc. | Process for producing isomer mixtures containing high proportions of cis-2-methyl-3-pentenoic acid |
| DE2448339A1 (de) * | 1974-10-10 | 1976-04-22 | Basf Ag | Verfahren zur herstellung von olefinisch ungesaettigten carbonsaeureestern |
| DE2559201B2 (de) * | 1975-12-30 | 1978-06-15 | Hoechst Ag, 6000 Frankfurt | Organozinnverbindungen und ihre Verwendung als Stabilisatoren |
| US4241097A (en) * | 1979-09-13 | 1980-12-23 | International Flavors & Fragrances Inc. | Use of benzodionones in augmenting or enhancing the aroma and taste of a foodstuff |
| US4391757A (en) * | 1981-11-27 | 1983-07-05 | Carstab Corporation | Organic antimony containing stabilizer compositions for halogenated polymers |
| JPS5899432A (ja) * | 1981-12-09 | 1983-06-13 | Maruzen Sekiyu Kagaku Kk | 不飽和脂肪酸またはその塩およびそれからなる抗菌剤 |
| US4551279A (en) | 1984-01-09 | 1985-11-05 | G. D. Searle & Co. | Protease inhibitors |
| FR2609032B1 (fr) * | 1986-12-30 | 1990-01-05 | Centre Nat Rech Scient | Epoxydes fonctionnels enantiomeriquement purs, leur procede de preparation et leur application comme synthons chiraux |
| US4808403A (en) * | 1987-03-17 | 1989-02-28 | International Flavors & Fragrances Inc. | Use of N,N-diethyl-m-toluamide and/or the ethyl ester of 2-methyl-3-pentenoic acid as insect attractants |
| US5504107A (en) | 1990-01-12 | 1996-04-02 | The Ohio State University Research Foundation | Optically pure 4-alkenyl- or 4-alkanyl-2-hydroxytetronic acids and pharmaceutical use thereof |
| GB9003201D0 (en) * | 1990-02-13 | 1990-04-11 | Unilever Plc | Cosmetic composition |
| US5208260A (en) * | 1990-03-29 | 1993-05-04 | G. D. Searle & Co. | Vinyl Glycine derivatives for memory and learning enhancement or treatment of a cognitive disorder |
| US5198250A (en) | 1990-07-16 | 1993-03-30 | Lipotech Partners Limited Partnership | Food and pharmaceutical compositions containing short chain monounsaturated fatty acids and methods of using |
| ES2039336T3 (es) * | 1991-04-10 | 1999-08-01 | Yu Ruey J | Uso de composiciones cosmeticas que contienen acidos 2-hidroxicarboxilicos y compuestos afines para aliviar los indicios de cambios de las uñas. |
| US6300373B1 (en) * | 1993-09-10 | 2001-10-09 | American Biogenetic Sciences, Inc. | Antiproliferative and neurotrophic molecules |
| JP3489703B2 (ja) * | 1995-10-23 | 2004-01-26 | 株式会社ノエビア | 微細エマルション組成物 |
| US5856537A (en) * | 1996-06-26 | 1999-01-05 | The Scripps Research Institute | Inhibitors of oleamide hydrolase |
| JPH10182338A (ja) * | 1996-12-20 | 1998-07-07 | Noevir Co Ltd | 水中油型乳化組成物 |
| JP2001523695A (ja) * | 1997-11-24 | 2001-11-27 | ザ スクリップス リサーチ インスティテュート | ギャップ結合連絡の阻害剤 |
| GB9926833D0 (en) * | 1999-11-15 | 2000-01-12 | Univ Sunderland | Compositions |
| GB2385589A (en) * | 2000-08-07 | 2003-08-27 | Sofitech Nv | Surfactant |
| ES2186576B1 (es) * | 2001-10-11 | 2004-09-16 | Universitat De Les Illes Balears | Acido 2-hidroxioleico para utilizar como medicamento. |
| US6702756B2 (en) * | 2001-12-11 | 2004-03-09 | University Technologies International Inc. | Method and apparatus for diagnosing neurological impairment |
| BR0306957A (pt) | 2002-01-22 | 2004-12-14 | Syngenta Participations Ag | Herbicidas |
| US7462349B2 (en) * | 2002-10-24 | 2008-12-09 | Nurit Kalderon | Beta interferon for the treatment of chronic spinal cord injury |
| US20040214215A1 (en) * | 2003-03-07 | 2004-10-28 | Yu Ruey J. | Bioavailability and improved delivery of alkaline pharmaceutical drugs |
| PL2537524T3 (pl) * | 2003-05-15 | 2017-01-31 | Ampio Pharmaceuticals, Inc. | Leczenie chorób mediowanych przez komórki T |
| ES2229935B1 (es) * | 2003-10-10 | 2006-10-01 | Universitat De Les Illes Balears | Utilizacion del acido hidroxioleico y compuestos analagos del mismo como aditivos alimentarios funcionales. |
| KR100756890B1 (ko) * | 2005-08-19 | 2007-09-07 | 경희대학교 산학협력단 | 신경세포 보호활성을 갖는 올레산을 함유하는 조성물 |
| JP2009051732A (ja) * | 2005-12-13 | 2009-03-12 | Meiji Seika Kaisha Ltd | Ｐｐａｒリガンド活性を有する組成物 |
| WO2009127009A1 (en) | 2008-04-18 | 2009-10-22 | Commonwealth Scientific And Industrial Research Organisation | Condensation polymers |
| US20120252967A1 (en) | 2008-04-18 | 2012-10-04 | Grains Research And Development Corporation | Polyurethanes |
| ES2342997B1 (es) | 2008-12-09 | 2011-06-06 | Universitat De Les Illes Balears | Alpha derivados de acidos grasos cis-monoinsaturados para ser usados como medicamento. |
-
2008
- 2008-12-09 ES ES200803480A patent/ES2342997B1/es active Active
-
2009
- 2009-12-04 SI SI200932141T patent/SI3366285T1/sl unknown
- 2009-12-04 ES ES14195394.3T patent/ES2673406T3/es active Active
- 2009-12-04 US US13/132,231 patent/US9000042B2/en active Active
- 2009-12-04 HU HUE18164265A patent/HUE056170T2/hu unknown
- 2009-12-04 ES ES14195436.2T patent/ES2661412T3/es active Active
- 2009-12-04 PL PL14195436T patent/PL2842556T3/pl unknown
- 2009-12-04 ES ES09831504.7T patent/ES2535498T3/es active Active
- 2009-12-04 RU RU2011128335/04A patent/RU2531353C2/ru active
- 2009-12-04 DK DK09831504.7T patent/DK2374453T3/en active
- 2009-12-04 DK DK18164265.3T patent/DK3366285T3/da active
- 2009-12-04 WO PCT/ES2009/070561 patent/WO2010066931A1/es not_active Ceased
- 2009-12-04 PT PT18164265T patent/PT3366285T/pt unknown
- 2009-12-04 EP EP14195436.2A patent/EP2842556B1/en active Active
- 2009-12-04 PL PL09831504T patent/PL2374453T3/pl unknown
- 2009-12-04 EP EP09831504.7A patent/EP2374453B1/en active Active
- 2009-12-04 EP EP14195394.3A patent/EP2842555B1/en active Active
- 2009-12-04 JP JP2011539060A patent/JP5711140B2/ja active Active
- 2009-12-04 CA CA2745052A patent/CA2745052C/en not_active Expired - Fee Related
- 2009-12-04 PT PT141954362T patent/PT2842556T/pt unknown
- 2009-12-04 PL PL18164265T patent/PL3366285T3/pl unknown
- 2009-12-04 CN CN200980156029.6A patent/CN102355897B/zh active Active
- 2009-12-04 EP EP18164265.3A patent/EP3366285B1/en active Active
- 2009-12-04 PT PT141953943T patent/PT2842555T/pt unknown
- 2009-12-04 DK DK14195436.2T patent/DK2842556T3/en active
- 2009-12-04 HU HUE14195436A patent/HUE037396T2/hu unknown
- 2009-12-04 MX MX2011005978A patent/MX2011005978A/es active IP Right Grant
- 2009-12-04 KR KR1020117014462A patent/KR101683643B1/ko not_active Expired - Fee Related
- 2009-12-04 PT PT98315047T patent/PT2374453E/pt unknown
- 2009-12-04 ES ES18164265T patent/ES2899274T3/es active Active
- 2009-12-04 BR BRPI0922870A patent/BRPI0922870A8/pt not_active Application Discontinuation
- 2009-12-04 AU AU2009326993A patent/AU2009326993B2/en not_active Revoked
-
2011
- 2011-06-05 IL IL213354A patent/IL213354A/en active IP Right Grant
-
2014
- 2014-11-14 JP JP2014232196A patent/JP2015061856A/ja active Pending
-
2015
- 2015-03-20 US US14/664,351 patent/US9730906B2/en active Active
-
2016
- 2016-09-13 AU AU2016228171A patent/AU2016228171A1/en not_active Abandoned
- 2016-09-13 AU AU2016228167A patent/AU2016228167A1/en not_active Abandoned
-
2017
- 2017-07-10 US US15/645,524 patent/US10588883B2/en active Active
-
2018
- 2018-09-12 AU AU2018229474A patent/AU2018229474B2/en active Active
- 2018-09-12 AU AU2018229472A patent/AU2018229472B2/en active Active
-
2019
- 2019-08-30 AU AU2019222955A patent/AU2019222955B2/en active Active
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