HRP20161197T1 - 24-norudca za liječenje autoimunog hepatitisa - Google Patents

24-norudca za liječenje autoimunog hepatitisa Download PDF

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Publication number
HRP20161197T1
HRP20161197T1 HRP20161197TT HRP20161197T HRP20161197T1 HR P20161197 T1 HRP20161197 T1 HR P20161197T1 HR P20161197T T HRP20161197T T HR P20161197TT HR P20161197 T HRP20161197 T HR P20161197T HR P20161197 T1 HRP20161197 T1 HR P20161197T1
Authority
HR
Croatia
Prior art keywords
autoimmune hepatitis
acceptable salts
ursodeoxycholic acid
norudca
pharmaceutically acceptable
Prior art date
Application number
HRP20161197TT
Other languages
English (en)
Inventor
Michael Trauner
Alan Hofmann
Peter Fickert
Original Assignee
Medizinische Universität Graz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medizinische Universität Graz filed Critical Medizinische Universität Graz
Publication of HRP20161197T1 publication Critical patent/HRP20161197T1/hr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Claims (3)

1. Nor-ursodeoksikolna kiselina i/ili njezine farmaceutski prihvatljive soli, naznačena/e time, da se upotrebljava(ju) u liječenju i/ili prevenciji autoimunog hepatitisa.
2. Nor-ursodeoksikolna kiselina i/ili njezine farmaceutski prihvatljive soli, koja/koje se upotrebljava(ju) u liječenju i/ili prevenciji autoimunog hepatitisa prema zahtjevu 1, naznačena/e time, da se nor-ursodeoksikolna kiselina i/ili njezine farmaceutski prihvatljive soli, formulira(ju) za oralnu, parenteralnu, subkutanu, intravenoznu, intramuskularnu, nazalnu, topikalnu ili rektalnu primjenu.
3. Nor-ursodeoksikolna kiselina i/ili njezine farmaceutski prihvatljive soli, koja/koje se upotrebljava(ju) u liječenju i/ili prevenciji autoimunog hepatitisa prema zahtjevima 1 ili 2, naznačena/e time, da se nor-ursodeoksikolna kiselina i/ili njezine farmaceutski prihvatljive soli, treba(ju) davati pacijentu u dnevnoj količini od 25 mg do 5 g, poželjno od 100 mg do 2,5 g, posebno od 800 mg do 1,5 g.
HRP20161197TT 2005-05-12 2016-09-19 24-norudca za liječenje autoimunog hepatitisa HRP20161197T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2005/052178 WO2006119803A1 (en) 2005-05-12 2005-05-12 USE OF 24-nor-UDCA
EP11176271.2A EP2392336B1 (en) 2005-05-12 2005-05-12 24-norUDCA for treating autoimmune hepatitis

Publications (1)

Publication Number Publication Date
HRP20161197T1 true HRP20161197T1 (hr) 2016-11-04

Family

ID=35457032

Family Applications (3)

Application Number Title Priority Date Filing Date
HRP20150949TT HRP20150949T1 (hr) 2005-05-12 2015-09-08 UPORABA 24-norUDCA
HRP20151091TT HRP20151091T1 (hr) 2005-05-12 2015-10-16 UPORABA 24-norUDCA
HRP20161197TT HRP20161197T1 (hr) 2005-05-12 2016-09-19 24-norudca za liječenje autoimunog hepatitisa

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HRP20150949TT HRP20150949T1 (hr) 2005-05-12 2015-09-08 UPORABA 24-norUDCA
HRP20151091TT HRP20151091T1 (hr) 2005-05-12 2015-10-16 UPORABA 24-norUDCA

Country Status (18)

Country Link
US (1) US8951995B2 (hr)
EP (4) EP2392337B1 (hr)
AU (1) AU2005331734B2 (hr)
CY (4) CY1116831T1 (hr)
DK (4) DK2392335T3 (hr)
EA (1) EA014077B1 (hr)
ES (4) ES2550204T3 (hr)
HK (1) HK1161122A1 (hr)
HR (3) HRP20150949T1 (hr)
HU (4) HUE025409T2 (hr)
LT (1) LT2392336T (hr)
ME (3) ME02737B (hr)
NO (1) NO340318B1 (hr)
PL (4) PL2392335T3 (hr)
PT (3) PT2392335E (hr)
RS (3) RS54185B1 (hr)
SI (4) SI1890705T1 (hr)
WO (1) WO2006119803A1 (hr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080275030A1 (en) 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
SI2182954T1 (sl) * 2007-07-25 2019-04-30 Medizinische Universitat Graz Uporaba nor-žolčnih kislin pri zdravljenju arterioskleroze
EP2468762A1 (en) * 2010-11-30 2012-06-27 Dr. Falk Pharma Gmbh Optimized synthesis of pure, non-polymorphic, crystalline bile acids with defined particle size
EP3461485A1 (en) 2017-09-28 2019-04-03 Dr. Falk Pharma Gmbh Use of nor-ursodeoxycholic acid for reducing liver fat
GB201911821D0 (en) 2019-08-16 2019-10-02 Provost Fellows Found Scholars And The Other Members Of Board Of The College Of The Holy And Undivid Compounds for use in the treatment of liver disease
US11372809B2 (en) * 2019-09-27 2022-06-28 Oracle International Corporation System and method for providing correlated content organization in an enterprise content management system based on a training set
WO2021130232A1 (en) 2019-12-23 2021-07-01 Medizinische Universität Wien Bile acid derivatives in the medical intervention of anxieties and/or stress symptoms
CN114195850B (zh) * 2020-09-18 2024-08-16 成都贝诺科成生物科技有限公司 一种用于防治肝病的化合物及其制药用途
WO2024023669A1 (en) * 2022-07-25 2024-02-01 Shilpa Medicare Limited Pharmaceutical compositions of nor-udca

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892868A (en) 1984-08-17 1990-01-09 Gipharmex, S.P.A. Derivatives of biliary acids, process for the production thereof and corresponding pharmaceutical compositions
IT1229569B (it) * 1989-04-17 1991-09-04 Giuliani Spa Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
IT1255449B (it) 1992-06-30 1995-10-31 Fabio Berlati Uso di nor- e omo-derivati di acidi biliari come promotori di assorbimento di farmaci.
TW289020B (hr) 1993-05-08 1996-10-21 Hoechst Sktiengesellschaft
ITMI20012572A1 (it) 2001-12-06 2003-06-06 Istituto Biochimico Italiano Microgranuli di acido ursodesossicolico

Also Published As

Publication number Publication date
CY1116831T1 (el) 2017-03-15
ES2547127T3 (es) 2015-10-01
EP2392335A3 (en) 2011-12-28
US20090163459A1 (en) 2009-06-25
DK2392335T3 (en) 2015-06-29
DK2392336T3 (en) 2016-09-05
HRP20151091T1 (hr) 2015-11-06
RS55180B1 (sr) 2017-01-31
DK2392337T3 (en) 2015-09-28
EA200702336A1 (ru) 2008-04-28
ME02544B (me) 2017-02-20
NO20076405L (no) 2008-02-11
RS54185B1 (en) 2015-12-31
PL2392337T3 (pl) 2015-12-31
HUE025409T2 (en) 2016-02-29
US8951995B2 (en) 2015-02-10
PL2392336T3 (pl) 2016-12-30
EP2392337B1 (en) 2015-07-29
EP1890705B1 (en) 2015-11-11
PL2392335T3 (pl) 2015-10-30
EA014077B1 (ru) 2010-08-30
CY1116840T1 (el) 2017-03-15
PT2392337E (pt) 2015-11-02
ME02256B (me) 2015-12-31
EP2392337A2 (en) 2011-12-07
HUE028336T2 (en) 2016-12-28
AU2005331734A1 (en) 2006-11-16
EP1890705A1 (en) 2008-02-27
PT2392336T (pt) 2016-10-04
EP2392335B1 (en) 2015-06-24
HRP20150949T1 (hr) 2015-12-04
AU2005331734B2 (en) 2012-04-19
SI1890705T1 (sl) 2016-02-29
PT2392335E (pt) 2015-10-06
SI2392336T1 (sl) 2016-10-28
CY1117174T1 (el) 2017-04-05
HK1161122A1 (en) 2012-08-24
NO340318B1 (no) 2017-03-27
EP2392335A2 (en) 2011-12-07
HUE030010T2 (en) 2017-04-28
SI2392337T1 (sl) 2015-10-30
EP2392337A3 (en) 2012-01-04
ES2590333T3 (es) 2016-11-21
HUE025184T2 (en) 2016-01-28
RS54140B1 (en) 2015-12-31
ME02737B (me) 2015-12-31
SI2392335T1 (sl) 2015-10-30
PL1890705T3 (pl) 2016-05-31
EP2392336B1 (en) 2016-06-22
WO2006119803A1 (en) 2006-11-16
LT2392336T (lt) 2016-10-10
DK1890705T3 (en) 2016-02-01
ES2550204T3 (es) 2015-11-05
CY1117959T1 (el) 2017-05-17
EP2392336A3 (en) 2011-12-28
ES2561614T3 (es) 2016-02-29
EP2392336A2 (en) 2011-12-07

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