JP2012509106A - 中空のマイクロニードルアレイ及び方法 - Google Patents

中空のマイクロニードルアレイ及び方法 Download PDF

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Publication number
JP2012509106A
JP2012509106A JP2011536589A JP2011536589A JP2012509106A JP 2012509106 A JP2012509106 A JP 2012509106A JP 2011536589 A JP2011536589 A JP 2011536589A JP 2011536589 A JP2011536589 A JP 2011536589A JP 2012509106 A JP2012509106 A JP 2012509106A
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JP
Japan
Prior art keywords
microneedles
microneedle
injection
hollow
infusion
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Pending
Application number
JP2011536589A
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English (en)
Japanese (ja)
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JP2012509106A5 (enExample
Inventor
エー. バートン,スコット
エル. フレデリクソン,フランクリン
ジェイ. ハンセン,クリステン
パトリック シンマーズ,ライアン
ティー. フェン,パーシー
エス. モークリー,クレイグ
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3M Innovative Properties Co
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3M Innovative Properties Co
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Publication of JP2012509106A publication Critical patent/JP2012509106A/ja
Publication of JP2012509106A5 publication Critical patent/JP2012509106A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/20Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205Vaccinating by means of needles or other puncturing devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/150022Source of blood for capillary blood or interstitial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150053Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150106Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A61B5/150396Specific tip design, e.g. for improved penetration characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150969Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150977Arrays of piercing elements for simultaneous piercing
    • A61B5/150984Microneedles or microblades
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/04Skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
JP2011536589A 2008-11-18 2009-11-17 中空のマイクロニードルアレイ及び方法 Pending JP2012509106A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11584008P 2008-11-18 2008-11-18
US61/115,840 2008-11-18
PCT/US2009/064742 WO2010059605A2 (en) 2008-11-18 2009-11-17 Hollow microneedle array and method

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016077924A Division JP6334592B2 (ja) 2008-11-18 2016-04-08 中空のマイクロニードルアレイ及び方法

Publications (2)

Publication Number Publication Date
JP2012509106A true JP2012509106A (ja) 2012-04-19
JP2012509106A5 JP2012509106A5 (enExample) 2013-01-10

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Application Number Title Priority Date Filing Date
JP2011536589A Pending JP2012509106A (ja) 2008-11-18 2009-11-17 中空のマイクロニードルアレイ及び方法
JP2016077924A Active JP6334592B2 (ja) 2008-11-18 2016-04-08 中空のマイクロニードルアレイ及び方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016077924A Active JP6334592B2 (ja) 2008-11-18 2016-04-08 中空のマイクロニードルアレイ及び方法

Country Status (13)

Country Link
US (1) US20110213335A1 (enExample)
EP (2) EP3300765A1 (enExample)
JP (2) JP2012509106A (enExample)
KR (3) KR20110086854A (enExample)
CN (2) CN105999538A (enExample)
AU (1) AU2009316789B2 (enExample)
BR (1) BRPI0916150B1 (enExample)
CA (1) CA2742853C (enExample)
ES (1) ES2643606T3 (enExample)
MX (1) MX349292B (enExample)
RU (1) RU2494769C2 (enExample)
SG (1) SG10201500415VA (enExample)
WO (1) WO2010059605A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015136639A1 (ja) * 2014-03-12 2015-09-17 株式会社バイオセレンタック 真皮内目的物質留置用マイクロニードル製剤投与部材及びマイクロニードル製剤迅速投与器具
JP2016517762A (ja) * 2013-05-23 2016-06-20 キンバリー クラーク ワールドワイド インコーポレイテッド 開放チャネル断面形状が改善されたマイクロニードル
JP2020085862A (ja) * 2018-11-30 2020-06-04 花王株式会社 微細突起具の検査方法及び検査装置
WO2024237204A1 (ja) * 2023-05-12 2024-11-21 Asti株式会社 マイクロニードル製造方法とマイクロニードルとマイクロニードルユニット

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2508135C2 (ru) 2009-07-31 2014-02-27 3М Инновейтив Пропертиз Компани Матрица полых микроигл
CA2800253C (en) 2010-05-28 2022-07-12 3M Innovative Properties Company Aqueous formulations for coating microneedle arrays
WO2012074721A2 (en) * 2010-12-02 2012-06-07 Lanco Biosciences, Inc. Delivery of serotonin receptor antagonists by microinjection systems
WO2012098503A1 (en) * 2011-01-18 2012-07-26 Nanopass Technologies Ltd. Medication delivery assembly
EP2753377B1 (en) 2011-09-07 2022-05-04 Kindeva Drug Delivery L.P. Delivery system for hollow microneedle arrays
US20140316333A1 (en) * 2011-10-28 2014-10-23 Sung-Yun Kwon Dissolving solid solution perforator patch for migraine treatment
WO2013082427A1 (en) 2011-11-30 2013-06-06 3M Innovative Properties Company Microneedle device including a peptide therapeutic agent and an amino acid and methods of making and using the same
EP2906284B8 (en) 2012-10-10 2021-01-20 Kindeva Drug Delivery L.P. Force-controlled applicator for applying a microneedle device to skin
US10300260B2 (en) 2012-10-10 2019-05-28 3M Innovative Properties Company Applicator and method for applying a microneedle device to skin
KR102168328B1 (ko) * 2012-10-17 2020-10-22 도판 인사츠 가부시키가이샤 멀티 마이크로 니들 디바이스 사용 유체 주입기 조작 기구
CN104797287B (zh) 2012-11-16 2017-12-26 3M创新有限公司 力控施用装置
US10549079B2 (en) 2012-12-21 2020-02-04 3M Innovative Properties Company Adhesive assemblies and microneedle injection apparatuses comprising same
CN104884119B (zh) 2012-12-27 2018-04-20 3M创新有限公司 具有中空微针的制品及其制备方法
WO2014110016A1 (en) 2013-01-08 2014-07-17 3M Innovative Properties Company Applicator for applying a microneedle device to skin
US10071199B2 (en) 2013-03-15 2018-09-11 Incube Labs, Llc Multi-stage biodegradable drug delivery platform
WO2014153447A2 (en) 2013-03-22 2014-09-25 3M Innovative Properties Company Microneedle applicator comprising a counter assembly
US20140350514A1 (en) * 2013-05-22 2014-11-27 Nanopass Technologies Ltd. Systems and methods for intradermal delivery of therapeutics using microneedles
KR102274902B1 (ko) 2013-05-31 2021-07-07 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로니들 주사 및 주입 장치 및 그의 사용 방법
ES2686362T3 (es) 2013-05-31 2018-10-17 3M Innovative Properties Company Aparato de inyección de microagujas que comprende una accionador inverso
WO2014193727A1 (en) 2013-05-31 2014-12-04 3M Innovative Properties Company Microneedle injection apparatus comprising a dual cover
US10099043B2 (en) 2013-07-16 2018-10-16 3M Innovative Properties Company Hollow microneedle array article
JP6430501B2 (ja) 2013-07-16 2018-11-28 スリーエム イノベイティブ プロパティズ カンパニー 斜角開口部を有する中空マイクロニードル
WO2015009524A1 (en) 2013-07-16 2015-01-22 3M Innovative Properties Company Hollow microneedle with beveled tip
WO2015009531A1 (en) 2013-07-16 2015-01-22 3M Innovative Properties Company Article comprising a microneedle
WO2015034807A2 (en) 2013-09-05 2015-03-12 Merck Sharp & Dohme Corp. Methods of immunization with varicella zoster virus antigen
DE102013219432A1 (de) * 2013-09-26 2015-03-26 Peter Röhr Blutentnahmevorrichtung und Verfahren zum Entnehmen von Blut
GB201403773D0 (en) 2014-03-04 2014-04-16 Univ Cardiff Microneedle based cell delivery
PT3834824T (pt) 2014-03-28 2025-11-18 Univ Duke Tratamento do cancro da mama positivo para o receptor de estrogénio utilizando um modulador seletivo do recetor de estrogénio
RU2719937C1 (ru) * 2014-04-24 2020-04-23 Джорджия Тек Рисёч Корпорейшн Микроиглы и способы их изготовления
AU2016209496B2 (en) 2015-01-21 2018-06-28 Kindeva Drug Delivery L.P. Microneedle array and method of use
CN107206066A (zh) 2015-01-27 2017-09-26 3M创新有限公司 用于微针疫苗贴剂的含明矾的涂层制剂
CA2976376A1 (en) 2015-02-13 2016-08-18 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof
CA2984357A1 (en) 2015-04-29 2016-11-03 Radius Pharmaceuticals, Inc. Methods for treating cancer
CN108135837B (zh) 2015-10-09 2022-05-31 3M创新有限公司 用于涂布微针阵列的锌组合物
US10287543B2 (en) 2015-11-19 2019-05-14 Miltenyi Biotec, Gmbh Process and device for isolating cells from biological tissue
JP2017176652A (ja) 2016-03-31 2017-10-05 花王株式会社 微細中空突起具
JP6732373B2 (ja) 2016-03-31 2020-07-29 花王株式会社 微細中空突起具の製造方法、及び微細中空突起具
EP3481414B1 (en) 2016-04-18 2021-11-03 Radius Health, Inc. Formulations of abaloparatide, transdermal patches thereof, and uses thereof
CN107569238A (zh) * 2016-07-04 2018-01-12 中山大学 一种粘贴式烟囱型微针阵列及其制造方法
FR3054137B1 (fr) * 2016-07-21 2021-08-27 Univ Angers Dispositif medical implantable d’injection locoregionale
JP2019528284A (ja) 2016-08-17 2019-10-10 ファクター バイオサイエンス インコーポレイテッド 核酸産物およびその投与方法
WO2018056584A1 (ko) 2016-09-21 2018-03-29 삼성전자 주식회사 피부 상태 측정 방법 및 이를 위한 전자 장치
EP3318300A1 (en) 2016-11-02 2018-05-09 Miltenyi Biotec GmbH Perfusion device for biological tissue
WO2018124808A1 (ko) * 2016-12-29 2018-07-05 랩앤피플주식회사 마이크로 니들
MX383786B (es) 2017-01-05 2025-03-14 Radius Pharmaceuticals Inc Formas polimorficas de rad1901-2hcl.
US11642453B2 (en) 2017-01-10 2023-05-09 A.T. Still University Fluid infusion system
EP3586906A4 (en) * 2017-02-24 2020-12-30 Hisamitsu Pharmaceutical Co., Inc. MICRO-NEEDLE DEVICE
CN110475582B (zh) * 2017-03-31 2022-06-07 凸版印刷株式会社 经皮给药装置
FR3065648B1 (fr) * 2017-04-28 2020-08-21 Line Paradis Applicateur d'un produit de traitement cosmetique de la peau ou des levres
CN109394236B (zh) * 2017-08-17 2022-04-01 李泉 一种采血装置及其控制设备
JP7284748B2 (ja) 2017-10-17 2023-05-31 キンデーバ ドラッグ デリバリー リミティド パートナーシップ マイクロニードルアレイを皮膚に適用するためのアプリケータ
WO2019166572A1 (en) 2018-02-28 2019-09-06 Pharming Intellectual Property B.V. Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor
KR102137760B1 (ko) 2018-03-23 2020-07-24 (주)지엘캄퍼니 주사기용 마이크로 니들 어레이 및 이를 포함하는 주사기 및 주사기용 마이크로 니들 어레이의 제조 방법
KR102146704B1 (ko) 2018-04-13 2020-08-21 가천대학교 산학협력단 사이클로스포린 A (CsA) 경피 및 피내 약물전달용 마이크로구조체
EP3793440A1 (en) 2018-05-16 2021-03-24 Kindeva Drug Delivery L.P. Microneedle biosensor
AU2019297421B2 (en) 2018-07-04 2024-08-29 Radius Pharmaceuticals, Inc. Polymorphic forms of RAD 1901-2HCL
CN112752591A (zh) 2018-09-24 2021-05-04 欧莱雅 包含用于皮肤着色的微针的装置
CN112752590A (zh) 2018-09-24 2021-05-04 欧莱雅 包含用于皮肤原位反应的微针的装置
EP3856323A1 (en) 2018-09-24 2021-08-04 L'oreal Device comprising microneedles for cosmetic fillers delivery
SG11202104838SA (en) * 2018-12-03 2021-06-29 Eirion Therapeutics Inc Improved delivery of large agents
TWI826603B (zh) 2018-12-06 2023-12-21 愛爾蘭商索塔醫療愛爾蘭有限公司 治療組織之微刀片結構及方法
KR102187439B1 (ko) * 2019-01-30 2020-12-07 주식회사 라파스 마이크로니들 패취를 이용한 최소 침습적 피부 생체 검사 방법
MX2021009569A (es) 2019-02-12 2021-09-08 Radius Pharmaceuticals Inc Procesos y compuestos.
KR20200120231A (ko) 2019-04-12 2020-10-21 연세대학교 산학협력단 신부전증 치료를 위한 동정맥루 마이크로 니들
CN114450265B (zh) 2019-07-03 2024-12-24 菲克特生物科学股份有限公司 阳离子脂质及其用途
US10501404B1 (en) 2019-07-30 2019-12-10 Factor Bioscience Inc. Cationic lipids and transfection methods
CN111803278A (zh) * 2020-07-20 2020-10-23 中国人民解放军陆军军医大学 一种内置装载微囊和微针注射功能的复合式创伤急救敷料
KR102297883B1 (ko) 2021-02-17 2021-09-03 주식회사 지엘캄퍼니 마이크로 니들조립체
US12357804B2 (en) 2021-03-01 2025-07-15 Deka Products Limited Partnership Medical agent dispensing systems, methods, and apparatuses
CA3210642A1 (en) 2021-03-01 2022-09-09 Dean Kamen Medical agent dispensing apparatuses, systems, and methods
US12161832B2 (en) 2021-03-01 2024-12-10 Deka Products Limited Partnership Medical agent dispensing systems, methods, and apparatuses
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
WO2023196674A1 (en) * 2022-04-08 2023-10-12 Hearthero, Inc. Automated external defibrillator with integrated medication delivery
WO2024097385A1 (en) 2022-11-05 2024-05-10 Kindeva Drug Delivery L.P. Microneedle array applicator and system
AU2023395786A1 (en) 2022-12-16 2025-07-31 Kindeva Drug Delivery L.P. Drug delivery device

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002511317A (ja) * 1998-04-10 2002-04-16 マイルストーン サイアンティフィック インク 圧力または力の少なくともいずれか一方をコンピュータ制御した薬物投与装置および同様の装置
WO2003074102A2 (en) * 2002-03-04 2003-09-12 Nano Pass Technologies Ltd. Devices and methods for transporting fluid across a biological barrier
JP2005021677A (ja) * 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベース、及び注射針
US20050256499A1 (en) * 2004-03-03 2005-11-17 Pettis Ronald J Methods and devices for improving delivery of a substance to skin
JP2006510467A (ja) * 2002-10-11 2006-03-30 ベクトン・ディキンソン・アンド・カンパニー 単一針または多針皮内(id)送達装置に結合されたフィードバックまたはモデルベースコントローラを使用して患者の体内の物質の濃度の連続長期制御を開始し維持するためのシステムおよび方法
US7285113B2 (en) * 2000-03-09 2007-10-23 Nanopass Technologies Ltd. Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems
WO2008020633A1 (en) * 2006-08-18 2008-02-21 Toppan Printing Co., Ltd. Microneedle and microneedle patch
WO2008053481A1 (en) * 2006-11-01 2008-05-08 Svip 6 Llc Microneedle arrays

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5457A (en) * 1848-02-22 Behch-vise
JP4118356B2 (ja) * 1996-12-12 2008-07-16 日本ペイント株式会社 防汚塗料組成物
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
GB9815820D0 (en) * 1998-07-22 1998-09-16 Secr Defence Improvements relating to micro-machining
US7048723B1 (en) * 1998-09-18 2006-05-23 The University Of Utah Research Foundation Surface micromachined microneedles
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US8465468B1 (en) * 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
US6558361B1 (en) * 2000-03-09 2003-05-06 Nanopass Ltd. Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems
ATE428357T1 (de) * 2000-10-13 2009-05-15 Alza Corp Vorrichtung und verfahren zum durchstechen der haut mit micronadeln
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US20070005017A1 (en) * 2002-02-04 2007-01-04 Becton, Dickinson And Company Intradermal delivery device with crenellated skin engaging surface geometry
CA2492867C (en) 2002-07-19 2011-07-05 3M Innovative Properties Company Microneedle devices and microneedle delivery apparatus
AU2003270085A1 (en) 2002-09-03 2004-03-29 University Of Virginia Patent Foundation Blast and ballistic protection systems and method of making the same
US20060184101A1 (en) * 2003-04-21 2006-08-17 Ravi Srinivasan Microjet devices and methods for drug delivery
WO2004108203A1 (ja) * 2003-06-10 2004-12-16 Medrx Co., Ltd. 経皮投薬用パッドベース、及び注射針
GB2416203B (en) 2004-07-13 2007-03-07 Microsulis Ltd Motion rate sensor
US8016811B2 (en) * 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
WO2005065765A1 (en) 2003-12-29 2005-07-21 3M Innovative Properties Company Medical devices and kits including same
WO2005082596A1 (en) * 2004-02-23 2005-09-09 3M Innovative Properties Company Method of molding for microneedle arrays
CA2559640C (en) * 2004-03-19 2010-11-30 Pfizer Health Ab Means for transdermal administration of nicotine
EP3329960A1 (en) 2004-06-10 2018-06-06 3M Innovative Properties Company Patch application device and kit
GB0427762D0 (en) * 2004-12-17 2005-01-19 Functional Microstructures Ltd Device and method for transport across barrier
JP2008520367A (ja) 2004-11-18 2008-06-19 スリーエム イノベイティブ プロパティズ カンパニー 皮膚非接触型のマイクロニードルアレイアプリケータ
DE602005027397D1 (de) 2004-11-18 2011-05-19 3M Innovative Properties Co Mikronadelanordungsapplikator und halter
EP2067599B1 (en) 2004-12-07 2016-10-26 3M Innovative Properties Company Method of molding a microneedle
WO2006062848A1 (en) 2004-12-10 2006-06-15 3M Innovative Properties Company Medical device
WO2006101459A1 (en) * 2005-03-23 2006-09-28 Agency For Science, Technology And Research Microneedles
US10035008B2 (en) 2005-04-07 2018-07-31 3M Innovative Properties Company System and method for tool feedback sensing
US20080269666A1 (en) * 2005-05-25 2008-10-30 Georgia Tech Research Corporation Microneedles and Methods for Microinfusion
WO2006135794A2 (en) 2005-06-10 2006-12-21 3M Innovative Properties Company Method of making a micromould and a micromoulded article
WO2007002523A2 (en) 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
CA2613114C (en) 2005-06-27 2015-02-24 3M Innovative Properties Company Microneedle cartridge assembly and method of applying
JP5144510B2 (ja) 2005-06-27 2013-02-13 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイ適用装置
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
CA2650197A1 (en) * 2006-05-09 2008-02-28 Apogee Technology, Inc. Nanofiber structures on asperities for sequestering, carrying and transferring substances
US20080008745A1 (en) * 2006-06-21 2008-01-10 University Of Kentucky Research Foundation Transdermal delivery of naltrexone hydrochloride, naltrexol hydrochloride, and bis(hydroxy-methyl)propionyl-3-0 ester naltrexone using microneedles
DE102006040642A1 (de) * 2006-08-30 2008-03-13 Robert Bosch Gmbh Mikronadeln zur Platzierung in der Haut zwecks transdermaler Applikation von Pharmazeutika
AU2008302158A1 (en) * 2007-09-20 2009-03-26 Transport Pharmaceuticals, Inc. Method of enhancing iontophoretic delivery of a peptide

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002511317A (ja) * 1998-04-10 2002-04-16 マイルストーン サイアンティフィック インク 圧力または力の少なくともいずれか一方をコンピュータ制御した薬物投与装置および同様の装置
US7285113B2 (en) * 2000-03-09 2007-10-23 Nanopass Technologies Ltd. Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems
WO2003074102A2 (en) * 2002-03-04 2003-09-12 Nano Pass Technologies Ltd. Devices and methods for transporting fluid across a biological barrier
JP2006510467A (ja) * 2002-10-11 2006-03-30 ベクトン・ディキンソン・アンド・カンパニー 単一針または多針皮内(id)送達装置に結合されたフィードバックまたはモデルベースコントローラを使用して患者の体内の物質の濃度の連続長期制御を開始し維持するためのシステムおよび方法
JP2005021677A (ja) * 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベース、及び注射針
US20050256499A1 (en) * 2004-03-03 2005-11-17 Pettis Ronald J Methods and devices for improving delivery of a substance to skin
WO2008020633A1 (en) * 2006-08-18 2008-02-21 Toppan Printing Co., Ltd. Microneedle and microneedle patch
WO2008053481A1 (en) * 2006-11-01 2008-05-08 Svip 6 Llc Microneedle arrays

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016517762A (ja) * 2013-05-23 2016-06-20 キンバリー クラーク ワールドワイド インコーポレイテッド 開放チャネル断面形状が改善されたマイクロニードル
WO2015136639A1 (ja) * 2014-03-12 2015-09-17 株式会社バイオセレンタック 真皮内目的物質留置用マイクロニードル製剤投与部材及びマイクロニードル製剤迅速投与器具
JPWO2015136639A1 (ja) * 2014-03-12 2017-04-06 株式会社バイオセレンタック 真皮内目的物質留置用マイクロニードル製剤投与部材及びマイクロニードル製剤迅速投与器具
US10342964B2 (en) 2014-03-12 2019-07-09 Labo Juversa Co., Ltd. Microneedle preparation administration member for placement of objective substance in dermis, and apparatus for quick administration of microneedle preparation
JP2020085862A (ja) * 2018-11-30 2020-06-04 花王株式会社 微細突起具の検査方法及び検査装置
JP7385352B2 (ja) 2018-11-30 2023-11-22 花王株式会社 微細突起具の検査方法及び製造方法
WO2024237204A1 (ja) * 2023-05-12 2024-11-21 Asti株式会社 マイクロニードル製造方法とマイクロニードルとマイクロニードルユニット

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