JP2012508791A5 - - Google Patents
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- Publication number
- JP2012508791A5 JP2012508791A5 JP2011543839A JP2011543839A JP2012508791A5 JP 2012508791 A5 JP2012508791 A5 JP 2012508791A5 JP 2011543839 A JP2011543839 A JP 2011543839A JP 2011543839 A JP2011543839 A JP 2011543839A JP 2012508791 A5 JP2012508791 A5 JP 2012508791A5
- Authority
- JP
- Japan
- Prior art keywords
- oil composition
- oil
- edible
- acid
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 27
- 239000008157 edible vegetable oil Substances 0.000 claims 15
- YUFFSWGQGVEMMI-JLNKQSITSA-N (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O YUFFSWGQGVEMMI-JLNKQSITSA-N 0.000 claims 11
- 235000021294 Docosapentaenoic acid Nutrition 0.000 claims 10
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 10
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 10
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 10
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 10
- 238000004519 manufacturing process Methods 0.000 claims 10
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims 10
- 235000014107 unsaturated dietary fats Nutrition 0.000 claims 8
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 6
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 6
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 claims 3
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 claims 3
- 201000001320 Atherosclerosis Diseases 0.000 claims 3
- 229940090949 docosahexaenoic acid Drugs 0.000 claims 3
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 claims 3
- 239000003921 oil Substances 0.000 claims 3
- 235000019198 oils Nutrition 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 2
- 102000003896 Myeloperoxidases Human genes 0.000 claims 2
- 108090000235 Myeloperoxidases Proteins 0.000 claims 2
- 235000019483 Peanut oil Nutrition 0.000 claims 2
- 239000003963 antioxidant agent Substances 0.000 claims 2
- 235000006708 antioxidants Nutrition 0.000 claims 2
- 239000008162 cooking oil Substances 0.000 claims 2
- 235000021281 monounsaturated fatty acids Nutrition 0.000 claims 2
- 239000000312 peanut oil Substances 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 150000004671 saturated fatty acids Chemical class 0.000 claims 2
- 235000003441 saturated fatty acids Nutrition 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 235000015112 vegetable and seed oil Nutrition 0.000 claims 2
- 239000008158 vegetable oil Substances 0.000 claims 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims 1
- 235000019485 Safflower oil Nutrition 0.000 claims 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims 1
- 229930003316 Vitamin D Natural products 0.000 claims 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims 1
- 239000000828 canola oil Substances 0.000 claims 1
- 235000019519 canola oil Nutrition 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000003240 coconut oil Substances 0.000 claims 1
- 235000019864 coconut oil Nutrition 0.000 claims 1
- 238000010411 cooking Methods 0.000 claims 1
- 235000005687 corn oil Nutrition 0.000 claims 1
- 239000002285 corn oil Substances 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 230000000378 dietary effect Effects 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 238000009826 distribution Methods 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 235000021323 fish oil Nutrition 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000004006 olive oil Substances 0.000 claims 1
- 235000008390 olive oil Nutrition 0.000 claims 1
- 239000000419 plant extract Substances 0.000 claims 1
- 235000005713 safflower oil Nutrition 0.000 claims 1
- 239000003813 safflower oil Substances 0.000 claims 1
- 229940119224 salmon oil Drugs 0.000 claims 1
- 239000008159 sesame oil Substances 0.000 claims 1
- 235000011803 sesame oil Nutrition 0.000 claims 1
- 239000003549 soybean oil Substances 0.000 claims 1
- 235000012424 soybean oil Nutrition 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 235000019155 vitamin A Nutrition 0.000 claims 1
- 239000011719 vitamin A Substances 0.000 claims 1
- 235000019166 vitamin D Nutrition 0.000 claims 1
- 239000011710 vitamin D Substances 0.000 claims 1
- 150000003710 vitamin D derivatives Chemical class 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
- 229940045997 vitamin a Drugs 0.000 claims 1
- 229940046008 vitamin d Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11482308P | 2008-11-14 | 2008-11-14 | |
| US61/114,823 | 2008-11-14 | ||
| PCT/IB2009/007669 WO2010055419A2 (en) | 2008-11-14 | 2009-11-10 | A method of lowering circulating oxidized low density lipoprotein-beta-2-glycoprotein 1 complex for treatment of atherosclerosclerosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015002682A Division JP2015091855A (ja) | 2008-11-14 | 2015-01-08 | アテローム性動脈硬化症の治療のための循環酸化低密度リポタンパク質‐ベータ‐２‐糖タンパク質１複合体を減少させる方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012508791A JP2012508791A (ja) | 2012-04-12 |
| JP2012508791A5 true JP2012508791A5 (enExample) | 2012-12-27 |
Family
ID=42170470
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543839A Pending JP2012508791A (ja) | 2008-11-14 | 2009-11-10 | アテローム性動脈硬化症の治療のための循環酸化低密度リポタンパク質‐ベータ‐２‐糖タンパク質１複合体を減少させる方法 |
| JP2015002682A Pending JP2015091855A (ja) | 2008-11-14 | 2015-01-08 | アテローム性動脈硬化症の治療のための循環酸化低密度リポタンパク質‐ベータ‐２‐糖タンパク質１複合体を減少させる方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015002682A Pending JP2015091855A (ja) | 2008-11-14 | 2015-01-08 | アテローム性動脈硬化症の治療のための循環酸化低密度リポタンパク質‐ベータ‐２‐糖タンパク質１複合体を減少させる方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9446013B2 (enExample) |
| EP (1) | EP2355812B1 (enExample) |
| JP (2) | JP2012508791A (enExample) |
| KR (1) | KR20110098909A (enExample) |
| CN (1) | CN102202661A (enExample) |
| AU (1) | AU2009315314B2 (enExample) |
| BR (1) | BRPI0915247A2 (enExample) |
| CA (1) | CA2743434C (enExample) |
| DK (1) | DK2355812T3 (enExample) |
| MX (1) | MX2011005077A (enExample) |
| WO (1) | WO2010055419A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8952000B2 (en) | 2011-02-16 | 2015-02-10 | Pivotal Therapeutics Inc. | Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events |
| US9119826B2 (en) | 2011-02-16 | 2015-09-01 | Pivotal Therapeutics, Inc. | Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels |
| US8715648B2 (en) | 2011-02-16 | 2014-05-06 | Pivotal Therapeutics Inc. | Method for treating obesity with anti-obesity formulations and omega 3 fatty acids for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics |
| US8951514B2 (en) | 2011-02-16 | 2015-02-10 | Pivotal Therapeutics Inc. | Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels |
| NO344004B1 (en) * | 2017-06-23 | 2019-08-12 | Olivita As | Combination of oils |
| WO2021080951A1 (en) * | 2019-10-21 | 2021-04-29 | President And Fellows Of Harvard College | Compositions and methods for detection of oxidizable analytes |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8524275D0 (en) * | 1985-10-02 | 1985-11-06 | Efamol Ltd | Pharmaceutical & dietary compositions |
| US4681893A (en) | 1986-05-30 | 1987-07-21 | Warner-Lambert Company | Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis |
| GB2238476A (en) * | 1989-11-04 | 1991-06-05 | K T Lalvani | Therapeutic aquatic animal and garlic products |
| US5631365A (en) | 1993-09-21 | 1997-05-20 | Schering Corporation | Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents |
| IT1274734B (it) * | 1994-08-25 | 1997-07-24 | Prospa Bv | Composizioni farmaceutiche contenenti acidi grassi poliinsaturi, loro esteri o sali, unitamente a vitamine o provitamine antiossidanti |
| US5578334A (en) * | 1995-04-07 | 1996-11-26 | Brandeis University | Increasing the HDL level and the HDL/LDL ratio in human serum with fat blends |
| IT1277953B1 (it) * | 1995-12-21 | 1997-11-12 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per |
| DE19855426A1 (de) * | 1998-12-02 | 2000-06-08 | Wolfgang Langhoff | Mittel zur Therapie und Prophylaxe von rheumatisch-arthritischen Erkrankungen und zur Prophylaxe von cardiovaskulären Erkrankungen |
| JP2001346517A (ja) * | 2000-06-02 | 2001-12-18 | K-Tac Planners Co Ltd | 食用油脂。 |
| DE20105126U1 (de) * | 2001-03-23 | 2002-01-31 | Bartz, Volker, 35440 Linden | Fischöl zur oralen Einnahme |
| GB0210212D0 (en) * | 2002-05-03 | 2002-06-12 | Univ Southampton | Effects of dietary N-3 and N-6 pufa intake on atheromatous plaque stability |
| EP1501493B1 (en) * | 2002-05-03 | 2009-10-07 | Pronova BioPharma Norge AS | Use of epa and dha in secondary prevention of strokes |
| ES2254018B2 (es) * | 2004-11-16 | 2009-01-01 | Universidad Autonoma De Madrid | Mezcla oleosa de ingredientes bioactivos naturales para la preparacion de un producto alimenticio enriquecido. |
| PT1876906E (pt) * | 2005-04-29 | 2009-12-15 | Vinorica S L | Suplemento alimentar ou alimento funcional contendo uma combinação de óleos |
| US20090252853A1 (en) * | 2005-11-30 | 2009-10-08 | Angel Gil Hernandez | Lipid Mixture and Use Thereof in the Preparation of a Product That Is Intended for Enteral or Oral Administration |
| PL1800675T4 (pl) * | 2005-12-23 | 2012-02-29 | Nutricia Nv | Kompozycja zawierająca wielonienasycone kwasy tłuszczowe, białka, mangan, i/lub molibden oraz nukleozydy/nukleotydy do leczenia otępienia |
| JP5099808B2 (ja) * | 2006-05-29 | 2012-12-19 | 独立行政法人農業・食品産業技術総合研究機構 | 脂質代謝改善用組成物 |
| WO2008088415A1 (en) * | 2006-10-18 | 2008-07-24 | Reliant Pharmaceuticals, Inc. | Omega-3 fatty acids for reduction of lp-pla2 levels |
| US20090270502A1 (en) * | 2007-01-11 | 2009-10-29 | Carotino Sdn. Bhd. | Method for Lowering Risk of Cardiovascular Diseases |
-
2009
- 2009-11-10 CA CA2743434A patent/CA2743434C/en active Active
- 2009-11-10 BR BRPI0915247A patent/BRPI0915247A2/pt not_active Application Discontinuation
- 2009-11-10 MX MX2011005077A patent/MX2011005077A/es active IP Right Grant
- 2009-11-10 DK DK09825826.2T patent/DK2355812T3/da active
- 2009-11-10 EP EP09825826.2A patent/EP2355812B1/en active Active
- 2009-11-10 CN CN2009801442637A patent/CN102202661A/zh active Pending
- 2009-11-10 WO PCT/IB2009/007669 patent/WO2010055419A2/en not_active Ceased
- 2009-11-10 AU AU2009315314A patent/AU2009315314B2/en active Active
- 2009-11-10 JP JP2011543839A patent/JP2012508791A/ja active Pending
- 2009-11-10 US US13/125,806 patent/US9446013B2/en active Active - Reinstated
- 2009-11-10 KR KR1020117013499A patent/KR20110098909A/ko not_active Ceased
-
2015
- 2015-01-08 JP JP2015002682A patent/JP2015091855A/ja active Pending
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